PMC Links for GEO Profiles (Select 122940349) - PMC

Shiwu Zhang, Mengyi Wang, Hongxia Li, Qianzhu Li, Ning Liu, Shiyun Dong, Yajun Zhao, Kemiao Pang, Jiayi Huang, Cheng Ren, Yan Wang, Zhen Tian, Fanghao Lu, Weihua Zhang

J Cachexia Sarcopenia Muscle. 2023 Dec; 14(6): 2719–2732. Published online 2023 Oct 30. doi: 10.1002/jcsm.13347

PMCID:: PMC10751422

Abstract Article PDF–3.4M

Select item 105702964.

Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma

Do-Won Jeong, Jong-Wan Park, Kyeong Seog Kim, Jiyoung Kim, June Huh, Jieun Seo, Ye Lee Kim, Joo-Youn Cho, Kwang-Woong Lee, Junji Fukuda, Yang-Sook Chun

Nat Commun. 2023; 14: 6370. Published online 2023 Oct 12. doi: 10.1038/s41467-023-42170-0

PMCID:: PMC10570296

Abstract Article PDF–3.7M

Select item 98754575.

TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability

Xintian Chen, Hongmei Yong, Miaolei Chen, Chuyin Deng, Pengfei Wang, Sufang Chu, Minle Li, Pingfu Hou, Junnian Zheng, Zhongwei Li, Jin Bai

J Exp Clin Cancer Res. 2023; 42: 34. Published online 2023 Jan 25. doi: 10.1186/s13046-022-02583-z

PMCID:: PMC9875457

Abstract Article PDF–13M

Select item 96332856.

Apelin‐mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis

Yihan Zhu, Ying Yang, Hong Bu, Hong Huang, Hongyu Chen, Jingjing Ran, Liwen Qin, Yinyun Ni, Menglin Yao, Tingting Song, Mufeng Li, Yongfeng Yang, Tingting Guo, Ningning Chao, Zhiqing Liu, Weimin Li, Li Zhang

Cancer Sci. 2022 Nov; 113(11): 3722–3734. Published online 2022 Sep 10. doi: 10.1111/cas.15515

PMCID:: PMC9633285

Abstract Article PDF–12M

Select item 93383137.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 92626148.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 92316239.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 914616210.

Leptin Silencing Attenuates Lipid Accumulation through Sterol Regulatory Element-Binding Protein 1 Inhibition in Nasopharyngeal Carcinoma

Sheng-Dean Luo, Hsin-Ting Tsai, Tai-Jan Chiu, Shau-Hsuan Li, Ya-Ling Hsu, Li-Jen Su, Meng-Hsiu Tsai, Ching-Yi Lee, Chang-Chun Hsiao, Chang-Han Chen

Int J Mol Sci. 2022 May; 23(10): 5700. Published online 2022 May 20. doi: 10.3390/ijms23105700

PMCID:: PMC9146162

Abstract Article PDF–2.1M

Select item 889702211.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 880664712.

Long intergenic non-protein coding RNA 02570 promotes nasopharyngeal carcinoma progression by adsorbing microRNA miR-4649-3p thereby upregulating both sterol regulatory element binding protein 1, and fatty acid synthase

Fei Liu, Jiazhang Wei, Yanrong Hao, Jiao Lan, Wei Li, Jingjin Weng, Min Li, Cheng Su, Bing Li, Mingzheng Mo, Fengzhu Tang, Yongli Wang, Yong Yang, Wei Jiao, Shenhong Qu

Bioengineered. 2021; 12(1): 7108–7119. Published online 2021 Sep 21. doi: 10.1080/21655979.2021.1979317

PMCID:: PMC8806647

Abstract Article PDF–2.8M

Select item 867136613.

Induction of SREBP1 degradation coupled with suppression of SREBP1-mediated lipogenesis impacts the response of EGFR mutant NSCLC cells to osimertinib

Zhen Chen, Danlei Yu, Taofeek K. Owonikoko, Suresh S. Ramalingam, Shi-Yong Sun

Oncogene. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Oncogene. 2021 Dec; 40(49): 6653–6665. Published online 2021 Oct 11. doi: 10.1038/s41388-021-02057-0

PMCID:: PMC8671366

Abstract Article PDF–2.7M

Select item 846911814.

SREBP1-Induced Glutamine Synthetase Triggers a Feedforward Loop to Upregulate SREBP1 through Sp1 O-GlcNAcylation and Augments Lipid Droplet Formation in Cancer Cells

Jin-Wei Jhu, Jia-Bao Yan, Zou-Han Lin, Shih-Chieh Lin, I-Chen Peng

Int J Mol Sci. 2021 Sep; 22(18): 9814. Published online 2021 Sep 10. doi: 10.3390/ijms22189814

PMCID:: PMC8469118

Abstract Article PDF–2.3M

Select item 844931115.

Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1

Shilei Zhang, Jingfeng Wang, Genhong Cheng

Proc Natl Acad Sci U S A. 2021 Sep 14; 118(37): e2107108118. Published online 2021 Aug 27. doi: 10.1073/pnas.2107108118

PMCID:: PMC8449311

Abstract Article PDF–1.5M

Select item 835390316.

An AKT/PRMT5/SREBP1 axis in lung adenocarcinoma regulates de novo lipogenesis and tumor growth

Liu Liu, Hui Yan, Maomei Ruan, Hao Yang, Lihua Wang, Bei Lei, Xiaoyan Sun, Cheng Chang, Gang Huang, Wenhui Xie

Cancer Sci. 2021 Aug; 112(8): 3083–3098. Published online 2021 Jun 13. doi: 10.1111/cas.14988

PMCID:: PMC8353903

Abstract Article PDF–2.1M

Select item 833570417.

SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC

Christian F. Ruiz, Emily D. Montal, John A. Haley, Alex J. Bott, John D. Haley

FASEB J. Author manuscript; available in PMC 2021 Aug 4.

Published in final edited form as: FASEB J. 2020 Aug; 34(8): 10574–10589. Published online 2020 Jun 22. doi: 10.1096/fj.202000052R

PMCID:: PMC8335704

Abstract Article PDF–2.1M

Select item 828554218.

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer

Li-Yan Li, Qian Yang, Yan-Yi Jiang, Wei Yang, Yuan Jiang, Xiang Li, Masaharu Hazawa, Bo Zhou, Guo-Wei Huang, Xiu-E Xu, Sigal Gery, Ying Zhang, Ling-Wen Ding, Allen S. Ho, Zachary S. Zumsteg, Ming-Rong Wang, Melissa J. Fullwood, Stephen J. Freedland, Stephen J. Meltzer, Li-Yan Xu, En-Min Li, H. Phillip Koeffler, De-Chen Lin

Nat Commun. 2021; 12: 4362. Published online 2021 Jul 16. doi: 10.1038/s41467-021-24656-x

PMCID:: PMC8285542

Abstract Article PDF–16M

Select item 817848819.

DNA methylome analysis identifies BMI‐related epigenetic changes associated with non‐small cell lung cancer susceptibility

Guyanan Li, Hua Meng, Yansen Bai, Wei Wei, Yue Feng, Mengying Li, Hang Li, Meian He, Xiaomin Zhang, Sheng Wei, Yangkai Li, Huan Guo

Cancer Med. 2021 Jun; 10(11): 3770–3781. Published online 2021 May 3. doi: 10.1002/cam4.3906

PMCID:: PMC8178488

Abstract Article PDF–1017K

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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