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Select item 109315021.

CD38 promotes hematopoietic stem cell dormancy

Liliia Ibneeva, Sumeet Pal Singh, Anupam Sinha, Sema Elif Eski, Rebekka Wehner, Luise Rupp, Iryna Kovtun, Juan Alberto Pérez-Valencia, Alexander Gerbaulet, Susanne Reinhardt, Manja Wobus, Malte von Bonin, Jaime Sancho, Frances Lund, Andreas Dahl, Marc Schmitz, Martin Bornhäuser, Triantafyllos Chavakis, Ben Wielockx, Tatyana Grinenko

PLoS Biol. 2024 Feb; 22(2): e3002517. Published online 2024 Feb 29. doi: 10.1371/journal.pbio.3002517

PMCID:: PMC10931502

Abstract Article PDF–3.7M

Select item 108311082.

CD38 genetic variation is associated with increased personal distress to an emotional stimulus

Tanya L. Procyshyn, Laury-Ann Leclerc Bédard, Bernard J. Crespi, Jennifer A. Bartz

Sci Rep. 2024; 14: 2571. Published online 2024 Jan 31. doi: 10.1038/s41598-024-53081-5

PMCID:: PMC10831108

Abstract Article PDF–875K

Select item 108287653.

Frequent, high density expression of surface CD38 as a potential therapeutic target in adult T-lineage acute lymphoblastic leukemia

Sebastian Koslowski, Rainer Glauben, Stefan Habringer, Thomas Burmeister, Ulrich Keller, Monika Brüggemann, Nicola Gökbuget, Stefan Schwartz

Haematologica. 2024 Feb 1; 109(2): 661–665. Published online 2023 Sep 7. doi: 10.3324/haematol.2023.283814

PMCID:: PMC10828765

Article PDF–2.8M

Select item 106985404.

Acquired CD38 gene deletion as a mechanism of tumor antigen escape in multiple myeloma

Andrew J. Portuguese, Min Fang, Sherilyn A. Tuazon, Margot Pont, Xiaoyu Qu, Carolyn Shasha, Melissa Comstock, Justina Lyons, Gabriel Cole, Evan W. Newell, Emily Glynn, Lorinda A. Soma, Damian J. Green

Blood Adv. 2023 Dec 12; 7(23): 7235–7238. Published online 2023 Oct 18. doi: 10.1182/bloodadvances.2023011295

PMCID:: PMC10698540

Article PDF–2.0M

Select item 106076755.

Prognostic Impact of CD38- and IgκC-Positive Tumor-Infiltrating Plasma Cells in Triple-Negative Breast Cancer

Anne-Sophie Heimes, Natali Riedel, Katrin Almstedt, Slavomir Krajnak, Roxana Schwab, Kathrin Stewen, Antje Lebrecht, Marco Johannes Battista, Walburgis Brenner, Annette Hasenburg, Marcus Schmidt

Int J Mol Sci. 2023 Oct; 24(20): 15219. Published online 2023 Oct 16. doi: 10.3390/ijms242015219

PMCID:: PMC10607675

Abstract Article PDF–1.2M

Select item 105922156.

A Population of Tumor-Infiltrating CD4+ T-cells Co-expressing CD38 and CD39 is Associated with Checkpoint Inhibitor Resistance

Ankita Mitra, Brian Thompson, Ann Strange, Carol M. Amato, Melinda Vassallo, Igor Dolgalev, Jonathan Hester-McCullough, Tomoaki Muramatsu, Diana Kimono, Amrutesh S. Puranik, Jeffrey S. Weber, David Woods

Clin Cancer Res. Author manuscript; available in PMC 2024 Apr 13.

Published in final edited form as: Clin Cancer Res. 2023 Oct 13; 29(20): 4242–4255. doi: 10.1158/1078-0432.CCR-23-0653

PMCID:: PMC10592215

Abstract Article PDF–3.0M

Select item 105570567.

Clonally expanded CD38^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis

Runci Wang, Anvita Singaraju, Kathryne E. Marks, Lorien Shakib, Garrett Dunlap, Ifeoluwakiisi Adejoorin, Stinne R. Greisen, Lin Chen, Aidan K. Tirpack, Carlos Aude, Miriam R. Fein, Derrick J. Todd, Lindsey MacFarlane, Susan M. Goodman, Edward F. DiCarlo, Elena M. Massarotti, Jeffrey A. Sparks, A. Helena Jonsson, Michael B. Brenner, Michael A. Postow, Karmela K. Chan, Anne R. Bass, Laura T. Donlin, Deepak A. Rao

Sci Immunol. Author manuscript; available in PMC 2023 Oct 6.

Published in final edited form as: Sci Immunol. 2023 Jul 28; 8(85): eadd1591. Published online 2023 Jul 28. doi: 10.1126/sciimmunol.add1591

PMCID:: PMC10557056

Abstract Article PDF–2.3M

Select item 104404748.

CD38 as a pan-hematologic target for chimeric antigen receptor T cells

Tina Glisovic-Aplenc, Caroline Diorio, John A. Chukinas, Kimberly Veliz, Olga Shestova, Feng Shen, Selene Nunez-Cruz, Tiffaney L. Vincent, Fei Miao, Michael C. Milone, Carl H. June, David T. Teachey, Sarah K. Tasian, Richard Aplenc, Saar Gill

Blood Adv. 2023 Aug 22; 7(16): 4418–4430. Published online 2023 May 12. doi: 10.1182/bloodadvances.2022007059

PMCID:: PMC10440474

Abstract Article PDF–2.6M

Select item 104052029.

Cytokine receptor IL27RA is an NF-κB–responsive gene involved in CD38 upregulation in multiple myeloma

Rebecca J. Brownlie, Ruth Kennedy, Erica B. Wilson, Maja Milanovic, Claire F. Taylor, Dapeng Wang, John R. Davies, Heather Owston, Emma J. Adams, Sophie Stephenson, Rebecca Caeser, Benjamin E. Gewurz, Peter V. Giannoudis, Claudio Scuoppo, Dennis McGonagle, Daniel J. Hodson, Reuben M. Tooze, Gina M. Doody, Gordon Cook, David R. Westhead, Ulf Klein

Blood Adv. 2023 Aug 8; 7(15): 3874–3890. Published online 2023 Mar 8. doi: 10.1182/bloodadvances.2022009044

PMCID:: PMC10405202

Abstract Article PDF–1.8M

Select item 1038746710.

Mass cytometry uncovers a distinct peripheral immune profile and upregulated CD38 expression in patients with hidradenitis suppurativa

Peter Dimitrion, Iltefat Hamzavi, Congcong Yin, Jugmohit Toor, Kalpana Subedi, Namir Khalasawi, Angela Miller, Richard Huggins, Indra Adrianto, Jesse Veenstra, Gautham Vellaichamy, Aakash Hans, Steven Daveluy, Mohammad Athar, Wilson Liao, Henry Lim, David Ozog, Li Zhou, Qing-Sheng Mi

Cell Mol Immunol. 2023 Aug; 20(8): 972–975. Published online 2023 May 29. doi: 10.1038/s41423-023-01037-6

PMCID:: PMC10387467

Article PDF–1.1M

Select item 1017246611.

CD38: an ecto-enzyme with functional diversity in T cells

Alip Ghosh, Arshi Khanam, Krishanu Ray, Poonam Mathur, Ananya Subramanian, Bhawna Poonia, Shyam Kottilil

Front Immunol. 2023; 14: 1146791. Published online 2023 Apr 27. doi: 10.3389/fimmu.2023.1146791

PMCID:: PMC10172466

Abstract Article PDF–10M

Select item 1002528312.

Comprehensive Proteomics Analysis Identifies CD38-Mediated NAD⁺ Decline Orchestrating Renal Fibrosis in Pediatric Patients With Obstructive Nephropathy

Yuandong Tao, Jifeng Wang, Xuexue Lyu, Na Li, Dong Lai, Yuanyuan Liu, Xingyue Zhang, Pin Li, Shouqing Cao, Xiaoguang Zhou, Yang Zhao, Lifei Ma, Tian Tao, Zhichun Feng, Xiubin Li, Fuquan Yang, Huixia Zhou

Mol Cell Proteomics. 2023 Mar; 22(3): 100510. Published online 2023 Feb 17. doi: 10.1016/j.mcpro.2023.100510

PMCID:: PMC10025283

Abstract Article PDF–8.8M

Select item 995449613.

The Role of CD38 in the Pathogenesis of Cardiorenal Metabolic Disease and Aging, an Approach from Basic Research

Munehiro Kitada, Shin-ichi Araki, Daisuke Koya

Cells. 2023 Feb; 12(4): 595. Published online 2023 Feb 12. doi: 10.3390/cells12040595

PMCID:: PMC9954496

Abstract Article PDF–1.7M

Select item 992598814.

Mechanism of CD38 via NAD⁺ in the Development of Non-alcoholic Fatty Liver Disease

Min Dong, Shuo Wang, Zuowei Pei

Int J Med Sci. 2023; 20(2): 262–266. Published online 2023 Jan 22. doi: 10.7150/ijms.81381

PMCID:: PMC9925988

Abstract Article PDF–778K

Select item 973393715.

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos

Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437

PMCID:: PMC9733937

Abstract Article PDF–2.2M

Select item 928019316.

Human CD38 regulates B cell antigen receptor dynamic organization in normal and malignant B cells

Alessandro Camponeschi, Kathrin Kläsener, Timothy Sundell, Christina Lundqvist, Paul T. Manna, Negar Ayoubzadeh, Martina Sundqvist, Katrin Thorarinsdottir, Mariele Gatto, Marcella Visentini, Karin Önnheim, Alaitz Aranburu, Huamei Forsman, Olov Ekwall, Linda Fogelstrand, Inger Gjertsson, Michael Reth, Inga-Lill Mårtensson

J Exp Med. 2022 Sep 5; 219(9): e20220201. Published online 2022 Jul 12. doi: 10.1084/jem.20220201

PMCID:: PMC9280193

Abstract Article PDF–4.3M

Select item 908112217.

CD38 plays an age-related role in cholinergic deregulation of airway smooth muscle contractility

Yan Bai, Alonso G. P. Guedes, Ramaswamy Krishnan, Xingbin Ai

J Allergy Clin Immunol. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: J Allergy Clin Immunol. 2022 May; 149(5): 1643–1654.e8. Published online 2021 Nov 18. doi: 10.1016/j.jaci.2021.10.033

PMCID:: PMC9081122

Abstract Article PDF–1.5M

Select item 865880418.

Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-N1-inosine 5′-monophosphate, Analogues and Early Structure-Activity Relationship

Joanna M. Watt, Richard Graeff, Barry V. L. Potter

Molecules. 2021 Dec; 26(23): 7165. Published online 2021 Nov 26. doi: 10.3390/molecules26237165

PMCID:: PMC8658804

Abstract Article PDF–2.2M

Select item 857114019.

CD38 identifies pre-activated CD8+ T cells which can be reinvigorated by anti-PD-1 blockade in human lung cancer

Pin Wu, Lufeng Zhao, Yongyuan Chen, Zhongwei Xin, Mingjie Lin, Zhixing Hao, Xiaoke Chen, Di Chen, Dang Wu, Ying Chai

Cancer Immunol Immunother. 2021 Dec; 70(12): 3603–3616. Published online 2021 May 2. doi: 10.1007/s00262-021-02949-w

PMCID:: PMC8571140

Abstract Article PDF–8.3M

Select item 846683520.

Intermittent Hypoxia Upregulates the Renin and Cd38 mRNAs in Renin-Producing Cells via the Downregulation of miR-203

Yoshinori Takeda, Asako Itaya-Hironaka, Akiyo Yamauchi, Mai Makino, Sumiyo Sakuramoto-Tsuchida, Hiroyo Ota, Ryuji Kawaguchi, Shin Takasawa

Int J Mol Sci. 2021 Sep; 22(18): 10127. Published online 2021 Sep 19. doi: 10.3390/ijms221810127

PMCID:: PMC8466835

Abstract Article PDF–2.6M

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