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Select item 108079331.

Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy

Gregory J. Krause, Philipp Kirchner, Barbara Stiller, Kateryna Morozova, Antonio Diaz, Kuei-Ho Chen, Nevan J. Krogan, Esperanza Agullo-Pascual, Cristina C. Clement, Kristen Lindenau, Danielle L. Swaney, Shilpa Dilipkumar, Jose Javier Bravo-Cordero, Laura Santambrogio, Ana Maria Cuervo

Cell Rep. Author manuscript; available in PMC 2024 Jan 24.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113529. Published online 2023 Dec 6. doi: 10.1016/j.celrep.2023.113529

PMCID:: PMC10807933

Abstract Article PDF–2.9M

Select item 105456732.

The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes

Dan Liu, Ruinan Xing, Quanyu Zhang, Xiaoxiang Tian, Yanping Qi, Haixu Song, Yanxia Liu, Haibo Yu, Xiaolin Zhang, Quanmin Jing, Chenghui Yan, Yaling Han

Exp Mol Med. 2023 Sep; 55(9): 2025–2038. Published online 2023 Sep 1. doi: 10.1038/s12276-023-01081-2

PMCID:: PMC10545673

Abstract Article PDF–5.6M

Select item 104391833.

Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired

Wenjing Liang, Shakti Sagar, Rishith Ravindran, Rita H. Najor, Justin M. Quiles, Liguo Chi, Rachel Y. Diao, Benjamin P. Woodall, Leonardo J. Leon, Erika Zumaya, Jason Duran, David M. Cauvi, Antonio De Maio, Eric D. Adler, Åsa B. Gustafsson

Nat Commun. 2023; 14: 5031. Published online 2023 Aug 18. doi: 10.1038/s41467-023-40680-5

PMCID:: PMC10439183

Abstract Article PDF–7.6M

Select item 102928714.

LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice

Katherine K. Zhang, Peichuan Zhang, Anagha Kodur, Ilkim Erturk, Calvin M. Burns, Cynthia Kenyon, Richard A. Miller, S. Joseph Endicott

Aging (Albany NY) 2023 Jun 15; 15(11): 4685–4698. Published online 2023 Jun 13. doi: 10.18632/aging.204796

PMCID:: PMC10292871

Abstract Article PDF–1.9M

Select item 100463255.

Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of Dab1^−/−(yotari) Mice

Mirko Maglica, Nela Kelam, Ejazul Haque, Ilija Perutina, Anita Racetin, Natalija Filipović, Yu Katsuyama, Katarina Vukojević

Biomolecules. 2023 Mar; 13(3): 402. Published online 2023 Feb 21. doi: 10.3390/biom13030402

PMCID:: PMC10046325

Abstract Article PDF–72M

Select item 98512486.

LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development

Pedro M. Rodrigues, Laura G. Sousa, Chiara Perrod, Ana R. Maceiras, Pedro Ferreirinha, Rita Pombinho, Gema Romera-Cárdenas, María Gomez-Lazaro, Meryem Senkara, Jelena Pistolic, Didier Cabanes, Ludger Klein, Paul Saftig, Nuno L. Alves

Autophagy. 2023; 19(2): 426–439. Published online 2022 May 19. doi: 10.1080/15548627.2022.2074105

PMCID:: PMC9851248

Abstract Article PDF–1.6M

Select item 93657727.

The a subunit isoforms of vacuolar-type proton ATPase exhibit differential distribution in mouse perigastrulation embryos

Ge-Hong Sun-Wada, Yoh Wada

Sci Rep. 2022; 12: 13590. Published online 2022 Aug 10. doi: 10.1038/s41598-022-18002-4

PMCID:: PMC9365772

Abstract Article PDF–2.8M

Select item 93389508.

Germline FOXJ2 overexpression causes male infertility via aberrant autophagy activation by LAMP2A upregulation

Fu-Rong Bai, Qi-Qian Wu, Yu-Jie Wu, Yan-Qin Hu, Zhi-Xuan Jiang, Hao Lv, Wen-Zhe Qian, Chang Cai, Jing-Wen Wu

Cell Death Dis. 2022 Jul; 13(7): 665. Published online 2022 Jul 30. doi: 10.1038/s41419-022-05116-w

PMCID:: PMC9338950

Abstract Article PDF–6.8M

Select item 89931199.

Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction

Kimberlee P. Giffen, Yi Li, Huizhan Liu, Xiao-Chang Zhao, Chang-Jun Zhang, Ren-Juan Shen, Tianying Wang, Amanda Janesick, Bo-Bei Chen, Shu-Sheng Gong, Bechara Kachar, Zi-Bing Jin, David Z. He

Sci Adv. 2022 Apr; 8(14): eabk0942. Published online 2022 Apr 8. doi: 10.1126/sciadv.abk0942

PMCID:: PMC8993119

Abstract Article PDF–6.6M

Select item 891735510.

Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

Gianna M. Fote, Nicolette R. Geller, Nikolaos E. Efstathiou, Nathan Hendricks, Demetrios G. Vavvas, Jack C. Reidling, Leslie M. Thompson, Joan S. Steffan

J Cell Sci. 2022 Jan 15; 135(2): jcs258687. Published online 2022 Jan 25. doi: 10.1242/jcs.258687

PMCID:: PMC8917355

Abstract Article

Select item 887321611.

Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass

Nisreen Akel, Ryan S. MacLeod, Stuart B. Berryhill, Dominique J. Laster, Milena Dimori, Julie A. Crawford, Qiang Fu, Melda Onal

Sci Rep. 2022; 12: 3134. Published online 2022 Feb 24. doi: 10.1038/s41598-022-07157-9

PMCID:: PMC8873216

Abstract Article PDF–2.4M

Select item 876221212.

Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure

Ling Zeng, Jinzhao Zhou, Yanwei Zhang, Xiaofei Wang, Mei Wang, Ping Su

Front Cell Dev Biol. 2021; 9: 791784. Published online 2022 Jan 3. doi: 10.3389/fcell.2021.791784

PMCID:: PMC8762212

Abstract Article PDF–3.9M

Select item 872661613.

Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells

Kazue Terasawa, Yuji Kato, Yuta Ikami, Kensaku Sakamoto, Kazumasa Ohtake, Seisuke Kusano, Yuri Tomabechi, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Jun-Lin Guan, Toshihide Kobayashi, Takanori Iwata, Tetsuro Watabe, Shigeyuki Yokoyama, Miki Hara-Yokoyama

Autophagy. 2021; 17(12): 4286–4304. Published online 2021 Apr 14. doi: 10.1080/15548627.2021.1911017

PMCID:: PMC8726616

Abstract Article PDF–5.9M

Select item 872660814.

CREG1 promotes lysosomal biogenesis and function

Jie Liu, Yanmei Qi, Joshua Chao, Pranav Sathuvalli, Leonard Y. Lee, Shaohua Li

Autophagy. 2021; 17(12): 4249–4265. Published online 2021 May 8. doi: 10.1080/15548627.2021.1909997

PMCID:: PMC8726608

Abstract Article PDF–9.2M

Select item 868825215.

Reciprocal regulation of chaperone-mediated autophagy and the circadian clock

Yves R. Juste, Susmita Kaushik, Mathieu Bourdenx, Ranee Aflakpui, Sanmay Bandyopadhyay, Fernando Garcia, Antonio Diaz, Kristen Lindenau, Vincent Tu, Gregory J. Krause, Maryam Jafari, Rajat Singh, Javier Muñoz, Fernando Macian, Ana Maria Cuervo

Nat Cell Biol. Author manuscript; available in PMC 2022 Jun 7.

Published in final edited form as: Nat Cell Biol. 2021 Dec; 23(12): 1255–1270. Published online 2021 Dec 7. doi: 10.1038/s41556-021-00800-z

PMCID:: PMC8688252

Abstract Article PDF–7.4M

Select item 864927716.

LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart

Ronny Alcalai, Michael Arad, Hiroko Wakimoto, Dor Yadin, Joshua Gorham, Libin Wang, Elia Burns, Barry J. Maron, William C. Roberts, Tetsuo Konno, David A. Conner, Antonio R. Perez‐Atayde, Jon G. Seidman, Christine E. Seidman

J Am Heart Assoc. 2021 Sep 7; 10(17): e018829. Published online 2021 Aug 28. doi: 10.1161/JAHA.120.018829