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Select item 97979881.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 91110302.

Pulmonary endothelial NEDD9 and the prothrombotic pathophenotype of acute respiratory distress syndrome due to SARS‐CoV‐2 infection

George A. Alba, Andriy O. Samokhin, Rui‐Sheng Wang, Bradley M. Wertheim, Kathleen J. Haley, Robert F. Padera, Sara O. Vargas, Ivan O. Rosas, Lida P. Hariri, Angela Shih, Boyd Taylor Thompson, Richard N. Mitchell, Bradley A. Maron

Pulm Circ. 2022 Apr; 12(2): e12071. Published online 2022 May 11. doi: 10.1002/pul2.12071

PMCID:: PMC9111030

Abstract Article PDF–1.6M

Select item 90974193.

miR-107 is involved in the regulation of NEDD9-mediated invasion and metastasis in breast cancer

Jiamin Zhou, Xianglin Sun, Xinyu Zhang, Huan Yang, Zhenglin Jiang, Qianqian Luo, Yifei Liu, Guohua Wang

BMC Cancer. 2022; 22: 533. Published online 2022 May 12. doi: 10.1186/s12885-022-09603-3

PMCID:: PMC9097419

Abstract Article PDF–9.2M

Select item 87690724.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 85009765.

NEDD9 overexpression: Prognostic and guidance value in acute myeloid leukaemia

Shenghao Hua, Tao Feng, Lei Yin, Qi Wang, Xuejun Shao

J Cell Mol Med. 2021 Oct; 25(19): 9331–9339. Published online 2021 Aug 25. doi: 10.1111/jcmm.16870

PMCID:: PMC8500976

Abstract Article PDF–1.6M

Select item 83812096.

Expression of NEDD9 and connexin-43 in neoplastic and stromal cells of gastric adenocarcinoma

Ivan Lerotić, Petra Vuković, Davor Hrabar, Zvonimir Misir, Ivan Kruljac, Jelena Forgač, Petra Ćaćić, Tajana Pavić, Monika Ulamec

Bosn J Basic Med Sci. 2021 Oct; 21(5): 542–548. doi: 10.17305/bjbms.2020.5379

PMCID:: PMC8381209

Abstract Article PDF–606K

Select item 83516757.

MicroRNA-1252-5p, regulated by Myb, inhibits invasion and epithelial-mesenchymal transition of pancreatic cancer cells by targeting NEDD9

Yuzheng Xue, Tielong Wu, Yingyue Sheng, Yao Zhong, Benshun Hu, Chuanqing Bao

Aging (Albany NY) 2021 Jul 31; 13(14): 18924–18945. Published online 2021 Jul 27. doi: 10.18632/aging.203344

PMCID:: PMC8351675

Abstract Article PDF–3.1M

Select item 82862958.

Susceptibility-associated genetic variation in NEDD9 contributes to prostate cancer initiation and progression

Dong Han, Jude N. Owiredu, Bridget M. Healy, Muqing Li, Maryam Labaf, Jocelyn S. Steinfeld, Susan Patalano, Shuai Gao, Mingyu Liu, Jill A. Macoska, Kourosh Zarringhalam, Kellee R. Siegfried, Xin Yuan, Timothy R. Rebbeck, Changmeng Cai

Cancer Res. Author manuscript; available in PMC 2022 Jan 15.

Published in final edited form as: Cancer Res. 2021 Jul 15; 81(14): 3766–3776. Published online 2021 Feb 25. doi: 10.1158/0008-5472.CAN-20-3042

PMCID:: PMC8286295

Abstract Article PDF–2.3M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 783844710.

siRNA Suppression of NEDD9 Inhibits Proliferation and Enhances Apoptosis in Renal Cell Carcinoma

Jue Wang, Wen-juan Yang, Chao Sun, Yun Luan, Guang-hui Cheng, Kai-lin Li, Feng Kong

Oncol Res. 2015; 22(4): 219–224. Published online 2015 Sep 15. doi: 10.3727/096504015X14386062091442

PMCID:: PMC7838447

Abstract Article PDF–5.7M

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 689428312.

ZMYND10, an epigenetically regulated tumor suppressor, exerts tumor-suppressive functions via miR145-5p/NEDD9 axis in breast cancer

Yan Wang, Liangying Dan, Qianqian Li, Lili Li, Lan Zhong, Bianfei Shao, Fang Yu, Sanxiu He, Shaorong Tian, Jin He, Qian Xiao, Thomas C. Putti, Xiaoqian He, Yixiao Feng, Yong Lin, Tingxiu Xiang

Clin Epigenetics. 2019; 11: 184. Published online 2019 Dec 4. doi: 10.1186/s13148-019-0785-z

Correction in:: Clin Epigenetics. 2022; 14: 36.

PMCID:: PMC6894283

Abstract Article PDF–6.4M

Select item 670470113.

SOX2 promotes hypoxia-induced breast cancer cell migration by inducing NEDD9 expression and subsequent activation of Rac1/HIF-1α signaling

Yueyuan Wang, Maria Bibi, Pengxiang Min, Wenjie Deng, Yujie Zhang, Jun Du

Cell Mol Biol Lett. 2019; 24: 55. Published online 2019 Aug 22. doi: 10.1186/s11658-019-0180-y

PMCID:: PMC6704701

Abstract Article PDF–1.3M

Select item 631668714.

Clinical Significance of Serum NEDD9 Levels in Patients with Pancreatic Cancer

Cigdem Usul Afsar, Mehmet Karabulut, Senem Karabulut, Safiye Tokgoz Ozal, Murat Cikot, Murat Serilmez, Faruk Tas

Biomolecules. 2018 Dec; 8(4): 169. Published online 2018 Dec 10. doi: 10.3390/biom8040169

PMCID:: PMC6316687

Abstract Article PDF–782K

Select item 622302515.

NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension

Andriy O. Samokhin, Thomas Stephens, Bradley M. Wertheim, Rui-Sheng Wang, Sara O. Vargas, Lai-Ming Yung, Minwei Cao, Marcel Brown, Elena Arons, Paul B. Dieffenbach, Jason G. Fewell, Majed Matar, Frederick P. Bowman, Kathleen J. Haley, George A. Alba, Stefano M. Marino, Rahul Kumar, Ivan O. Rosas, Aaron B. Waxman, William M. Oldham, Dinesh Khanna, Brian B. Graham, Sachiko Seo, Vadim N. Gladyshev, Paul B. Yu, Laura E. Fredenburgh, Joseph Loscalzo, Jane A. Leopold, Bradley A. Maron

Sci Transl Med. Author manuscript; available in PMC 2018 Dec 13.

Published in final edited form as: Sci Transl Med. 2018 Jun 13; 10(445): eaap7294. doi: 10.1126/scitranslmed.aap7294

PMCID:: PMC6223025

Abstract Article PDF–2.3M

Select item 616085816.

Vimentin and Non-Muscle Myosin IIA are Members of the Neural Precursor Cell Expressed Developmentally Down-Regulated 9 (NEDD9) Interactome in Head and Neck Squamous Cell Carcinoma Cells

Martina Semelakova, Stèphane Grauzam, Prabhakar Betadthunga, Jessica Tiedeken, Sonya Coaxum, David M. Neskey, Steven A. Rosenzweig

Transl Oncol. 2019 Jan; 12(1): 49–61. Published online 2018 Sep 26. doi: 10.1016/j.tranon.2018.09.006

PMCID:: PMC6160858

Abstract Article PDF–837K

Select item 611908717.

NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice

Rashid Gabbasov, Fang. Xiao, Caitlin G. Howe, Laura E. Bickel, Shane W. O’Brien, Daniel Benrubi, Thuy-Vy Do, Yan Zhou, Emmanuelle Nicolas, Kathy Q. Cai, Samuel Litwin, Sachiko Seo, Erica A. Golemis, Denise C. Connolly

Oncogene. Author manuscript; available in PMC 2018 Nov 18.

Published in final edited form as: Oncogene. 2018 Aug; 37(35): 4854–4870. Published online 2018 May 18. doi: 10.1038/s41388-018-0296-y

PMCID:: PMC6119087

Abstract Article PDF–1.3M

Select item 609715718.

Consortium-based genome-wide meta-analysis for childhood dental caries traits

Simon Haworth, Dmitry Shungin, Justin T van der Tas, Strahinja Vucic, Carolina Medina-Gomez, Victor Yakimov, Bjarke Feenstra, John R Shaffer, Myoung Keun Lee, Marie Standl, Elisabeth Thiering, Carol Wang, Klaus Bønnelykke, Johannes Waage, Leon Eyrich Jessen, Pia Elisabeth Nørrisgaard, Raimo Joro, Ilkka Seppälä, Olli Raitakari, Tom Dudding, Olja Grgic, Edwin Ongkosuwito, Anu Vierola, Aino-Maija Eloranta, Nicola X West, Steven J Thomas, Daniel W McNeil, Steven M Levy, Rebecca Slayton, Ellen A Nohr, Terho Lehtimäki, Timo Lakka, Hans Bisgaard, Craig Pennell, Jan Kühnisch, Mary L Marazita, Mads Melbye, Frank Geller, Fernando Rivadeneira, Eppo B Wolvius, Paul W Franks, Ingegerd Johansson, Nicholas J Timpson

Hum Mol Genet. 2018 Sep 1; 27(17): 3113–3127. Published online 2018 Jun 20. doi: 10.1093/hmg/ddy237

PMCID:: PMC6097157

Abstract Article PDF–794K

Select item 608755119.

Immunohistochemical expression of NEDD9, E-cadherin and γ-catenin and their prognostic significance in pancreatic ductal adenocarcinoma (PDAC)

Petra Radulović, Božo Krušlin

Bosn J Basic Med Sci. 2018 Aug; 18(3): 246–251. doi: 10.17305/bjbms.2018.2378

PMCID:: PMC6087551

Abstract Article PDF–1.0M

Select item 582692620.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

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