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Select item 110148701.

Non‐canonical IKB kinases regulate YAP/TAZ and pathological vascular remodeling behaviors in pulmonary artery smooth muscle cells

Aja Aravamudhan, Paul B. Dieffenbach, Kyoung Moo Choi, Patrick A. Link, Jeffrey A. Meridew, Andrew J. Haak, Laura E. Fredenburgh, Daniel J. Tschumperlin

Physiol Rep. 2024 Apr; 12(7): e15999. Published online 2024 Apr 12. doi: 10.14814/phy2.15999

PMCID:: PMC11014870

Abstract Article PDF–2.4M

Select item 108588452.

Tankyrase inhibition interferes with junction remodeling, induces leakiness, and disturbs YAP1/TAZ signaling in the endothelium

Nan Ma, Yohanes Cakrapradipta Wibowo, Phillip Wirtz, Doris Baltus, Thomas Wieland, Sepp Jansen

Naunyn Schmiedebergs Arch Pharmacol. 2024; 397(3): 1763–1789. Published online 2023 Sep 23. doi: 10.1007/s00210-023-02720-1

PMCID:: PMC10858845

Abstract Article PDF–9.4M

Select item 107017683.

TAZ facilitates breast tumor growth by promoting an immune‐suppressive tumor microenvironment

Anat Gershoni, Ori Hassin, Nishanth Belugali Nataraj, Sivan Baruch, Adi Avioz‐Seligman, Anna Chiara Pirona, Liat Fellus‐Alyagor, Tomer Meir Salame, Saptaparna Mukherjee, Giuseppe Mallel, Yosef Yarden, Yael Aylon, Moshe Oren

Mol Oncol. 2023 Dec; 17(12): 2675–2693. Published online 2023 Oct 16. doi: 10.1002/1878-0261.13525

PMCID:: PMC10701768

Abstract Article PDF–2.0M

Select item 106302544.

The role of the FSGS disease gene product and nuclear pore protein NUP205 in regulating nuclear localization and activity of transcriptional regulators YAP and TAZ

Lioba Ester, Inês Cabrita, Michel Ventzke, Emilia Kieckhöfer, Marita Christodoulou, Amrei M Mandel, Paul Diefenhardt, Francesca Fabretti, Thomas Benzing, Sandra Habbig, Bernhard Schermer

Hum Mol Genet. 2023 Nov 15; 32(22): 3153–3165. Published online 2023 Aug 11. doi: 10.1093/hmg/ddad135

PMCID:: PMC10630254

Abstract Article PDF–1.9M

Select item 106298155.

Epithelial Yap/Taz are required for functional alveolar regeneration following acute lung injury

Gianluca T. DiGiovanni, Wei Han, Taylor P. Sherrill, Chase J. Taylor, David S. Nichols, Natalie M. Geis, Ujjal K. Singha, Carla L. Calvi, A. Scott McCall, Molly M. Dixon, Yang Liu, Ji-Hoon Jang, Sergey S. Gutor, Vasiliy V. Polosukhin, Timothy S. Blackwell, Jonathan A. Kropski, Jason J. Gokey

JCI Insight. 2023 Oct 9; 8(19): e173374. Published online 2023 Sep 7. doi: 10.1172/jci.insight.173374

PMCID:: PMC10629815

Abstract Article PDF–3.2M

Select item 105982596.

TAZ upregulates MIR‐224 to inhibit oxidative stress response in multiple myeloma

Samuel O. Abegunde, Stacy Grieve, Tony Reiman

Cancer Rep (Hoboken) 2023 Oct; 6(10): e1879. Published online 2023 Aug 4. doi: 10.1002/cnr2.1879

PMCID:: PMC10598259

Abstract Article PDF–2.8M

Select item 101548527.

Feedforward loop between IMP1 and YAP/TAZ promotes tumorigenesis and malignant progression in glioblastoma

Jia Yang, Xujia Wu, Jia Wang, Xing Guo, Junju Chen, Xuesong Yang, Jian Zhong, Xixi Li, Zhong Deng

Cancer Sci. 2023 May; 114(5): 2053–2062. Published online 2023 Mar 1. doi: 10.1111/cas.15636

PMCID:: PMC10154852

Abstract Article PDF–23M

Select item 98996298.

YAP/TAZ activation predicts clinical outcomes in mesothelioma and is conserved in in vitro model of driver mutations

Richard Cunningham, Siyang Jia, Krishna Purohit, Omar Salem, Ning Sze Hui, Yue Lin, Neil O. Carragher, Carsten Gram Hansen

Clin Transl Med. 2023 Feb; 13(2): e1190. Published online 2023 Feb 5. doi: 10.1002/ctm2.1190

PMCID:: PMC9899629

Abstract Article PDF–3.4M

Select item 98982879.

USP15 promotes pulmonary vascular remodeling in pulmonary hypertension in a YAP1/TAZ-dependent manner

Zhuhua Wu, Li Zhu, Xinran Nie, Li Wei, Yong Qi

Exp Mol Med. 2023 Jan; 55(1): 183–195. Published online 2023 Jan 12. doi: 10.1038/s12276-022-00920-y

PMCID:: PMC9898287

Abstract Article PDF–7.1M

Select item 988346410.

A self-amplifying USP14-TAZ loop drives the progression and liver metastasis of pancreatic ductal adenocarcinoma

Chunle Zhao, Jun Gong, Yu Bai, Taoyuan Yin, Min Zhou, Shutao Pan, Yuhui Liu, Yang Gao, Zhenxiong Zhang, Yongkang Shi, Feng Zhu, Hang Zhang, Min Wang, Renyi Qin

Cell Death Differ. 2023 Jan; 30(1): 1–15. Published online 2022 Jul 29. doi: 10.1038/s41418-022-01040-w

PMCID:: PMC9883464

Abstract Article PDF–9.7M

Select item 984273511.

Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation

Xinwei Liu, Yingying Ye, Liling Zhu, Xiaoyun Xiao, Boxuan Zhou, Yuanting Gu, Hang Si, Huixin Liang, Mingzhu Liu, Jiaqian Li, Qiongchao Jiang, Jiang Li, Shubin Yu, Ruiying Ma, Shicheng Su, Jian-You Liao, Qiyi Zhao

Nat Commun. 2023; 14: 238. Published online 2023 Jan 16. doi: 10.1038/s41467-023-35856-y

PMCID:: PMC9842735

Abstract Article PDF–7.8M

Select item 935143512.

A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis

Namrata Bora-Singhal, Biswarup Saha, Durairaj Mohankumar, Jaya Padmanabhan, Domenico Coppola, Srikumar Chellappan

Cancer Res Commun. 2022 Jul; 2(7): 624–638. Published online 2022 Jul 12. doi: 10.1158/2767-9764.CRC-21-0084

PMCID:: PMC9351435

Abstract Article PDF–13M

Select item 927514213.

DUB1 suppresses Hippo signaling by modulating TAZ protein expression in gastric cancer

Dehai Wang, Zhongbo Li, Xin Li, Cheng Yan, Huijie Yang, Ting Zhuang, Xiao Wang, Yifeng Zang, Ziping Liu, Tianshi Wang, Rixia Jiang, Peng Su, Jian Zhu, Yinlu Ding

J Exp Clin Cancer Res. 2022; 41: 219. Published online 2022 Jul 12. doi: 10.1186/s13046-022-02410-5

PMCID:: PMC9275142

Abstract Article PDF–6.8M

Select item 917800714.

N-oleoylethanolamide treatment of lymphoblasts deficient in Tafazzin improves cell growth and mitochondrial morphology and dynamics

John Z. Chan, Maria F. Fernandes, Klaudia E. Steckel, Ryan M. Bradley, Ashkan Hashemi, Mishi R. Groh, German Sciaini, Ken D. Stark, Robin E. Duncan

Sci Rep. 2022; 12: 9466. Published online 2022 Jun 8. doi: 10.1038/s41598-022-13463-z

PMCID:: PMC9178007

Abstract Article PDF–3.0M

Select item 913491215.

USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ

Putao Yuan, Zhenhua Feng, Hai Huang, Gangliang Wang, Zhijun Chen, Guang Xu, Ziang Xie, Zhiwei Jie, Xiangde Zhao, Qingliang Ma, Shiyu Wang, Yang Shen, Yizhen Huang, Ying Han, Huali Ye, Jiying Wang, Peihua Shi, Xuewu Sun

Int J Biol Sci. 2022; 18(8): 3122–3136. Published online 2022 May 1. doi: 10.7150/ijbs.65428

PMCID:: PMC9134912

Abstract Article PDF–3.0M

Select item 899475116.

USP26 promotes anaplastic thyroid cancer progression by stabilizing TAZ

Jianing Tang, Yongwen Luo, Liang Xiao

Cell Death Dis. 2022 Apr; 13(4): 326. Published online 2022 Apr 9. doi: 10.1038/s41419-022-04781-1

PMCID:: PMC8994751

Abstract Article PDF–3.3M

Select item 884216517.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 872789418.

Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression

Meijia Qian, Fangjie Yan, Weihua Wang, Jiamin Du, Tao Yuan, Ruilin Wu, Chenxi Zhao, Jiao Wang, Jiabin Lu, Bo Zhang, Nengming Lin, Xin Dong, Xiaoyang Dai, Xiaowu Dong, Bo Yang, Hong Zhu, Qiaojun He

Acta Pharm Sin B. 2021 Dec; 11(12): 4008–4019. Published online 2021 Jun 25. doi: 10.1016/j.apsb.2021.04.003