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Items: 1 to 20 of 78

1.
Comparison of the Activation Kinetics of the M3 Acetylcholine Receptor and a Constitutively Active Mutant Receptor in Living Cells
Carsten Hoffmann, Susanne Nuber, Ulrike Zabel, Nicole Ziegler, Christiane Winkler, Peter Hein, Catherine H. Berlot, Moritz Bünemann, Martin J. Lohse
Mol Pharmacol. 2012 Aug; 82(2): 236–245. doi: 10.1124/mol.112.077578
PMCID:
PMC11037427
AbstractArticlePDF–950K
2.
Associations of genetic variations in the M3 receptor with salt sensitivity, longitudinal changes in blood pressure and the incidence of hypertension in Chinese adults
Xi Zhang, Shi Yao, Peng Bao, Mingfei Du, Guilin Hu, Chao Chu, Dan Wang, Chen Chen, Qiong Ma, Hao Jia, Yue Sun, Yu Yan, Yueyuan Liao, Zejiaxin Niu, Ziyue Man, Lan Wang, Weihua Gao, Hao Li, Jie Zhang, Wenjing Luo, Xin Wang, Yang Wang, Jianjun Mu
J Clin Hypertens (Greenwich) 2024 Jan; 26(1): 36–46. Published online 2023 Nov 27. doi: 10.1111/jch.14753
PMCID:
PMC10795080
AbstractArticlePDF–222K
3.
Muscarinic Acetylcholine Receptor M3 Expression and Survival in Human Colorectal Carcinoma—An Unexpected Correlation to Guide Future Treatment?
Leonard A. Lobbes, Marcel A. Schütze, Raoul Droeser, Marco Arndt, Ioannis Pozios, Johannes C. Lauscher, Nina A. Hering, Benjamin Weixler
Int J Mol Sci. 2023 May; 24(9): 8198. Published online 2023 May 3. doi: 10.3390/ijms24098198
PMCID:
PMC10179005
AbstractArticlePDF–1.1M
4.
CHRM3-Associated miRNAs May Play a Role in Bile Acid-Induced Proliferation of H508 Colon Cancer Cells
Çağdaş Aktan, Fatih Tekin, Nevin Oruç, Ömer Özütemiz
Turk J Gastroenterol. 2023 Mar; 34(3): 298–307. Published online 2023 Mar 1. doi: 10.5152/tjg.2022.22605
PMCID:
PMC10152154
AbstractArticlePDF–1.2M
5.
Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands
Yiyu Wang, Jörg Scheffel, Carolina Ayala Vera, Wei Liu, Dorothee Günzel, Dorothea Terhorst-Molawi, Marcus Maurer, Sabine Altrichter
Front Immunol. 2022; 13: 955161. Published online 2022 Jul 29. doi: 10.3389/fimmu.2022.955161
PMCID:
PMC9373796
AbstractArticlePDF–3.8M
6.
Expression of M3 muscarinic acetylcholine receptors in gastric cancer
Alina Maria Mehedinţeanu, Cecil Sorin Mirea, Puiu Olivian Stovicek, Michael Schenker, Marius Ionuţ Stancu, Ana-Maria Ciurea, Liliana Streba, Anca-Maria Istrate-Ofiţeru, Teodor-Nicuşor Sas, Cristin Constantin Vere
Rom J Morphol Embryol. 2021 Oct-Dec; 62(4): 1001–1010. Published online 2022 May 24. doi: 10.47162/RJME.62.4.12
PMCID:
PMC9289715
AbstractArticlePDF–4.3M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
CHRM2 but not CHRM1 or CHRM3 polymorphisms are associated with asthma susceptibility in Mexican patients
Silvia Jiménez-Morales, Juan Luis Jiménez-Ruíz, Blanca Estela Del Río-Navarro, Efraín Navarro-Olivos, Guillermo Escamilla-Guerrero, Ram Savan, Michael Dean, Lorena Orozco
Mol Biol Rep. Author manuscript; available in PMC 2020 Nov 17.
Published in final edited form as: Mol Biol Rep. 2014; 41(4): 2109–2117. Published online 2014 Jan 16. doi: 10.1007/s11033-014-3060-6
PMCID:
PMC7670879
AbstractArticlePDF–468K
9.
M3 muscarinic acetylcholine receptor–reactive Th17 cells in primary Sjögren’s syndrome
Saori Abe, Hiroto Tsuboi, Hanae Kudo, Hiromitsu Asashima, Yuko Ono, Fumika Honda, Hiroyuki Takahashi, Mizuki Yagishita, Shinya Hagiwara, Yuya Kondo, Isao Matsumoto, Takayuki Sumida
JCI Insight. 2020 Aug 6; 5(15): e135982. Published online 2020 Aug 6. doi: 10.1172/jci.insight.135982
PMCID:
PMC7455086
AbstractArticlePDF–13M
10.
Muscarinic receptors promote castration resistant growth of prostate cancer through a FAK-YAP signaling axis
Yusuke Goto, Toshinori Ando, Hiroki Izumi, Xiaodong Feng, Nadia Arang, Mara Gilardi, Zhiyong Wang, Kazuyo Ando, J. Silvio Gutkind
Oncogene. Author manuscript; available in PMC 2020 Sep 23.
Published in final edited form as: Oncogene. 2020 May; 39(20): 4014–4027. Published online 2020 Mar 23. doi: 10.1038/s41388-020-1272-x
PMCID:
PMC7428076
AbstractArticlePDF–1.0M
11.
A homozygous missense variant in CHRM3 associated with familial urinary bladder disease
Glenda M. Beaman, Gabriella Galatà, Keng W. Teik, Jill E. Urquhart, Ali Aishah, James O'Sullivan, Sanjeev S. Bhaskar, Katherine A. Wood, Huw B. Thomas, Raymond T. O'Keefe, Adrian S. Woolf, Helen M. Stuart, William G. Newman
Clin Genet. 2019 Dec; 96(6): 515–520. Published online 2019 Sep 11. doi: 10.1111/cge.13631
PMCID:
PMC6899476
AbstractArticlePDF–1.3M
12.
A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans
Zhongshan Cheng, Chureerat Phokaew, Yi-Ling Chou, Dongbing Lai, Jacquelyn L. Meyers, Arpana Agrawal, Lindsay A. Farrer, Henry R. Kranzler, Joel Gelernter
Transl Psychiatry. 2019; 9: 309. Published online 2019 Nov 18. doi: 10.1038/s41398-019-0639-7
PMCID:
PMC6861240
AbstractArticlePDF–767K
13.
M3-subtype muscarinic receptor activation stimulates intracellular calcium oscillations and aldosterone production in human adrenocortical HAC15 cells
Latha M. Malaiyandi, Harsh Sharthiya, Nuntida Surachaicharn, Yara Shams, Mohammad Arshad, Chad Schupbach, Phillip G. Kopf, Kirk E. Dineley
Mol Cell Endocrinol. Author manuscript; available in PMC 2019 Dec 15.
Published in final edited form as: Mol Cell Endocrinol. 2018 Dec 15; 478: 1–9. Published online 2018 Jun 28. doi: 10.1016/j.mce.2018.06.016
PMCID:
PMC6193837
AbstractArticlePDF–412K
14.
Muscarinic Receptor M3R Signaling Prevents Efficient Remyelination by Human and Mouse Oligodendrocyte Progenitor Cells
R. Ross Welliver, Jessie J. Polanco, Richard A. Seidman, Anjali K. Sinha, Melanie A. O'Bara, Zainab M. Khaku, Diara A. Santiago González, Akiko Nishiyama, Jurgen Wess, M. Laura Feltri, Pablo M. Paez, Fraser J. Sim
J Neurosci. 2018 Aug 1; 38(31): 6921–6932. doi: 10.1523/JNEUROSCI.1862-17.2018
PMCID:
PMC6070663
AbstractArticlePDF–3.8M
15.
Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells
Anan H. Said, Shien Hu, Ameer Abutaleb, Tonya Watkins, Kunrong Cheng, Ahmed Chahdi, Panjamurthy Kuppusamy, Neeraj Saxena, Guofeng Xie, Jean-Pierre Raufman
Biochem J. Author manuscript; available in PMC 2018 Feb 20.
Published in final edited form as: Biochem J. 2017 Feb 20; 474(5): 647–665. Published online 2017 Feb 20. doi: 10.1042/BCJ20160704
PMCID:
PMC5650067
AbstractArticlePDF–1.6M
16.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
17.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
18.
Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis
Kunrong Cheng, Aaron C. Shang, Cinthia B. Drachenberg, Min Zhan, Jean-Pierre Raufman
Oncotarget. 2017 Mar 28; 8(13): 21106–21114. Published online 2017 Feb 18. doi: 10.18632/oncotarget.15500
PMCID:
PMC5400569
AbstractArticlePDF–4.3M
19.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
20.
Regulation of molecular clock oscillations and phagocytic activity via muscarinic Ca2+ signaling in human retinal pigment epithelial cells
Rina Ikarashi, Honami Akechi, Yuzuki Kanda, Alsawaf Ahmad, Kouhei Takeuchi, Eri Morioka, Takashi Sugiyama, Takashi Ebisawa, Masaaki Ikeda, Masayuki Ikeda
Sci Rep. 2017; 7: 44175. Published online 2017 Mar 9. doi: 10.1038/srep44175
PMCID:
PMC5343479
AbstractArticlePDF–2.0M

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