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Select item 109525801.

Exploring bias in platelet P2Y₁ signalling: Host defence versus haemostasis

Dingxin Pan, Graham Ladds, Khondaker Miraz Rahman, Simon C. Pitchford

Br J Pharmacol. 2024 Feb; 181(4): 580–592. Published online 2023 Aug 2. doi: 10.1111/bph.16191

PMCID:: PMC10952580

Abstract Article PDF–1.6M

Select item 107927532.

Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics

Arnaud Dance, Justine Fernandes, Bénédicte Toussaint, Emmanuel Vaillant, Raphaël Boutry, Morgane Baron, Hélène Loiselle, Beverley Balkau, Guillaume Charpentier, Sylvia Franc, Mark Ibberson, Michel Marre, Marie Gernay, Marjorie Fadeur, Nicolas Paquot, Martine Vaxillaire, Mathilde Boissel, Souhila Amanzougarene, Mehdi Derhourhi, Amna Khamis, Philippe Froguel, Amélie Bonnefond

Mol Metab. 2024 Jan; 79: 101867. Published online 2023 Dec 28. doi: 10.1016/j.molmet.2023.101867

PMCID:: PMC10792753

Abstract Article PDF–1.6M

Select item 98678623.

Association between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation

Chunyan Su, Zhishan Zhang, Jintu Chen, Mengcha Tian, Conglian Wu, Tao Zhang

BMC Cardiovasc Disord. 2023; 23: 41. Published online 2023 Jan 21. doi: 10.1186/s12872-023-03075-4

PMCID:: PMC9867862

Abstract Article PDF–767K

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78271925.

Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy

Juan Carlos Gil-Redondo, Jagoba Iturri, Felipe Ortega, Raquel Pérez-Sen, Andreas Weber, María Teresa Miras-Portugal, José Luis Toca-Herrera, Esmerilda G. Delicado

Int J Mol Sci. 2021 Jan; 22(2): 624. Published online 2021 Jan 10. doi: 10.3390/ijms22020624

PMCID:: PMC7827192

Abstract Article PDF–3.3M

Select item 74327586.

Contribution of P2X4 Receptors to CNS Function and Pathophysiology

Alejandro Montilla, Gilda Paloma Mata, Carlos Matute, Maria Domercq

Int J Mol Sci. 2020 Aug; 21(15): 5562. Published online 2020 Aug 3. doi: 10.3390/ijms21155562

PMCID:: PMC7432758

Abstract Article PDF–624K

Select item 66355417.

Autocrine stimulation of P2Y1 receptors is part of the purinergic signaling mechanism that regulates T cell activation

Tobias Woehrle, Carola Ledderose, Jessica Rink, Christian Slubowski, Wolfgang G. Junger

Purinergic Signal. 2019 Jun; 15(2): 127–137. Published online 2019 Mar 27. doi: 10.1007/s11302-019-09653-6

PMCID:: PMC6635541

Abstract Article PDF–2.1M

Select item 64362148.

The TXA2R rs1131882, P2Y1 rs1371097 and GPIIIa rs2317676 three-loci interactions may increase the risk of carotid stenosis in patients with ischemic stroke

Xingyang Yi, Jing Lin, Qiang Zhou, Ruyue Huang, Zhenxiao Chai

BMC Neurol. 2019; 19: 44. Published online 2019 Mar 26. doi: 10.1186/s12883-019-1271-0

PMCID:: PMC6436214

Abstract Article PDF–576K

Select item 57512809.

Population-Specific Associations of Deleterious Rare Variants in Coding Region of P2RY1–P2RY12 Purinergic Receptor Genes in Large-Vessel Ischemic Stroke Patients

Piotr K. Janicki, Ceren Eyileten, Victor Ruiz-Velasco, Khaled Anwar Sedeek, Justyna Pordzik, Anna Czlonkowska, Iwona Kurkowska-Jastrzebska, Shigekazu Sugino, Yuka Imamura-Kawasawa, Dagmara Mirowska-Guzel, Marek Postula

Int J Mol Sci. 2017 Dec; 18(12): 2678. Published online 2017 Dec 11. doi: 10.3390/ijms18122678

PMCID:: PMC5751280

Abstract Article PDF–719K

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 535674311.

Pin1 induces the ADP-induced migration of human dental pulp cells through P2Y1 stabilization

Soo-A Kim, Hong Seok Choi, Sang-Gun Ahn

Oncotarget. 2016 Dec 20; 7(51): 85381–85392. Published online 2016 Nov 16. doi: 10.18632/oncotarget.13377

PMCID:: PMC5356743

Abstract Article PDF–6.0M

Select item 535051612.

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins

Hemant B. Badgandi, Sun-hee Hwang, Issei S. Shimada, Evan Loriot, Saikat Mukhopadhyay

J Cell Biol. 2017 Mar 6; 216(3): 743–760. doi: 10.1083/jcb.201607095

PMCID:: PMC5350516

Abstract Article PDF–3.1M

Select item 522358013.

Interaction among COX-2, P2Y1 and GPIIIa gene variants is associated with aspirin resistance and early neurological deterioration in Chinese stroke patients

Xingyang Yi, Chun Wang, Qiang Zhou, Jing Lin

BMC Neurol. 2017; 17: 4. Published online 2017 Jan 9. doi: 10.1186/s12883-016-0788-8

PMCID:: PMC5223580

Abstract Article PDF–412K

Select item 508294914.

P2Y₁ Receptor Signaling Contributes to High Salt-Induced Priming of the NLRP3 Inflammasome in Retinal Pigment Epithelial Cells

Philipp Prager, Margrit Hollborn, Anja Steffen, Peter Wiedemann, Leon Kohen, Andreas Bringmann

PLoS One. 2016; 11(10): e0165653. Published online 2016 Oct 27. doi: 10.1371/journal.pone.0165653

PMCID:: PMC5082949

Abstract Article PDF–4.7M

Select item 502362715.

Coupling switch of P2Y-IP₃ receptors mediates differential Ca²⁺ signaling in human embryonic stem cells and derived cardiovascular progenitor cells

Jijun Huang, Min Zhang, Peng Zhang, He Liang, Kunfu Ouyang, Huang-Tian Yang

Purinergic Signal. 2016 Sep; 12(3): 465–478. Published online 2016 Apr 20. doi: 10.1007/s11302-016-9512-9

PMCID:: PMC5023627

Abstract Article PDF–4.9M

Select item 490747616.

ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y₁ Purinergic Receptor via a YPX₃L Motif

Michael R. Dores, Neil J. Grimsey, Francisco Mendez, JoAnn Trejo

PLoS One. 2016; 11(6): e0157587. Published online 2016 Jun 14. doi: 10.1371/journal.pone.0157587

PMCID:: PMC4907476

Abstract Article PDF–3.4M

Select item 476759617.

Synergistic inhibition of both P2Y₁ and P2Y₁₂ adenosine diphosphate receptors as novel approach to rapidly attenuate platelet-mediated thrombosis

Thomas Gremmel, Ivan B. Yanachkov, Milka I. Yanachkova, George E. Wright, Joseph Wider, Vishnu V.R. Undyala, Alan D. Michelson, Andrew L. Frelinger, III, Karin Przyklenk

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3): 501–509. Published online 2016 Jan 7. doi: 10.1161/ATVBAHA.115.306885