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Select item 111295371.

GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis

Boyuan Chen, Weihao Fu, Chunyang Jie, Guoxiu Zhang, Zhen Li, Yihai Liu, Shibo Zhou

Mol Med Rep. 2024 Jul; 30(1): 118. Published online 2024 May 14. doi: 10.3892/mmr.2024.13242

PMCID:: PMC11129537

Abstract Article PDF–5.1M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 90187253.

Comprehensive analysis of epigenetics regulation, prognostic and the correlation with immune infiltrates of GPX7 in adult gliomas

Wallax Augusto Silva Ferreira, Glauco Akelinghton Freire Vitiello, Tiago da Silva Medina, Edivaldo Herculano Correa de Oliveira

Sci Rep. 2022; 12: 6442. Published online 2022 Apr 19. doi: 10.1038/s41598-022-10114-1

PMCID:: PMC9018725

Abstract Article PDF–87M

Select item 87600774.

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord

Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6

PMCID:: PMC8760077

Abstract Article PDF–12M

Select item 85813135.

GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway

Xuchen Hu, Boer Li, Fanzi Wu, Xiaoyu Liu, Mengyu Liu, Chenglin Wang, Yu Shi, Ling Ye

J Cell Mol Med. 2021 Nov; 25(22): 10454–10465. Published online 2021 Oct 9. doi: 10.1111/jcmm.16974

PMCID:: PMC8581313

Abstract Article PDF–2.2M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74767147.

Characterization of the endoplasmic reticulum–resident peroxidases GPx7 and GPx8 shows the higher oxidative activity of GPx7 and its linkage to oxidative protein folding

Shingo Kanemura, Elza Firdiani Sofia, Naoya Hirai, Masaki Okumura, Hiroshi Kadokura, Kenji Inaba

J Biol Chem. 2020 Sep 4; 295(36): 12772–12785. Published online 2020 Jul 21. doi: 10.1074/jbc.RA120.013607

PMCID:: PMC7476714

Abstract Article PDF–3.0M

Select item 71699838.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 492871610.

HIV–host interactome revealed directly from infected cells

Yang Luo, Erica Y. Jacobs, Todd M. Greco, Kevin D. Mohammed, Tommy Tong, Sarah Keegan, James M. Binley, Ileana M. Cristea, David Fenyö, Michael P. Rout, Brian T. Chait, Mark A. Muesing

Nat Microbiol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Nat Microbiol. 2016 Jul; 1(7): 16068. Published online 2016 May 23. doi: 10.1038/nmicrobiol.2016.68

PMCID:: PMC4928716

Abstract Article PDF–1.1M

Select item 469861011.

GPX4 and GPX7 Over-Expression in Human Hepatocellular Carcinoma Tissues

E. Guerriero, F. Capone, M. Accardo, A. Sorice, M. Costantini, G. Colonna, G. Castello, S. Costantini

Eur J Histochem. 2015 Oct 26; 59(4): 2540. Published online 2015 Dec 1. doi: 10.4081/ejh.2015.2540

PMCID:: PMC4698610

Abstract Article PDF–2.1M

Select item 462705412.

NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress

Po-Jen Chen, Jui-Yun Weng, Pang-Hung Hsu, Jin-Yuh Shew, Yi-Shuian Huang, Wen-Hwa Lee

Nucleic Acids Res. 2015 Oct 30; 43(19): 9393–9404. Published online 2015 Oct 7. doi: 10.1093/nar/gkv1010

PMCID:: PMC4627054

Abstract Article PDF–2.0M

Select item 433432013.

Candidate pathway-based genetic association study of Platinum and Platinum-Taxane Related Toxicity in a Cohort of Primary Lung Cancer Patients

Cassandra Johnson, Vernon S. Pankratz, Ana I. Velazquez, Jeremiah A. Aakre, Charles L. Loprinzi, Nathan P. Staff, Anthony J. Windebank, Ping Yang

J Neurol Sci. Author manuscript; available in PMC 2016 Feb 15.

Published in final edited form as: J Neurol Sci. 2015 Feb 15; 349(0): 124–128. Published online 2015 Jan 5. doi: 10.1016/j.jns.2014.12.041

PMCID:: PMC4334320

Abstract Article PDF–260K

Select item 426658814.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 407681415.

Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett’s carcinogenesis

Dun-Fa Peng, Tian-Ling Hu, Mohammed Soutto, Abbes Belkhiri, Wael El-Rifai

Carcinogenesis. 2014 Jul; 35(7): 1620–1628. Published online 2014 Apr 1. doi: 10.1093/carcin/bgu083

PMCID:: PMC4076814

Abstract Article PDF–2.8M

Select item 394445916.

Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human

Yi-Cheng Chang, Yu-Hsiang Yu, Jin-Yuh Shew, Wei-Jei Lee, Juey-Jen Hwang, Yen-Hui Chen, Yet-Ran Chen, Pei-Chi Wei, Lee-Ming Chuang, Wen-Hwa Lee

EMBO Mol Med. 2013 Aug; 5(8): 1165–1179. Published online 2013 Jul 4. doi: 10.1002/emmm.201302679

PMCID:: PMC3944459

Abstract Article PDF–1.3M

Select item 390132117.

Glutathione Peroxidase 7 Utilizes Hydrogen Peroxide Generated by Ero1α to Promote Oxidative Protein Folding

Lei Wang, Lihui Zhang, Yingbo Niu, Roberto Sitia, Chih-chen Wang

Antioxid Redox Signal. 2014 Feb 1; 20(4): 545–556. doi: 10.1089/ars.2013.5236

PMCID:: PMC3901321

Abstract Article PDF–850K

Select item 382578318.

Glutathione peroxidase 7 has potential tumor suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma

DunFa Peng, TianLing Hu, Mohammed Soutto, Abbes Belkhiri, Alexander Zaika, Wael El-Rifai

Gut. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Gut. 2014 Apr; 63(4): 540–551. Published online 2013 Apr 12. doi: 10.1136/gutjnl-2013-304612

PMCID:: PMC3825783

Abstract Article PDF–6.2M

Select item 358235919.

Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease

Pei-Chi Wei, Yi-Hsuan Hsieh, Mei-I Su, X-J Jiang, Pang-Hung Hsu, Wen-Ting Lo, Yung-Ming Jeng, Ju-Ming Wang, Phang-lang Chen, Yi-Cheng Chang, Kuo-Fen Lee, Ming-Daw Tsai, Jin-Yuh Shew, Wen-Hwa Lee

Mol Cell. Author manuscript; available in PMC 2013 Dec 14.

Published in final edited form as: Mol Cell. 2012 Dec 14; 48(5): 747–759. Published online 2012 Nov 1. doi: 10.1016/j.molcel.2012.10.007

PMCID:: PMC3582359

Abstract Article PDF–5.6M

Select item 341930720.

Glutathione Peroxidase 7 Protects Against Oxidative DNA Damage in Oesophageal Cells

DunFa Peng, Abbes Belkhiri, TianLing Hu, Rupesh Chaturvedi, Mohammad Asim, Keith T. Wilson, Alexander Zaika, Wael El-Rifai

Gut. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Gut. 2012 Sep; 61(9): 1250–1260. Published online 2011 Dec 9. doi: 10.1136/gutjnl-2011-301078

PMCID:: PMC3419307

Abstract Article PDF–6.0M

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