PMC Links for GEO Profiles (Select 120947701) - PMC

Select item 105206341.

The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus

Fang Zhang, Baokai Zhang, Huihua Ding, Xiangyue Li, Xilin Wang, Xiaomin Zhang, Qiaojie Liu, Qiuyun Feng, Mingshun Han, Longlong Chen, Linlin Qi, Dan Yang, Xiaojing Li, Xingguo Zhu, Qi Zhao, Jiaqian Qiu, Zhengjiang Zhu, Huiru Tang, Nan Shen, Hongyan Wang, Bin Wei

Adv Sci (Weinh) 2023 Sep; 10(27): 2207108. Published online 2023 Jul 19. doi: 10.1002/advs.202207108

PMCID:: PMC10520634

Abstract Article PDF–8.9M

Select item 89647002.

EBI2 is a negative modulator of brown adipose tissue energy expenditure in mice and human brown adipocytes

Francesca Copperi, Inna Schleis, Martin Roumain, Giulio G. Muccioli, Stefano Casola, Martin Klingenspor, Alexander Pfeifer, Thorsten Gnad

Commun Biol. 2022; 5: 280. Published online 2022 Mar 29. doi: 10.1038/s42003-022-03201-6

PMCID:: PMC8964700

Abstract Article PDF–1.8M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76775844.

GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease Severity

Stacey Bartlett, Adrian Tandhyka Gemiarto, Minh Dao Ngo, Haressh Sajiir, Semira Hailu, Roma Sinha, Cheng Xiang Foo, Léanie Kleynhans, Happy Tshivhula, Tariq Webber, Helle Bielefeldt-Ohmann, Nicholas P. West, Andriette M. Hiemstra, Candice E. MacDonald, Liv von Voss Christensen, Larry S. Schlesinger, Gerhard Walzl, Mette Marie Rosenkilde, Thomas Mandrup-Poulsen, Katharina Ronacher

Front Immunol. 2020; 11: 601534. Published online 2020 Nov 6. doi: 10.3389/fimmu.2020.601534

PMCID:: PMC7677584

Abstract Article PDF–1.8M

Select item 55316115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 54769106.

Epstein-Barr Virus–induced Gene 2 Mediates Allergen-induced Leukocyte Migration into Airways

Zhong-Jian Shen, Jie Hu, Venkatesh P. Kashi, Elizabeth A. Kelly, Loren C. Denlinger, Kevan Lutchman, Jeffrey G. McDonald, Nizar N. Jarjour, James S. Malter

Am J Respir Crit Care Med. 2017 Jun 15; 195(12): 1576–1585. Published online 2017 Jun 15. doi: 10.1164/rccm.201608-1580OC

PMCID:: PMC5476910

Abstract Article PDF–850K

Select item 53148127.

EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia–like B-cell malignancies

Kristine Niss Arfelt, Line Barington, Tau Benned-Jensen, Valentina Kubale, Alexander L. Kovalchuk, Viktorija Daugvilaite, Jan Pravsgaard Christensen, Allan Randrup Thomsen, Kristoffer L. Egerod, Maria R. Bassi, Katja Spiess, Thue W. Schwartz, Hongsheng Wang, Herbert C. Morse, III, Peter J. Holst, Mette M. Rosenkilde

Blood. 2017 Feb 16; 129(7): 866–878. Prepublished online 2016 Dec 21. doi: 10.1182/blood-2016-02-697185

PMCID:: PMC5314812

Abstract Article

Select item 46172118.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 42976239.

Oxysterols direct immune cell migration through EBI2

Sébastien Hannedouche, Juan Zhang, Tangsheng Yi, Weijun Shen, Deborah Nguyen, João P. Pereira, Danilo Guerini, Birgit U. Baumgarten, Silvio Roggo, Ben Wen, Richard Knochenmuss, Sophie Noël, Francois Gessier, Lisa M. Kelly, Mirka Vanek, Stephane Laurent, Inga Preuss, Charlotte Miault, Isabelle Christen, Ratna Karuna, Wei Li, Dong-In Koo, Thomas Suply, Christian Schmedt, Eric C. Peters, Rocco Falchetto, Andreas Katopodis, Carsten Spanka, Marie-Odile Roy, Michel Detheux, Yu Alice Chen, Peter G. Schultz, Charles Y. Cho, Klaus Seuwen, Jason G. Cyster, Andreas W. Sailer

Nature. Author manuscript; available in PMC 2015 Jan 18.

Published in final edited form as: Nature. 2011 Jul 28; 475(7357): 524–527. Published online 2011 Jul 27. doi: 10.1038/nature10280

PMCID:: PMC4297623

Abstract Article PDF–1.3M

Select item 374165910.

Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression

Kathryn E. Hulse, James E. Norton, Lydia Suh, Qiu Zhong, Mahboobeh Mahdavinia, Patrick Simon, Robert C. Kern, David B. Conley, Rakesh K. Chandra, Bruce K. Tan, Anju T. Peters, Leslie C. Grammer, III, Kathleen E. Harris, Roderick G. Carter, Atsushi Kato, Robert P. Schleimer

J Allergy Clin Immunol. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: J Allergy Clin Immunol. 2013 Apr; 131(4): 1075–1083.e7. Published online 2013 Mar 6. doi: 10.1016/j.jaci.2013.01.043

PMCID:: PMC3741659

Abstract Article PDF–3.0M

Select item 358276911.

CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression

Dong Young Kim, Eunju Kwon, Paul D. Hartley, David C. Crosby, Sumanjit Mann, Nevan J. Krogan, John D. Gross

Mol Cell. Author manuscript; available in PMC 2014 Feb 21.

Published in final edited form as: Mol Cell. 2013 Feb 21; 49(4): 632–644. Published online 2013 Jan 17. doi: 10.1016/j.molcel.2012.12.012

PMCID:: PMC3582769

Abstract Article PDF–4.5M

Select item 349180312.

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho

Nature. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582

PMCID:: PMC3491803

Abstract Article PDF–706K

Select item 347168613.

Molecular Characterization of Oxysterol Binding to the Epstein-Barr Virus-induced Gene 2 (GPR183)

Tau Benned-Jensen, Christoffer Norn, Stephane Laurent, Christian M. Madsen, Hjalte M. Larsen, Kristine N. Arfelt, Romain M. Wolf, Thomas Frimurer, Andreas W. Sailer, Mette M. Rosenkilde

J Biol Chem. 2012 Oct 12; 287(42): 35470–35483. Published online 2012 Aug 8. doi: 10.1074/jbc.M112.387894

PMCID:: PMC3471686

Abstract Article PDF–2.8M

Select item 319073514.

Ligand Modulation of the Epstein-Barr Virus-induced Seven-transmembrane Receptor EBI2: IDENTIFICATION OF A POTENT AND EFFICACIOUS INVERSE AGONIST

Tau Benned-Jensen, Christopher Smethurst, Peter J. Holst, Kevin R. Page, Howard Sauls, Bjørn Sivertsen, Thue W. Schwartz, Andy Blanchard, Robert Jepras, Mette M. Rosenkilde

J Biol Chem. 2011 Aug 19; 286(33): 29292–29302. Published online 2011 Jun 14. doi: 10.1074/jbc.M110.196345