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Select item 112084981.

miR-124-3p downregulates EGR1 to suppress ischemia-hypoxia reperfusion injury in human iPS cell-derived cardiomyocytes

Qiaoke Yang, Kozue Murata, Tadashi Ikeda, Kenji Minatoya, Hidetoshi Masumoto

Sci Rep. 2024; 14: 14811. Published online 2024 Jun 27. doi: 10.1038/s41598-024-65373-x

PMCID:: PMC11208498

Abstract Article PDF–5.8M

Select item 111582692.

Early growth response‐1 mediates downregulation of telomerase in cervical cancer

Osamu Akutagawa, Hirotaka Nishi, Satoru Kyo, Fumitoshi Terauchi, Koji Yamazawa, Chinatsu Higuma, Masaki Inoue, Keiichi Isaka

Cancer Sci. 2008 Jul; 99(7): 1401–1406. Published online 2008 May 2. doi: 10.1111/j.1349-7006.2008.00835.x

PMCID:: PMC11158269

Abstract Article PDF–256K

Select item 108781423.

Blocking EGR1/TGF-β1 and CD44s/STAT3 Crosstalk Inhibits Peritoneal Metastasis of Gastric Cancer

Yangbing Jin, Chao Wang, Benyan Zhang, Ying Sun, Jun Ji, Qu Cai, Jinling Jiang, Zhihao Zhang, Liqin Zhao, Beiqin Yu, Jun Zhang

Int J Biol Sci. 2024; 20(4): 1314–1331. Published online 2024 Jan 27. doi: 10.7150/ijbs.90598

PMCID:: PMC10878142

Abstract Article PDF–12M

Select item 108237304.

EGR1 suppresses HCC growth and aerobic glycolysis by transcriptionally downregulating PFKL

Mingang Pan, Muyu Luo, Lele Liu, Yunmeng Chen, Ziyi Cheng, Kai Wang, Luyi Huang, Ni Tang, Jianguo Qiu, Ailong Huang, Jie Xia

J Exp Clin Cancer Res. 2024; 43: 35. Published online 2024 Jan 29. doi: 10.1186/s13046-024-02957-5

PMCID:: PMC10823730

Abstract Article PDF–4.8M

Select item 107953285.

Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli

Ruicheng Yang, Xinyi Wang, Hulin Liu, Jiaqi Chen, Chen Tan, Huanchun Chen, Xiangru Wang

Cell Commun Signal. 2024; 22: 44. Published online 2024 Jan 17. doi: 10.1186/s12964-024-01488-y

PMCID:: PMC10795328

Abstract Article PDF–11M

Select item 107867176.

Tumor-mesothelium HOXA11-PDGF BB/TGF β1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer

Chao Wang, Jun Ji, Yangbing Jin, Ying Sun, Qu Cai, Jinling Jiang, Liting Guo, Chenfei Zhou, Jun Zhang

Oncogene. 2024; 43(3): 171–188. Published online 2023 Nov 21. doi: 10.1038/s41388-023-02891-4

PMCID:: PMC10786717

Abstract Article PDF–9.3M

Select item 106539947.

EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8

Yinghua Zhao, Liyan Sui, Ping Wu, Letian Li, Li Liu, Baohua Ma, Wenfang Wang, Hongmiao Chi, Ze-Dong Wang, Zhengkai Wei, Zhijun Hou, Kaiyu Zhang, Junqi Niu, Ningyi Jin, Chang Li, Jixue Zhao, Guoqing Wang, Quan Liu

J Virol. 2023 Oct; 97(10): e01028-23. Published online 2023 Sep 29. doi: 10.1128/jvi.01028-23

PMCID:: PMC10653994

Abstract Article PDF–4.2M

Select item 106176738.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105917739.

EGR1/LINC00839/SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells

Zunxian Wang, Bo Wei, Shuxia Ma

Cancer Biol Ther. 2023; 24(1): 2270106. Published online 2023 Oct 20. doi: 10.1080/15384047.2023.2270106

PMCID:: PMC10591773

Abstract Article PDF–4.9M

Select item 1056587610.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1053232711.

EGR1 Regulation of Vasculogenic Mimicry in the MDA-MB-231 Triple-Negative Breast Cancer Cell Line through the Upregulation of KLF4 Expression

Euitaek Jung, Young Han Lee, Sukjin Ou, Tae Yoon Kim, Soon Young Shin

Int J Mol Sci. 2023 Sep; 24(18): 14375. Published online 2023 Sep 21. doi: 10.3390/ijms241814375

PMCID:: PMC10532327

Abstract Article PDF–4.2M

Select item 1051760012.

EGR1 Promotes Ovarian Hyperstimulation Syndrome Through Upregulation of SOX9 Expression

Huihui Wang, Weijia Chen, Yinan Huang, Yuan Sun, Yuanhua Liu, Yuanchao Zhu, Zongxuan Lu

Cell Transplant. 2023 Jan-Dec; 32: 09636897231193073. Published online 2023 Sep 22. doi: 10.1177/09636897231193073

PMCID:: PMC10517600

Abstract Article PDF–1.7M

Select item 1051116413.

Role of early growth response 1 in inflammation-associated lung diseases

Kang Zou, Zhenguo Zeng

Am J Physiol Lung Cell Mol Physiol. 2023 Aug 1; 325(2): L143–L154. Published online 2023 Jul 4. doi: 10.1152/ajplung.00413.2022

PMCID:: PMC10511164

Abstract Article

Select item 1018192914.

N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21^cip1/waf1/CDK2-Cyclin E1 axis-mediated cell cycle transition

Rui Liu, Jiyu Miao, Yachun Jia, Guangyao Kong, Fei Hong, Fangmei Li, Meng Zhai, Ru Zhang, Jiaxi Liu, Xuezhu Xu, Ting Wang, Hui Liu, Jinsong Hu, Yun Yang, Aili He

Oncogene. 2023; 42(20): 1607–1619. Published online 2023 Apr 3. doi: 10.1038/s41388-023-02675-w

PMCID:: PMC10181929

Abstract Article PDF–6.7M

Select item 999471115.

EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation

Marcella Cesana, Gennaro Tufano, Francesco Panariello, Nicolina Zampelli, Susanna Ambrosio, Rossella De Cegli, Margherita Mutarelli, Lorenzo Vaccaro, Micheal J. Ziller, Davide Cacchiarelli, Diego L. Medina, Andrea Ballabio

PLoS Biol. 2023 Mar; 21(3): e3002034. Published online 2023 Mar 8. doi: 10.1371/journal.pbio.3002034

PMCID:: PMC9994711

Abstract Article PDF–2.3M

Select item 991266416.

GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1

Brooke A. Marks, Ilissa M. Pipia, Chinatsu Mukai, Sachi Horibata, Edward J. Rice, Charles G. Danko, Scott A. Coonrod

BMC Cancer. 2023; 23: 138. Published online 2023 Feb 10. doi: 10.1186/s12885-023-10559-1

PMCID:: PMC9912664

Abstract Article PDF–1.9M

Select item 985197317.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0