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Items: 1 to 20 of 50

1.
lincRNA00907 promotes NASH progression by targeting miRNA-942-5p/TAOK1
Gang Du, Zhaochen Jiang, Tong Xia, Mingkun Liu, Zeyang Liu, Huaxin Zhou, Hao Zhang, Xiangyu Zhai, Bin Jin
Aging (Albany NY) 2024 Apr 30; 16(8): 6868–6882. Published online 2024 Apr 10. doi: 10.18632/aging.205730
PMCID:
PMC11087098
AbstractArticlePDF–2.3M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
4.
Silencing of STE20-type kinase TAOK1 confers protection against hepatocellular lipotoxicity through metabolic rewiring
Ying Xia, Emma Andersson, Sumit K. Anand, Emmelie Cansby, Mara Caputo, Sima Kumari, Rando Porosk, Kalle Kilk, Syam Nair, Hanns-Ulrich Marschall, Matthias Blüher, Margit Mahlapuu
Hepatol Commun. 2023 Apr; 7(4): e0037. Published online 2023 Mar 17. doi: 10.1097/HC9.0000000000000037
PMCID:
PMC10027040
AbstractArticlePDF–2.2M
5.
FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia
Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen
J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0
PMCID:
PMC9922468
AbstractArticlePDF–4.9M
6.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
7.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
8.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
9.
Lessons learned from multifaceted diagnostic approaches to the first 150 families in Victoria’s Undiagnosed Diseases Program
Thomas Cloney, Lyndon Gallacher, Lynn Pais, Natalie B. Tan, Alison Yeung, Zornitza Stark, Natasha J Brown, George McGillivray, Martin B Delatycki, Michelle G. de Silva, Lilian Downie, Chloe A. Stutterd, Justine Elliott, Alison G. Compton, Alysia Lovgren, Ralph Oertel, David Francis, Katrina Bell, Simon Sadedin, Sze Chern Lim, Guy Helman, Cas Simons, Daniel G. MacArthur, David R Thorburn, Anne O’Donnell-Luria, John Christodoulou, Susan M. White, Tiong Yang Tan
J Med Genet. Author manuscript; available in PMC 2022 Aug 1.
Published in final edited form as: J Med Genet. 2022 Aug; 59(8): 748–758. Published online 2021 Nov 5. doi: 10.1136/jmedgenet-2021-107902
PMCID:
PMC9068835
AbstractArticlePDF–657K
10.
The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1
Han Han, Hiroki J Nakaoka, Line Hofmann, Jeff Jiajing Zhou, Clinton Yu, Lisha Zeng, Junyu Nan, Gayoung Seo, Rebecca Elizabeth Vargas, Bing Yang, Ruxi Qi, Lee Bardwell, Dmitry A. Fishman, Ken W.Y. Cho, Lan Huang, Ray Luo, Rahul Warrior, Wenqi Wang
Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.
Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 74–87. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00813-8
PMCID:
PMC9022944
AbstractArticlePDF–8.9M
11.
Inherited and de novo variants extend the etiology of TAOK1-associated neurodevelopmental disorder
Jesse M. Hunter, Lauren J. Massingham, Kandamurugu Manickam, Dennis Bartholomew, Rachel K. Williamson, Jennifer L. Schwab, Mohammad Marhabaie, Amy Siemon, Emily de los Reyes, Shalini C. Reshmi, Catherine E. Cottrell, Richard K. Wilson, Daniel C. Koboldt
Cold Spring Harb Mol Case Stud. 2022 Feb; 8(2): a006180. doi: 10.1101/mcs.a006180
PMCID:
PMC8958914
AbstractArticlePDF–3.5M
12.
TAOK1 is associated with neurodevelopmental disorder and essential for neuronal maturation and cortical development
Geeske M. van Woerden, Melanie Bos, Charlotte de Konink, Ben Distel, Rossella Avagliano Trezza, Natasha E. Shur, Kristin Barañano, Sonal Mahida, Anna Chassevent, Allison Schreiber, Angelika L. Erwin, Karen W. Gripp, Fatima Rehman, Saskia Brulleman, Róisín McCormack, Gwynna de Geus, Louisa Kalsner, Arthur Sorlin, Ange‐Line Bruel, David A. Koolen, Melissa K. Gabriel, Mari Rossi, David R. Fitzpatrick, Andrew O.M. Wilkie, Eduardo Calpena, David Johnson, Alice Brooks, Marjon van Slegtenhorst, Julie Fleischer, Daniel Groepper, Kristin Lindstrom, A. Micheil Innes, Allison Goodwin, Jennifer Humberson, Amanda Noyes, Katherine G. Langley, Aida Telegrafi, Amy Blevins, Jessica Hoffman, Maria J. Guillen Sacoto, Jane Juusola, Kristin G. Monaghan, Sumit Punj, Marleen Simon, Rolph Pfundt, Ype Elgersma, Tjitske Kleefstra
Hum Mutat. 2021 Apr; 42(4): 445–459. Published online 2021 Mar 1. doi: 10.1002/humu.24176
PMCID:
PMC8248425
AbstractArticlePDF–7.4M
13.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
14.
FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2
Fei Xu, Jiajia Li, Mengdong Ni, Jingyi Cheng, Haiyun Zhao, Shanshan Wang, Xiang Zhou, Xiaohua Wu
Mol Cancer. 2021; 20: 45. Published online 2021 Mar 3. doi: 10.1186/s12943-021-01340-8
PMCID:
PMC7927415
AbstractArticlePDF–2.9M
15.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
16.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
17.
The interactome of the prostate-specific protein Anoctamin 7
Elina Kaikkonen, Aliisa Takala, Juha-Pekka Pursiheimo, Gudrun Wahlström, Johanna Schleutker
Cancer Biomark. 2020; 28(1): 91–100. Prepublished online 2020 Mar 6. Published online 2020 Apr 30. doi: 10.3233/CBM-190993
PMCID:
PMC7306890
AbstractArticlePDF–2.2M
18.
De Novo Variants in TAOK1 Cause Neurodevelopmental Disorders
Marija Dulovic-Mahlow, Joanne Trinh, Krishna Kumar Kandaswamy, Geir Julius Braathen, Nataliya Di Donato, Elisa Rahikkala, Skadi Beblo, Martin Werber, Victor Krajka, Øyvind L. Busk, Hauke Baumann, Nouriya Abbas Al-Sannaa, Frauke Hinrichs, Rabea Affan, Nir Navot, Mohammed A. Al Balwi, Gabriela Oprea, Øystein L. Holla, Maximilian E.R. Weiss, Rami A. Jamra, Anne-Karin Kahlert, Shivendra Kishore, Kristian Tveten, Melissa Vos, Arndt Rolfs, Katja Lohmann
Am J Hum Genet. 2019 Jul 3; 105(1): 213–220. Published online 2019 Jun 20. doi: 10.1016/j.ajhg.2019.05.005
PMCID:
PMC6612514
AbstractArticlePDF–1020K
19.
BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression
Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-François Rual, James Douglas Engel
Genes Dev. 2018 Dec 1; 32(23-24): 1537–1549. doi: 10.1101/gad.318436.118
PMCID:
PMC6295165
AbstractArticlePDF–3.5M
20.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M

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