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Select item 108972121.

Structural insight into the allosteric inhibition of human sodium-calcium exchanger NCX1 by XIP and SEA0400

Yanli Dong, Zhuoya Yu, Yue Li, Bo Huang, Qinru Bai, Yiwei Gao, Qihao Chen, Na Li, Lingli He, Yan Zhao

EMBO J. 2024 Jan; 43(1): 14–31. Published online 2023 Dec 15. doi: 10.1038/s44318-023-00013-0

PMCID:: PMC10897212

Abstract Article PDF–5.0M

Select item 107016012.

LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition

Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon‐Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan‐Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub

EMBO Mol Med. 2023 Dec; 15(12): e17719. Published online 2023 Nov 15. doi: 10.15252/emmm.202317719

Correction in:: EMBO Mol Med. 2024 Sep; 16(9): 2262–2267.

PMCID:: PMC10701601

Abstract Article PDF–3.7M

Select item 105509453.

Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1

Jing Xue, Weizhong Zeng, Yan Han, Scott John, Michela Ottolia, Youxing Jiang

Nat Commun. 2023; 14: 6181. Published online 2023 Oct 4. doi: 10.1038/s41467-023-41885-4

PMCID:: PMC10550945

Abstract Article PDF–2.6M

Select item 104607174.

NCX1 disturbs calcium homeostasis and promotes RANKL-induced osteoclast differentiation by regulating JNK/c-Fos/NFATc1 signaling pathway in multiple myeloma

Tingting Li, Dongbiao Qiu, Qingjiao Chen, Apeng Yang, Junmin Chen, Zhiyong Zeng

Clin Exp Med. 2023; 23(5): 1581–1596. Published online 2022 Oct 17. doi: 10.1007/s10238-022-00905-1

PMCID:: PMC10460717

Abstract Article PDF–4.2M

Select item 103747865.

Association of polymorphisms of calcium reabsorption genes SLC12A1, KCNJ1 and SLC8A1 with colorectal adenoma

Xiaolian Lai, Shuoyan Lu, Jia Jiang, Hanqun Zhang, Qinglin Yang, Yuncong Liu, Libo Li, Sanming Li, Si Dai, Yanping Chen, Yan Chen, Jun Liu, Yong Li

J Cancer Res Clin Oncol. 2023; 149(11): 8335–8344. Published online 2023 Apr 19. doi: 10.1007/s00432-023-04773-4

PMCID:: PMC10374786

Abstract Article PDF–639K

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 94180007.

NCX1 coupled with TRPC1 to promote gastric cancer via Ca²⁺/AKT/β-catenin pathway

Hanxing Wan, Nannan Gao, Wei Lu, Cheng Lu, Jun Chen, Yimin Wang, Hui Dong

Oncogene. 2022; 41(35): 4169–4182. Published online 2022 Jul 26. doi: 10.1038/s41388-022-02412-9

PMCID:: PMC9418000

Abstract Article PDF–9.9M

Select item 87266078.

Circular RNA circSLC8A1 inhibits the proliferation and invasion of non-small cell lung cancer cells through targeting the miR-106b-5p /FOXJ3 axis

Wenmu Yong, Shujiao Deng, Yunfang Tan, Sen Li

Cell Cycle. 2021; 20(24): 2597–2606. Published online 2021 Nov 1. doi: 10.1080/15384101.2021.1995968

PMCID:: PMC8726607

Abstract Article PDF–1.6M

Select item 82044729.

The downregulation of NCXs is positively correlated with the prognosis of stage II–IV colon cancer

Zhixiu Xia, Changliang Wang, Hong Zhang

World J Surg Oncol. 2021; 19: 177. Published online 2021 Jun 14. doi: 10.1186/s12957-021-02284-5

PMCID:: PMC8204472

Abstract Article PDF–8.6M

Select item 808783210.

The hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke

Valeria Valsecchi, Giusy Laudati, Ornella Cuomo, Rossana Sirabella, Annalisa Del Prete, Lucio Annunziato, Giuseppe Pignataro

Cell Death Dis. 2021 May; 12(5): 423. Published online 2021 Apr 30. doi: 10.1038/s41419-021-03705-9

Correction in:: Cell Death Dis. 2023 Jul; 14(7): 484.

PMCID:: PMC8087832

Abstract Article PDF–1.0M

Select item 756349911.

Gateways for Glutamate Neuroprotection in Parkinson’s Disease (PD): Essential Role of EAAT3 and NCX1 Revealed in an In Vitro Model of PD

Silvia Piccirillo, Simona Magi, Alessandra Preziuso, Pasqualina Castaldo, Salvatore Amoroso, Vincenzo Lariccia

Cells. 2020 Sep; 9(9): 2037. Published online 2020 Sep 6. doi: 10.3390/cells9092037

PMCID:: PMC7563499

Abstract Article PDF–2.7M

Select item 607772212.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 602386613.

Glutamate as a potential “survival factor” in an in vitro model of neuronal hypoxia/reoxygenation injury: leading role of the Na⁺/Ca²⁺ exchanger

Silvia Piccirillo, Pasqualina Castaldo, Maria Loredana Macrì, Salvatore Amoroso, Simona Magi

Cell Death Dis. 2018 Jul; 9(7): 731. Published online 2018 Jun 28. doi: 10.1038/s41419-018-0784-6

PMCID:: PMC6023866

Abstract Article PDF–1.5M

Select item 555741814.

Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women

Rita Papp, Glenna C. L. Bett, Agnieszka Lis, Randall L. Rasmusson, István Baczkó, András Varró, Guy Salama

Biol Sex Differ. 2017; 8: 26. Published online 2017 Aug 14. doi: 10.1186/s13293-017-0148-4

PMCID:: PMC5557418

Abstract Article PDF–1.2M

Select item 541939815.

Splice Variant-Dependent Regulation of β-Cell Sodium-Calcium Exchange by Acyl-Coenzyme As

Kevin S. C. Hamming, Michael J. Riedel, Daniel Soliman, Laura C. Matemisz, Nicola J. Webster, Gavin J. Searle, Patrick E. MacDonald, Peter E. Light

Mol Endocrinol. October 1, 2008; 22(10): 2293–2306. doi: 10.1210/me.2008-0053

PMCID:: PMC5419398

Abstract Article

Select item 532540616.

Essential role of Na⁺/Ca2⁺ exchanger 1 in smoking-induced growth and migration of esophageal squamous cell carcinoma

Jiexia Wen, Yan Pang, Tao Zhou, Ximing Qi, Min Zhao, Bin Xuan, Xiangcai Meng, Yunsheng Guo, Qingbin Liu, Huagang Liang, Yang Li, Hui Dong, Yimin Wang

Oncotarget. 2016 Sep 27; 7(39): 63816–63828. Published online 2016 Aug 30. doi: 10.18632/oncotarget.11695

PMCID:: PMC5325406

Abstract Article PDF–6.5M

Select item 496497717.

Development of a high-affinity peptide that prevents phospholemman (PLM) inhibition of the sodium/calcium exchanger 1 (NCX1)

Pimthanya Wanichawan, Kjetil Hodne, Tandekile Lubelwana Hafver, Marianne Lunde, Marita Martinsen, William Edward Louch, Ole Mathias Sejersted, Cathrine Rein Carlson

Biochem J. 2016 Aug 1; 473(15): 2413–2423. Prepublished online 2016 May 31. Published online 2016 Jul 28. doi: 10.1042/BCJ20160465

PMCID:: PMC4964977

Abstract Article PDF–1.3M

Select item 496098618.

S-palmitoylation and the regulation of NCX1

William Fuller, Louise Reilly, Donald W Hilgemann

Channels (Austin) 2016 Mar-Apr; 10(2): 75–77. Published online 2015 Sep 29. doi: 10.1080/19336950.2015.1099329

PMCID:: PMC4960986

Article PDF–337K

Select item 481650219.

Endothelial Cells Can Regulate Smooth Muscle Cells in Contractile Phenotype through the miR-206/ARF6&NCX1/Exosome Axis

Xiao Lin, Yu He, Xue Hou, Zhenming Zhang, Rui Wang, Qiong Wu

PLoS One. 2016; 11(3): e0152959. Published online 2016 Mar 31. doi: 10.1371/journal.pone.0152959

PMCID:: PMC4816502

Abstract Article PDF–4.1M

Select item 466399320.

Enhanced Sarcoplasmic Reticulum Ca²⁺-leak and Increased Na⁺-Ca²⁺-Exchanger Function Underlie Delayed Afterdepolarizations in Patients with Chronic Atrial Fibrillation

Niels Voigt, Na Li, Qiongling Wang, Wei Wang, Andrew W. Trafford, Issam Abu-Taha, Qiang Sun, Thomas Wieland, Ursula Ravens, Stanley Nattel, Xander HT. Wehrens, Dobromir Dobrev

Circulation. Author manuscript; available in PMC 2015 Nov 30.

Published in final edited form as: Circulation. 2012 May 1; 125(17): 2059–2070. Published online 2012 Mar 28. doi: 10.1161/CIRCULATIONAHA.111.067306

PMCID:: PMC4663993

Abstract Article PDF–1.0M

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PMC Links for GEO Profiles (Select 121739856) (57)
PMC
PMC Links for Gene (Select 130733) (8)
PMC
transmembrane protein 178A isoform X5 [Homo sapiens]
transmembrane protein 178A isoform X5 [Homo sapiens]
gi|2462570223|ref|XP_054196561.1|

Protein
PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript varian...
PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X3, mRNA
gi|530367240|ref|XM_005264145.1|

Nucleotide
transmembrane protein 178A isoform X1 [Homo sapiens]
transmembrane protein 178A isoform X1 [Homo sapiens]
gi|2462570207|ref|XP_054196553.1|

Protein

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