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Select item 111786081.

Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps

Seyedeh Nasim Mirbahari, Nayeralsadat Fatemi, Sanaz Savabkar, Vahid Chaleshi, Neda Zali, Mohammad Yaghoob Taleghani, Ebrahim Mirzaei, Leili Rejali, Pardis Ketabi Moghadam, Ehsan Nazemalhosseini Mojarad

Mol Biol Rep. 2024; 51(1): 764. Published online 2024 Jun 14. doi: 10.1007/s11033-024-09683-3

PMCID:: PMC11178608

Abstract Article PDF–2.9M

Select item 110681992.

The associations of IGF2, IGF2R and IGF2BP2 gene polymorphisms with gestational diabetes mellitus: A case-control study

Wei Li, Lu She, Muyu Zhang, Mei Yang, Wenpei Zheng, Hua He, Ping Wang, Qiong Dai, Zhengtao Gong

PLoS One. 2024; 19(5): e0298063. Published online 2024 May 3. doi: 10.1371/journal.pone.0298063

PMCID:: PMC11068199

Abstract Article PDF–614K

Select item 110124063.

IGF-1 and IGF-2 as Molecules Linked to Causes and Consequences of Obesity from Fetal Life to Adulthood: A Systematic Review

Justyna Szydlowska-Gladysz, Adrianna Edyta Gorecka, Julia Stepien, Izabela Rysz, Iwona Ben-Skowronek

Int J Mol Sci. 2024 Apr; 25(7): 3966. Published online 2024 Apr 2. doi: 10.3390/ijms25073966

PMCID:: PMC11012406

Abstract Article PDF–2.5M

Select item 109608144.

Activation of the insulin receptor by insulin-like growth factor 2

Weidong An, Catherine Hall, Jie Li, Albert Hung, Jiayi Wu, Junhee Park, Liwei Wang, Xiao-chen Bai, Eunhee Choi

Nat Commun. 2024; 15: 2609. Published online 2024 Mar 23. doi: 10.1038/s41467-024-46990-6

PMCID:: PMC10960814

Abstract Article PDF–5.6M

Select item 103788695.

The Role of SOX9 in IGF-II-Mediated Pulmonary Fibrosis

Kristy M. Waldrep, Jessalyn I. Rodgers, Sara M. Garrett, Bethany J. Wolf, Carol A. Feghali-Bostwick

Int J Mol Sci. 2023 Jul; 24(14): 11234. Published online 2023 Jul 8. doi: 10.3390/ijms241411234

PMCID:: PMC10378869

Abstract Article PDF–2.8M

Select item 101921306.

IGF2 in memory, neurodevelopmental disorders, and neurodegenerative diseases

Cristina M. Alberini

Trends Neurosci. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Trends Neurosci. 2023 Jun; 46(6): 488–502. Published online 2023 Apr 6. doi: 10.1016/j.tins.2023.03.007

PMCID:: PMC10192130

Abstract Article PDF–1.1M

Select item 101737267.

Insulin‐like growth factor‐2 is a promising candidate for the treatment and prevention of Alzheimer's disease

G. S. Fitzgerald, T. G. Chuchta, E. C. McNay

CNS Neurosci Ther. 2023 Jun; 29(6): 1449–1469. Published online 2023 Mar 27. doi: 10.1111/cns.14160

PMCID:: PMC10173726

Abstract Article PDF–1.6M

Select item 100733008.

Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma

Jordi Abril-Fornaguera, Laura Torrens, Carmen Andreu-Oller, Juan Carrillo-Reixach, Alex Rialdi, Ugne Balaseviciute, Roser Pinyol, Carla Montironi, Philipp K. Haber, Álvaro Del Río-Álvarez, Montserrat Domingo-Sàbat, Laura Royo, Nicholas K. Akers, Catherine E. Willoughby, Judit Peix, Miguel Torres-Martin, Marc Puigvehi, Stefano Cairo, Margaret Childs, Rudolf Maibach, Rita Alaggio, Piotr Czauderna, Bruce Morland, Bojan Losic, Vincenzo Mazzaferro, Ernesto Guccione, Daniela Sia, Carolina Armengol, Josep M. Llovet

Mol Cancer Ther. Author manuscript; available in PMC 2023 Oct 3.

Published in final edited form as: Mol Cancer Ther. 2023 Apr 3; 22(4): 485–498. doi: 10.1158/1535-7163.MCT-22-0335

PMCID:: PMC10073300

Abstract Article PDF–1.8M

Select item 100729069.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 1004897310.

Glycosylation Analysis of Urinary Peptidome Highlights IGF2 Glycopeptides in Association with CKD

Sonnal Lohia, Agnieszka Latosinska, Jerome Zoidakis, Manousos Makridakis, Harald Mischak, Griet Glorieux, Antonia Vlahou, Vera Jankowski

Int J Mol Sci. 2023 Mar; 24(6): 5402. Published online 2023 Mar 11. doi: 10.3390/ijms24065402

PMCID:: PMC10048973

Abstract Article PDF–3.0M

Select item 1000235111.

Synergic Action of Insulin-like Growth Factor-2 and miRNA-483 in Pterygium Pathogenesis

Cristina Maxia, Michela Isola, Eleonora Grecu, Alberto Cuccu, Alessandra Scano, Germano Orrù, Nick Di Girolamo, Andrea Diana, Daniela Murtas

Int J Mol Sci. 2023 Mar; 24(5): 4329. Published online 2023 Feb 22. doi: 10.3390/ijms24054329

PMCID:: PMC10002351

Abstract Article PDF–2.2M

Select item 989922612.

Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1–42 in Alzheimer’s disease

Emre Fertan, William H. Gendron, Aimée A. Wong, Gabrielle M. Hanson, Richard E. Brown, Ian C. G. Weaver

Sci Rep. 2023; 13: 2043. Published online 2023 Feb 4. doi: 10.1038/s41598-023-29248-x

PMCID:: PMC9899226

Abstract Article PDF–2.3M

Select item 974492913.

Sperm-carried IGF2 downregulated the expression of mitogens produced by Sertoli cells: A paracrine mechanism for regulating spermatogenesis?

Rossella Cannarella, Francesca Mancuso, Iva Arato, Cinzia Lilli, Catia Bellucci, Marco Gargaro, Roberto Curto, Maria C. Aglietti, Sandro La Vignera, Rosita A. Condorelli, Giovani Luca, Aldo E. Calogero

Front Endocrinol (Lausanne) 2022; 13: 1010796. Published online 2022 Nov 29. doi: 10.3389/fendo.2022.1010796

PMCID:: PMC9744929

Abstract Article PDF–10M

Select item 968753114.

Insulin-like Growth Factor-2 (IGF-2) in Fibrosis

Yuhan Zhu, Lin Chen, Binyu Song, Zhiwei Cui, Guo Chen, Zhou Yu, Baoqiang Song

Biomolecules. 2022 Nov; 12(11): 1557. Published online 2022 Oct 25. doi: 10.3390/biom12111557

PMCID:: PMC9687531

Abstract Article PDF–860K

Select item 952942915.

Altered expression of the IGF2-H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma

Patrick Scicluna, Stefano Caramuta, Hanna Kjellin, Cheng Xu, Robin Fröbom, Monira Akhtar, Jiwei Gao, Hao Shi, Magnus Kjellman, Malin Almgren, Anders Höög, Jan Zedenius, Tomas J. Ekström, Robert Bränström, Weng-Onn Lui, Catharina Larsson

Int J Oncol. 2022 Nov; 61(5): 140. Published online 2022 Sep 27. doi: 10.3892/ijo.2022.5430

PMCID:: PMC9529429

Abstract Article PDF–3.6M

Select item 938157416.

FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma

Junjun Li, Yongchang Zhang, Li Wang, Min Li, Jianbo Yang, Pan Chen, Jie Zhu, Xiayu Li, Zhaoyang Zeng, Guiyuan Li, Wei Xiong, James B. McCarthy, Bo Xiang, Mei Yi

Cell Death Dis. 2022 Aug; 13(8): 711. Published online 2022 Aug 16. doi: 10.1038/s41419-022-05150-8

PMCID:: PMC9381574

Abstract Article PDF–12M

Select item 931354517.

Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma

Deepak Kumar, Manasi Das, Alexis Oberg, Debashis Sahoo, Panyisha Wu, Consuelo Sauceda, Lily Jih, Lesley G. Ellies, Magda T. Langiewicz, Supriya Sen, Nicholas J. G. Webster

Adv Sci (Weinh) 2022 Jul; 9(21): 2105120. Published online 2022 May 26. doi: 10.1002/advs.202105120

PMCID:: PMC9313545

Abstract Article PDF–7.7M

Select item 917141118.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 916679119.

Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells

Liang-Liang Fan, Ran Du, Ji-Shi Liu, Jie-Yuan Jin, Chen-Yu Wang, Yi Dong, Wan-Xia He, Ri-Qiang Yan, Rong Xiang

Exp Mol Med. 2022 May; 54(5): 653–661. Published online 2022 May 20. doi: 10.1038/s12276-022-00763-7

PMCID:: PMC9166791

Abstract Article PDF–4.6M

Select item 877156020.

Overexpression of BACH1 mediated by IGF2 facilitates hepatocellular carcinoma growth and metastasis via IGF1R and PTK2

Meng Xie, Mengyu Sun, Xiaoyu Ji, Dongxiao Li, Xiaoping Chen, Bixiang Zhang, Wenjie Huang, Tongyue Zhang, Yijun Wang, Dean Tian, Limin Xia

Theranostics. 2022; 12(3): 1097–1116. Published online 2022 Jan 1. doi: 10.7150/thno.65775

PMCID:: PMC8771560

Abstract Article PDF–5.6M

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