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Items: 1 to 20 of 28

1.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
2.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
3.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export
Dick J. H. van den Boomen, Agata Sienkiewicz, Ilana Berlin, Marlieke L. M. Jongsma, Daphne M. van Elsland, J. Paul Luzio, Jacques J. C. Neefjes, Paul J. Lehner
Nat Commun. 2020; 11: 5559. Published online 2020 Nov 3. doi: 10.1038/s41467-020-19032-0
PMCID:
PMC7642327
AbstractArticlePDF–12M
6.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
7.
The Role of Two-Pore Channels in Norepinephrine-Induced [Ca2+]i Rise in Rat Aortic Smooth Muscle Cells and Aorta Contraction
Sergei K. Trufanov, Elena Yu. Rybakova, Piotr P. Avdonin, Alexandra A. Tsitrina, Irina L. Zharkikh, Nikolay V. Goncharov, Richard O. Jenkins, Pavel V. Avdonin
Cells. 2019 Oct; 8(10): 1144. Published online 2019 Sep 25. doi: 10.3390/cells8101144
PMCID:
PMC6829401
AbstractArticlePDF–5.0M
8.
Reconstituted Human TPC1 Is a Proton-Permeable Ion Channel and Is Activated by NAADP or Ca2+
Samantha J. Pitt, Andy K. M. Lam, Katja Rietdorf, Antony Galione, Rebecca Sitsapesan
Sci Signal. Author manuscript; available in PMC 2019 Jul 31.
Published in final edited form as: Sci Signal. 2014 May 20; 7(326): ra46. Published online 2014 May 20. doi: 10.1126/scisignal.2004854
PMCID:
PMC6669042
AbstractArticlePDF–1.5M
9.
Structural mechanisms of phospholipid activation of the human TPC2 channel
Ji She, Weizhong Zeng, Jiangtao Guo, Qingfeng Chen, Xiao-chen Bai, Youxing Jiang
eLife. 2019; 8: e45222. Published online 2019 Mar 12. doi: 10.7554/eLife.45222
PMCID:
PMC6424560
AbstractArticlePDF–2.7M
10.
NAADP-evoked Ca2+ signals through two-pore channel-1 require arginine residues in the first S4-S5 linker
Sandip Patel, Dev Churamani, Eugen Brailoiu
Cell Calcium. 2017 Dec; 68: 1–4. doi: 10.1016/j.ceca.2017.09.003
PMCID:
PMC5700777
AbstractArticle
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
The human two-pore channel 1 is modulated by cytosolic and luminal calcium
Laura Lagostena, Margherita Festa, Michael Pusch, Armando Carpaneto
Sci Rep. 2017; 7: 43900. Published online 2017 Mar 2. doi: 10.1038/srep43900
PMCID:
PMC5333365
AbstractArticlePDF–1.3M
13.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
14.
Two-pore channel 1 interacts with citron kinase, regulating completion of cytokinesis
Jaime S Horton, Clay T Wakano, Mark Speck, Alexander J Stokes
Channels (Austin) 2015 Jan-Feb; 9(1): 21–29. Published online 2015 Feb 9. doi: 10.4161/19336950.2014.978676
PMCID:
PMC4594595
AbstractArticlePDF–583K
15.
Two pore channels control Ebolavirus host cell entry and are drug targets for disease treatment
Yasuteru Sakurai, Andrey A. Kolokoltsov, Cheng-Chang Chen, Michael W. Tidwell, William E. Bauta, Norbert Klugbauer, Christian Grimm, Christian Wahl-Schott, Martin Biel, Robert A. Davey
Science. Author manuscript; available in PMC 2016 Feb 27.
Published in final edited form as: Science. 2015 Feb 27; 347(6225): 995–998. doi: 10.1126/science.1258758
PMCID:
PMC4550587
AbstractArticlePDF–724K
16.
Organelle-specific Subunit Interactions of the Vertebrate Two-pore Channel Family
Oluseye A. Ogunbayo, Yingmin Zhu, Bing Shen, Ejaife Agbani, Jie Li, Jianjie Ma, Michael X. Zhu, A. Mark Evans
J Biol Chem. 2015 Jan 9; 290(2): 1086–1095. Published online 2014 Dec 1. doi: 10.1074/jbc.M114.610493
PMCID:
PMC4294476
AbstractArticlePDF–2.8M
17.
The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation
Yaping Lin-Moshier, Michael V. Keebler, Robert Hooper, Michael J. Boulware, Xiaolong Liu, Dev Churamani, Mary E. Abood, Timothy F. Walseth, Eugen Brailoiu, Sandip Patel, Jonathan S. Marchant
Proc Natl Acad Sci U S A. 2014 Sep 9; 111(36): 13087–13092. Published online 2014 Aug 25. doi: 10.1073/pnas.1407004111
PMCID:
PMC4246952
AbstractArticlePDF–1.2M
18.
Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network
S Aslibekyan, P An, AC Frazier-Wood, EK Kabagambe, MR Irvin, RJ Straka, HK Tiwari, MY Tsai, PN Hopkins, IB Borecki, JM Ordovas, DK Arnett
Nutr Metab Cardiovasc Dis. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Nutr Metab Cardiovasc Dis. 2013 Oct; 23(10): 10.1016/j.numecd.2012.07.010. Published online 2012 Nov 11. doi: 10.1016/j.numecd.2012.07.010
PMCID:
PMC3578131
AbstractArticlePDF–548K
19.
TPC Proteins Are Phosphoinositide-activated Sodium-selective Ion Channels in Endosomes and Lysosomes
Xiang Wang, Xiaoli Zhang, Xian-ping Dong, Mohammad Samie, Xinran Li, Xiping Cheng, Andrew Goschka, Dongbiao Shen, Yandong Zhou, Janice Harlow, Michael X. Zhu, David E. Clapham, Dejian Ren, Haoxing Xu
Cell. Author manuscript; available in PMC 2013 Oct 12.
Published in final edited form as: Cell. 2012 Oct 12; 151(2): 372–383. doi: 10.1016/j.cell.2012.08.036
PMCID:
PMC3475186
AbstractArticlePDF–3.4M
20.
Membrane Potential Regulates Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Dependence of the pH- and Ca2+-sensitive Organellar Two-pore Channel TPC1
Volodymyr Rybalchenko, Malini Ahuja, Jessica Coblentz, Dev Churamani, Sandip Patel, Krill Kiselyov, Shmuel Muallem
J Biol Chem. 2012 Jun 8; 287(24): 20407–20416. Published online 2012 Apr 12. doi: 10.1074/jbc.M112.359612
PMCID:
PMC3370221
AbstractArticlePDF–2.4M

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