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Items: 1 to 20 of 21

1.
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8
PMCID:
PMC10499821
AbstractArticlePDF–2.6M
2.
Inhibition of Cholinergic Signaling Causes Apoptosis in Human Bronchioalveolar Carcinoma
Jamie K. Lau, Kathleen C. Brown, Brent A. Thornhill, Clayton M. Crabtree, Aaron M. Dom, Theodore R. Witte, W. Elaine Hardman, Christopher A. McNees, Cody A. Stover, A. Betts Carpenter, Haitao Luo, Yi C. Chen, Brandon S. Shiflett, Piyali Dasgupta
Cancer Res. Author manuscript; available in PMC 2023 Aug 28.
Published in final edited form as: Cancer Res. 2013 Feb 15; 73(4): 1328–1339. Published online 2012 Dec 7. doi: 10.1158/0008-5472.CAN-12-3190
PMCID:
PMC10461321
AbstractArticlePDF–2.6M
3.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
4.
Phenotypical and Myopathological Consequences of Compound Heterozygous Missense and Nonsense Variants in SLC18A3
Adela Della Marina, Annabelle Arlt, Ulrike Schara-Schmidt, Christel Depienne, Andrea Gangfuß, Heike Kölbel, Albert Sickmann, Erik Freier, Nicolai Kohlschmidt, Andreas Hentschel, Joachim Weis, Artur Czech, Anika Grüneboom, Andreas Roos
Cells. 2021 Dec; 10(12): 3481. Published online 2021 Dec 9. doi: 10.3390/cells10123481
PMCID:
PMC8700530
AbstractArticlePDF–6.0M
5.
Variants of SLC18A3 leading to congenital myasthenic syndrome in two children with varying presentations
Allison Lamond, David Buckley, Jennifer O'Dea, Lesley Turner
BMJ Case Rep. 2021; 14(1): e237799. Published online 2021 Jan 18. doi: 10.1136/bcr-2020-237799
PMCID:
PMC7813295
AbstractArticlePDF–188K
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
Regional Vesicular Acetylcholine Transporter Distribution in Human Brain: A [18F]Fluoroethoxybenzovesamicol Positron Emission Tomography Study
Roger L. Albin, Nicolaas I. Bohnen, Martijn LT Muller, William T. Dauer, Martin Sarter, Kirk A. Frey, Robert A. Koeppe
J Comp Neurol. Author manuscript; available in PMC 2019 Nov 4.
Published in final edited form as: J Comp Neurol. 2018 Dec 1; 526(17): 2884–2897. Published online 2018 Oct 19. doi: 10.1002/cne.24541
PMCID:
PMC6827569
AbstractArticlePDF–2.5M
8.
Cholinergic system changes of falls and freezing of gait in Parkinson's disease
Nicolaas I. Bohnen, Prabesh Kanel, Zhi Zhou, Robert A. Koeppe, Kirk A. Frey, William T. Dauer, Roger L. Albin, Martijn L.T.M. Müller
Ann Neurol. 2019 Apr; 85(4): 538–549. Published online 2019 Mar 13. doi: 10.1002/ana.25430
PMCID:
PMC6450746
AbstractArticlePDF–698K
9.
LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells
Philipp Trepte, Sabrina Kruse, Simona Kostova, Sheila Hoffmann, Alexander Buntru, Anne Tempelmeier, Christopher Secker, Lisa Diez, Aline Schulz, Konrad Klockmeier, Martina Zenkner, Sabrina Golusik, Kirstin Rau, Sigrid Schnoegl, Craig C Garner, Erich E Wanker
Mol Syst Biol. 2018 Jul; 14(7): e8071. Published online 2018 Jul 11. doi: 10.15252/msb.20178071
PMCID:
PMC6039870
AbstractArticlePDF–2.1M
10.
Vesicular acetylcholine transporter defect underlies devastating congenital myasthenia syndrome
Adi Aran, Reeval Segel, Kota Kaneshige, Suleyman Gulsuner, Paul Renbaum, Scott Oliphant, Tomer Meirson, Ariella Weinberg-Shukron, Yair Hershkovitz, Sharon Zeligson, Ming K. Lee, Abraham O. Samson, Stanley M. Parsons, Mary-Claire King, Ephrat Levy-Lahad, Tom Walsh
Neurology. 2017 Mar 14; 88(11): 1021–1028. doi: 10.1212/WNL.0000000000003720
PMCID:
PMC5384838
AbstractArticlePDF–670K
11.
Identification of a mammalian vesicular polyamine transporter
Miki Hiasa, Takaaki Miyaji, Yuka Haruna, Tomoya Takeuchi, Yuika Harada, Sawako Moriyama, Akitsugu Yamamoto, Hiroshi Omote, Yoshinori Moriyama
Sci Rep. 2014; 4: 6836. Published online 2014 Oct 30. doi: 10.1038/srep06836
PMCID:
PMC4213795
AbstractArticlePDF–2.6M
12.
Recurrent Deletions and Reciprocal Duplications of 10q11.21q11.23 Including CHAT and SLC18A3 are Likely Mediated by Complex Low-Copy Repeats
Paweł Stankiewicz, Shashikant Kulkarni, Avinash V. Dharmadhikari, Srirangan Sampath, Samarth S. Bhatt, Tamim H. Shaikh, Zhilian Xia, Amber N. Pursley, M. Lance Cooper, Marwan Shinawi, Alex R. Paciorkowski, Dorothy K. Grange, Michael J. Noetzel, Scott Saunders, Paul Simons, Marshall Summar, Brendan Lee, Fernando Scaglia, Florence Fellmann, Danielle Martinet, Jacques S. Beckmann, Alexander Asamoah, Kathryn Platky, Susan Sparks, Ann S. Martin, Suneeta Madan-Khetarpal, Jacqueline Hoover, Livija Medne, Carsten G. Bonnemann, John B. Moeschler, Stephanie E. Vallee, Sumit Parikh, Polly Irwin, Victoria P. Dalzell, Wendy E. Smith, Valerie C. Banks, David B. Flannery, Carolyn M. Lovell, Gary A. Bellus, Kathryn Golden-Grant, Jerome L. Gorski, Jennifer L. Kussmann, Tracy L. McGregor, Rizwan Hamid, Jean Pfotenhauer, Blake C. Ballif, Chad A. Shaw, Sung-Hae L. Kang, Carlos A. Bacino, Ankita Patel, Jill A. Rosenfeld, Sau Wai Cheung, Lisa G. Shaffer
Hum Mutat. Author manuscript; available in PMC 2013 May 16.
Published in final edited form as: Hum Mutat. 2012 Jan; 33(1): 165–179. Published online 2011 Nov 2. doi: 10.1002/humu.21614
PMCID:
PMC3655525
AbstractArticlePDF–4.3M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Nuclear Choline Acetyltransferase Activates Transcription of a High-affinity Choline Transporter
Akinori Matsuo, Jean-Pierre Bellier, Masaki Nishimura, Osamu Yasuhara, Naoaki Saito, Hiroshi Kimura
J Biol Chem. 2011 Feb 18; 286(7): 5836–5845. Published online 2010 Dec 16. doi: 10.1074/jbc.M110.147611
PMCID:
PMC3037696
AbstractArticlePDF–2.1M
15.
Search for the acetylcholine and vesamicol binding sites in vesicular acetylcholine transporter: the region around the lumenal end of the transport channel
Parul Khare, Anuprao Mulakaluri, Stanley M. Parsons
J Neurochem. Author manuscript; available in PMC 2011 Nov 1.
Published in final edited form as: J Neurochem. 2010 Nov; 115(4): 984–993. Published online 2010 Oct 12. doi: 10.1111/j.1471-4159.2010.06990.x
PMCID:
PMC2962730
AbstractArticlePDF–678K
16.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
17.
Possible important pair of acidic residues in vesicular acetylcholine transporter
Parul Khare, Ana M. Ojeda, Ananda Chandrasekaran, Stanley M. Parsons
Biochemistry. Author manuscript; available in PMC 2011 Apr 13.
Published in final edited form as: Biochemistry. 2010 Apr 13; 49(14): 3049–3059. doi: 10.1021/bi901953j
PMCID:
PMC2875949
AbstractArticlePDF–1.2M
18.
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer’s disease
J Chapuis, D Hot, F Hansmannel, O Kerdraon, S Ferreira, C Hubans, CA Maurage, L Huot, F Bensemain, G Laumet, AM Ayral, N Fievet, JJ Hauw, ST DeKosky, Y Lemoine, T Iwatsubo, F Wavrant-Devrièze, JF Dartigues, C Tzourio, L Buée, F Pasquier, C Berr, D Mann, C Lendon, A Alpérovitch, MI Kamboh, P Amouyel, JC Lambert
Mol Psychiatry. Author manuscript; available in PMC 2010 Apr 28.
Published in final edited form as: Mol Psychiatry. 2009 Nov; 14(11): 1004–1016. Published online 2009 Feb 10. doi: 10.1038/mp.2009.10
PMCID:
PMC2860783
AbstractArticlePDF–1.3M
19.
Multiple Protonation States of Vesicular Acetylcholine Transporter Detected by Binding of [3H]Vesamicol
Parul Khare, Aubrey R. White, Stanley M. Parsons
Biochemistry. Author manuscript; available in PMC 2009 Dec 14.
Published in final edited form as: Biochemistry. 2009 Sep 29; 48(38): 8965–8975. doi: 10.1021/bi900759v
PMCID:
PMC2793091
AbstractArticlePDF–1.2M
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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