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Select item 111784971.

TIMP-1 is an activator of MHC-I expression in myeloid dendritic cells with implications for tumor immunogenicity

Miriam Langguth, Eleftheria Maranou, Saara A. Koskela, Oskar Elenius, Roosa E. Kallionpää, Eva-Maria Birkman, Otto I. Pulkkinen, Maria Sundvall, Marko Salmi, Carlos R. Figueiredo

Genes Immun. 2024; 25(3): 188–200. Published online 2024 May 22. doi: 10.1038/s41435-024-00274-7

PMCID:: PMC11178497

Abstract Article PDF–3.9M

Select item 111320172.

HLA-B and TIMP1 as hub genes of the ventricular remodeling caused by hypertension

Gai-Feng Hu, Ling-Bing Meng, Jianyi Li, Jiapei Xu, Hong-Xuan Xu, De-Ping Liu

Aging (Albany NY) 2024 May 15; 16(9): 8260–8278. Published online 2024 May 9. doi: 10.18632/aging.205816

PMCID:: PMC11132017

Abstract Article PDF–2.6M

Select item 111094833.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 109485824.

GnT-V-mediated aberrant N-glycosylation of TIMP-1 promotes diabetic retinopathy progression

Xiaoting Xi, Yanni Yang, Qianbo Chen, Jia Ma, Xuewei Wang, Yachun Deng, Xi Wang, Yan Li

Mol Biol Rep. 2024; 51(1): 428. Published online 2024 Mar 18. doi: 10.1007/s11033-024-09388-7

PMCID:: PMC10948582

Abstract Article PDF–8.1M

Select item 108717955.

The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model

Sander van Riet, Anais Julien, Andrea Atanasov, Åsa Nordling, Magnus Ingelman-Sundberg

Hepatol Commun. 2024 Mar; 8(3): e0374. Published online 2024 Feb 14. doi: 10.1097/HC9.0000000000000374

PMCID:: PMC10871795

Abstract Article PDF–1.6M

Select item 106524646.

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival

Ezgi Ozyerli-Goknar, Ezgi Yagmur Kala, Ali Cenk Aksu, Ipek Bulut, Ahmet Cingöz, Sheikh Nizamuddin, Martin Biniossek, Fidan Seker-Polat, Tunc Morova, Can Aztekin, Sonia H. Y. Kung, Hamzah Syed, Nurcan Tuncbag, Mehmet Gönen, Martin Philpott, Adam P. Cribbs, Ceyda Acilan, Nathan A. Lack, Tamer T. Onder, H. T. Marc Timmers, Tugba Bagci-Onder

Cell Commun Signal. 2023; 21: 328. Published online 2023 Nov 16. doi: 10.1186/s12964-023-01335-6

PMCID:: PMC10652464

Abstract Article PDF–8.0M

Select item 105811947.

Upregulated TIMP1 facilitates and coordinates myometrial contraction by decreasing collagens and cell adhesive capacity during human labor

Junjie Bao, Xiaodi Wang, Lina Chen, Bolun Wen, Qiu Gao, Xiuyu Pan, Yunshan Chen, Kaiyuan Ji, Huishu Liu

Mol Hum Reprod. 2023 Oct; 29(10): gaad034. Published online 2023 Sep 29. doi: 10.1093/molehr/gaad034

PMCID:: PMC10581194

Abstract Article PDF–1.3M

Select item 105223828.

TIMP1 shapes an immunosuppressive microenvironment by regulating anoikis to promote the progression of clear cell renal cell carcinoma

Qiang Li, Kai Wei, Xi Zhang, Yang Lv, Miao Li, Chenchao Zhou, Shifeng Su, Daorong Hou, Jianquan Hou

Aging (Albany NY) 2023 Sep 15; 15(17): 8908–8929. Published online 2023 Sep 8. doi: 10.18632/aging.205005

PMCID:: PMC10522382

Abstract Article PDF–3.7M

Select item 104702909.

Proteomics Identifies Circulating TIMP-1 as a Prognostic Biomarker for Diffuse Large B-Cell Lymphoma

Ning Lou, Guibin Wang, Yanrong Wang, Meng Xu, Yu Zhou, Qiaoyun Tan, Qiaofeng Zhong, Lei Zhang, Xiaomei Zhang, Shuxia Liu, Rongrong Luo, Shasha Wang, Le Tang, Jiarui Yao, Zhishang Zhang, Yuankai Shi, Xiaobo Yu, Xiaohong Han

Mol Cell Proteomics. 2023 Sep; 22(9): 100625. Published online 2023 Jul 26. doi: 10.1016/j.mcpro.2023.100625

PMCID:: PMC10470290

Abstract Article PDF–5.1M

Select item 1039971010.

The invariant chain CD74 protein is a cell surface binding partner of TIMP‐1 in breast cancer cells

Mikkel Høeberg, Julie Boertmann Noer, Mette Vixø Vistesen, Annette Bartels, Esben Matzen Bech, Sune Boris Nygård, Ulrik Lademann, Jan Stenvang, Siqi Liu, Anja Thoe Fuglsang, Nils Brünner, José Manuel Afonso Moreira

Mol Oncol. 2023 Aug; 17(8): 1595–1612. Published online 2023 Apr 28. doi: 10.1002/1878-0261.13436

PMCID:: PMC10399710

Abstract Article PDF–7.8M

Select item 1037714611.

Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) and Pulmonary Involvement in COVID-19 Pneumonia

Maria Antonella Zingaropoli, Tiziana Latronico, Patrizia Pasculli, Giorgio Maria Masci, Roberta Merz, Federica Ciccone, Federica Dominelli, Cosmo Del Borgo, Miriam Lichtner, Franco Iafrate, Gioacchino Galardo, Francesco Pugliese, Valeria Panebianco, Paolo Ricci, Carlo Catalano, Maria Rosa Ciardi, Grazia Maria Liuzzi, Claudio Maria Mastroianni

Biomolecules. 2023 Jul; 13(7): 1040. Published online 2023 Jun 26. doi: 10.3390/biom13071040

PMCID:: PMC10377146

Abstract Article PDF–2.7M

Select item 1029185012.

CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice

Griffin A. Greco, Mitchell Rock, Matthew Amontree, Maria Fe Lanfranco, Holly Korthas, Sung Hyeok Hong, R. Scott Turner, G. William Rebeck, Katherine Conant

Neurobiol Dis. Author manuscript; available in PMC 2023 Jun 26.

Published in final edited form as: Neurobiol Dis. 2023 Apr; 179: 106057. Published online 2023 Mar 5. doi: 10.1016/j.nbd.2023.106057

PMCID:: PMC10291850

Abstract Article PDF–1.4M

Select item 986596313.

siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury

Ivan V. Chernikov, Yaroslav Yu. Staroseletz, Irina S. Tatarnikova, Aleksandra V. Sen’kova, Innokenty A. Savin, Andrey V. Markov, Evgeniya B. Logashenko, Elena L. Chernolovskaya, Marina A. Zenkova, Valentin V. Vlassov

Int J Mol Sci. 2023 Jan; 24(2): 1641. Published online 2023 Jan 13. doi: 10.3390/ijms24021641

PMCID:: PMC9865963

Abstract Article PDF–6.6M

Select item 983762614.

TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes

Celina Eckfeld, Benjamin Schoeps, Daniel Häußler, Julian Frädrich, Felix Bayerl, Jan Philipp Böttcher, Percy Knolle, Simone Heisz, Olga Prokopchuk, Hans Hauner, Enkhtsetseg Munkhbaatar, Ihsan Ekin Demir, Chris D. Hermann, Achim Krüger

J Cell Biol. 2023 Feb 6; 222(2): e202206095. Published online 2023 Jan 11. doi: 10.1083/jcb.202206095

PMCID:: PMC9837626

Abstract Article PDF–4.7M

Select item 981605915.

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou

Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x

PMCID:: PMC9816059

Abstract Article PDF–7.6M

Select item 974605616.

TIMP1 promotes cell proliferation and invasion capability of right‐sided colon cancers via the FAK/Akt signaling pathway

Beibei Ma, Hiroyuki Ueda, Koichi Okamoto, Masahiro Bando, Shota Fujimoto, Yasuyuki Okada, Tomoyuki Kawaguchi, Hironori Wada, Hiroshi Miyamoto, Mitsuo Shimada, Yasushi Sato, Tetsuji Takayama

Cancer Sci. 2022 Dec; 113(12): 4244–4257. Published online 2022 Sep 21. doi: 10.1111/cas.15567

PMCID:: PMC9746056

Abstract Article PDF–4.2M

Select item 966781517.

Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma

Paula Duch, Natalia Díaz-Valdivia, Rafael Ikemori, Marta Gabasa, Evette S. Radisky, Marselina Arshakyan, Sabrina Gea-Sorlí, Anna Mateu-Bosch, Paloma Bragado, Josep Lluís Carrasco, Hidetoshi Mori, Josep Ramírez, Cristina Teixidó, Noemí Reguart, Cristina Fillat, Derek C. Radisky, Jordi Alcaraz

Matrix Biol. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: Matrix Biol. 2022 Aug; 111: 207–225. Published online 2022 Jul 2. doi: 10.1016/j.matbio.2022.06.009

PMCID:: PMC9667815

Abstract Article PDF–2.3M

Select item 956264718.

TIMP-1 Dependent Modulation of Metabolic Profiles Impacts Chemoresistance in NSCLC

Wei Xiao, Pankaj Ahluwalia, Lan Wang, John Howard, Ravindra Kolhe, Amyn M. Rojiani, Mumtaz V. Rojiani

Cells. 2022 Oct; 11(19): 3036. Published online 2022 Sep 28. doi: 10.3390/cells11193036

PMCID:: PMC9562647

Abstract Article PDF–4.8M

Select item 952364519.

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han

Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6

PMCID:: PMC9523645

Abstract Article PDF–3.9M

Select item 949322820.

The role of tissue inhibitor of metalloproteinases in the aetiology of inguinal and incisional hernias

Ugur Durukan, Orhan Agcaoglu, Emre Ozoran, Salih Nafiz Karahan, Ibrahim Ozata, Yigit Duzkoylu, Esra Pasaoglu, Acar Aren

Int Wound J. 2022 Oct; 19(6): 1502–1508. Published online 2022 Mar 11. doi: 10.1111/iwj.13746

PMCID:: PMC9493228

Abstract Article PDF–1.2M

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