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Select item 112465871.

EGFR mutations induce the suppression of CD8⁺ T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-β axis in non-small cell lung cancer

Huayan Huang, Xiaokuan Zhu, Yongfeng Yu, Ziming Li, Yi Yang, Liliang Xia, Shun Lu

J Transl Med. 2024; 22: 653. Published online 2024 Jul 14. doi: 10.1186/s12967-024-05456-5

PMCID:: PMC11246587

Abstract Article PDF–5.9M

Select item 112380762.

TGFβ overcomes FGF-induced transinhibition of EGFR in lens cells to enable fibrotic secondary cataract

Judy K. VanSlyke, Bruce A. Boswell, Linda S. Musil

Mol Biol Cell. 2024 Jun 1; 35(6): ar75. Published online 2024 May 6. doi: 10.1091/mbc.E24-01-0040

PMCID:: PMC11238076

Abstract Article PDF–1.8M

Select item 111616323.

SNX16 is required for hepatocellular carcinoma survival via modulating the EGFR-AKT signaling pathway

Lebin Yuan, Yanqiu Meng, Jiajia Xiang

Sci Rep. 2024; 14: 13093. Published online 2024 Jun 7. doi: 10.1038/s41598-024-64015-6

PMCID:: PMC11161632

Abstract Article PDF–17M

Select item 111602084.

Redifferentiation and ZO‐1 reexpression in liver‐metastasized colorectal cancer: Possible association with epidermal growth factor receptor‐induced tyrosine phosphorylation of ZO‐1

Tsukasa Kaihara, Hitoshi Kawamata, Johji Imura, Shigehiko Fujii, Kazuaki Kitajima, Fumie Omotehara, Naomi Maeda, Tetsuya Nakamura, Takahiro Fujimori

Cancer Sci. 2003 Feb; 94(2): 166–172. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01414.x

PMCID:: PMC11160208

Abstract Article PDF–742K

Select item 111601455.

Expression of constitutively activated EGFRvlll in non‐small cell lung cancer

Isamu Okamoto, Lawrence C. Kenyon, David R. Emlet, Takeshi Mori, Ji‐ichiro Sasaki, Susumu Hirosako, Yasuko Ichikawa, Hiroto Kishi, Andrew K. Godwin, Masakazu Yoshioka, Moritaka Suga, Mitsuhiro Matsumoto, Albert J. Wong

Cancer Sci. 2003 Jan; 94(1): 50–56. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01351.x

PMCID:: PMC11160145

Abstract Article PDF–969K

Select item 111600496.

Hypoxia increases the motility of lung adenocarcinoma cell line A549 via activation of the epidermal growth factor receptor pathway

Tao Wang, Toshiro Niki, Akiteru Goto, Satoshi Ota, Teppei Morikawa, Yu Nakamura, Etsuko Ohara, Shumpei Ishikawa, Hiroyuki Aburatani, Jun Nakajima, Masashi Fukayama

Cancer Sci. 2007 Apr; 98(4): 506–511. Published online 2007 Mar 14. doi: 10.1111/j.1349-7006.2007.00428.x

PMCID:: PMC11160049

Abstract Article PDF–218K

Select item 111598087.

Gene expression profiling of epidermal growth factor receptor/KRAS pathway activation in lung adenocarcinoma

Tatsuhiro Shibata, Satoko Hanada, Akiko Kokubu, Yoshihiro Matsuno, Hisao Asamura, Tsutomu Ohta, Michiie Sakamoto, Setsuo Hirohashi

Cancer Sci. 2007 Jul; 98(7): 985–991. Published online 2007 Apr 23. doi: 10.1111/j.1349-7006.2007.00483.x

PMCID:: PMC11159808

Abstract Article PDF–349K

Select item 111597698.

Exon 19 of EGFR mutation in relation to the CA‐repeat polymorphism in intron 1

Naoko Sueoka‐Aragane, Kazue Imai, Kazutoshi Komiya, Akemi Sato, Rika Tomimasu, Takashi Hisatomi, Toru Sakuragi, Masahiro Mitsuoka, Shinichiro Hayashi, Kei Nakachi, Eisaburo Sueoka

Cancer Sci. 2008 Jun; 99(6): 1180–1187. Published online 2008 Apr 14. doi: 10.1111/j.1349-7006.2008.00804.x

PMCID:: PMC11159769

Abstract Article PDF–325K

Select item 111595139.

Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells

Yin‐Hsun Feng, Chao‐Jung Tsao, Chao‐Liang Wu, Jan‐Gowth Chang, Pei‐Jung Lu, Kun‐Tu Yeh, Gia‐Shing Shieh, Ai‐Li Shiau, Jeng‐Chang Lee

Cancer Sci. 2010 Sep; 101(9): 2033–2038. Published online 2010 Jun 7. doi: 10.1111/j.1349-7006.2010.01637.x

PMCID:: PMC11159513

Abstract Article PDF–521K

Select item 1115949810.

Soy consumption reduces the risk of non‐small‐cell lung cancers with epidermal growth factor receptor mutations among Japanese

Keitaro Matsuo, Akio Hiraki, Hidemi Ito, Takayuki Kosaka, Takeshi Suzuki, Kaoru Hirose, Kenji Wakai, Yasushi Yatabe, Tetsuya Mitsudomi, Kazuo Tajima

Cancer Sci. 2008 Jun; 99(6): 1202–1208. Published online 2008 Apr 21. doi: 10.1111/j.1349-7006.2008.00812.x

PMCID:: PMC11159498

Abstract Article PDF–99K

Select item 1115932411.

Protein overexpression and gene amplification of epidermal growth factor receptor in adult testicular germ cell tumors: Potential role in tumor progression

Kosuke Miyai, Sohei Yamamoto, Tomohiko Asano, Seiichi Tamai, Osamu Matsubara, Hitoshi Tsuda

Cancer Sci. 2010 Sep; 101(9): 1970–1976. Published online 2010 Jun 7. doi: 10.1111/j.1349-7006.2010.01638.x

PMCID:: PMC11159324

Abstract Article PDF–638K

Select item 1115922112.

Predictive advantage of a cell type classification for pulmonary adenocarcinoma coupled with data for p53, K‐ras and EGFR alterations

Akira Okada, Takuo Shimmyo, Takehisa Hashimoto, Yasuhito Kobayashi, Yohei Miyagi, Yuichi Ishikawa, Ken Nakagawa, Junichi Hayashi, Eiju Tsuchiya

Cancer Sci. 2010 Jul; 101(7): 1745–1753. Published online 2010 Apr 7. doi: 10.1111/j.1349-7006.2010.01585.x

PMCID:: PMC11159221

Abstract Article PDF–366K

Select item 1115909113.

Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung

Tomoya Fukui, Koji Tsuta, Koh Furuta, Shun‐ichi Watanabe, Hisao Asamura, Yuichiro Ohe, Akiko Miyagi Maeshima, Tatsuhiro Shibata, Noriyuki Masuda, Yoshihiro Matsuno

Cancer Sci. 2007 Nov; 98(11): 1714–1719. Published online 2007 Sep 2. doi: 10.1111/j.1349-7006.2007.00600.x

PMCID:: PMC11159091

Abstract Article PDF–979K

Select item 1115908214.

Antitumor activity of cetuximab against malignant glioma cells overexpressing EGFR deletion mutant variant III

Junya Fukai, Kazuto Nishio, Toru Itakura, Fumiaki Koizumi

Cancer Sci. 2008 Oct; 99(10): 2062–2069. Published online 2008 Oct 3. doi: 10.1111/j.1349-7006.2008.00945.x

PMCID:: PMC11159082

Abstract Article PDF–411K

Select item 1115889115.

Epidermal growth factor receptor mutation, but not sex and smoking, is independently associated with favorable prognosis of gefitinib‐treated patients with lung adenocarcinoma

Shinichi Toyooka, Toshimi Takano, Takayuki Kosaka, Katsuyuki Hotta, Keitaro Matsuo, Shuji Ichihara, Yoshiro Fujiwara, Junichi Soh, Hiroki Otani, Katsuyuki Kiura, Keisuke Aoe, Yasushi Yatabe, Yuichiro Ohe, Tetsuya Mitsudomi, Hiroshi Date

Cancer Sci. 2008 Feb; 99(2): 303–308. Published online 2008 Feb 6. doi: 10.1111/j.1349-7006.2007.00688.x

PMCID:: PMC11158891

Abstract Article PDF–226K

Select item 1115888616.

Intratumor heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib

Kazuya Taniguchi, Jiro Okami, Ken Kodama, Masahiko Higashiyama, Kikuya Kato

Cancer Sci. 2008 May; 99(5): 929–935. Published online 2008 Mar 4. doi: 10.1111/j.1349-7006.2008.00782.x

PMCID:: PMC11158886

Abstract Article PDF–1.1M

Select item 1115888317.

Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6

Sae‐Won Han, Do‐Youn Oh, Seock‐Ah Im, Sook Ryun Park, Keun‐Wook Lee, Hong Suk Song, Nam‐Su Lee, Kyung Hee Lee, In Sil Choi, Moon Hee Lee, Min A Kim, Woo Ho Kim, Yung‐Jue Bang, Tae‐You Kim

Cancer Sci. 2010 Mar; 101(3): 793–799. Published online 2009 Nov 23. doi: 10.1111/j.1349-7006.2009.01447.x

PMCID:: PMC11158883

Abstract Article PDF–174K

Select item 1115850818.

Association of epidermal growth factor receptor (EGFR) gene mutations with EGFR amplification in advanced non‐small cell lung cancer

Ryotaro Morinaga, Isamu Okamoto, Yoshihiko Fujita, Tokuzo Arao, Masaru Sekijima, Kazuto Nishio, Hiroyuki Ito, Masahiro Fukuoka, Jun‐ichi Kadota, Kazuhiko Nakagawa

Cancer Sci. 2008 Dec; 99(12): 2455–2460. Published online 2008 Oct 16. doi: 10.1111/j.1349-7006.2008.00962.x