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Items: 1 to 20 of 33

1.
ATG4A regulates human erythroid maturation and mitochondrial clearance
Massiel Chavez Stolla, Andreea Reilly, Rochelle Bergantinos, Sintra Stewart, Neele Thom, Courtnee A. Clough, Rachel C. Wellington, Raisa Stolitenko, Janis L. Abkowitz, Sergei Doulatov
Blood Adv. 2022 Jun 28; 6(12): 3579–3589. Published online 2022 Jun 17. doi: 10.1182/bloodadvances.2021005910
PMCID:
PMC9631553
AbstractArticlePDF–1.6M
2.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
3.
Knockdown of ATG4A inhibits breast cancer progression and promotes tamoxifen chemosensitivity by suppressing autophagy
Qingfang Li, Lingling Zan
Mol Med Rep. 2022 Mar; 25(3): 101. Published online 2022 Jan 25. doi: 10.3892/mmr.2022.12617
PMCID:
PMC8822883
AbstractArticlePDF–3.8M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Mutations in LC3B2 and ATG4A underlie recurrent HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans
Alon Schneider Hait, David Olagnier, Vanessa Sancho-Shimizu, Kristian Alsbjerg Skipper, Marie Helleberg, Simon Muller Larsen, Chiranjeevi Bodda, Liviu Ionut Moldovan, Fanghui Ren, Nanna-Sophie Brinck-Andersen, Michelle M. Thomsen, Mette Ratzer Freytag, Sathya Darmalinggam, Isobel Parkes, Darshana D. Kadekar, Stine Hess Rahbek, Demi van der Horst, Lasse Sommer Kristensen, Kristina Eriksson, Jørgen Kjems, Serge Mostowy, Mette Christiansen, Jacob Giehm Mikkelsen, Christian Thomas Brandt, Søren R. Paludan, Trine H. Mogensen
Sci Immunol. Author manuscript; available in PMC 2021 Jun 23.
Published in final edited form as: Sci Immunol. 2020 Dec 11; 5(54): eabc2691. Published online 2020 Dec 11. doi: 10.1126/sciimmunol.abc2691
PMCID:
PMC7611067
AbstractArticlePDF–2.7M
6.
The insufficiency of ATG4A in macroautophagy
Nathan Nguyen, Taryn J. Olivas, Antonio Mires, Jiaxin Jin, Shenliang Yu, Lin Luan, Shanta Nag, Karlina J. Kauffman, Thomas J. Melia
J Biol Chem. 2020 Sep 25; 295(39): 13584–13600. Published online 2020 Jul 30. doi: 10.1074/jbc.RA120.013897
PMCID:
PMC7521654
AbstractArticlePDF–4.0M
7.
Overexpression of ATG4a promotes autophagy and proliferation, and inhibits apoptosis in lens epithelial cells via the AMPK and Akt pathways
Chufan Yan, Jiangyue Zhao, Yu Qin, Fangkun Zhao, Liyang Ji, Jinsong Zhang
Mol Med Rep. 2020 Aug; 22(2): 1295–1302. Published online 2020 Jun 2. doi: 10.3892/mmr.2020.11205
PMCID:
PMC7339427
AbstractArticlePDF–822K
8.
Long-noncoding RNA MALAT1 sponges microRNA-92a-3p to inhibit doxorubicin-induced cardiac senescence by targeting ATG4a
Wenzheng Xia, Hanbin Chen, Congying Xie, Meng Hou
Aging (Albany NY) 2020 May 15; 12(9): 8241–8260. Published online 2020 May 8. doi: 10.18632/aging.103136
PMCID:
PMC7244027
AbstractArticlePDF–2.4M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Human ATG4 autophagy proteases counteract attachment of ubiquitin-like LC3/GABARAP proteins to other cellular proteins
Alexander Agrotis, Lucas von Chamier, Harriet Oliver, Koshiro Kiso, Tanya Singh, Robin Ketteler
J Biol Chem. 2019 Aug 23; 294(34): 12610–12621. Published online 2019 Jul 17. doi: 10.1074/jbc.AC119.009977
PMCID:
PMC6709618
AbstractArticlePDF–2.8M
11.
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells
Alexander Agrotis, Niccolo Pengo, Jemima J. Burden, Robin Ketteler
Autophagy. 2019; 15(6): 976–997. Published online 2019 Feb 1. doi: 10.1080/15548627.2019.1569925
PMCID:
PMC6526816
AbstractArticlePDF–5.4M
12.
Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases
Karlina J. Kauffman, Shenliang Yu, Jiaxin Jin, Brian Mugo, Nathan Nguyen, Aidan O'Brien, Shanta Nag, Alf Håkon Lystad, Thomas J. Melia
Autophagy. 2018; 14(6): 992–1010. Published online 2018 Apr 10. doi: 10.1080/15548627.2018.1437341
PMCID:
PMC6103404
AbstractArticlePDF–2.2M
13.
Measurement of the Activity of the ATG4 Cysteine Proteases
Min Li, Yuanyuan Fu, Zuolong Yang, Xiao-Ming Yin
Methods Enzymol. Author manuscript; available in PMC 2017 Sep 4.
Published in final edited form as: Methods Enzymol. 2017; 587: 207–225. Published online 2016 Dec 5. doi: 10.1016/bs.mie.2016.10.024
PMCID:
PMC5582973
AbstractArticlePDF–793K
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8
Mads Skytte Rasmussen, Stéphane Mouilleron, Birendra Kumar Shrestha, Martina Wirth, Rebecca Lee, Kenneth Bowitz Larsen, Yakubu Abudu Princely, Nicola O'Reilly, Eva Sjøttem, Sharon A. Tooze, Trond Lamark, Terje Johansen
Autophagy. 2017; 13(5): 834–853. Published online 2017 Feb 15. doi: 10.1080/15548627.2017.1287651
PMCID:
PMC5446077
AbstractArticlePDF–1.9M
16.
ATG4A promotes tumor metastasis by inducing the epithelial-mesenchymal transition and stem-like properties in gastric cells
Shi-Wei Yang, Yi-Fang Ping, Yu-Xing Jiang, Xiao Luo, Xia Zhang, Xiu-Wu Bian, Pei-Wu Yu
Oncotarget. 2016 Jun 28; 7(26): 39279–39292. Published online 2016 Jun 4. doi: 10.18632/oncotarget.9827
PMCID:
PMC5129932
AbstractArticlePDF–2.8M
17.
An improved smaller biotin ligase for BioID proximity labeling
Dae In Kim, Samuel C. Jensen, Kyle A. Noble, Birendra KC, Kenneth H. Roux, Khatereh Motamedchaboki, Kyle J. Roux
Mol Biol Cell. 2016 Apr 15; 27(8): 1188–1196. doi: 10.1091/mbc.E15-12-0844
PMCID:
PMC4831873
AbstractArticlePDF–2.1M
18.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle
19.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
20.
Mir-24-3p downregulation contributes to VP16–DDP resistance in small-cell lung cancer by targeting ATG4A
Banzhou Pan, Yitian Chen, Haizhu Song, Yichen Xu, Rui Wang, Longbang Chen
Oncotarget. 2015 Jan; 6(1): 317–331. Published online 2014 Nov 16. doi: 10.18632/oncotarget.2787
PMCID:
PMC4381597
AbstractArticlePDF–7.6M

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