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Select item 97339371.

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos

Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437

PMCID:: PMC9733937

Abstract Article PDF–2.2M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73220673.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 72024064.

Association of ICAM3 Genetic Variant with Severe Acute Respiratory Syndrome

Kelvin Y. K. Chan, Johannes C. Y. Ching, M. S. Xu, Annie N. Y. Cheung, Shea-Ping Yip, Loretta Y. C. Yam, Sik-To Lai, Chung-Ming Chu, Andrew T. Y. Wong, You-Qiang Song, Fang-Ping Huang, Wei Liu, P. H. Chung, G. M. Leung, Eudora Y. D. Chow, Eric Y. T. Chan, Jane C. K. Chan, Hextan Ngan, Paul Tam, Li-Chong Chan, Pak Sham, Vera S. F. Chan, Malik Peiris, Steve C. L. Lin, Ui-Soon Khoo

J Infect Dis. 2007 Jul 15; 196(2): 271–280. Published online 2007 Jul 15. doi: 10.1086/518892

PMCID:: PMC7202406

Abstract Article PDF–293K

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 70378606.

Changes in the Surface Expression of Intercellular Adhesion Molecule 3, the Induction of Apoptosis, and the Inhibition of Cell-Cycle Progression of Human Multidrug-Resistant Jurkat/A4 Cells Exposed to a Random Positioning Machine

Alisa Sokolovskaya, Ekaterina Korneeva, Danila Zaichenko, Edward Virus, Dmitry Kolesov, Aleksey Moskovtsev, Aslan Kubatiev

Int J Mol Sci. 2020 Feb; 21(3): 855. Published online 2020 Jan 28. doi: 10.3390/ijms21030855

PMCID:: PMC7037860

Abstract Article PDF–2.9M

Select item 59287987.

ICAM3 mediates inflammatory signaling to promote cancer cell stemness

Wenzhi Shen, Junling Xie, Shuangtao Zhao, Renle Du, Xiaohe Luo, Huiwen He, Shan Jiang, Na Hao, Chong Chen, Chunlei Guo, Yanhua Liu, Yanan Chen, Peiqing Sun, Shengyong Yang, Na Luo, Rong Xiang, Yunping Luo

Cancer Lett. Author manuscript; available in PMC 2018 May 28.

Published in final edited form as: Cancer Lett. 2018 May 28; 422: 29–43. Published online 2018 Mar 2. doi: 10.1016/j.canlet.2018.02.034

PMCID:: PMC5928798

Abstract Article PDF–1.2M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 53222489.

Increased cell adhesion molecules, PECAM-1, ICAM-3, or VCAM-1, predict increased risk for flare in patients with quiescent inflammatory bowel disease

Phillip Gu, Arianne Theiss, Jie Han, Linda A. Feagins

J Clin Gastroenterol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: J Clin Gastroenterol. 2017 Jul; 51(6): 522–527. doi: 10.1097/MCG.0000000000000618

PMCID:: PMC5322248

Abstract Article PDF–271K

Select item 492871610.

HIV–host interactome revealed directly from infected cells

Yang Luo, Erica Y. Jacobs, Todd M. Greco, Kevin D. Mohammed, Tommy Tong, Sarah Keegan, James M. Binley, Ileana M. Cristea, David Fenyö, Michael P. Rout, Brian T. Chait, Mark A. Muesing

Nat Microbiol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Nat Microbiol. 2016 Jul; 1(7): 16068. Published online 2016 May 23. doi: 10.1038/nmicrobiol.2016.68

PMCID:: PMC4928716

Abstract Article PDF–1.1M

Select item 363685611.

The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes

Daniel Perez-Hernandez, Cristina Gutiérrez-Vázquez, Inmaculada Jorge, Soraya López-Martín, Angeles Ursa, Francisco Sánchez-Madrid, Jesús Vázquez, María Yáñez-Mó

J Biol Chem. 2013 Apr 26; 288(17): 11649–11661. Published online 2013 Mar 5. doi: 10.1074/jbc.M112.445304

PMCID:: PMC3636856

Abstract Article PDF–4.6M

Select item 349259112.

Characterization of a Distinct Population of Circulating Human Non-Adherent Endothelial Forming Cells and Their Recruitment via Intercellular Adhesion Molecule-3

Sarah L. Appleby, Michaelia P. Cockshell, Jyotsna B. Pippal, Emma J. Thompson, Jeffrey M. Barrett, Katie Tooley, Shaundeep Sen, Wai Yan Sun, Randall Grose, Ian Nicholson, Vitalina Levina, Ira Cooke, Gert Talbo, Angel F. Lopez, Claudine S. Bonder

PLoS One. 2012; 7(11): e46996. Published online 2012 Nov 7. doi: 10.1371/journal.pone.0046996

PMCID:: PMC3492591

Abstract Article PDF–3.5M

Select item 334013613.

Activated Apoptotic Cells Induce Dendritic Cell Maturation via Engagement of Toll-like Receptor 4 (TLR4), Dendritic Cell-specific Intercellular Adhesion Molecule 3 (ICAM-3)-grabbing Nonintegrin (DC-SIGN), and β2 Integrins

Sushil Kumar Pathak, Annette E. Sköld, Venkatramanan Mohanram, Catrine Persson, Ulrika Johansson, Anna-Lena Spetz

J Biol Chem. 2012 Apr 20; 287(17): 13731–13742. Published online 2012 Mar 6. doi: 10.1074/jbc.M111.336545

PMCID:: PMC3340136

Abstract Article PDF–2.6M

Select item 331556914.

RUNX3 Regulates Intercellular Adhesion Molecule 3 (ICAM-3) Expression during Macrophage Differentiation and Monocyte Extravasation

Ana Estecha, Noemí Aguilera-Montilla, Paloma Sánchez-Mateos, Amaya Puig-Kröger

PLoS One. 2012; 7(3): e33313. Published online 2012 Mar 29. doi: 10.1371/journal.pone.0033313

PMCID:: PMC3315569

Abstract Article PDF–1.4M

Select item 330798715.

Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells

E E Torr, D H Gardner, L Thomas, D M Goodall, A Bielemeier, R Willetts, H R Griffiths, L J Marshall, A Devitt

Cell Death Differ. 2012 Apr; 19(4): 671–679. Published online 2011 Nov 25. doi: 10.1038/cdd.2011.167

PMCID:: PMC3307987

Abstract Article PDF–570K

Select item 329955116.

Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci

Andre Franke, Dermot P.B. McGovern, Jeffrey C. Barrett, Kai Wang, Graham L. Radford-Smith, Tariq Ahmad, Charlie W. Lees, Tobias Balschun, James Lee, Rebecca Roberts, Carl A. Anderson, Joshua C. Bis, Suzanne Bumpstead, David Ellinghaus, Eleonora M. Festen, Michel Georges, Talin Haritunians, Luke Jostins, Anna Latiano, Christopher G. Mathew, Grant W. Montgomery, Natalie J. Prescott, Jerome I. Rotter, Philip Schumm, Yashoda Sharma, Lisa A. Simms, Kent D. Taylor, David Whiteman, Cisca Wijmenga, Robert N. Baldassano, Murray Barclay, Theodore M. Bayless, Stephan Brand, Carsten Buning, Albert Cohen, Jean-Frederick Colombel, Mario Cottone, Laura Stronati, Ted Denson, Martine De Vos, Renata D’Inca, Marla Dubinsky, Cathryn Edwards, Tim Florin, Denis Franchimont, Richard Gearry, Jürgen Glas, Andre Van Gossum, Stephen L. Guthery, Jonas Halfvarson, Daan Hommes, Jean-Pierre Hugot, Debby Laukens, Ian Lawrance, Marc Lemann, Arie Levine, Cecile Libioulle, Edouard Louis, Craig Mowat, William Newman, Julián Panés, Anne Phillips, Deborah D. Proctor, Miguel Regueiro, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, Frank Seibold, A. Hillary Steinhart, Pieter C.F. Stokkers, Leif Torkvist, Gerd Kullak Ublick, Soumya Raychaudhuri, Todd Green, Thomas Walters, Stephan R. Targan, Steven R. Brant, John D. Rioux, Mauro D’Amato, Rinse Weersma, Subra Kugathasan, Anne M. Griffiths, John C. Mansfield, Severine Vermeire, Richard H. Duerr, Mark S. Silverberg, Jack Satsangi, Stefan Schreiber, Judy H. Cho, Vito Annese, Hakon Hakonarson, Mark J. Daly, Miles Parkes

Nat Genet. Author manuscript; available in PMC 2012 Mar 12.

Published in final edited form as: Nat Genet. 2010 Dec; 42(12): 1118–1125. doi: 10.1038/ng.717

PMCID:: PMC3299551

Article PDF–864K

Select item 328534717.

Retagging Identifies Dendritic Cell-specific Intercellular Adhesion Molecule-3 (ICAM3)-grabbing Non-integrin (DC-SIGN) Protein as a Novel Receptor for a Major Allergen from House Dust Mite

Mohamed Emara, Pierre-Joseph Royer, Jafar Mahdavi, Farouk Shakib, Amir M. Ghaemmaghami

J Biol Chem. 2012 Feb 17; 287(8): 5756–5763. Published online 2011 Dec 28. doi: 10.1074/jbc.M111.312520

PMCID:: PMC3285347

Abstract Article PDF–945K

Select item 323218218.

Polymorphisms in integrin genes and lymphoma risk

Min Shen, Tongzhang Zheng, Qing Lan, Yawei Zhang, H. Dean Hosgood, III, Shelia H. Zahm, Theodore R. Holford, Brian Leaderer, Meredith Yeager, Jeff Yuenger, Stephen Chanock, Nathaniel Rothman

Leuk Res. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Leuk Res. 2011 Jul; 35(7): 968–970. Published online 2011 Jan 15. doi: 10.1016/j.leukres.2010.12.012

PMCID:: PMC3232182

Abstract Article PDF–295K

Select item 319082619.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907