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Items: 1 to 20 of 22

1.
Dynamic phosphorylation of CENP-N by CDK1 guides accurate chromosome segregation in mitosis
Ran Liu, Zhen Dou, Tian Tian, Xinjiao Gao, Lili Chen, Xiao Yuan, Chunyue Wang, Jiahe Hao, Ping Gui, McKay Mullen, Felix Aikhionbare, Liwen Niu, Guoqiang Bi, Peng Zou, Xuan Zhang, Chuanhai Fu, Xuebiao Yao, Jianye Zang, Xing Liu
J Mol Cell Biol. 2023 Jun; 15(6): mjad041. Published online 2023 Jun 26. doi: 10.1093/jmcb/mjad041
PMCID:
PMC10799313
AbstractArticlePDF–1.4M
2.
Clinical implications and immune features of CENPN in breast cancer
Zhengwei Gui, Yao Tian, Tianyao Yu, Shiyang Liu, Chenguang Liu, Lin Zhang
BMC Cancer. 2023; 23: 851. Published online 2023 Sep 11. doi: 10.1186/s12885-023-11376-2
PMCID:
PMC10496242
AbstractArticlePDF–7.3M
3.
Structural insights into human CCAN complex assembled onto DNA
Tian Tian, Lili Chen, Zhen Dou, Zhisen Yang, Xinjiao Gao, Xiao Yuan, Chengliang Wang, Ran Liu, Zuojun Shen, Ping Gui, Maikun Teng, Xianlei Meng, Donald L. Hill, Lin Li, Xuan Zhang, Xing Liu, Linfeng Sun, Jianye Zang, Xuebiao Yao
Cell Discov. 2022; 8: 90. Published online 2022 Sep 9. doi: 10.1038/s41421-022-00439-6
PMCID:
PMC9463443
AbstractArticlePDF–5.7M
4.
CENP-N promotes the compaction of centromeric chromatin
Keda Zhou, Magdalena Gebala, Dustin Woods, Kousik Sundararajan, Garrett Edwards, Dan Krzizike, Jeff Wereszczynski, Aaron F. Straight, Karolin Luger
Nat Struct Mol Biol. 2022; 29(4): 403–413. Published online 2022 Apr 14. doi: 10.1038/s41594-022-00758-y
PMCID:
PMC9010303
AbstractArticlePDF–11M
5.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance
Matthew F Pech, Linda E Fong, Jacqueline E Villalta, Leanne JG Chan, Samir Kharbanda, Jonathon J O'Brien, Fiona E McAllister, Ari J Firestone, Calvin H Jan, Jeffrey Settleman
eLife. 2019; 8: e47362. Published online 2019 Aug 27. doi: 10.7554/eLife.47362
PMCID:
PMC6713475
AbstractArticlePDF–4.6M
10.
Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N
Sagar Chittori, Jingjun Hong, Hayden Saunders, Hanqiao Feng, Rodolfo Ghirlando, Alexander E. Kelly, Yawen Bai, Sriram Subramaniam
Science. Author manuscript; available in PMC 2018 Dec 13.
Published in final edited form as: Science. 2018 Jan 19; 359(6373): 339–343. Published online 2017 Dec 21. doi: 10.1126/science.aar2781
PMCID:
PMC6292214
AbstractArticlePDF–1.7M
11.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
12.
Constitutive centromere-associated network contacts confer differential stability on CENP-A nucleosomes in vitro and in the cell
Shengya Cao, Keda Zhou, Zhening Zhang, Karolin Luger, Aaron F. Straight
Mol Biol Cell. 2018 Mar 15; 29(6): 751–762. doi: 10.1091/mbc.E17-10-0596
PMCID:
PMC6003232
AbstractArticlePDF–577K
13.
Decoding the centromeric nucleosome through CENP-N
Satyakrishna Pentakota, Keda Zhou, Charlotte Smith, Stefano Maffini, Arsen Petrovic, Garry P Morgan, John R Weir, Ingrid R Vetter, Andrea Musacchio, Karolin Luger
eLife. 2017; 6: e33442. Published online 2017 Dec 27. doi: 10.7554/eLife.33442
PMCID:
PMC5777823
AbstractArticlePDF–6.9M
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
The CENP-L-N complex forms a critical node in an integrated meshwork of interactions at the centromere-kinetochore interface
Kara L. McKinley, Nikolina Sekulic, Lucie Y. Guo, Tonia Tsinman, Ben E. Black, Iain M. Cheeseman
Mol Cell. Author manuscript; available in PMC 2016 Dec 17.
Published in final edited form as: Mol Cell. 2015 Dec 17; 60(6): 886–898. Published online 2015 Nov 19. doi: 10.1016/j.molcel.2015.10.027
PMCID:
PMC4690846
AbstractArticlePDF–1.5M
16.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
17.
A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint
Daniel R. Matson, Pinar B. Demirel, P. Todd Stukenberg, Daniel J. Burke
Genes Dev. 2012 Mar 15; 26(6): 542–547. doi: 10.1101/gad.184184.111
PMCID:
PMC3315115
AbstractArticlePDF–1.1M
18.
Dynamics of CENP-N kinetochore binding during the cell cycle
Daniela Hellwig, Stephan Emmerth, Tobias Ulbricht, Volker Döring, Christian Hoischen, Ronny Martin, Catarina P. Samora, Andrew D. McAinsh, Christopher W. Carroll, Aaron F. Straight, Patrick Meraldi, Stephan Diekmann
J Cell Sci. 2011 Nov 15; 124(22): 3871–3883. doi: 10.1242/jcs.088625
PMCID:
PMC3225271
AbstractArticle
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N
Christopher W. Carroll, Mariana C.C. Silva, Kristina M. Godek, Lars E.T. Jansen, Aaron F. Straight
Nat Cell Biol. Author manuscript; available in PMC 2010 Jan 1.
Published in final edited form as: Nat Cell Biol. 2009 Jul; 11(7): 896–902. Published online 2009 Jun 21. doi: 10.1038/ncb1899
PMCID:
PMC2704923
AbstractArticlePDF–1.1M

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