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Items: 1 to 20 of 128

1.
Down-Regulation of CYP3A4 by the KCa1.1 Inhibition Is Responsible for Overcoming Resistance to Doxorubicin in Cancer Spheroid Models
Susumu Ohya, Junko Kajikuri, Hiroaki Kito, Miki Matsui
Int J Mol Sci. 2023 Nov; 24(21): 15672. Published online 2023 Oct 27. doi: 10.3390/ijms242115672
PMCID:
PMC10648085
AbstractArticlePDF–5.7M
2.
Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models
Ria L. Dinsdale, Cooper E. Roache, Andrea L. Meredith
J Gen Physiol. 2023 Nov 6; 155(11): e202313357. Published online 2023 Sep 20. doi: 10.1085/jgp.202313357
PMCID:
PMC10510740
AbstractArticlePDF–2.9M
3.
外周血中KCNMA1基因甲基化水平与肺癌的发生和发展相关
臧 紫珊, 乔 荣, 朱 强, 周 夏婕, 顾 万建, 韩 宝惠, 杨 蓉西
Nan Fang Yi Ke Da Xue Xue Bao. 2023 Mar 20; 43(3): 349–359. Chinese. doi: 10.12122/j.issn.1673-4254.2023.03.03
PMCID:
PMC10122738
AbstractArticlePDF–1.1M
4.
KCa1.1 K+ Channel Inhibition Overcomes Resistance to Antiandrogens and Doxorubicin in a Human Prostate Cancer LNCaP Spheroid Model
Susumu Ohya, Junko Kajikuri, Kyoko Endo, Hiroaki Kito, Miki Matsui
Int J Mol Sci. 2021 Dec; 22(24): 13553. Published online 2021 Dec 17. doi: 10.3390/ijms222413553
PMCID:
PMC8706449
AbstractArticlePDF–3.7M
5.
Two novel presentations of KCNMA1‐related pathology––Expanding the clinical phenotype of a rare channelopathy
Jotte Rodrigues Bento, Candice Feben, Marlies Kempers, Maartje van Rij, Mallory Woiski, Koenraad Devriendt, Luc De Catte, Marcella Baldewijns, Maaike Alaerts, Josephina Meester, Aline Verstraeten, Willy Hendson, Bart Loeys
Mol Genet Genomic Med. 2021 Oct; 9(10): e1797. Published online 2021 Sep 9. doi: 10.1002/mgg3.1797
PMCID:
PMC8580096
AbstractArticlePDF–742K
6.
Ca2+‐activated K+ channel KCa1.1 as a therapeutic target to overcome chemoresistance in three‐dimensional sarcoma spheroid models
Susumu Ohya, Junko Kajikuri, Kyoko Endo, Hiroaki Kito, Elghareeb E. Elboray, Takayoshi Suzuki
Cancer Sci. 2021 Sep; 112(9): 3769–3783. Published online 2021 Jul 16. doi: 10.1111/cas.15046
PMCID:
PMC8409426
AbstractArticlePDF–1.7M
7.
TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase
Loretta Ferrera, Raffaella Barbieri, Cristiana Picco, Paolo Zuccolini, Alessia Remigante, Sara Bertelli, Maria Rita Fumagalli, Giovanni Zifarelli, Caterina A. M. La Porta, Paola Gavazzo, Michael Pusch
Int J Mol Sci. 2021 Aug; 22(16): 8359. Published online 2021 Aug 4. doi: 10.3390/ijms22168359
PMCID:
PMC8393965
AbstractArticlePDF–4.2M
8.
Single channel properties of mitochondrial large conductance potassium channel formed by BK-VEDEC splice variant
Shur Gałecka, Bogusz Kulawiak, Piotr Bednarczyk, Harpreet Singh, Adam Szewczyk
Sci Rep. 2021; 11: 10925. Published online 2021 May 25. doi: 10.1038/s41598-021-90465-3
PMCID:
PMC8149700
AbstractArticlePDF–2.6M
9.
Differences in Gating Dynamics of BK Channels in Cellular and Mitochondrial Membranes from Human Glioblastoma Cells Unraveled by Short- and Long-Range Correlations Analysis
Agata Wawrzkiewicz-Jałowiecka, Paulina Trybek, Przemysław Borys, Beata Dworakowska, Łukasz Machura, Piotr Bednarczyk
Cells. 2020 Oct; 9(10): 2305. Published online 2020 Oct 15. doi: 10.3390/cells9102305
PMCID:
PMC7602617
AbstractArticlePDF–1.2M
10.
Melatonin promotes sleep by activating the BK channel in C. elegans
Longgang Niu, Yan Li, Pengyu Zong, Ping Liu, Yuan Shui, Bojun Chen, Zhao-Wen Wang
Proc Natl Acad Sci U S A. 2020 Oct 6; 117(40): 25128–25137. Published online 2020 Sep 21. doi: 10.1073/pnas.2010928117
PMCID:
PMC7547285
AbstractArticlePDF–2.9M
11.
Aromatic interactions with membrane modulate human BK channel activation
Mahdieh Yazdani, Guohui Zhang, Zhiguang Jia, Jingyi Shi, Jianmin Cui, Jianhan Chen
eLife. 2020; 9: e55571. Published online 2020 Jun 29. doi: 10.7554/eLife.55571
PMCID:
PMC7371421
AbstractArticlePDF–3.6M
12.
Coupling of Ca2+ and voltage activation in BK channels through the αB helix/voltage sensor interface
Yanyan Geng, Zengqin Deng, Guohui Zhang, Gonzalo Budelli, Alice Butler, Peng Yuan, Jianmin Cui, Lawrence Salkoff, Karl L. Magleby
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14512–14521. Published online 2020 Jun 8. doi: 10.1073/pnas.1908183117
PMCID:
PMC7321994
AbstractArticlePDF–1.8M
13.
Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer
Gina Sizemore, Sarah McLaughlin, Mackenzie Newman, Kathleen Brundage, Amanda Ammer, Karen Martin, Elena Pugacheva, James Coad, Malcolm D. Mattes, Han-Gang Yu
BMC Cancer. 2020; 20: 595. Published online 2020 Jun 26. doi: 10.1186/s12885-020-07071-1
PMCID:
PMC7318490
AbstractArticlePDF–3.2M
14.
Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia
Xiaofei Du, Joao L. Carvalho-de-Souza, Cenfu Wei, Willy Carrasquel-Ursulaez, Yenisleidy Lorenzo, Naileth Gonzalez, Tomoya Kubota, Julia Staisch, Timothy Hain, Natalie Petrossian, Michael Xu, Ramon Latorre, Francisco Bezanilla, Christopher M. Gomez
Proc Natl Acad Sci U S A. 2020 Mar 17; 117(11): 6023–6034. Published online 2020 Mar 4. doi: 10.1073/pnas.1920008117
PMCID:
PMC7084159
AbstractArticlePDF–2.4M
15.
Comparative gain-of-function effects of the KCNMA1-N999S mutation on human BK channel properties
Hans J. Moldenhauer, Katia K. Matychak, Andrea L. Meredith
J Neurophysiol. 2020 Feb 1; 123(2): 560–570. Published online 2019 Dec 18. doi: 10.1152/jn.00626.2019
PMCID:
PMC7052641
AbstractArticle
16.
Molecular structures of the human Slo1 K+ channel in complex with β4
Xiao Tao, Roderick MacKinnon
eLife. 2019; 8: e51409. Published online 2019 Dec 9. doi: 10.7554/eLife.51409
PMCID:
PMC6934384
AbstractArticlePDF–5.2M
17.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
18.
Calcium-driven regulation of voltage-sensing domains in BK channels
Yenisleidy Lorenzo-Ceballos, Willy Carrasquel-Ursulaez, Karen Castillo, Osvaldo Alvarez, Ramon Latorre
eLife. 2019; 8: e44934. Published online 2019 Sep 11. doi: 10.7554/eLife.44934
PMCID:
PMC6763263
AbstractArticlePDF–2.3M
19.
Consequences of the Stoichiometry of Slo1 α and Auxiliary β Subunits on Functional Properties of Large-Conductance Ca2+-Activated K+Channels
Ying-Wei Wang, Jiu Ping Ding, Xiao-Ming Xia, Christopher J. Lingle
J Neurosci. 2002 Mar 1; 22(5): 1550–1561. doi: 10.1523/JNEUROSCI.22-05-01550.2002
PMCID:
PMC6758889
AbstractArticlePDF–682K
20.
Cloning and Characterization of Glioma BK, a Novel BK Channel Isoform Highly Expressed in Human Glioma Cells
Xiaojin Liu, Yongchan Chang, Peter H. Reinhart, Harald Sontheimer
J Neurosci. 2002 Mar 1; 22(5): 1840–1849. doi: 10.1523/JNEUROSCI.22-05-01840.2002
Correction in:
J Neurosci. 2002 Oct 15; 22(20): np.
PMCID:
PMC6758869
AbstractArticlePDF–323K

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