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Select item 111871791.

Identification of endothelial and mesenchymal FOXF1 enhancers involved in alveolar capillary dysplasia

Guolun Wang, Bingqiang Wen, Minzhe Guo, Enhong Li, Yufang Zhang, Jeffrey A. Whitsett, Tanya V. Kalin, Vladimir V. Kalinichenko

Nat Commun. 2024; 15: 5233. Published online 2024 Jun 19. doi: 10.1038/s41467-024-49477-6

PMCID:: PMC11187179

Abstract Article PDF–4.6M

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 110991273.

FOXF1 promotes tumor vessel normalization and prevents lung cancer progression through FZD4

Fenghua Bian, Chinmayee Goda, Guolun Wang, Ying-Wei Lan, Zicheng Deng, Wen Gao, Anusha Acharya, Abid A Reza, Jose Gomez-Arroyo, Nawal Merjaneh, Xiaomeng Ren, Jermaine Goveia, Peter Carmeliet, Vladimir V Kalinichenko, Tanya V Kalin

EMBO Mol Med. 2024 May; 16(5): 1063–1090. Published online 2024 Apr 8. doi: 10.1038/s44321-024-00064-8

PMCID:: PMC11099127

Abstract Article PDF–18M

Select item 96516024.

High‐level gonosomal mosaicism for a pathogenic non‐coding CNV deletion of the lung‐specific FOXF1 enhancer in an unaffected mother of an infant with ACDMPV

Esra Yıldız Bölükbaşı, Justyna A. Karolak, Przemyslaw Szafranski, Tomasz Gambin, Nicholas Willard, Steven H. Abman, Csaba Galambos, John P. Kinsella, Paweł Stankiewicz

Mol Genet Genomic Med. 2022 Nov; 10(11): e2062. Published online 2022 Sep 20. doi: 10.1002/mgg3.2062

PMCID:: PMC9651602

Abstract Article PDF–1.2M

Select item 95541845.

Variable expressivity in a four-generation ACDMPV family with a non-coding hypermorphic SNV in trans to the frameshifting FOXF1 variant

Esra Yıldız Bölükbaşı, Justyna A. Karolak, Przemyslaw Szafranski, Tomasz Gambin, Admire Matsika, Sam McManus, Hamish S. Scott, Peer Arts, Thuong Ha, Christopher P. Barnett, Jonathan Rodgers, Paweł Stankiewicz

Eur J Hum Genet. 2022 Oct; 30(10): 1182–1186. Published online 2022 Jul 28. doi: 10.1038/s41431-022-01159-x

PMCID:: PMC9554184

Abstract Article PDF–558K

Select item 93568426.

FOXF1 Was Identified as a Novel Biomarker of Infantile Hemangioma by Weighted Coexpression Network Analysis and Differential Gene Expression Analysis

Yuchao Zhang, Ping Wang

Contrast Media Mol Imaging. 2022; 2022: 8981078. Published online 2022 Jul 30. doi: 10.1155/2022/8981078

PMCID:: PMC9356842

Abstract Article PDF–2.1M

Select item 92962597.

Forkhead box F1 induces columnar phenotype and epithelial-to-mesenchymal transition in esophageal squamous cells to initiate Barrett’s like metaplasia

Alok De, Jianping Zhou, Pi Liu, Manling Huang, Sumedha Gunewardena, Sharad C. Mathur, Lane K. Christenson, Mukut Sharma, Qiuyang Zhang, Ajay Bansal

Lab Invest. Author manuscript; available in PMC 2022 Jul 19.

Published in final edited form as: Lab Invest. 2021 Jun; 101(6): 745–759. Published online 2021 Jan 25. doi: 10.1038/s41374-021-00534-4

PMCID:: PMC9296259

Abstract Article PDF–781K

Select item 90402378.

LINC00022 acts as an oncogene in colorectal cancer progression via sponging miR-375-3p to regulate FOXF1 expression

Lingling Xu, Hongmei He, Yu Shang, Xiaona Qu, Jinghua Sun

BMC Cancer. 2022; 22: 453. Published online 2022 Apr 26. doi: 10.1186/s12885-022-09566-5

PMCID:: PMC9040237

Abstract Article PDF–12M

Select item 83233029.

Genome wide DNA methylation analysis of alveolar capillary dysplasia lung tissue reveals aberrant methylation of genes involved in development including the FOXF1 locus

Evelien Slot, Ruben Boers, Joachim Boers, Wilfred F. J. van IJcken, Dick Tibboel, Joost Gribnau, Robbert Rottier, Annelies de Klein

Clin Epigenetics. 2021; 13: 148. Published online 2021 Jul 29. doi: 10.1186/s13148-021-01134-1

PMCID:: PMC8323302

Abstract Article PDF–1.6M

Select item 831402910.

Perturbation of semaphorin and VEGF signaling in ACDMPV lungs due to FOXF1 deficiency

Justyna A. Karolak, Tomasz Gambin, Przemyslaw Szafranski, Rebecca L. Maywald, Edwina Popek, Jason D. Heaney, Paweł Stankiewicz

Respir Res. 2021; 22: 212. Published online 2021 Jul 27. doi: 10.1186/s12931-021-01797-7

PMCID:: PMC8314029

Abstract Article PDF–1.2M

Select item 828478311.

Lung-specific distant enhancer cis-regulates expression of FOXF1 and lncRNA FENDRR

Przemyslaw Szafranski, Tomasz Gambin, Justyna A. Karolak, Edwina Popek, Paweł Stankiewicz

Hum Mutat. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Hum Mutat. 2021 Jun; 42(6): 694–698. Published online 2021 Apr 6. doi: 10.1002/humu.24198

PMCID:: PMC8284783

Abstract Article PDF–563K

Select item 826219312.

FOXF1 as an Immunohistochemical Marker of Hilar Cholangiocarcinoma or Metastatic Pancreatic Ductal Adenocarcinoma. Single Institution Experience

Jan Hrudka, Zuzana Prouzová, Katarína Mydlíková, Kristína Jedličková, Michal Holešta, Adam Whitley, Lukáš Havlůj

Pathol Oncol Res. 2021; 27: 1609756. Published online 2021 Apr 20. doi: 10.3389/pore.2021.1609756

PMCID:: PMC8262193

Abstract Article PDF–4.0M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 800549214.

FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma.

David Milewski, Samriddhi Shukla, Berkley E. Gryder, Arun Pradhan, Johnny Donovan, Parvathi Sudha, Sushmitha Vallabh, Athena Pyros, Yan Xu, Artem Barski, Sara Szabo, Brian Turpin, Joseph G. Pressey, Douglas P. Millay, Javed Khan, Vladimir V. Kalinichenko, Tanya V. Kalin

Oncogene. Author manuscript; available in PMC 2021 Aug 24.

Published in final edited form as: Oncogene. 2021 Mar; 40(12): 2182–2199. Published online 2021 Feb 24. doi: 10.1038/s41388-021-01694-9

PMCID:: PMC8005492

Abstract Article PDF–2.8M

Select item 771826915.

Loss of FOXF1 expression promotes human lung-resident mesenchymal stromal cell migration via ATX/LPA/LPA1 signaling axis

Pengxiu Cao, Natalie M. Walker, Russell R. Braeuer, Serina Mazzoni-Putman, Yoshiro Aoki, Keizo Misumi, David S. Wheeler, Ragini Vittal, Vibha N. Lama

Sci Rep. 2020; 10: 21231. Published online 2020 Dec 4. doi: 10.1038/s41598-020-77601-1

PMCID:: PMC7718269

Abstract Article PDF–1.7M

Select item 750512516.

Prognostic impact of FOXF1 polymorphisms in gastric cancer patients

S Matsusaka, AH Wu, S Cao, DL Hanna, K Chin, D Yang, W Zhang, Y Ning, S Stintzing, A Sebio, Y Sunakawa, S Stremitzer, S Yamauchi, S Okazaki, MD Berger, A Parekh, Y Miyamoto, N Mizunuma, H-J Lenz

Pharmacogenomics J. Author manuscript; available in PMC 2020 Sep 21.

Published in final edited form as: Pharmacogenomics J. 2018 Apr; 18(2): 262–269. Published online 2017 Apr 11. doi: 10.1038/tpj.2017.9

PMCID:: PMC7505125

Abstract Article PDF–558K

Select item 743052817.

Heterotrimeric G Stimulatory Protein α Subunit Is Required for Intestinal Smooth Muscle Contraction in Mice

Xiaoteng Qin, Shangming Liu, Qiulun Lu, Meng Zhang, Xiuxin Jiang, Sanyuan Hu, Jingxin Li, Cheng Zhang, Jiangang Gao, Min-Sheng Zhu, Robert Feil, Huashun Li, Min Chen, Lee S. Weinstein, Yun Zhang, Wencheng Zhang

Gastroenterology. Author manuscript; available in PMC 2020 Aug 17.

Published in final edited form as: Gastroenterology. 2017 Apr; 152(5): 1114–1125.e5. Published online 2016 Dec 30. doi: 10.1053/j.gastro.2016.12.017

PMCID:: PMC7430528

Abstract Article PDF–1.9M

Select item 724675218.

Highly Expressed FOXF1 Inhibit Non-Small-Cell Lung Cancer Growth via Inducing Tumor Suppressor and G1-Phase Cell-Cycle Arrest

Chia-Yu Wu, Chun-Hao Chan, Navneet Kumar Dubey, Hong-Jian Wei, Jui-Hua Lu, Chun-Chao Chang, Hsin-Chung Cheng, Keng-Liang Ou, Win-Ping Deng

Int J Mol Sci. 2020 May; 21(9): 3227. Published online 2020 May 2. doi: 10.3390/ijms21093227

PMCID:: PMC7246752

Abstract Article PDF–3.7M

Select item 719386619.

Highly Sensitive Blocker Displacement Amplification and Droplet Digital PCR Reveal Low-Level Parental FOXF1 Somatic Mosaicism in Families with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins

Justyna A. Karolak, Qian Liu, Nina G. Xie, Lucia R. Wu, Gustavo Rocha, Susana Fernandes, Luk Ho-Ming, Ivan F. Lo, David Mowat, Elizabeth K. Fiorino, Morris Edelman, Joyce Fox, Denise A. Hayes, David Witte, Ashley Parrott, Edwina Popek, Przemyslaw Szafranski, David Y. Zhang, Pawel Stankiewicz

J Mol Diagn. 2020 Apr; 22(4): 447–456. doi: 10.1016/j.jmoldx.2019.12.007

PMCID:: PMC7193866

Abstract Article PDF–912K

Select item 711535820.

Epigenetic activation of FOXF1 confers cancer stem cell properties to cisplatin-resistant non-small cell lung cancer

Jian Zhao, Xingyang Xue, Wenfan Fu, Lu Dai, Zeyong Jiang, Shengpeng Zhong, Boyun Deng, Jun Yin

Int J Oncol. 2020 May; 56(5): 1083–1092. Published online 2020 Mar 4. doi: 10.3892/ijo.2020.5003

PMCID:: PMC7115358

Abstract Article PDF–1.8M

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