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Select item 88970221.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80459323.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 71699834.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 61666825.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 59275436.

RhoH participates in a multi-protein complex with the zinc finger protein kaiso that regulates both cytoskeletal structures and chemokine-induced T cells

Akihisa Mino, Anja Troeger, Christian Brendel, Alan Cantor, Chad Harris, Marioara F. Ciuculescu, David A. Williams

Small GTPases. 2018; 9(3): 260–273. Published online 2016 Aug 31. doi: 10.1080/21541248.2016.1220780

PMCID:: PMC5927543

Abstract Article PDF–1.0M

Select item 58407767.

An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration

Virginia Tajadura-Ortega, Ritu Garg, Richard Allen, Claudia Owczarek, Michael D. Bright, Samuel Kean, Aisyah Mohd-Noor, Anita Grigoriadis, Timothy C. Elston, Klaus M. Hahn, Anne J. Ridley

BMC Biol. 2018; 16: 29. Published online 2018 Mar 6. doi: 10.1186/s12915-018-0489-4

PMCID:: PMC5840776

Abstract Article PDF–3.7M

Select item 51364858.

RhoH is a negative regulator of eosinophilopoiesis

Christina Stoeckle, Barbara Geering, Shida Yousefi, Saša Rožman, Nicola Andina, Charaf Benarafa, Hans-Uwe Simon

Cell Death Differ. 2016 Dec; 23(12): 1961–1972. Published online 2016 Oct 14. doi: 10.1038/cdd.2016.73

PMCID:: PMC5136485

Abstract Article PDF–2.6M

Select item 39970559.

Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders

Anja Troeger, David A Williams

Exp Cell Res. Author manuscript; available in PMC 2014 Sep 10.

Published in final edited form as: Exp Cell Res. 2013 Sep 10; 319(15): 2375–2383. Published online 2013 Jul 11. doi: 10.1016/j.yexcr.2013.07.002

PMCID:: PMC3997055

Abstract Article PDF–1.0M

Select item 386922610.

Involvement of RhoH GTPase in the Development of B-Cell Chronic Lymphocytic Leukemia

Abel Sanchez-Aguilera, Ina Rattmann, David Z. Drew, Lars U.W. Müller, Victoria Summey, David M. Lucas, John C. Byrd, Carlo M. Croce, Yi Gu, Jose A. Cancelas, Patrick Johnston, Thomas Moritz, David A. Williams

Leukemia. Author manuscript; available in PMC 2013 Dec 20.

Published in final edited form as: Leukemia. 2010 Jan; 24(1): 97–104. Published online 2009 Oct 22. doi: 10.1038/leu.2009.217

PMCID:: PMC3869226

Abstract Article PDF–1.3M

Select item 342808911.

Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections

Amandine Crequer, Anja Troeger, Etienne Patin, Cindy S. Ma, Capucine Picard, Vincent Pedergnana, Claire Fieschi, Annick Lim, Avinash Abhyankar, Laure Gineau, Ingrid Mueller-Fleckenstein, Monika Schmidt, Alain Taieb, James Krueger, Laurent Abel, Stuart G. Tangye, Gérard Orth, David A. Williams, Jean-Laurent Casanova, Emmanuelle Jouanguy

J Clin Invest. 2012 Sep 4; 122(9): 3239–3247. Published online 2012 Aug 1. doi: 10.1172/JCI62949

PMCID:: PMC3428089

Abstract Article PDF–1.1M

Select item 338710912.

Opposing roles for RhoH GTPase during T-cell migration and activation

Christina M. Baker, William A. Comrie, Young-Min Hyun, Hung-Li Chung, Christine A. Fedorchuk, Kihong Lim, Cord Brakebusch, James L. McGrath, Richard E. Waugh, Martin Meier-Schellersheim, Minsoo Kim

Proc Natl Acad Sci U S A. 2012 Jun 26; 109(26): 10474–10479. Published online 2012 Jun 11. doi: 10.1073/pnas.1114214109

PMCID:: PMC3387109

Abstract Article PDF–615K

Select item 336787413.

RhoH is critical for cell-microenvironment interactions in chronic lymphocytic leukemia in mice and humans

Anja Troeger, Amy J. Johnson, Jenna Wood, William G. Blum, Leslie A. Andritsos, John C. Byrd, David A. Williams

Blood. 2012 May 17; 119(20): 4708–4718. Prepublished online 2012 Apr 3. doi: 10.1182/blood-2011-12-395939

PMCID:: PMC3367874

Abstract Article

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 298047715.

RhoH Regulates Subcellular Localization of ZAP-70 and Lck in T Cell Receptor Signaling

Hee-Don Chae, Jamie E. Siefring, David A. Hildeman, Yi Gu, David A. Williams

PLoS One. 2010; 5(11): e13970. Published online 2010 Nov 12. doi: 10.1371/journal.pone.0013970

PMCID:: PMC2980477

Abstract Article PDF–1.2M

Select item 293634316.

The haematopoietic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression

Mehtap S Gündogdu, He Liu, Daniela Metzdorf, Dagmar Hildebrand, Michael Aigner, Klaus Aktories, Klaus Heeg, Katharina F Kubatzky

Mol Cancer. 2010; 9: 225. Published online 2010 Aug 25. doi: 10.1186/1476-4598-9-225

PMCID:: PMC2936343

Abstract Article PDF–1010K

Select item 289646417.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 266530418.

Evolution of the Rho family of ras-like GTPases in eukaryotes

Anthony Boureux, Emmanuel Vignal, Sandrine Faure, Philippe Fort

Mol Biol Evol. Author manuscript; available in PMC 2009 Apr 6.

Published in final edited form as: Mol Biol Evol. 2007 Jan; 24(1): 203–216. Published online 2006 Oct 11. doi: 10.1093/molbev/msl145

PMCID:: PMC2665304

Abstract Article

Select item 135612919.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 52892820.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

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