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Items: 1 to 20 of 39

1.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
4.
Comprehensive analysis of macrophage-related multigene signature in the tumor microenvironment of head and neck squamous cancer
Bo Lin, Hao Li, Tianwen Zhang, Xin Ye, Hongyu Yang, Yuehong Shen
Aging (Albany NY) 2021 Feb 28; 13(4): 5718–5747. Published online 2021 Feb 11. doi: 10.18632/aging.202499
PMCID:
PMC7950226
AbstractArticlePDF–2.9M
5.
Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets
Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge
Mol Cell. Author manuscript; available in PMC 2019 Dec 4.
Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008
PMCID:
PMC6892393
AbstractArticlePDF–1.7M
6.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
7.
HES1 is a novel interactor of the Fanconi anemia core complex
Cédric S. Tremblay, Feng F. Huang, Ouassila Habi, Caroline C. Huard, Chantal Godin, Georges Lévesque, Madeleine Carreau
Blood. Author manuscript; available in PMC 2016 Dec 13.
Published in final edited form as: Blood. 2008 Sep 1; 112(5): 2062–2070. Published online 2008 Jun 11. doi: 10.1182/blood-2008-04-152710
PMCID:
PMC5154739
AbstractArticlePDF–1.1M
8.
Modularized Functions of the Fanconi Anemia Core Complex
Yaling Huang, Justin WC Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li
Cell Rep. Author manuscript; available in PMC 2015 Jun 26.
Published in final edited form as: Cell Rep. 2014 Jun 26; 7(6): 1849–1857. Published online 2014 Jun 5. doi: 10.1016/j.celrep.2014.04.029
PMCID:
PMC4157997
AbstractArticlePDF–1.4M
9.
The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability
David Fox, 3rd, Zhijiang Yan, Chen Ling, Ye Zhao, Duck-Yeon Lee, Tatsuo Fukagawa, Wei Yang, Weidong Wang
Cell Res. 2014 May; 24(5): 560–575. Published online 2014 Apr 4. doi: 10.1038/cr.2014.42
PMCID:
PMC4011343
AbstractArticlePDF–1.2M
10.
The Carboxyl Terminus of FANCE Recruits FANCD2 to the Fanconi Anemia (FA) E3 Ligase Complex to Promote the FA DNA Repair Pathway
David Polito, Scott Cukras, Xiaozhe Wang, Paige Spence, Lisa Moreau, Alan D. D'Andrea, Younghoon Kee
J Biol Chem. 2014 Mar 7; 289(10): 7003–7010. Published online 2014 Jan 22. doi: 10.1074/jbc.M113.533976
PMCID:
PMC3945361
AbstractArticlePDF–1.3M
11.
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression
Caroline C. Huard, Cédric S. Tremblay, Audrey Magron, Georges Lévesque, Madeleine Carreau
Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6): 2152–2157. Published online 2014 Jan 27. doi: 10.1073/pnas.1314226111
PMCID:
PMC3926087
AbstractArticlePDF–1.1M
12.
Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function
Dana B. Hancock, María Soler Artigas, Sina A. Gharib, Amanda Henry, Ani Manichaikul, Adaikalavan Ramasamy, Daan W. Loth, Medea Imboden, Beate Koch, Wendy L. McArdle, Albert V. Smith, Joanna Smolonska, Akshay Sood, Wenbo Tang, Jemma B. Wilk, Guangju Zhai, Jing Hua Zhao, Hugues Aschard, Kristin M. Burkart, Ivan Curjuric, Mark Eijgelsheim, Paul Elliott, Xiangjun Gu, Tamara B. Harris, Christer Janson, Georg Homuth, Pirro G. Hysi, Jason Z. Liu, Laura R. Loehr, Kurt Lohman, Ruth J. F. Loos, Alisa K. Manning, Kristin D. Marciante, Ma'en Obeidat, Dirkje S. Postma, Melinda C. Aldrich, Guy G. Brusselle, Ting-hsu Chen, Gudny Eiriksdottir, Nora Franceschini, Joachim Heinrich, Jerome I. Rotter, Cisca Wijmenga, O. Dale Williams, Amy R. Bentley, Albert Hofman, Cathy C. Laurie, Thomas Lumley, Alanna C. Morrison, Bonnie R. Joubert, Fernando Rivadeneira, David J. Couper, Stephen B. Kritchevsky, Yongmei Liu, Matthias Wjst, Louise V. Wain, Judith M. Vonk, André G. Uitterlinden, Thierry Rochat, Stephen S. Rich, Bruce M. Psaty, George T. O'Connor, Kari E. North, Daniel B. Mirel, Bernd Meibohm, Lenore J. Launer, Kay-Tee Khaw, Anna-Liisa Hartikainen, Christopher J. Hammond, Sven Gläser, Jonathan Marchini, Peter Kraft, Nicholas J. Wareham, Henry Völzke, Bruno H. C. Stricker, Timothy D. Spector, Nicole M. Probst-Hensch, Deborah Jarvis, Marjo-Riitta Jarvelin, Susan R. Heckbert, Vilmundur Gudnason, H. Marike Boezen, R. Graham Barr, Patricia A. Cassano, David P. Strachan, Myriam Fornage, Ian P. Hall, Josée Dupuis, Martin D. Tobin, Stephanie J. London
PLoS Genet. 2012 Dec; 8(12): e1003098. Published online 2012 Dec 20. doi: 10.1371/journal.pgen.1003098
PMCID:
PMC3527213
AbstractArticlePDF–417K
13.
A ubiquitin-binding protein FAAP20 links RNF8-mediated ubiquitination to the Fanconi anemia DNA Repair network
Zhijiang Yan, Rong Guo, Manikandan Paramasivam, Weiping Shen, Chen Ling, David Fox, III, Yucai Wang, Anneke B. Oostra, Julia Kuehl, Duck-Yeon Lee, Minoru Takata, Maureen E. Hoatlin, Detlev Schindler, Hans Joenje, Johan P. de Winter, Lei Li, Michael M. Seidman, Weidong Wang
Mol Cell. Author manuscript; available in PMC 2013 Jul 13.
Published in final edited form as: Mol Cell. 2012 Jul 13; 47(1): 61–75. Published online 2012 Jun 14. doi: 10.1016/j.molcel.2012.05.026
PMCID:
PMC3398238
AbstractArticlePDF–4.8M
14.
FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway
Abdullah Mahmood Ali, Arun Pradhan, Thiyam Ramsingh Singh, Changhu Du, Jie Li, Kebola Wahengbam, Elke Grassman, Arleen D. Auerbach, Qishen Pang, Amom Ruhikanta Meetei
Blood. 2012 Apr 5; 119(14): 3285–3294. Prepublished online 2012 Feb 17. doi: 10.1182/blood-2011-10-385963
PMCID:
PMC3321854
AbstractArticle
15.
Regulation of Rev1 by the Fanconi Anemia Core Complex
Hyungjin Kim, Kailin Yang, Donniphat Dejsuphong, Alan D. D’Andrea
Nat Struct Mol Biol. Author manuscript; available in PMC 2012 Aug 1.
Published in final edited form as: Nat Struct Mol Biol. 2012 Feb; 19(2): 164–170. Published online 2012 Jan 22. doi: 10.1038/nsmb.2222
PMCID:
PMC3280818
AbstractArticlePDF–1.2M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk
Genevieve M. Monsees, Peter Kraft, Stephen J. Chanock, David J. Hunter, Jiali Han
Breast Cancer Res Treat. Author manuscript; available in PMC 2012 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2011 Jan; 125(1): 207–214. Published online 2010 May 23. doi: 10.1007/s10549-010-0947-3
PMCID:
PMC2997162
AbstractArticlePDF–416K
18.
Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins
James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters
Science. Author manuscript; available in PMC 2010 Nov 22.
Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348
PMCID:
PMC2989461
AbstractArticlePDF–2.2M
19.
RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network
Liyi Geng, Catherine J. Huntoon, Larry M. Karnitz
J Cell Biol. 2010 Oct 18; 191(2): 249–257. doi: 10.1083/jcb.201005101
PMCID:
PMC2958487
AbstractArticlePDF–3.9M
20.
The Fanconi anemia pathway promotes replication-dependent DNA interstrand crosslink repair
Puck Knipscheer, Markus Räschle, Agata Smogorzewska, Milica Enoiu, The Vinh Ho, Orlando D. Schärer, Stephen J. Elledge, Johannes C. Walter
Science. Author manuscript; available in PMC 2010 Jul 26.
Published in final edited form as: Science. 2009 Dec 18; 326(5960): 1698–1701. Published online 2009 Nov 12. doi: 10.1126/science.1182372
PMCID:
PMC2909596
AbstractArticlePDF–1.9M

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