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Items: 1 to 20 of 27

1.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
De novo and inherited loss-of-function variants of ATP2B2 are associated with rapidly progressive hearing impairment
Jeroen J. Smits, Jaap Oostrik, Andy J. Beynon, Sarina G. Kant, Pia A. M. de Koning Gans, Liselotte J. C. Rotteveel, Jolien S. Klein Wassink-Ruiter, Rolien H. Free, Saskia M. Maas, Jiddeke van de Kamp, Paul Merkus, DOOFNL Consortium, Wouter Koole, Ilse Feenstra, Ronald J. C. Admiraal, Cornelis P. Lanting, Margit Schraders, Helger G. Yntema, Ronald J. E. Pennings, Hannie Kremer
Hum Genet. 2019; 138(1): 61–72. Published online 2018 Dec 8. doi: 10.1007/s00439-018-1965-1
PMCID:
PMC6514080
AbstractArticlePDF–1.2M
4.
Proteome‐wide analysis of phospho‐regulated PDZ domain interactions
Gustav N Sundell, Roland Arnold, Muhammad Ali, Piangfan Naksukpaiboon, Julien Orts, Peter Güntert, Celestine N Chi, Ylva Ivarsson
Mol Syst Biol. 2018 Aug; 14(8): e8129. Published online 2018 Aug 20. doi: 10.15252/msb.20178129
PMCID:
PMC6100724
AbstractArticlePDF–2.4M
5.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
6.
The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2
Jaekwang Jeong, Joshua N. VanHouten, Wonnam Kim, Pamela Dann, Catherine Sullivan, Jungmin Choi, W. Bruce Sneddon, Peter A. Friedman, John J. Wysolmerski
J Biol Chem. 2017 Apr 21; 292(16): 6555–6568. Published online 2017 Feb 24. doi: 10.1074/jbc.M116.770883
PMCID:
PMC5399107
AbstractArticlePDF–5.8M
7.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
8.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Karsten Boldt, Jeroen van Reeuwijk, Qianhao Lu, Konstantinos Koutroumpas, Thanh-Minh T. Nguyen, Yves Texier, Sylvia E. C. van Beersum, Nicola Horn, Jason R. Willer, Dorus A. Mans, Gerard Dougherty, Ideke J. C. Lamers, Karlien L. M. Coene, Heleen H. Arts, Matthew J. Betts, Tina Beyer, Emine Bolat, Christian Johannes Gloeckner, Khatera Haidari, Lisette Hetterschijt, Daniela Iaconis, Dagan Jenkins, Franziska Klose, Barbara Knapp, Brooke Latour, Stef J. F. Letteboer, Carlo L. Marcelis, Dragana Mitic, Manuela Morleo, Machteld M. Oud, Moniek Riemersma, Susan Rix, Paulien A. Terhal, Grischa Toedt, Teunis J. P. van Dam, Erik de Vrieze, Yasmin Wissinger, Ka Man Wu, Gordana Apic, Philip L. Beales, Oliver E. Blacque, Toby J. Gibson, Martijn A. Huynen, Nicholas Katsanis, Hannie Kremer, Heymut Omran, Erwin van Wijk, Uwe Wolfrum, François Kepes, Erica E. Davis, Brunella Franco, Rachel H. Giles, Marius Ueffing, Robert B. Russell, Ronald Roepman, UK10K Rare Diseases Group
Nat Commun. 2016; 7: 11491. Published online 2016 May 13. doi: 10.1038/ncomms11491
PMCID:
PMC4869170
AbstractArticlePDF–2.0M
9.
The calcium pump plasma membrane Ca2+-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin
Amelia A. Peters, Michael J. G. Milevskiy, Wei C. Lee, Merril C. Curry, Chanel E. Smart, Jodi M. Saunus, Lynne Reid, Leonard da Silva, Daneth L. Marcial, Eloise Dray, Melissa A. Brown, Sunil R. Lakhani, Sarah J. Roberts-Thomson, Gregory R. Monteith
Sci Rep. 2016; 6: 25505. Published online 2016 May 5. doi: 10.1038/srep25505
PMCID:
PMC4857793
AbstractArticlePDF–2.0M
10.
PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer
Jaekwang Jeong, Joshua N. VanHouten, Pamela Dann, Wonnam Kim, Catherine Sullivan, Herbert Yu, Lance Liotta, Virginia Espina, David F. Stern, Peter A. Friedman, John J. Wysolmerski
Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3): E282–E290. Published online 2016 Jan 4. doi: 10.1073/pnas.1516138113
PMCID:
PMC4725473
AbstractArticlePDF–2.5M
11.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
12.
Systematic VCP-UBXD Adaptor Network Proteomics Identifies a Role for UBXN10 in Regulating Ciliogenesis
Malavika Raman, Mikhail Sergeev, Maija Garnaas, John R. Lydeard, Edward L. Huttlin, Wolfram Goessling, Jagesh V. Shah, J. Wade Harper
Nat Cell Biol. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: Nat Cell Biol. 2015 Oct; 17(10): 1356–1369. Published online 2015 Sep 21. doi: 10.1038/ncb3238
Correction in:
Nat Cell Biol. 2016 Mar; 18(3): 347.
PMCID:
PMC4610257
AbstractArticlePDF–4.5M
13.
RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling
Kendra S. Carmon, Xing Gong, Jing Yi, Anthony Thomas, Qingyun Liu
Proc Natl Acad Sci U S A. 2014 Apr 1; 111(13): E1221–E1229. Published online 2014 Mar 17. doi: 10.1073/pnas.1323106111
PMCID:
PMC3977305
AbstractArticlePDF–1.7M
14.
The Evidence for Association of ATP2B2 Polymorphisms with Autism in Chinese Han Population
Wen Yang, Jing Liu, Fanfan Zheng, Meixiang Jia, Linnan Zhao, Tianlan Lu, Yanyan Ruan, Jishui Zhang, Weihua Yue, Dai Zhang, Lifang Wang
PLoS One. 2013; 8(4): e61021. Published online 2013 Apr 19. doi: 10.1371/journal.pone.0061021
PMCID:
PMC3631200
AbstractArticlePDF–185K
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Apical localization of PMCA2w/b is enhanced in terminally polarized MDCK cells
Géza Antalffy, Ariel J. Caride, Katalin Pászty, Luca Hegedus, Rita Padanyi, Emanuel E. Strehler, Ágnes Enyedi
Biochem Biophys Res Commun. Author manuscript; available in PMC 2012 Jul 1.
Published in final edited form as: Biochem Biophys Res Commun. 2011 Jul 1; 410(2): 322–327. Published online 2011 Jun 6. doi: 10.1016/j.bbrc.2011.05.147
PMCID:
PMC3139432
AbstractArticlePDF–1.0M
17.
Apical Scaffolding Protein NHERF2 Modulates the Localization of Alternatively Spliced Plasma Membrane Ca2+ Pump 2B Variants in Polarized Epithelial Cells
Rita Padányi, Yuning Xiong, Géza Antalffy, Krisztina Lór, Katalin Pászty, Emanuel E. Strehler, Ágnes Enyedi
J Biol Chem. 2010 Oct 8; 285(41): 31704–31712. Published online 2010 Jul 27. doi: 10.1074/jbc.M110.164137
PMCID:
PMC2951242
AbstractArticlePDF–2.5M
18.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
19.
Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells
MaryLouisa Holton, Tamer M.A. Mohamed, Delvac Oceandy, Weiguang Wang, Santiago Lamas, Michael Emerson, Ludwig Neyses, Angel L. Armesilla
Cardiovasc Res. 2010 Aug 1; 87(3): 440–448. Published online 2010 Mar 7. doi: 10.1093/cvr/cvq077
PMCID:
PMC2904661
AbstractArticlePDF–395K
20.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M

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