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Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75336562.

Hair cell α9α10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products

Shenyan Gu, Daniel Knowland, Jose A. Matta, Min L. O’Carroll, Weston B. Davini, Madhurima Dhara, Hae-Jin Kweon, David S. Bredt

Proc Natl Acad Sci U S A. 2020 Sep 29; 117(39): 24534–24544. Published online 2020 Sep 14. doi: 10.1073/pnas.2013762117

PMCID:: PMC7533656

Abstract Article PDF–2.4M

Select item 59802263.

α9‐containing nicotinic acetylcholine receptors and the modulation of pain

Arik J Hone, Denis Servent, J Michael McIntosh

Br J Pharmacol. 2018 Jun; 175(11): 1915–1927. Published online 2017 Jul 30. doi: 10.1111/bph.13931

PMCID:: PMC5980226

Abstract Article PDF–451K

Select item 55316114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 53475375.

Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

Haylie K. Romero, Sean B. Christensen, Lorenzo Di Cesare Mannelli, Joanna Gajewiak, Renuka Ramachandra, Keith S. Elmslie, Douglas E. Vetter, Carla Ghelardini, Shawn P. Iadonato, Jose L. Mercado, Baldomera M. Olivera, J. Michael McIntosh

Proc Natl Acad Sci U S A. 2017 Mar 7; 114(10): E1825–E1832. Published online 2017 Feb 21. doi: 10.1073/pnas.1621433114

PMCID:: PMC5347537

Abstract Article PDF–1.2M

Select item 49238966.

Phosphocholine – an agonist of metabotropic but not of ionotropic functions of α9-containing nicotinic acetylcholine receptors

K. Richter, V. Mathes, M. Fronius, M. Althaus, A. Hecker, G. Krasteva-Christ, W. Padberg, A. J. Hone, J. M. McIntosh, A. Zakrzewicz, V. Grau

Sci Rep. 2016; 6: 28660. Published online 2016 Jun 28. doi: 10.1038/srep28660

PMCID:: PMC4923896

Abstract Article PDF–1.1M

Select item 46172117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 44524588.

The Contribution of Rare and Common Variants in 30 Genes to Risk Nicotine Dependence

Jiekun Yang, Shaolin Wang, Zhongli Yang, Colin A. Hodgkinson, Polina Iarikova, Jennie Z. Ma, Thomas J. Payne, David Goldman, Ming D. Li

Mol Psychiatry. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Mol Psychiatry. 2015 Nov; 20(11): 1467–1478. Published online 2014 Dec 2. doi: 10.1038/mp.2014.156

PMCID:: PMC4452458

Abstract Article PDF–753K

Select item 41367999.

Genome-Wide Association Studies and Heritability Estimates of Body Mass Index Related Phenotypes in Bangladeshi Adults

Molly Scannell Bryan, Maria Argos, Brandon Pierce, Lin Tong, Muhammad Rakibuz-Zaman, Alauddin Ahmed, Mahfuzar Rahman, Tariqul Islam, Muhammad Yunus, Faruque Parvez, Shantanu Roy, Farzana Jasmine, John A. Baron, Muhammad G. Kibriya, Habibul Ahsan

PLoS One. 2014; 9(8): e105062. Published online 2014 Aug 18. doi: 10.1371/journal.pone.0105062

PMCID:: PMC4136799

Abstract Article PDF–692K

Select item 343365010.

Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA

Layla Azam, J Michael McIntosh

J Neurochem. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: J Neurochem. 2012 Sep; 122(6): 1137–1144. Published online 2012 Aug 3. doi: 10.1111/j.1471-4159.2012.07867.x

PMCID:: PMC3433650

Abstract Article PDF–1.6M

Select item 334150111.

New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer

Anna Chikova, Hans-Ulrich Bernard, Igor B. Shchepotin, Sergei A. Grando

Life Sci. Author manuscript; available in PMC 2013 Nov 27.

Published in final edited form as: Life Sci. 2012 Nov 27; 91(21-22): 1103–1108. Published online 2012 Jan 17. doi: 10.1016/j.lfs.2011.12.023

PMCID:: PMC3341501

Abstract Article PDF–302K

Select item 322071912.

Naturally Occurring Variants of Human Α9 Nicotinic Receptor Differentially Affect Bronchial Cell Proliferation and Transformation

Anna Chikova, Sergei A. Grando

PLoS One. 2011; 6(11): e27978. Published online 2011 Nov 18. doi: 10.1371/journal.pone.0027978

PMCID:: PMC3220719

Abstract Article PDF–411K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 298649914.

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis

Anna C Need, Richard SE Keefe, Dongliang Ge, Iris Grossman, Sam Dickson, Joseph P McEvoy, David B Goldstein

Eur J Hum Genet. 2009 Jul; 17(7): 946–957. Published online 2009 Jan 21. doi: 10.1038/ejhg.2008.264

PMCID:: PMC2986499

Abstract Article PDF–172K

Select item 296729715.

A large-scale candidate-gene association study of age at menarche and age at natural menopause

Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter

Hum Genet. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4

PMCID:: PMC2967297

Abstract Article PDF–84K

Select item 269330716.

Multiple Distinct Risk Loci for Nicotine Dependence Identified by Dense Coverage of the Complete Family of Nicotinic Receptor Subunit (CHRN) Genes

Nancy L. Saccone, Scott F. Saccone, Anthony L. Hinrichs, Jerry A. Stitzel, Weimin Duan, Michele L. Pergadia, Arpana Agrawal, Naomi Breslau, Richard A. Grucza, Dorothy Hatsukami, Eric O. Johnson, Pamela A. F. Madden, Gary E. Swan, Jen C. Wang, Alison M. Goate, John P. Rice, Laura J. Bierut

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2010 Jun 5.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 5; 150B(4): 453–466. doi: 10.1002/ajmg.b.30828

PMCID:: PMC2693307

Abstract Article PDF–1.6M

Select item 268298317.

CENTRAL ROLE OF α9 ACETYLCHOLINE RECEPTOR IN COORDINATING KERATINOCYTE ADHESION AND MOTILITY AT THE INITIATION OF EPITHELIALIZATION

Alex I. Chernyavsky, Juan Arredondo, Douglas E. Vetter, Sergei A. Grando

Exp Cell Res. Author manuscript; available in PMC 2009 May 15.

Published in final edited form as: Exp Cell Res. 2007 Oct 1; 313(16): 3542–3555. Published online 2007 Jul 20. doi: 10.1016/j.yexcr.2007.07.011

PMCID:: PMC2682983

Abstract Article PDF–2.7M

Select item 257647718.

No Evidence for Association between 19 Cholinergic Genes and Bipolar Disorder

Jiajun Shi, Eiji Hattori, Hongwei Zou, Judith A. Badner, Susan L. Christian, Elliot S. Gershon, Chunyu Liu

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2008 Oct 30.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2007 Sep 5; 144B(6): 715–723. doi: 10.1002/ajmg.b.30417

PMCID:: PMC2576477

Abstract Article PDF–319K

Select item 248061819.

Muscle-like Nicotinic Receptor Accessory Molecules In Sensory Hair Cells of the Inner Ear

Abdullah A. Osman, Angela D. Schrader, Aubrey J. Hawkes, Omar Akil, Adam Bergeron, Lawrence R. Lustig, Dwayne D. Simmons

Mol Cell Neurosci. Author manuscript; available in PMC 2009 Jun 1.

Published in final edited form as: Mol Cell Neurosci. 2008 Jun; 38(2): 153–169. Published online 2008 Mar 4. doi: 10.1016/j.mcn.2008.02.008

PMCID:: PMC2480618

Abstract Article PDF–2.8M

Select item 189911120.

Distinct class of putative “non-conserved” promoters in humans: Comparative studies of alternative promoters of human and mouse genes

Katsuki Tsuritani, Takuma Irie, Riu Yamashita, Yuta Sakakibara, Hiroyuki Wakaguri, Akinori Kanai, Junko Mizushima-Sugano, Sumio Sugano, Kenta Nakai, Yutaka Suzuki

Genome Res. 2007 Jul; 17(7): 1005–1014. doi: 10.1101/gr.6030107

PMCID:: PMC1899111

Abstract Article PDF–757K

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Interferon-gamma effect on peripheral blood monocyte-derived dendritic cells
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Saracatinib-sensitive versus -resistant, PIK3CA mutant colorectal cancer xenogra...
Saracatinib-sensitive versus -resistant, PIK3CA mutant colorectal cancer xenografts
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