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Items: 1 to 20 of 141

1.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
2.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
3.
The 3’ UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study
Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Glenn P. Lobo, Saleh A. Al-Obeidan
PLoS One. 2023; 18(4): e0284852. Published online 2023 Apr 26. doi: 10.1371/journal.pone.0284852
PMCID:
PMC10132650
AbstractArticlePDF–1.0M
4.
Downregulation of DROSHA: Could It Affect miRNA Biogenesis in Endometriotic Menstrual Blood Mesenchymal Stem Cells?
Ana Clara Lagazzi Cressoni, Letícia B. C. Penariol, Cristiana Carolina Padovan, Maristela D. Orellana, Júlio Cesar Rosa-e-Silva, Omero Benedicto Poli-Neto, Rui Alberto Ferriani, Cláudia Cristina Paro de Paz, Juliana Meola
Int J Mol Sci. 2023 Mar; 24(6): 5963. Published online 2023 Mar 22. doi: 10.3390/ijms24065963
PMCID:
PMC10057010
AbstractArticlePDF–686K
5.
The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8
Yanping Li, Timothy S. Carey, Catherine H. Feng, Hong-Ming Zhu, Xiao-Xin Sun, Mu-Shui Dai
Cancer Res Commun. 2023 Mar; 3(3): 459–470. Published online 2023 Mar 20. doi: 10.1158/2767-9764.CRC-22-0344
PMCID:
PMC10026737
AbstractArticlePDF–11M
6.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
7.
Immunohistochemical expression of Drosha is reduced in eutopic and ectopic endometrium of women with adenomyosis
I. Ormenezi, A. Ribeiro-Silva, J.C. Rosa-e-Silva, J. Meola, F.J. Candido-dos-Reis, O.B. Poli-Neto
Braz J Med Biol Res. 2022; 55: e12375. Published online 2022 Dec 12. doi: 10.1590/1414-431X2022e12375
PMCID:
PMC9744411
AbstractArticlePDF–785K
8.
The Drosha-Independent MicroRNA6778-5p/GSK3β Axis Mediates the Proliferation of Gastric Cancer Cells
Mingjun Ren, Li Xing, Wanping Wang, Wanying Bi, Wanjun Wu, Gui Jiang, Weiji Wang, Xingdong Liang, Manran Liu, Shifu Tang
Comput Intell Neurosci. 2022; 2022: 5932512. Published online 2022 Sep 30. doi: 10.1155/2022/5932512
PMCID:
PMC9546646
AbstractArticlePDF–594K
9.
The microRNA processor DROSHA is a candidate gene for a severe progressive neurological disorder
Scott Barish, Mumine Senturk, Kelly Schoch, Amanda L Minogue, Diego Lopergolo, Chiara Fallerini, Jake Harland, Jacob H Seemann, Nicholas Stong, Peter G Kranz, Sujay Kansagra, Mohamad A Mikati, Joan Jasien, Mays El-Dairi, Paolo Galluzzi, Undiagnosed Diseases Network , Francesca Ariani, Alessandra Renieri, Francesca Mari, Michael F Wangler, Swathi Arur, Yong-Hui Jiang, Shinya Yamamoto, Vandana Shashi, Hugo J Bellen
Hum Mol Genet. 2022 Sep 1; 31(17): 2934–2950. Published online 2022 Apr 11. doi: 10.1093/hmg/ddac085
PMCID:
PMC9433733
AbstractArticlePDF–1.7M
10.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
11.
The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis
Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi
Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y
PMCID:
PMC9343455
AbstractArticlePDF–3.7M
12.
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7
PMCID:
PMC9290241
AbstractArticlePDF–8.2M
13.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
14.
Evaluating the Effect of 3′-UTR Variants in DICER1 and DROSHA on Their Tissue-Specific Expression by miRNA Target Prediction
Dmitrii S. Bug, Artem V. Tishkov, Ivan S. Moiseev, Natalia V. Petukhova
Curr Issues Mol Biol. 2021 Sep; 43(2): 605–617. Published online 2021 Jul 6. doi: 10.3390/cimb43020044
PMCID:
PMC8929110
AbstractArticlePDF–1.2M
15.
Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a
Christopher J. Fields, Lu Li, Nicholas M. Hiers, Tianqi Li, Peike Sheng, Taha Huda, Jixiu Shan, Lauren Gay, Tongjun Gu, Jiang Bian, Michael S. Kilberg, Rolf Renne, Mingyi Xie
PLoS Genet. 2021 Dec; 17(12): e1009934. Published online 2021 Dec 16. doi: 10.1371/journal.pgen.1009934
PMCID:
PMC8675727
AbstractArticlePDF–1.5M
16.
p38 MAPK‐mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta‐induced neuronal stress in Alzheimer's disease
Haidong Xu, Xiaolei Liu, Wenming Li, Ye Xi, Peng Su, Bo Meng, Xiaoyun Shao, Beisha Tang, Qian Yang, Zixu Mao
Aging Cell. 2021 Oct; 20(10): e13434. Published online 2021 Sep 16. doi: 10.1111/acel.13434
PMCID:
PMC8521488
AbstractArticlePDF–2.5M
17.
Towards Understanding the Pathogenicity of DROSHA Mutations in Oncohematology
Dmitrii S. Bug, Artem V. Tishkov, Ivan S. Moiseev, Yuri B. Porozov, Natalia V. Petukhova
Cells. 2021 Sep; 10(9): 2357. Published online 2021 Sep 8. doi: 10.3390/cells10092357
PMCID:
PMC8471307
AbstractArticlePDF–1.9M
18.
Impact of DICER1 and DROSHA on the Angiogenic Capacity of Human Endothelial Cells
Heike Braun, Michael Hauke, Anne Ripperger, Christian Ihling, Matthew Fuszard, Robert Eckenstaler, Ralf A. Benndorf
Int J Mol Sci. 2021 Sep; 22(18): 9855. Published online 2021 Sep 12. doi: 10.3390/ijms22189855
PMCID:
PMC8471234
AbstractArticlePDF–2.7M
19.
Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome
Jérémy A. Ferreira Barbosa, Samantha Sparapani, Jonathan Boulais, Robert Lodge, Éric A. Cohen
J Virol. 2021 Aug; 95(15): e00971-20. Prepublished online 2021 May 19. Published online 2021 Jul 12. doi: 10.1128/JVI.00971-20
PMCID:
PMC8274603
AbstractArticlePDF–4.2M
20.
Tissue-specific and transcription-dependent mechanisms regulate primary microRNA processing efficiency of the human chromosome 19 MicroRNA cluster
Ábel Fóthi, Orsolya Biró, Zsuzsa Erdei, Ágota Apáti, Tamás I. Orbán
RNA Biol. 2021; 18(8): 1170–1180. Published online 2020 Oct 23. doi: 10.1080/15476286.2020.1836457
PMCID:
PMC8244754
AbstractArticlePDF–4.3M

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