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Select item 111940931.

Proximal telomeric decompaction due to telomere shortening drives FOXC1-dependent myocardial senescence

Bin Li, Weiyao Xiong, Wu Zuo, Yuanyuan Shi, Teng Wang, Lingling Chang, Yueheng Wu, Heng Ma, Qian Bian, Alex C Y Chang

Nucleic Acids Res. 2024 Jun 24; 52(11): 6269–6284. Published online 2024 Apr 18. doi: 10.1093/nar/gkae274

PMCID:: PMC11194093

Abstract Article PDF–2.7M

Select item 109597742.

Reciprocal regulation of forkhead box C1 and L1 cell adhesion molecule contributes to triple-negative breast cancer progression

Fan Zhang, Yue Xu, Jiediao Lin, Hongchao Pan, Armando E. Giuliano, Xiaojiang Cui, Yukun Cui

Breast Cancer Res Treat. 2024; 204(3): 465–474. Published online 2024 Jan 6. doi: 10.1007/s10549-023-07177-7

PMCID:: PMC10959774

Abstract Article PDF–1.7M

Select item 101516153.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 97080864.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 95878525.

Clinical Significance of MAP-7 and FOXC1 in Egyptian Acute Myeloid Leukemia Patients

Safa Mohamed Nabawy, Lobna Ahmed Refaat, Hussam Mohamed Naser Aldin, Reham A Rashed

Asian Pac J Cancer Prev. 2022 May; 23(5): 1619–1626. doi: 10.31557/APJCP.2022.23.5.1619

PMCID:: PMC9587852

Abstract Article PDF–454K

Select item 95403456.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 94349877.

FOXC1-mediated TRIM22 regulates the excessive proliferation and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis via NF-κB signaling pathway

Yazhi Wei, Xinmin Huang, Yanmei Ma, Liping Dai

Mol Med Rep. 2022 Oct; 26(4): 304. Published online 2022 Aug 9. doi: 10.3892/mmr.2022.12820

PMCID:: PMC9434987

Abstract Article PDF–6.2M

Select item 93902278.

Comparison of Anterior Segment Abnormalities in Individuals With FOXC1 and PITX2 Variants

Mallika Prem Senthil, Lachlan S. W. Knight, Deepa Taranath, David A. Mackey, Jonathan B. Ruddle, Mark Y. Chiang, Owen M. Siggs, Emmanuelle Souzeau, Jamie E. Craig

Cornea. 2022 Aug; 41(8): 1009–1015. Published online 2022 Mar 30. doi: 10.1097/ICO.0000000000003020

PMCID:: PMC9390227

Abstract Article PDF–198K

Select item 92902419.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Abstract Article PDF–8.2M

Select item 906515510.

Somatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia

Yaping Wang, Xiaopeng Ma, Jie Huang, Xiaoyun Yang, Meiyun Kang, Xiaoyan Sun, Huimin Li, Yijun Wu, Heng Zhang, Yuting Zhu, Yao Xue, Yongjun Fang

Cell Death Dis. 2022 May; 13(5): 431. Published online 2022 May 3. doi: 10.1038/s41419-022-04873-y

PMCID:: PMC9065155

Abstract Article PDF–8.1M

Select item 894907611.

Variable Anterior Segment Dysgenesis and Cardiac Anomalies Caused by a Novel Truncating Variant of FOXC1

Mariya R. Ahmed, Saumil Sethna, Laura A. Krueger, Michael B. Yang, Robert B. Hufnagel

Genes (Basel) 2022 Mar; 13(3): 411. Published online 2022 Feb 24. doi: 10.3390/genes13030411

PMCID:: PMC8949076

Abstract Article PDF–26M

Select item 882889512.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 880653713.

MicroRNA miR-106a-5p targets forkhead box transcription factor FOXC1 to suppress the cell proliferation, migration, and invasion of ectopic endometrial stromal cells via the PI3K/Akt/mTOR signaling pathway

Xinyue Zhou, Zhenyu Chen, Lipeng Pei, Jingli Sun

Bioengineered. 2021; 12(1): 2203–2213. Published online 2021 Jun 4. doi: 10.1080/21655979.2021.1933679

PMCID:: PMC8806537

Abstract Article PDF–2.7M

Select item 870974814.

miR-149 Suppresses the Proliferation and Metastasis of Human Gastric Cancer Cells by Targeting FOXC1

Dan Li, Yunqing Zhang, Yulong Li, Xiaofei Wang, Fenghui Wang, Juan Du, Huahua Zhang, Haiyan Shi, Yanfeng Wang, Yi Gao, Yun Feng, Jing Yan, Yajuan Xue, Yang Yang, Jing Zhang

Biomed Res Int. 2021; 2021: 1503403. Published online 2021 Dec 17. doi: 10.1155/2021/1503403

PMCID:: PMC8709748

Abstract Article PDF–3.4M

Select item 855290715.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 851636016.

A novel tumour suppressor protein encoded by circMAPK14 inhibits progression and metastasis of colorectal cancer by competitively binding to MKK6

Lu Wang, Jiahui Zhou, Chuan Zhang, Ranran Chen, Qingyang Sun, Peng Yang, Chaofan Peng, Yuqian Tan, Chi Jin, Tuo Wang, Jiangzhou Ji, Yueming Sun

Clin Transl Med. 2021 Oct; 11(10): e613. Published online 2021 Oct 14. doi: 10.1002/ctm2.613

PMCID:: PMC8516360

Abstract Article PDF–5.6M

Select item 848028117.

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia

Fabrizio Simeoni, Isabel Romero-Camarero, Francesco Camera, Fabio M.R. Amaral, Oliver J. Sinclair, Evangelia K. Papachristou, Gary J. Spencer, Michael Lie-A-Ling, Georges Lacaud, Daniel H. Wiseman, Jason S. Carroll, Tim C.P. Somervaille

Cell Rep. 2021 Sep 21; 36(12): 109725. Published online 2021 Sep 21. doi: 10.1016/j.celrep.2021.109725

PMCID:: PMC8480281

Abstract Article

Select item 838765318.

干扰FOXC1逆转非小细胞肺癌吉非替尼耐药的作用

彭聪, 李盼, 杨明强, 陈丹扬, 黄渊锋

Zhongguo Fei Ai Za Zhi. 2021 Aug 20; 24(8): 538–547. Chinese. doi: 10.3779/j.issn.1009-3419.2021.103.11

PMCID:: PMC8387653

Abstract Article PDF–9.7M

Select item 825964519.

Super-Enhancer-Associated Transcription Factors Maintain Transcriptional Regulation in Mature Podocytes

Jingping Yang, Difei Zhang, Masaru Motojima, Tsutomu Kume, Qing Hou, Yu Pan, Aiping Duan, Mingchao Zhang, Song Jiang, Jinhua Hou, Jingsong Shi, Zhaohui Qin, Zhihong Liu

J Am Soc Nephrol. 2021 Jun; 32(6): 1323–1337. Published online 2021 Jun 1. doi: 10.1681/ASN.2020081177

PMCID:: PMC8259645

Abstract Article

Select item 822040720.

Phenotype expansion of heterozygous FOXC1 pathogenic variants toward involvement of congenital anomalies of the kidneys and urinary tract (CAKUT)

Chen-Han Wilfred Wu, Nina Mann, Makiko Nakayama, Dervla M. Connaughton, Rufeng Dai, Caroline M. Kolvenbach, Franziska Kause, Isabel Ottlewski, Chunyan Wang, Verena Klämbt, Steve Seltzsam, Ethan W. Lai, Aravind Selvin, Prabha Senguttuva, Olaf Bodamer, Deborah R. Stein, Sherif El Desoky, Jameela A. Kari, Velibor Tasic, Stuart B. Bauer, Shirlee Shril, Friedhelm Hildebrandt

Genet Med. Author manuscript; available in PMC 2021 Jun 23.

Published in final edited form as: Genet Med. 2020 Oct; 22(10): 1673–1681. Published online 2020 Jun 1. doi: 10.1038/s41436-020-0844-z

PMCID:: PMC8220407

Abstract Article PDF–995K

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In vitro differentiated amniotic-fluid kidney progenitor cell-podocytes
In vitro differentiated amniotic-fluid kidney progenitor cell-podocytes
Accession: GDS5028

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Serca2a effect on Dilated Cardiomyopathy iPSC-derived cardiomyocytes
Serca2a effect on Dilated Cardiomyopathy iPSC-derived cardiomyocytes
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