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Items: 1 to 20 of 51

1.
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8
PMCID:
PMC10499821
AbstractArticlePDF–2.6M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
A proteome-scale map of the SARS-CoV-2–human contactome
Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun
Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z
PMCID:
PMC9849141
AbstractArticlePDF–7.1M
4.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
5.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
6.
Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action
Jeremiah D. Paskus, Chen Tian, Erin Fingleton, Christine Shen, Xiaobing Chen, Yan Li, Samuel A. Myers, John D. Badger, II, Michael A. Bemben, Bruce E. Herring, Katherine W. Roche
Cell Rep. Author manuscript; available in PMC 2022 Apr 15.
Published in final edited form as: Cell Rep. 2019 Dec 3; 29(10): 2944–2952.e5. doi: 10.1016/j.celrep.2019.10.115
PMCID:
PMC9012321
AbstractArticlePDF–1.8M
7.
Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma
Elena A Afanasyeva, Moritz Gartlgruber, Tatsiana Ryl, Bieke Decaesteker, Geertrui Denecker, Gregor Mönke, Umut H Toprak, Andres Florez, Alica Torkov, Daniel Dreidax, Carl Herrmann, Konstantin Okonechnikov, Sara Ek, Ashwini Kumar Sharma, Vitaliya Sagulenko, Frank Speleman, Kai-Oliver Henrich, Frank Westermann
Life Sci Alliance. 2021 May; 4(5): e201900332. Published online 2021 Mar 3. doi: 10.26508/lsa.201900332
PMCID:
PMC8017594
AbstractArticlePDF–8.3M
8.
KALRN mutations promote antitumor immunity and immunotherapy response in cancer
Mengyuan Li, Yuxiang Ma, You Zhong, Qian Liu, Canping Chen, Lei Qiang, Xiaosheng Wang
J Immunother Cancer. 2020; 8(2): e000293. Published online 2020 Oct 9. doi: 10.1136/jitc-2019-000293
PMCID:
PMC7549479
AbstractArticlePDF–5.9M
9.
Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex
Marissa M. Minor, F. Blaine Hollinger, Adrienne L. McNees, Sung Yun Jung, Antrix Jain, Joseph M. Hyser, Karl-Dimiter Bissig, Betty L. Slagle
Cells. 2020 Apr; 9(4): 834. Published online 2020 Mar 30. doi: 10.3390/cells9040834
PMCID:
PMC7226812
AbstractArticlePDF–2.3M
10.
Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis
Anthony W. Harrington, Ju Young Kim, Sung Ok Yoon
J Neurosci. 2002 Jan 1; 22(1): 156–166. doi: 10.1523/JNEUROSCI.22-01-00156.2002
PMCID:
PMC6757583
AbstractArticlePDF–582K
11.
Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin
Younsang Oh, Leslie W. -M. Fung
Cell Mol Biol Lett. 2007 Dec; 12(4): 604–620. Published online 2007 Jul 3. doi: 10.2478/s11658-007-0028-8
PMCID:
PMC6275721
SummaryPDF–463K
12.
The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival
Hollis McClory, Xiaolong Wang, Ellen Sapp, Leah W. Gatune, Maria Iuliano, Chiu-Yi Wu, Gina Nathwani, Kimberly B. Kegel-Gleason, Marian DiFiglia, Xueyi Li
Sci Rep. 2018; 8: 8000. Published online 2018 May 22. doi: 10.1038/s41598-018-26255-1
PMCID:
PMC5964228
AbstractArticlePDF–1.9M
13.
G908R NOD2 variant in a family with sarcoidosis
Valérie Besnard, Alain Calender, Diane Bouvry, Yves Pacheco, Catherine Chapelon-Abric, Florence Jeny, Hilario Nunes, Carole Planès, Dominique Valeyre
Respir Res. 2018; 19: 44. Published online 2018 Mar 20. doi: 10.1186/s12931-018-0748-5
PMCID:
PMC5859391
AbstractArticlePDF–721K
14.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
15.
A schizophrenia-linked KALRN coding variant alters neuron morphology, protein function, and transcript stability
Theron A. Russell, Melanie J. Grubisha, Christine L. Remmers, Seok Kyu Kang, Marc P. Forrest, Katharine R. Smith, Katherine J. Kopeikina, Ruoqi Gao, Robert A. Sweet, Peter Penzes
Biol Psychiatry. Author manuscript; available in PMC 2019 Mar 15.
Published in final edited form as: Biol Psychiatry. 2018 Mar 15; 83(6): 499–508. Published online 2017 Nov 7. doi: 10.1016/j.biopsych.2017.10.024
PMCID:
PMC5809265
AbstractArticlePDF–1.7M
16.
Kalirin-7 is a Key Player in the Formation of Excitatory Synapses in Hippocampal Neurons
Xin-Ming Ma
ScientificWorldJournal. 2010; 10: 1655–1666. Published online 2010 Aug 17. doi: 10.1100/tsw.2010.148
PMCID:
PMC5763952
AbstractPDF–731K
17.
Genetic Variant of Kalirin Gene Is Associated with Ischemic Stroke in a Chinese Han Population
Hong Li, Shasha Yu, Rui Wang, Zhaoqing Sun, Xinghu Zhou, Liqiang Zheng, Zhihua Yin, Xingang Zhang, Yingxian Sun
Biomed Res Int. 2017; 2017: 6594271. Published online 2017 Jun 19. doi: 10.1155/2017/6594271
PMCID:
PMC5494542
AbstractArticlePDF–752K
18.
Kalirin and CHD7: novel endothelial dysfunction indicators in circulating extracellular vesicles from hypertensive patients with albuminuria
Fernando de la Cuesta, Montserrat Baldan-Martin, Rafael Moreno-Luna, Gloria Alvarez-Llamas, Laura Gonzalez-Calero, Laura Mourino-Alvarez, Tamara Sastre-Oliva, Juan A. López, Jesús Vázquez, Gema Ruiz-Hurtado, Julian Segura, Fernando Vivanco, Luis M. Ruilope, Maria G. Barderas
Oncotarget. 2017 Feb 28; 8(9): 15553–15562. Published online 2017 Feb 1. doi: 10.18632/oncotarget.14948
PMCID:
PMC5362505
AbstractArticlePDF–10M
19.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
20.
Exome sequencing discloses KALRN homozygous variant as likely cause of intellectual disability and short stature in a consanguineous pedigree
Periklis Makrythanasis, Michel Guipponi, Federico A. Santoni, Maha Zaki, Mahmoud Y. Issa, Muhammad Ansar, Hanan Hamamy, Stylianos E. Antonarakis
Hum Genomics. 2016; 10: 26. Published online 2016 Jul 16. doi: 10.1186/s40246-016-0082-2
PMCID:
PMC4947303
AbstractArticlePDF–1.6M

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