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Select item 92626141.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 84699212.

Evaluation of WNT Signaling Pathway Gene Variants WNT7B rs6519955, SFRP4 rs17171229 and RSPO2 rs611744 in Patients with Dupuytren’s Contracture

Gediminas Samulėnas, Alina Smalinskienė, Rytis Rimdeika, Kęstutis Braziulis, Mantas Fomkinas, Rokas Paškevičius

Genes (Basel) 2021 Sep; 12(9): 1293. Published online 2021 Aug 24. doi: 10.3390/genes12091293

PMCID:: PMC8469921

Abstract Article PDF–237K

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81241134.

Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer

Zhongbo Zhang, Yuanhong Xu, Chenghai Zhao

Cancer Med. 2021 May; 10(10): 3332–3345. Published online 2021 May 2. doi: 10.1002/cam4.3819

PMCID:: PMC8124113

Abstract Article PDF–2.5M

Select item 78937515.

Activation of WNT7b autocrine eases metastasis of colorectal cancer via epithelial to mesenchymal transition and predicts poor prognosis

Shuai Jiang, Qiwen Li, Yimin Liu, Huimin Zhang, Qianyu Wang, Yu Chen, Xiaoyang Shi, Jun Li, Hailing Zhang, Yi Zhang, Dongqing Xia, Man Wu, Jiajia Lin, Chenglin Zhang, Suhua Pang, Jiamin Jiang, Yan Wen, Peipei Zhang

BMC Cancer. 2021; 21: 180. Published online 2021 Feb 19. doi: 10.1186/s12885-021-07898-2

PMCID:: PMC7893751

Abstract Article PDF–2.0M

Select item 78511436.

A WNT7B-m⁶A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis

Qian Gao, Liuyang Yang, Aolin Shen, Yang Li, Yongxiang Li, Shilian Hu, Runhuai Yang, Xiangting Wang, Xuebiao Yao, Guodong Shen

Signal Transduct Target Ther. 2021; 6: 43. Published online 2021 Feb 2. doi: 10.1038/s41392-020-00397-z

PMCID:: PMC7851143

Article PDF–1.1M

Select item 78376807.

Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells

Andrea Cipriano, Martina Macino, Giulia Buonaiuto, Tiziana Santini, Beatrice Biferali, Giovanna Peruzzi, Alessio Colantoni, Chiara Mozzetta, Monica Ballarino

eLife. 2021; 10: e54782. Published online 2021 Jan 12. doi: 10.7554/eLife.54782

PMCID:: PMC7837680

Abstract Article PDF–1.8M

Select item 76877418.

Extracellular vesicular Wnt7b mediates HPV E6-induced cervical cancer angiogenesis by activating the β-catenin signaling pathway

Jun-Jun Qiu, Shu-Gen Sun, Xiao-Yan Tang, Ying-Ying Lin, Ke-Qin Hua

J Exp Clin Cancer Res. 2020; 39: 260. Published online 2020 Nov 25. doi: 10.1186/s13046-020-01745-1

PMCID:: PMC7687741

Abstract Article PDF–4.9M

Select item 74478079.

TCP1 regulates Wnt7b/β-catenin pathway through P53 to influence the proliferation and migration of hepatocellular carcinoma cells

Nanhong Tang, Xiaoling Cai, Lirong Peng, Hekun Liu, Yuanzhong Chen

Signal Transduct Target Ther. 2020; 5: 169. Published online 2020 Aug 25. doi: 10.1038/s41392-020-00278-5

PMCID:: PMC7447807

Article PDF–1.1M

Select item 744129510.

Association of WNT7B and RSPO1 with Axial Length in School Children

Shi Yao Lu, Shu Min Tang, Fen Fen Li, Ka Wai Kam, Pancy O S. Tam, Wilson W K. Yip, Alvin L. Young, Clement C. Tham, Chi Pui Pang, Jason C. Yam, Li Jia Chen

Invest Ophthalmol Vis Sci. 2020 Aug; 61(10): 11. Published online 2020 Aug 6. doi: 10.1167/iovs.61.10.11

PMCID:: PMC7441295

Abstract Article PDF–228K

Select item 692775411.

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong

eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223

PMCID:: PMC6927754

Abstract Article PDF–5.1M

Select item 692770712.

miR-342-5p inhibits osteosarcoma cell growth, migration, invasion, and sensitivity to Doxorubicin through targeting Wnt7b

Qing Liu, Zhenting Wang, Xiaohua Zhou, Mingying Tang, Wei Tan, Tianshi Sun, Youwen Deng

Cell Cycle. 2019; 18(23): 3325–3336. Published online 2019 Oct 10. doi: 10.1080/15384101.2019.1676087

PMCID:: PMC6927707

Abstract Article PDF–5.5M

Select item 667787813.

Narrowband UVB treatment induces expression of WNT7B, WNT10B and TCF7L2 in psoriasis skin

Malin Assarsson, Jan Söderman, Albert Duvetorp, Ulrich Mrowietz, Marita Skarstedt, Oliver Seifert

Arch Dermatol Res. 2019; 311(7): 535–544. Published online 2019 May 14. doi: 10.1007/s00403-019-01931-y

PMCID:: PMC6677878

Abstract Article PDF–1.5M

Select item 645830814.

Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition

Lei Gao, Yong Hu, Yahui Tian, Zhenzhen Fan, Kun Wang, Hongdan Li, Qian Zhou, Guandi Zeng, Xin Hu, Lei Yu, Shiyu Zhou, Xinyuan Tong, Hsinyi Huang, Haiquan Chen, Qingsong Liu, Wanting Liu, Gong Zhang, Musheng Zeng, Guangbiao Zhou, Qingyu He, Hongbin Ji, Liang Chen

Nat Commun. 2019; 10: 1665. Published online 2019 Apr 10. doi: 10.1038/s41467-019-09295-7

PMCID:: PMC6458308

Abstract Article PDF–2.2M

Select item 621117215.

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

Amelie Griveau, Giorgio Seano, Samuel J. Shelton, Robert Kupp, Arman Jahangiri, Kirsten Obernier, Shanmugarajan Krishnan, Olle R. Lindberg, Tracy J. Yuen, An-Chi Tien, Jennifer K. Sabo, Nancy Wang, Ivy Chen, Jonas Kloepper, Louis Larrouquere, Mitrajit Ghosh, Itay Tirosh, Emmanuelle Huillard, Arturo Alvarez-Buylla, Michael C. Oldham, Anders I. Persson, William A. Weiss, Tracy T. Batchelor, Anat Stemmer-Rachamimov, Mario L. Suvà, Joanna J. Phillips, Manish K. Aghi, Shwetal Mehta, Rakesh K. Jain, David H. Rowitch

Cancer Cell. Author manuscript; available in PMC 2018 Nov 14.

Published in final edited form as: Cancer Cell. 2018 May 14; 33(5): 874–889.e7. Published online 2018 Apr 19. doi: 10.1016/j.ccell.2018.03.020

PMCID:: PMC6211172

Abstract Article PDF–4.2M

Select item 607859216.

Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos

Xiaoyi Gao, Drew R. Nannini, Kristen Corrao, Mina Torres, Yii-Der I. Chen, Bao J. Fan, Janey L. Wiggs, International Glaucoma Genetics Consortium, Kent D. Taylor, W. James Gauderman, Jerome I. Rotter, Rohit Varma

Hum Mol Genet. 2016 Nov 15; 25(22): 5035–5045. Published online 2016 Sep 20. doi: 10.1093/hmg/ddw319

PMCID:: PMC6078592

Abstract Article PDF–416K

Select item 596122017.

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

Bao Jian Fan, Xueli Chen, Nisha Sondhi, P. Ferdinamarie Sharmila, Nagasamy Soumittra, Sarangapani Sripriya, Srinivasan Sacikala, Rashima Asokan, David S. Friedman, Louis R. Pasquale, X. Raymond Gao, Lingam Vijaya, Jessica Cooke Bailey, Veronique Vitart, Stuart MacGregor, Christopher J. Hammond, Chiea Chuen Khor, Jonathan L. Haines, Ronnie George, Janey L. Wiggs, for the Mexican American Glaucoma Genetic Study; International Glaucoma Genetics Consortium; and NEIGHBORHOOD Consortium

Invest Ophthalmol Vis Sci. 2018 May; 59(6): 2495–2502. doi: 10.1167/iovs.17-23536

PMCID:: PMC5961220

Abstract Article PDF–573K

Select item 567858118.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 563670319.

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families

Oksana Voloshanenko, Philipp Gmach, Jan Winter, Dominique Kranz, Michael Boutros

FASEB J. 2017 Nov; 31(11): 4832–4844. Published online 2017 Jul 21. doi: 10.1096/fj.201700144R

PMCID:: PMC5636703

Abstract Article

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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Male and female in vitro cultured placental cell types
Male and female in vitro cultured placental cell types
Accession: GDS5016

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Stage I endometrial cancer: microdissected frozen uterine tumors
Stage I endometrial cancer: microdissected frozen uterine tumors
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