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Items: 1 to 20 of 41

1.
Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA
Sultan Alanazi, Mirjana Grujic, Maria Lampinen, Ola Rollman, Christian P. Sommerhoff, Gunnar Pejler, Fabio Rabelo Melo
Int J Mol Sci. 2020 Jul; 21(14): 5065. Published online 2020 Jul 17. doi: 10.3390/ijms21145065
PMCID:
PMC7404274
AbstractArticlePDF–2.4M
2.
Hereditary α tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis
Georg Greiner, Bettina Sprinzl, Aleksandra Górska, Franz Ratzinger, Michael Gurbisz, Nadine Witzeneder, Klaus G. Schmetterer, Bettina Gisslinger, Goekhan Uyanik, Emir Hadzijusufovic, Harald Esterbauer, Karoline V. Gleixner, Maria T. Krauth, Michael Pfeilstöcker, Felix Keil, Heinz Gisslinger, Boguslaw Nedoszytko, Marek Niedoszytko, Wolfgang R. Sperr, Peter Valent, Gregor Hoermann
Blood. Author manuscript; available in PMC 2022 Jan 14.
Published in final edited form as: Blood. 2021 Jan 14; 137(2): 238–247. doi: 10.1182/blood.2020006157
PMCID:
PMC7116780
AbstractArticlePDF–1.1M
3.
Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia
Quang T. Le, Jonathan J. Lyons, Andrea N. Naranjo, Ana Olivera, Robert A. Lazarus, Dean D. Metcalfe, Joshua D. Milner, Lawrence B. Schwartz
J Exp Med. 2019 Oct 7; 216(10): 2348–2361. Published online 2019 Jul 23. doi: 10.1084/jem.20190701
PMCID:
PMC6780998
AbstractArticlePDF–2.2M
4.
Adipose Tissue Mast Cells Promote Human Adipose Beiging in Response to Cold
Brian S. Finlin, Amy L. Confides, Beibei Zhu, Mary C. Boulanger, Hasiyet Memetimin, Kyle W. Taylor, Zachary R. Johnson, Philip M. Westgate, Esther E. Dupont-Versteegden, Philip A. Kern
Sci Rep. 2019; 9: 8658. Published online 2019 Jun 17. doi: 10.1038/s41598-019-45136-9
PMCID:
PMC6572779
AbstractArticlePDF–2.0M
5.
BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression
Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-François Rual, James Douglas Engel
Genes Dev. 2018 Dec 1; 32(23-24): 1537–1549. doi: 10.1101/gad.318436.118
PMCID:
PMC6295165
AbstractArticlePDF–3.5M
6.
Dual functionality of β-tryptase protomers as both proteases and cofactors in the active tetramer
Henry R. Maun, Peter S. Liu, Yvonne Franke, Charles Eigenbrot, William F. Forrest, Lawrence B. Schwartz, Robert A. Lazarus
J Biol Chem. 2018 Jun 22; 293(25): 9614–9628. Published online 2018 Apr 16. doi: 10.1074/jbc.M117.812016
PMCID:
PMC6016454
AbstractArticlePDF–1.4M
7.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
8.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
9.
Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number
Jonathan J Lyons, Xiaomin Yu, Jason D Hughes, Quang T Le, Ali Jamil, Yun Bai, Nancy Ho, Ming Zhao, Yihui Liu, Michael P O’Connell, Neil N Trivedi, Celeste Nelson, Thomas DiMaggio, Nina Jones, Helen Matthews, Katie L Lewis, Andrew J Oler, Ryan J Carlson, Peter D Arkwright, Celine Hong, Sherene Agama, Todd M Wilson, Sofie Tucker, Yu Zhang, Joshua J McElwee, Maryland Pao, Sarah C Glover, Marc E Rothenberg, Robert J Hohman, Kelly D Stone, George H Caughey, Theo Heller, Dean D Metcalfe, Leslie G Biesecker, Lawrence B Schwartz, Joshua D Milner
Nat Genet. Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: Nat Genet. 2016 Dec; 48(12): 1564–1569. Published online 2016 Oct 17. doi: 10.1038/ng.3696
PMCID:
PMC5397297
AbstractArticlePDF–484K
10.
Assessment of clinical findings, tryptase levels, and bone marrow histopathology in the management of pediatric mastocytosis
Melody C. Carter, Sarah T. Clayton, Hirsh D. Komarow, Erica H. Brittain, Linda M. Scott, Daly Cantave, Donna M. Gaskins, Irina Maric, Dean D. Metcalfe
J Allergy Clin Immunol. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: J Allergy Clin Immunol. 2015 Dec; 136(6): 1673–79.e1-3. Published online 2015 Jun 1. doi: 10.1016/j.jaci.2015.04.024
PMCID:
PMC4984538
AbstractArticlePDF–636K
11.
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins
Javier Barallobre-Barreiro, Rahmi Oklu, Marc Lynch, Marika Fava, Ferheen Baig, Xiaoke Yin, Temo Barwari, David N. Potier, Hassan Albadawi, Marjan Jahangiri, Karen E. Porter, Michael T. Watkins, Sanjay Misra, Julianne Stoughton, Manuel Mayr
Cardiovasc Res. 2016 Jun 1; 110(3): 419–430. Published online 2016 Apr 11. doi: 10.1093/cvr/cvw075
PMCID:
PMC4872879
AbstractArticlePDF–1.1M
12.
Elevated Serum Tryptase and Endothelin in Patients with ST Segment Elevation Myocardial Infarction: Preliminary Report
Lukasz Lewicki, Janusz Siebert, Natalia Marek-Trzonkowska, Emilia Masiewicz, Tomasz Kolinski, Magdalena Reiwer-Gostomska, Radoslaw Targonski, Piotr Trzonkowski
Mediators Inflamm. 2015; 2015: 395173. Published online 2015 May 18. doi: 10.1155/2015/395173
PMCID:
PMC4452104
AbstractArticlePDF–634K
13.
Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma
A M Abdelmotelb, M J Rose-Zerilli, S J Barton, S T Holgate, A F Walls, J W Holloway
Clin Exp Allergy. 2013 Jun; 44(6): 822–830. Published online 2013 May 24. doi: 10.1111/cea.12259
PMCID:
PMC4282335
AbstractArticlePDF–300K
14.
Development of Mast Cells and Importance of Their Tryptase and Chymase Serine Proteases in Inflammation and Wound Healing
Jeffrey Douaiher, Julien Succar, Luca Lancerotto, Michael F. Gurish, Dennis P. Orgill, Matthew J. Hamilton, Steven A. Krilis, Richard L. Stevens
Adv Immunol. Author manuscript; available in PMC 2014 Jul 29.
Published in final edited form as: Adv Immunol. 2014; 122: 211–252. doi: 10.1016/B978-0-12-800267-4.00006-7
PMCID:
PMC4115062
AbstractArticlePDF–821K
15.
Tryptase - PAR2 axis in Experimental Autoimmune Prostatitis, a model for Chronic Pelvic Pain Syndrome
Kenny Roman, Joseph D. Done, Anthony J. Schaeffer, Stephen F. Murphy, Praveen Thumbikat
Pain. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: Pain. 2014 Jul; 155(7): 1328–1338. Published online 2014 Apr 13. doi: 10.1016/j.pain.2014.04.009
PMCID:
PMC4089501
AbstractArticlePDF–789K
16.
Correlation between Serum Tryptase, Mast Cells Positive to Tryptase and Microvascular Density in Colo-Rectal Cancer Patients: Possible Biological-Clinical Significance
Michele Ammendola, Rosario Sacco, Giuseppe Sammarco, Giuseppe Donato, Severino Montemurro, Eustachio Ruggieri, Rosa Patruno, Ilaria Marech, Marica Cariello, Angelo Vacca, Cosmo Damiano Gadaleta, Girolamo Ranieri
PLoS One. 2014; 9(6): e99512. Published online 2014 Jun 10. doi: 10.1371/journal.pone.0099512
PMCID:
PMC4051753
AbstractArticlePDF–1.0M
17.
Circulating Tryptase as a Marker for Subclinical Atherosclerosis in Obese Subjects
María Moreno, Josep Puig, Marta Serrano, José María Moreno-Navarrete, Francisco Ortega, Wifredo Ricart, Jose Manuel Fernandez-Real
PLoS One. 2014; 9(5): e97014. Published online 2014 May 15. doi: 10.1371/journal.pone.0097014
PMCID:
PMC4022630
AbstractArticlePDF–380K
18.
Neovascularization and mast cells with tryptase activity increase simultaneously in human pterygium
Domenico Ribatti, Beatrice Nico, Cristina Maxia, Vito Longo, Daniela Murtas, Domenica Mangieri, M Teresa Perra, Michela De Giorgis, Franca Piras, Enrico Crivellato, Paola Sirigu
J Cell Mol Med. 2007 May; 11(3): 585–589. Published online 2007 Jul 13. doi: 10.1111/j.1582-4934.2007.00050.x
PMCID:
PMC3922365
AbstractArticlePDF–119K
19.
Serum Tryptase Monitoring in Indolent Systemic Mastocytosis: Association with Disease Features and Patient Outcome
Almudena Matito, José Mario Morgado, Iván Álvarez-Twose, Laura Sánchez-Muñoz, Carlos Eduardo Pedreira, María Jara-Acevedo, Cristina Teodosio, Paula Sánchez-López, Elisa Fernández-Núñez, Ricardo Moreno-Borque, Andrés García-Montero, Alberto Orfao, Luis Escribano
PLoS One. 2013; 8(10): e76116. Published online 2013 Oct 14. doi: 10.1371/journal.pone.0076116
PMCID:
PMC3796517
AbstractArticlePDF–449K
20.
High density of tryptase-positive mast cells in human colorectal cancer: a poor prognostic factor related to protease-activated receptor 2 expression
Andrea Malfettone, Nicola Silvestris, Concetta Saponaro, Girolamo Ranieri, Antonio Russo, Stefano Caruso, Ondina Popescu, Giovanni Simone, Angelo Paradiso, Anita Mangia
J Cell Mol Med. 2013 Aug; 17(8): 1025–1037. Published online 2013 Aug 29. doi: 10.1111/jcmm.12073
PMCID:
PMC3780541
AbstractArticlePDF–1.2M

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