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Select item 111598881.

Potential biomarkers involving IKK/RelA signal in early stage non‐small cell lung cancer

Xianqing Jin, Ziming Wang, Lin Qiu, Dianliang Zhang, Zhenhua Guo, Zongwei Gao, Chun Deng, Fuling Wang, Shan Wang, Chunbao Guo

Cancer Sci. 2008 Mar; 99(3): 582–589. Published online 2008 Jan 21. doi: 10.1111/j.1349-7006.2007.00713.x

PMCID:: PMC11159888

Abstract Article PDF–254K

Select item 111154962.

Annexin A4 interacts with the NF-κB p50 subunit and modulates NF-κB transcriptional activity in a Ca²⁺-dependent manner

Young-Joo Jeon, Do-Hyung Kim, Hyeyun Jung, Sang J. Chung, Seung-Wook Chi, Sayeon Cho, Sang Chul Lee, Byoung Chul Park, Sung Goo Park, Kwang-Hee Bae

Cell Mol Life Sci. 2010 Jul; 67(13): 2271–2281. Published online 2010 Mar 18. doi: 10.1007/s00018-010-0331-9

PMCID:: PMC11115496

Abstract Article PDF–659K

Select item 111099453.

WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination

Jie Zhang, Yuanyuan Yu, Xiuqun Zou, Yaning Du, Qiankun Liang, Mengyao Gong, Yurong He, Junqi Luo, Dandan Wu, Xiaoli Jiang, Matt Sinclair, Emad Tajkhorshid, Hong-Zhuan Chen, Zhaoyuan Hou, Yuejuan Zheng, Lin-Feng Chen, Xiao-Dong Yang

Nucleic Acids Res. 2024 May 22; 52(9): 4969–4984. Published online 2024 Mar 7. doi: 10.1093/nar/gkae161

PMCID:: PMC11109945

Abstract Article PDF–1.6M

Select item 110916374.

Renal ischaemia-reperfusion injury is promoted by transcription factor NF-kB p65, which inhibits TRPC6 expression by activating miR-150

Shuangyu Li, Qiubo Ma, Zengwei Ma, Ying Shi, Xiaoyan Yu, Baohua Gu, Shanshan Sun, Chunlei Yu, Lei Pang

Clin Hemorheol Microcirc. 2024; 86(3): 369–382. Prepublished online 2023 Nov 10. Published online 2024 Apr 10. doi: 10.3233/CH-231979

PMCID:: PMC11091637

Abstract Article PDF–742K

Select item 110116875.

A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells

Yamin Liu, Jieru Yang, Dunchu Weng, Yajun Xie

Int J Mol Sci. 2024 Apr; 25(7): 3576. Published online 2024 Mar 22. doi: 10.3390/ijms25073576

PMCID:: PMC11011687

Abstract Article PDF–4.9M

Select item 109485316.

The NF-κB RelA transcription factor is not required for CD8+ T-cell function in acute viral infection and cancer

Allison Voisin, Maud Plaschka, Marlène Perrin-Niquet, Julie Twardowski, Insaf Boutemine, Baptiste Eluard, Guilhem Lalle, Pierre Stéphan, Khaled Bouherrou, Laurie Tonon, Roxane Pommier, Anthony Ferrari, Ulf Klein, Mélanie Wencker, Véronique Baud, Philippe A. Cassier, Yenkel Grinberg-Bleyer

Front Immunol. 2024; 15: 1379777. Published online 2024 Mar 5. doi: 10.3389/fimmu.2024.1379777

PMCID:: PMC10948531

Abstract Article PDF–5.7M

Select item 109320217.

The Prolonged Activation of the p65 Subunit of the NF-Kappa-B Nuclear Factor Sustains the Persistent Effect of Advanced Glycation End Products on Inflammatory Sensitization in Macrophages

Sayonara Ivana Santos de Assis, Leonardo Szalo Amendola, Maristela Mitiko Okamoto, Guilherme da Silva Ferreira, Rodrigo Tallada Iborra, Danielle Ribeiro Santos, Monique de Fátima Mello Santana, Kelly Gomes Santana, Maria Lucia Correa-Giannella, Denise Frediani Barbeiro, Francisco Garcia Soriano, Ubiratan Fabres Machado, Marisa Passarelli

Int J Mol Sci. 2024 Mar; 25(5): 2713. Published online 2024 Feb 27. doi: 10.3390/ijms25052713

PMCID:: PMC10932021

Abstract Article PDF–2.4M

Select item 107306198.

Nuclear RPSA senses viral nucleic acids to promote the innate inflammatory response

Yan Jiang, Siqi Sun, Yuan Quan, Xin Wang, Yuling You, Xiao Zhang, Yue Zhang, Yin Liu, Bingjing Wang, Henan Xu, Xuetao Cao

Nat Commun. 2023; 14: 8455. Published online 2023 Dec 20. doi: 10.1038/s41467-023-43784-0

Correction in:: Nat Commun. 2024; 15: 855.

PMCID:: PMC10730619

Abstract Article PDF–2.4M

Select item 107154959.

CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma

Xiaomeng Liu, Rong Tang, Jin Xu, Zhen Tan, Chen Liang, Qingcai Meng, Yubin Lei, Jie Hua, Yiyin Zhang, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Si Shi

Gut. 2023 Dec; 72(12): 2329–2343. Published online 2023 Aug 4. doi: 10.1136/gutjnl-2022-329349

PMCID:: PMC10715495

Abstract Article PDF–16M

Select item 1059098210.

The kinesin-14 family motor protein KIFC2 promotes prostate cancer progression by regulating p65

Xinyu Liu, Yu Lin, Weibing Long, Renzheng Yi, Xiongfeng Zhang, Chaoqun Xie, Na Jin, Ziran Qiu, Xiaobing Liu

J Biol Chem. 2023 Nov; 299(11): 105253. Published online 2023 Sep 14. doi: 10.1016/j.jbc.2023.105253

PMCID:: PMC10590982

Abstract Article PDF–5.3M

Select item 1058592411.

Paracrine activin B-NF-κB signaling shapes an inflammatory tumor microenvironment in gastric cancer via fibroblast reprogramming

Yangbing Jin, Qu Cai, Lingquan Wang, Jun Ji, Ying Sun, Jinling Jiang, Chao Wang, Junwei Wu, Benyan Zhang, Liqin Zhao, Feng Qi, Beiqin Yu, Jun Zhang

J Exp Clin Cancer Res. 2023; 42: 269. Published online 2023 Oct 19. doi: 10.1186/s13046-023-02861-4

PMCID:: PMC10585924

Abstract Article PDF–12M

Select item 1040395012.

Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

Longyuan Zhou, Liguo Zhu, Xiaomin Wu, Shixian Hu, Shenghong Zhang, Min Ning, Jun Yu, Minhu Chen

BMC Med. 2023; 21: 287. Published online 2023 Aug 4. doi: 10.1186/s12916-023-02989-2

PMCID:: PMC10403950

Abstract Article PDF–17M

Select item 1031789513.

RELA governs a network of islet-specific metabolic genes necessary for beta cell function

Nathan W. Zammit, Ying Ying Wong, Stacey N. Walters, Joanna Warren, Simon C. Barry, Shane T. Grey

Diabetologia. 2023; 66(8): 1516–1531. Published online 2023 Jun 14. doi: 10.1007/s00125-023-05931-6

PMCID:: PMC10317895

Abstract Article PDF–3.0M

Select item 1024241114.

Human RELA dominant-negative mutations underlie type I interferonopathy with autoinflammation and autoimmunity

Kunihiko Moriya, Tomohiro Nakano, Yoshitaka Honda, Miyuki Tsumura, Masato Ogishi, Motoshi Sonoda, Masahiko Nishitani-Isa, Takashi Uchida, Mohamed Hbibi, Yoko Mizoguchi, Masataka Ishimura, Kazushi Izawa, Takaki Asano, Fumihiko Kakuta, Daiki Abukawa, Darawan Rinchai, Peng Zhang, Naotomo Kambe, Aziz Bousfiha, Takahiro Yasumi, Bertrand Boisson, Anne Puel, Jean-Laurent Casanova, Ryuta Nishikomori, Shouichi Ohga, Satoshi Okada, Yoji Sasahara, Shigeo Kure

J Exp Med. 2023 Sep 4; 220(9): e20212276. Published online 2023 Jun 5. doi: 10.1084/jem.20212276

PMCID:: PMC10242411

Abstract Article PDF–6.4M

Select item 1023742215.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1023626316.

miR‑27a‑3p upregulation by p65 facilitates cervical tumorigenesis by increasing TAB3 expression and is involved in the positive feedback loop of NF‑κB signaling

Min Li, Zixuan Gao, Shuo Wang, Yungang Zhao, Hong Xie

Oncol Rep. 2023 Jul; 50(1): 132. Published online 2023 May 10. doi: 10.3892/or.2023.8569

PMCID:: PMC10236263

Abstract Article PDF–8.3M

Select item 1017839617.

NF-κB Signaling Modulates miR-452-5p and miR-335-5p Expression to Functionally Decrease Epithelial Ovarian Cancer Progression in Tumor-Initiating Cells

Rahul D. Kamdar, Brittney S. Harrington, Emma Attar, Soumya Korrapati, Jyoti Shetty, Yongmei Zhao, Bao Tran, Nathan Wong, Carrie D. House, Christina M. Annunziata

Int J Mol Sci. 2023 May; 24(9): 7826. Published online 2023 Apr 25. doi: 10.3390/ijms24097826

PMCID:: PMC10178396

Abstract Article PDF–2.1M

Select item 1017378218.

Epstein–Barr virus envelope glycoprotein 110 inhibits NF-κB activation by interacting with NF-κB subunit p65

Mingsheng Cai, Bin Xiao, Yuanfang Wang, Kezhen Wang, Wenqi Luo, Jiangqin Fu, Shuai Wang, Shenyu Deng, Bolin Li, Lan Gong, Jiayi Zhong, Li Hu, Lingxia Pan, Liding Wang, Yintao Liu, Chen Huang, Xiaoqing Li, Qiyuan Zeng, Haoran Kang, Linhai Li, Jie Zan, Tao Peng, Haidi Yang, Meili Li

J Biol Chem. 2023 May; 299(5): 104613. Published online 2023 Mar 16. doi: 10.1016/j.jbc.2023.104613

PMCID:: PMC10173782

Abstract Article PDF–4.2M

Select item 1013009019.

Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development

Mingyu Lee, Yi-Sook Kim, Suha Lim, Seung-Hyun Shin, Iljin Kim, Jiyoung Kim, Min Choi, Jung Ho Kim, Seong-Joon Koh, Jong-Wan Park, Hyun-Woo Shin

Nat Commun. 2023; 14: 2363. Published online 2023 Apr 25. doi: 10.1038/s41467-023-38080-w

PMCID:: PMC10130090

Abstract Article PDF–8.4M

Select item 1001148020.

Case report: Novel variants in RELA associated with familial Behcet’s-like disease

Jason W. An, Pallavi Pimpale-Chavan, Deborah L. Stone, Marcia Bandeira, Fatma Dedeoglu, Jeffrey Lo, John Bohnsack, Sofia Rosenzweig, Oskar Schnappauf, Dilan Dissanayake, Linda T. Hiraki, Daniel L. Kastner, Christina Pelajo, Ronald M. Laxer, Ivona Aksentijevich

Front Immunol. 2023; 14: 1127085. Published online 2023 Feb 28. doi: 10.3389/fimmu.2023.1127085

PMCID:: PMC10011480

Abstract Article PDF–2.6M

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