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Select item 110128411.

The Catalytic Activity of Human REV1 on Undamaged and Damaged DNA

Anastasia D. Stolyarenko, Anna A. Novikova, Evgeniy S. Shilkin, Valentin A. Poltorachenko, Alena V. Makarova

Int J Mol Sci. 2024 Apr; 25(7): 4107. Published online 2024 Apr 8. doi: 10.3390/ijms25074107

PMCID:: PMC11012841

Abstract Article PDF–2.9M

Select item 102431162.

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification

Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt

J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706

PMCID:: PMC10243116

Abstract Article PDF–13M

Select item 88970223.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 88141794.

REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis

Yunshang Chen, Xiaohua Jie, Biyuan Xing, Zilong Wu, Xijie Yang, Xinrui Rao, Yingzhuo Xu, Dong Zhou, Xiaorong Dong, Tao Zhang, Kunyu Yang, Zhenyu Li, Gang Wu

Cell Death Dis. 2022 Feb; 13(2): 110. Published online 2022 Feb 3. doi: 10.1038/s41419-022-04567-5

PMCID:: PMC8814179

Abstract Article PDF–6.0M

Select item 85609535.

Genetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells

Tonghui Bi, Xiaohong Niu, Chunping Qin, Wei Xiao

Sci Rep. 2021; 11: 21364. Published online 2021 Nov 1. doi: 10.1038/s41598-021-00878-3

PMCID:: PMC8560953

Abstract Article PDF–7.9M

Select item 85009496.

REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps

Angelo Taglialatela, Giuseppe Leuzzi, Vincenzo Sannino, Raquel Cuella-Martin, Jen-Wei Huang, Foon Wu-Baer, Richard Baer, Vincenzo Costanzo, Alberto Ciccia

Mol Cell. Author manuscript; available in PMC 2022 Oct 7.

Published in final edited form as: Mol Cell. 2021 Oct 7; 81(19): 4008–4025.e7. Published online 2021 Sep 10. doi: 10.1016/j.molcel.2021.08.016

PMCID:: PMC8500949

Abstract Article PDF–3.1M

Select item 83529647.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 79136888.

Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs

Amit Ketkar, Lane Smith, Callie Johnson, Alyssa Richey, Makayla Berry, Jessica H Hartman, Leena Maddukuri, Megan R Reed, Julie E C Gunderson, Justin W C Leung, Robert L Eoff

Nucleic Acids Res. 2021 Feb 26; 49(4): 2065–2084. Published online 2021 Feb 8. doi: 10.1093/nar/gkab041

PMCID:: PMC7913688

Abstract Article PDF–5.9M

Select item 73220679.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 702607010.

Exome Sequencing in Individuals with Isolated Biliary Atresia

Ramakrishnan Rajagopalan, Ellen A. Tsai, Christopher M. Grochowski, Susan M. Kelly, Kathleen M. Loomes, Nancy B. Spinner, Marcella Devoto

Sci Rep. 2020; 10: 2709. Published online 2020 Feb 17. doi: 10.1038/s41598-020-59379-4

PMCID:: PMC7026070

Abstract Article PDF–1.0M

Select item 694204511.

Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne

Xiao Wu, Shichang Liu, Cari Sagum, Jianji Chen, Rajesh Singh, Apurva Chaturvedi, John R. Horton, Tanuja R. Kashyap, David Fushman, Xiaodong Cheng, Mark T. Bedford, Bin Wang

Genes Dev. 2019 Dec 1; 33(23-24): 1702–1717. doi: 10.1101/gad.332395.119

PMCID:: PMC6942045

Abstract Article PDF–7.6M

Select item 689239312.

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge

Mol Cell. Author manuscript; available in PMC 2019 Dec 4.

Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008

PMCID:: PMC6892393

Abstract Article PDF–1.7M

Select item 642313913.

DNA polymerase ι is acetylated in response to S_N2 alkylating agents

Justyna McIntyre, Aleksandra Sobolewska, Mikolaj Fedorowicz, Mary P. McLenigan, Matylda Macias, Roger Woodgate, Ewa Sledziewska-Gojska

Sci Rep. 2019; 9: 4789. Published online 2019 Mar 18. doi: 10.1038/s41598-019-41249-3

PMCID:: PMC6423139

Abstract Article PDF–2.8M

Select item 633346014.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 616668215.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 613843916.

SHLD2/FAM35A co‐operates with REV7 to coordinate DNA double‐strand break repair pathway choice

Steven Findlay, John Heath, Vincent M Luo, Abba Malina, Théo Morin, Yan Coulombe, Billel Djerir, Zhigang Li, Arash Samiei, Estelle Simo‐Cheyou, Martin Karam, Halil Bagci, Dolev Rahat, Damien Grapton, Elise G Lavoie, Christian Dove, Husam Khaled, Hellen Kuasne, Koren K Mann, Kathleen Oros Klein, Celia M Greenwood, Yuval Tabach, Morag Park, Jean‐Francois Côté, Jean‐Yves Masson, Alexandre Maréchal, Alexandre Orthwein

EMBO J. 2018 Sep 14; 37(18): e100158. Published online 2018 Aug 28. doi: 10.15252/embj.2018100158

PMCID:: PMC6138439

Abstract Article PDF–1.1M

Select item 612674117.

Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex

Alessandro A. Rizzo, Faye-Marie Vassel, Nimrat Chatterjee, Sanjay D’Souza, Yunfeng Li, Bing Hao, Michael T. Hemann, Graham C. Walker, Dmitry M. Korzhnev

Proc Natl Acad Sci U S A. 2018 Aug 28; 115(35): E8191–E8200. Published online 2018 Aug 15. doi: 10.1073/pnas.1801149115

PMCID:: PMC6126741

Abstract Article PDF–1.7M

Select item 604335218.

Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin

Gaofeng Cui, Maria Victoria Botuyan, Georges Mer

J Mol Biol. Author manuscript; available in PMC 2019 Jul 6.

Published in final edited form as: J Mol Biol. 2018 Jul 6; 430(14): 2042–2050. Published online 2018 May 18. doi: 10.1016/j.jmb.2018.05.017

PMCID:: PMC6043352

Abstract Article PDF–977K

Select item 587256619.

Overexpression of Rev1 promotes the development of carcinogen-induced intestinal adenomas via accumulation of point mutation and suppression of apoptosis proportionally to the Rev1 expression level

Megumi Sasatani, Yang Xi, Junko Kajimura, Toshiyuki Kawamura, Jinlian Piao, Yuji Masuda, Hiroaki Honda, Kei Kubo, Takahiro Mikamoto, Hiromitsu Watanabe, Yanbin Xu, Hidehiko Kawai, Tsutomu Shimura, Asao Noda, Kanya Hamasaki, Yoichiro Kusunoki, Elena Karamfilova Zaharieva, Kenji Kamiya

Carcinogenesis. 2017 May; 38(5): 570–578. Published online 2017 May 9. doi: 10.1093/carcin/bgw208