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Select item 111689331.

A disease-associated gene desert directs macrophage inflammation through ETS2

C. T. Stankey, C. Bourges, L. M. Haag, T. Turner-Stokes, A. P. Piedade, C. Palmer-Jones, I. Papa, M. Silva dos Santos, Q. Zhang, A. J. Cameron, A. Legrini, T. Zhang, C. S. Wood, F. N. New, L. O. Randzavola, L. Speidel, A. C. Brown, A. Hall, F. Saffioti, E. C. Parkes, W. Edwards, H. Direskeneli, P. C. Grayson, L. Jiang, P. A. Merkel, G. Saruhan-Direskeneli, A. H. Sawalha, E. Tombetti, A. Quaglia, D. Thorburn, J. C. Knight, A. P. Rochford, C. D. Murray, P. Divakar, M. Green, E. Nye, J. I. MacRae, N. B. Jamieson, P. Skoglund, M. Z. Cader, C. Wallace, D. C. Thomas, J. C. Lee

Nature. 2024; 630(8016): 447–456. Published online 2024 Jun 5. doi: 10.1038/s41586-024-07501-1

PMCID:: PMC11168933

Abstract Article PDF–45M

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 106046583.

USP39-Mediated Non-Proteolytic Control of ETS2 Suppresses Nuclear Localization and Activity

Yunsik Choi, Yuri Lee, Jin Seo Kim, Peijing Zhang, Jongchan Kim

Biomolecules. 2023 Oct; 13(10): 1475. Published online 2023 Oct 1. doi: 10.3390/biom13101475

PMCID:: PMC10604658

Abstract Article PDF–4.2M

Select item 93485764.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 83071945.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 80500536.

A novel tissue specific alternative splicing variant mitigates phenotypes in Ets2 frame-shift mutant models

Yuki Kishimoto, Iori Nishiura, Wataru Hirata, Shunsuke Yuri, Nami Yamamoto, Masahito Ikawa, Ayako Isotani

Sci Rep. 2021; 11: 8297. Published online 2021 Apr 15. doi: 10.1038/s41598-021-87751-5

PMCID:: PMC8050053

Abstract Article PDF–1.3M

Select item 80090487.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 74905608.

A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation

Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson

Redox Biol. 2020 Oct; 37: 101686. Published online 2020 Aug 20. doi: 10.1016/j.redox.2020.101686

PMCID:: PMC7490560

Abstract Article PDF–8.6M

Select item 70584459.

ΔNp73/ETS2 complex drives glioblastoma pathogenesis— targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma

Maren Cam, Manish Charan, Alessandra M Welker, Piyush Dravid, Adam W Studebaker, Jeffrey R Leonard, Christopher R Pierson, Ichiro Nakano, Christine E Beattie, Eugene I Hwang, Madhuri Kambhampati, Javad Nazarian, Jonathan L Finlay, Hakan Cam

Neuro Oncol. 2020 Mar; 22(3): 345–356. Published online 2019 Nov 25. doi: 10.1093/neuonc/noz190

PMCID:: PMC7058445

Abstract Article PDF–774K

Select item 681850310.

ETS2 is a prostate basal cell marker and is highly expressed in prostate cancers aberrantly expressing p63

Alba Torres, Mohammed Alshalalfa, Elai Davicioni, Anuj Gupta, Srinivasan Yegnasubramanian, Sarah J. Wheelan, Jonathan I. Epstein, Angelo M. De Marzo, Tamara L. Lotan

Prostate. Author manuscript; available in PMC 2019 Oct 29.

Published in final edited form as: Prostate. 2018 Sep; 78(12): 896–904. Published online 2018 May 15. doi: 10.1002/pros.23646

PMCID:: PMC6818503

Abstract Article PDF–2.3M

Select item 669419211.

Association of Cyclin Dependent Kinase 10 and Transcription Factor 2 during Human Corneal Epithelial Wound Healing in vitro model

Meraj Zehra, Shamim Mushtaq, Syed Ghulam Musharraf, Rubina Ghani, Nikhat Ahmed

Sci Rep. 2019; 9: 11802. Published online 2019 Aug 14. doi: 10.1038/s41598-019-48092-6

Correction in:: Sci Rep. 2020; 10: 14405.

PMCID:: PMC6694192

Abstract Article PDF–4.1M

Select item 642409812.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

Select item 604383313.

Differential Allelic Distribution of V-ets Erythroblastosis Virus E26 Oncogene Homolog2 (ETS2) Functional Polymorphisms in Different Group of Patients

Arpita Chatterjee, Samikshan Dutta, Sanjit Mukherjee, Nupur Mukherjee, Sharmila Chandra, Ashis Mukherjee, Swagata Sinha, Chinmay Kumar Panda, Keya Chaudhuri, Kanchan Mukhopadyay

Gene Expr. 2011; 15(2): 61–73. Published online 2018 Jul 13. doi: 10.3727/105221611x12973615737541

PMCID:: PMC6043833

Abstract Article PDF–767K

Select item 551816114.

High expression of ETS2 predicts poor prognosis in acute myeloid leukemia and may guide treatment decisions

Lin Fu, Huaping Fu, Qingyun Wu, Yifan Pang, Keman Xu, Lei Zhou, Jianlin Qiao, Xiaoyan Ke, Kailin Xu, Jinlong Shi

J Transl Med. 2017; 15: 159. Published online 2017 Jul 19. doi: 10.1186/s12967-017-1260-2

PMCID:: PMC5518161

Abstract Article PDF–1.4M

Select item 541675315.

Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2

Joshua P. Plotnik, Peter C. Hollenhorst

Nucleic Acids Res. 2017 May 5; 45(8): 4452–4462. Published online 2017 Jan 24. doi: 10.1093/nar/gkx039

PMCID:: PMC5416753

Abstract Article PDF–2.9M

Select item 530866416.

Ets2 knockdown inhibits tumorigenesis in esophageal squamous cell carcinoma in vivo and in vitro

Qinghua Li, Lu Yang, Kang Han, Liqiang Zhu, Yanting Zhang, Shanshan Ma, Kun Zhang, Bo Yang, Fangxia Guan

Oncotarget. 2016 Sep 20; 7(38): 61458–61468. Published online 2016 Aug 18. doi: 10.18632/oncotarget.11369

PMCID:: PMC5308664

Abstract Article PDF–2.6M

Select item 503186717.

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia

Jason R. Pitarresi, Xin Liu, Sudarshana M. Sharma, Maria C. Cuitiño, Raleigh D. Kladney, Thomas A. Mace, Sydney Donohue, Sunayana G. Nayak, Chunjing Qu, James Lee, Sarah A. Woelke, Stefan Trela, Kyle LaPak, Lianbo Yu, Joseph McElroy, Thomas J. Rosol, Reena Shakya, Thomas Ludwig, Gregory B. Lesinski, Soledad A. Fernandez, Stephen F. Konieczny, Gustavo Leone, Jinghai Wu, Michael C. Ostrowski

Neoplasia. 2016 Sep; 18(9): 541–552. Published online 2016 Sep 20. doi: 10.1016/j.neo.2016.07.006

PMCID:: PMC5031867

Abstract Article PDF–3.3M

Select item 494128918.

A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer

Mi Jeong Hong, Shin Yup Lee, Jin Eun Choi, Cheng Cheng Jin, Hyo Jung Kang, Sun Ah Baek, So Yeon Lee, Kyung Min Shin, Ji Yun Jeong, Won Kee Lee, Seung Soo Yoo, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Ji Woong Son, Jae Yong Park

Oncotarget. 2016 Mar 29; 7(13): 15948–15958. Published online 2016 Feb 17. doi: 10.18632/oncotarget.7433

PMCID:: PMC4941289

Abstract Article PDF–2.2M

Select item 491430419.

Mutant p53 protects ETS2 from non-canonical COP1/DET1 dependent degradation

Zunamys I. Carrero, Madhusudhan Kollareddy, Krishna M. Chauhan, Gopalakrishnan Ramakrishnan, Luis A. Martinez

Oncotarget. 2016 Mar 15; 7(11): 12554–12567. Published online 2016 Feb 9. doi: 10.18632/oncotarget.7275

PMCID:: PMC4914304

Abstract Article PDF–5.6M

Select item 488846720.

ETS2 and Twist1 promote invasiveness of Helicobacter pylori-infected gastric cancer cells by inducing Siah2

Lopamudra Das, Shrikant Babanrao Kokate, Suvasmita Rath, Niranjan Rout, Shivaram Prasad Singh, Sheila Eileen Crowe, Asish K. Mukhopadhyay, Asima Bhattacharyya

Biochem J. 2016 Jun 1; 473(11): 1629–1640. Prepublished online 2016 Apr 5. Published online 2016 May 27. doi: 10.1042/BCJ20160187

PMCID:: PMC4888467

Abstract Article PDF–1.1M

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