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Select item 110888891.

Ruiyun Deng, Lili Zhu, Jun Jiang, Jing Chen, Hua Li

Biomol Biomed. 2024 Jun 1; 24(3): 647–658. Published online 2024 Jun 1. doi: 10.17305/bb.2023.9931

PMCID:: PMC11088889

Abstract Article PDF–3.8M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 96678233.

Copper coordination states affect the flexibility of copper Metallochaperone Atox1: Insights from molecular dynamics simulations

Renana Schwartz, Sharon Ruthstein, Dan Thomas Major

Protein Sci. 2022 Dec; 31(12): e4464. doi: 10.1002/pro.4464

PMCID:: PMC9667823

Abstract Article PDF–2.0M

Select item 95992884.

Crystal Structure of the Human Copper Chaperone ATOX1 Bound to Zinc Ion

Vincenzo Mangini, Benny Danilo Belviso, Maria Incoronata Nardella, Giovanni Natile, Fabio Arnesano, Rocco Caliandro

Biomolecules. 2022 Oct; 12(10): 1494. Published online 2022 Oct 16. doi: 10.3390/biom12101494

PMCID:: PMC9599288

Abstract Article PDF–2.0M

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 94773926.

Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro

Xiaolu Zhang, Gulshan R. Walke, Istvan Horvath, Ranjeet Kumar, Stéphanie Blockhuys, Stellan Holgersson, Paul H. Walton, Pernilla Wittung-Stafshede

Proc Natl Acad Sci U S A. 2022 Sep 13; 119(37): e2206905119. Published online 2022 Sep 6. doi: 10.1073/pnas.2206905119

PMCID:: PMC9477392

Abstract Article PDF–1.2M

Select item 92792857.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 74327818.

An EPR Study on the Interaction between the Cu(I) Metal Binding Domains of ATP7B and the Atox1 Metallochaperone

Michael Zaccak, Zena Qasem, Lada Gevorkyan-Airapetov, Sharon Ruthstein

Int J Mol Sci. 2020 Aug; 21(15): 5536. Published online 2020 Aug 2. doi: 10.3390/ijms21155536

PMCID:: PMC7432781

Abstract Article PDF–2.4M

Select item 73923349.

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells

Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull

PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606

PMCID:: PMC7392334

Abstract Article PDF–2.7M

Select item 729480610.

Cu(I) Controls Conformational States in Human Atox1 Metallochaperone: An EPR and Multiscale Simulation Study

Ortal Perkal, Zena Qasem, Meital Turgeman, Renana Schwartz, Lada Gevorkyan-Airapetov, Matic Pavlin, Alessandra Magistrato, Dan Thomas Major, Sharon Ruthstein

J Phys Chem B. 2020 Jun 4; 124(22): 4399–4411. Published online 2020 May 12. doi: 10.1021/acs.jpcb.0c01744

PMCID:: PMC7294806

Abstract Article PDF–5.3M

Select item 719607811.

Evaluation of copper chaperone ATOX1 as prognostic biomarker in breast cancer

Stéphanie Blockhuys, Donita C. Brady, Pernilla Wittung-Stafshede

Breast Cancer. 2020; 27(3): 505–509. Published online 2020 Jan 2. doi: 10.1007/s12282-019-01044-4

PMCID:: PMC7196078

Abstract Article PDF–662K

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 699500013.

Single-cell tracking demonstrates copper chaperone Atox1 to be required for breast cancer cell migration

Stéphanie Blockhuys, Xiaolu Zhang, Pernilla Wittung-Stafshede

Proc Natl Acad Sci U S A. 2020 Jan 28; 117(4): 2014–2019. Published online 2020 Jan 13. doi: 10.1073/pnas.1910722117

PMCID:: PMC6995000

Abstract Article PDF–1.1M

Select item 697416214.

Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer

Arundhati Jana, Archita Das, Nancy L. Krett, Grace Guzman, Alexandra Thomas, Georgina Mancinelli, Jessica Bauer, Masuko Ushio-Fukai, Tohru Fukai, Barbara Jung

PLoS One. 2020; 15(1): e0227916. Published online 2020 Jan 21. doi: 10.1371/journal.pone.0227916

PMCID:: PMC6974162

Abstract Article PDF–4.2M

Select item 695738615.

Novel interaction of antioxidant-1 with TRAF4: role in inflammatory responses in endothelial cells

Archita Das, Varadarajan Sudhahar, Masuko Ushio-Fukai, Tohru Fukai

Am J Physiol Cell Physiol. 2019 Dec 1; 317(6): C1161–C1171. Published online 2019 Sep 25. doi: 10.1152/ajpcell.00264.2019

PMCID:: PMC6957386

Abstract Article

Select item 677813716.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 669399017.

Copper chaperone ATOX1 is required for MAPK signaling and growth in BRAF mutation-positive melanoma

Ye-Jin Kim, Gavin J. Bond, Tiffany Tsang, Jessica M. Posimo, Luca Busino, Donita C. Brady

Metallomics. Author manuscript; available in PMC 2019 Aug 14.

Published in final edited form as: Metallomics. 2019 Aug 1; 11(8): 1430–1440. Published online 2019 Jul 18. doi: 10.1039/c9mt00042a

PMCID:: PMC6693990

Abstract Article PDF–1.6M

Select item 642409818.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

Select item 567858119.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 567204020.

The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics

Corey H. Yu, Nan Yang, Jameson Bothe, Marco Tonelli, Sergiy Nokhrin, Natalia V. Dolgova, Lelita Braiterman, Svetlana Lutsenko, Oleg Y. Dmitriev

J Biol Chem. 2017 Nov 3; 292(44): 18169–18177. Published online 2017 Sep 12. doi: 10.1074/jbc.M117.811752

PMCID:: PMC5672040

Abstract Article PDF–1.5M

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