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Items: 1 to 20 of 111

1.
Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non‐small‐cell lung cancer
Min Kim, Hyo‐Gyoung Kang, Shin Yup Lee, Hyung Cheol Lee, Eung Bae Lee, Yi Young Choi, Won Kee Lee, Sukki Cho, Guang Jin, Hyo‐Sung Jheon, Ji Woong Son, Myung‐Hoon Lee, Deuk Kju Jung, Seung Ick Cha, Chang Ho Kim, Young Mo Kang, Sin Kam, Tae Hoon Jung, Sanghoon Jheon, Jae Yong Park
Cancer Sci. 2010 Nov; 101(11): 2436–2442. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01699.x
PMCID:
PMC11159840
AbstractArticlePDF–209K
2.
The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer
YANG DENG, TAO-WEI KE, TE-CHENG YUEH, YU-TING CHIN, YUN-CHI WANG, YI-CHIH HUNG, MEI-CHIN MONG, YA-CHEN YANG, WEN-TZU WU, WEN-SHIN CHANG, JIAN GU, DA-TIAN BAU, CHIA-WEN TSAI
In Vivo. 2024 Jan-Feb; 38(1): 127–133. Published online 2024 Jan 3. doi: 10.21873/invivo.13419
PMCID:
PMC10756467
AbstractArticlePDF–146K
3.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
4.
Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency
Annaïse J. Jauch, Olivier Bignucolo, Sayuri Seki, Marie Ghraichy, Ottavia M. Delmonte, Valentin von Niederhäusern, Rebecca Higgins, Adhideb Ghosh, Masako Nishizawa, Mariko Tanaka, Adrian Baldrich, Julius Köppen, Julia R. Hirsiger, Robin Hupfer, Stephan Ehl, Anne Rensing-Ehl, Helmut Hopfer, Spasenija Savic Prince, Stephen R. Daley, Florian A. Marquardsen, Benedikt J. Meyer, Michael Tamm, Thomas D. Daikeler, Tamara Diesch, Thomas Kühne, Arthur Helbling, Caroline Berkemeier, Ingmar Heijnen, Alexander A. Navarini, Johannes Trück, Jean-Pierre de Villartay, Annette Oxenius, Christoph T. Berger, Christoph Hess, Luigi D. Notarangelo, Hiroyuki Yamamoto, Mike Recher
J Allergy Clin Immunol. Author manuscript; available in PMC 2024 Feb 1.
Published in final edited form as: J Allergy Clin Immunol. 2023 Aug; 152(2): 500–516. Published online 2023 Mar 31. doi: 10.1016/j.jaci.2023.03.022
PMCID:
PMC10529397
AbstractArticlePDF–2.9M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
7.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
8.
Cryo-EM of NHEJ supercomplexes provides insights into DNA repair
Amanda K. Chaplin, Steven W. Hardwick, Antonia Kefala Stavridi, Christopher J. Buehl, Noah J. Goff, Virginie Ropars, Shikang Liang, Taiana Maia De Oliveira, Dimitri Y. Chirgadze, Katheryn Meek, Jean-Baptiste Charbonnier, Tom L. Blundell
Mol Cell. Author manuscript; available in PMC 2022 Aug 19.
Published in final edited form as: Mol Cell. 2021 Aug 19; 81(16): 3400–3409.e3. Published online 2021 Aug 4. doi: 10.1016/j.molcel.2021.07.005
PMCID:
PMC9006396
AbstractArticlePDF–3.0M
9.
Human DNA ligases in replication and repair
Annahita Sallmyr, Ishtiaque Rashid, Seema Khattri Bhandari, Tasmin Naila, Alan E. Tomkinson
DNA Repair (Amst) Author manuscript; available in PMC 2022 Jan 4.
Published in final edited form as: DNA Repair (Amst). 2020 Sep; 93: 102908. doi: 10.1016/j.dnarep.2020.102908
PMCID:
PMC8727047
AbstractArticlePDF–1.5M
10.
USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing
Jae Jin Kim, Seo Yun Lee, Yiseul Hwang, Soyeon Kim, Jee Min Chung, Sangwook Park, Junghyun Yoon, Hansol Yun, Jae-Hoon Ji, Sunyoung Chae, Hyeseong Cho, Chan Gil Kim, Ted M Dawson, Hongtae Kim, Valina L Dawson, Ho Chul Kang
Nucleic Acids Res. 2021 Nov 8; 49(19): 11083–11102. Published online 2021 Oct 6. doi: 10.1093/nar/gkab892
PMCID:
PMC8565343
AbstractArticlePDF–11M
11.
Characterization of a Cohort of Patients With LIG4 Deficiency Reveals the Founder Effect of p.R278L, Unique to the Chinese Population
Xianze Luo, Qing Liu, Jinqiu Jiang, Wenjing Tang, Yuan Ding, Lina Zhou, Jie Yu, Xuemei Tang, Yunfei An, Xiaodong Zhao
Front Immunol. 2021; 12: 695993. Published online 2021 Sep 24. doi: 10.3389/fimmu.2021.695993
PMCID:
PMC8498043
AbstractArticlePDF–1.9M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors
Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier
Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118
PMCID:
PMC8017720
AbstractArticlePDF–1.9M
14.
NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV
Bailin Zhao, Tasmin Naila, Michael R Lieber, Alan E Tomkinson
Nucleic Acids Res. 2020 Dec 16; 48(22): 12746–12750. Published online 2020 Dec 2. doi: 10.1093/nar/gkaa1118
PMCID:
PMC7736778
AbstractArticlePDF–682K
15.
Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol
Rutger David Luteijn, Ingo Drexler, Geoffrey L. Smith, Robert Jan Lebbink, Emmanuel J. H. J. Wiertz
J Gen Virol. Author manuscript; available in PMC 2023 Jul 27.
Published in final edited form as: J Gen Virol. 2018 Jun 1; 99(6): 790–804. Published online 2018 Apr 20. doi: 10.1099/jgv.0.001034
PMCID:
PMC7614823
AbstractArticlePDF–1.7M
16.
Inhibition of non-homologous end joining of gamma ray-induced DNA double-strand breaks by cAMP signaling in lung cancer cells
Sung-Eun Noh, Yong-Sung Juhnn
Sci Rep. 2020; 10: 14455. Published online 2020 Sep 2. doi: 10.1038/s41598-020-71522-9
PMCID:
PMC7468279
AbstractArticlePDF–5.1M
17.
Ligase IV syndrome can present with microcephaly and radial ray anomalies similar to Fanconi anaemia plus fatal kidney malformations
Rajesh Madhu, Glenda M. Beaman, Kate E. Chandler, James O'Sullivan, Jill E. Urquhart, Naz Khan, Elizabeth Martindale, Tracy A. Briggs, Jill Clayton-Smith, Jenny Higgs, Gauri Batra, Bronwyn Kerr, Adrian S. Woolf, William G. Newman
Eur J Med Genet. 2020 Sep; 63(9): 103974. doi: 10.1016/j.ejmg.2020.103974
PMCID:
PMC7445424
AbstractArticle
18.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
19.
Altered DNA ligase activity in human disease
Alan E Tomkinson, Tasmin Naila, Seema Khattri Bhandari
Mutagenesis. 2020 Feb; 35(1): 51–60. Published online 2019 Oct 20. doi: 10.1093/mutage/gez026
PMCID:
PMC7317150
AbstractArticlePDF–1.8M
20.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M

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