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Select item 110433761.

ATF3 characterizes aggressive drug-tolerant persister cells in HGSOC

Kathrin Böpple, Yaara Oren, Whitney S. Henry, Meng Dong, Sandra Weller, Julia Thiel, Markus Kleih, Andrea Gaißler, Damaris Zipperer, Hans-Georg Kopp, Yael Aylon, Moshe Oren, Frank Essmann, Chunguang Liang, Walter E. Aulitzky

Cell Death Dis. 2024 Apr; 15(4): 290. Published online 2024 Apr 24. doi: 10.1038/s41419-024-06674-x

PMCID:: PMC11043376

Abstract Article PDF–3.4M

Select item 109332672.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 108937013.

Role of ATF3 triggering M2 macrophage polarization to protect against the inflammatory injury of sepsis through ILF3/NEAT1 axis

Wei Wang, Rongli Xu, Ping He, Yuqing Xiong, Haomiao Zhao, Xuewei Fu, Jie Lin, Lijiao Ye

Mol Med. 2024; 30: 30. Published online 2024 Feb 23. doi: 10.1186/s10020-023-00711-9

PMCID:: PMC10893701

Abstract Article PDF–14M

Select item 108049304.

Activating transcription factor 3 is a new biomarker correlation with renal clear cell carcinoma progression

Zhicong Yang, Yongwang Hou, Jingqi Li, Dandan Xu, Zhichao Yang, Xinsheng Wang

Int J Immunopathol Pharmacol. 2024 Jan-Dec; 38: 03946320241227320. Published online 2024 Jan 22. doi: 10.1177/03946320241227320

PMCID:: PMC10804930

Abstract Article PDF–2.0M

Select item 105760325.

Identification of ATF3 as a novel protective signature of quiescent colorectal tumor cells

Xi Lu, Lei Zhong, Emma Lindell, Margus Veanes, Jing Guo, Miao Zhao, Maede Salehi, Fredrik J. Swartling, Xingqi Chen, Tobias Sjöblom, Xiaonan Zhang

Cell Death Dis. 2023 Oct; 14(10): 676. Published online 2023 Oct 13. doi: 10.1038/s41419-023-06204-1

PMCID:: PMC10576032

Abstract Article PDF–4.9M

Select item 105658766.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 103126747.

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B. Maseko, Soon Gang Choi, Jeremy Blavier, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A. Calderwood, David E. Hill, Markus Landthaler, Julien Olivet, Jean-Claude Twizere, Marc Vidal, Erich E. Wanker

Version 1. bioRxiv. Preprint. 2023 Jun 14. doi: 10.1101/2023.06.14.544560

Published in:: Mol Syst Biol. 2024 Apr; 20(4): 428–457.

PMCID:: PMC10312674

Abstract Article PDF–9.6M

Select item 100761838.

Activating transcription factor 3, glucolipid metabolism, and metabolic diseases

Shuwei Hu, Xiaojie Zhao, Rui Li, Chencheng Hu, Huijuan Wu, Jing Li, Yanqiao Zhang, Yanyong Xu

J Mol Cell Biol. 2022 Oct; 14(10): mjac067. Published online 2022 Dec 6. doi: 10.1093/jmcb/mjac067

PMCID:: PMC10076183

Abstract Article PDF–924K

Select item 98111579.

ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation

Milena Perrone, Claudia Chiodoni, Mara Lecchi, Laura Botti, Barbara Bassani, Annamaria Piva, Elena Jachetti, Matteo Milani, Daniele Lecis, Elda Tagliabue, Paolo Verderio, Sabina Sangaletti, Mario P. Colombo

Cancer Res. 2023 Jan 4; 83(1): 117–129. Published online 2022 Nov 1. doi: 10.1158/0008-5472.CAN-22-0651

PMCID:: PMC9811157

Abstract Article PDF–39M

Select item 962906410.

ATF3 -activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in pulmonary fibrosis

Jinjin Zhang, Haixia Wang, Hongbin Chen, Hongbo Li, Pan Xu, Bo Liu, Qian Zhang, Changjun Lv, Xiaodong Song

Autophagy. 2022; 18(11): 2636–2655. Published online 2022 Apr 15. doi: 10.1080/15548627.2022.2046448

PMCID:: PMC9629064

Abstract Article PDF–6.4M

Select item 911973611.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 896588812.

Nuclear Receptor PXR Confers Irradiation Resistance by Promoting DNA Damage Response Through Stabilization of ATF3

Xiaxia Niu, Hongmei Cui, Xinsheng Gu, Ting Wu, Min Sun, Changlong Zhou, Mei Ma

Front Oncol. 2022; 12: 837980. Published online 2022 Mar 16. doi: 10.3389/fonc.2022.837980

PMCID:: PMC8965888

Abstract Article PDF–5.4M

Select item 882114513.

Induction of heparanase 2 (Hpa2) expression by stress is mediated by ATF3

Ibrahim Knani, Preeti Singh, Miriam Gross-Cohen, Sharon Aviram, Neta Ilan, Ralph D Sanderson, Ami Aronheim, Israel Vlodavsky

Matrix Biol. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Matrix Biol. 2022 Jan; 105: 17–30. Published online 2021 Nov 20. doi: 10.1016/j.matbio.2021.11.001

PMCID:: PMC8821145

Abstract Article PDF–1.9M

Select item 880632414.

Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway

Xue-Ming Wang, Xiu-Mei Liu, Yuting Wang, Zhen-Yu Chen

Bioengineered. 2021; 12(1): 117–126. Published online 2020 Dec 23. doi: 10.1080/21655979.2020.1860491

PMCID:: PMC8806324

Abstract Article PDF–4.2M

Select item 875667515.

ATF3 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an N⁶‑Methyladenosine-Based Epitranscriptomic Mechanism

Xiaochuan Liu, Jun Yuan, Xudong Zhang, Lin Li, Xiaoxia Dai, Qi Chen, Yinsheng Wang

Chem Res Toxicol. Author manuscript; available in PMC 2022 Jul 19.

Published in final edited form as: Chem Res Toxicol. 2021 Jul 19; 34(7): 1814–1821. Published online 2021 Jul 2. doi: 10.1021/acs.chemrestox.1c00206

PMCID:: PMC8756675

Abstract Article PDF–1.2M

Select item 863975016.

Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP

Guohua Xie, Ping Dong, Hui Chen, Ling Xu, Yi Liu, Yanhui Ma, Yingxia Zheng, Junyao Yang, Yunlan Zhou, Lei Chen, Lisong Shen

Exp Mol Med. 2021 Nov; 53(11): 1706–1722. Published online 2021 Nov 2. doi: 10.1038/s12276-021-00694-9

PMCID:: PMC8639750

Abstract Article PDF–7.9M

Select item 862939017.

ATRX proximal protein associations boast roles beyond histone deposition

William A. Scott, Erum Z. Dhanji, Boris J. A. Dyakov, Ema S. Dreseris, Jonathon S. Asa, Laura J. Grange, Mila Mirceta, Christopher E. Pearson, Grant S. Stewart, Anne-Claude Gingras, Eric I. Campos

PLoS Genet. 2021 Nov; 17(11): e1009909. Published online 2021 Nov 15. doi: 10.1371/journal.pgen.1009909

PMCID:: PMC8629390

Abstract Article PDF–4.0M

Select item 858378418.

Forkhead Box Protein P3 (FOXP3) Represses ATF3 Transcriptional Activity

Chiung-Min Wang, William Harry Yang, Leticia Cardoso, Ninoska Gutierrez, Richard Henry Yang, Wei-Hsiung Yang

Int J Mol Sci. 2021 Nov; 22(21): 11400. Published online 2021 Oct 22. doi: 10.3390/ijms222111400

PMCID:: PMC8583784

Abstract Article PDF–1.0M

Select item 849109819.

ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

Xingyao Li, Daniel Gracilla, Lun Cai, Mingyi Zhang, Xiaolin Yu, Xiaoguang Chen, Junran Zhang, Xiaochun Long, Han-Fei Ding, Chunhong Yan

Cell Rep. Author manuscript; available in PMC 2021 Oct 5.

Published in final edited form as: Cell Rep. 2021 Sep 21; 36(12): 109706. doi: 10.1016/j.celrep.2021.109706

PMCID:: PMC8491098

Abstract Article PDF–2.2M

Select item 846353420.

ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron

Shan Lu, Xuan-zhong Wang, Chuan He, Lei Wang, Shi-peng Liang, Chong-cheng Wang, Chen Li, Tian-fei Luo, Chun-sheng Feng, Zhen-chuan Wang, Guang-fan Chi, Peng-fei Ge

Acta Pharmacol Sin. 2021 Oct; 42(10): 1690–1702. Published online 2021 Jun 10. doi: 10.1038/s41401-021-00700-w

PMCID:: PMC8463534

Abstract Article PDF–7.4M

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