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Select item 108171281.

Association between ELMO1 gene polymorphisms and diabetic kidney disease: A systematic review and meta-analysis

Alireza Azarboo, Shaghayegh Hosseinkhani, Amirhossein Ghaseminejad-Raeini, Hossein Aazami, Sayed Mohammad Mohammadi, Saba Zeidi, Farideh Razi, Fatemeh Bandarian

PLoS One. 2024; 19(1): e0295607. Published online 2024 Jan 26. doi: 10.1371/journal.pone.0295607

PMCID:: PMC10817128

Abstract Article PDF–1.4M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 98996193.

Engulfment and cell motility protein 1 fosters reprogramming of tumor‐associated macrophages in colorectal cancer

Bo Wen, Sheng Li, Lei Ruan, Yanping Yang, Zilin Chen, Bin Zhang, Xin Yang, Haiqing Jie, Shujuan Li, Ziwei Zeng, Sisi Liu

Cancer Sci. 2023 Feb; 114(2): 410–422. Published online 2022 Dec 7. doi: 10.1111/cas.15628

PMCID:: PMC9899619

Abstract Article PDF–39M

Select item 84331494.

TNF-α-mediated m⁶A modification of ELMO1 triggers directional migration of mesenchymal stem cell in ankylosing spondylitis

Zhongyu Xie, Wenhui Yu, Guan Zheng, Jinteng Li, Shuizhong Cen, Guiwen Ye, Zhaofeng Li, Wenjie Liu, Ming Li, Jiajie Lin, Zepeng Su, Yunshu Che, Feng Ye, Peng Wang, Yanfeng Wu, Huiyong Shen

Nat Commun. 2021; 12: 5373. Published online 2021 Sep 10. doi: 10.1038/s41467-021-25710-4

PMCID:: PMC8433149

Abstract Article PDF–3.4M

Select item 82203915.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80849027.

ELMO1 and APOA1 as Candidate Genes for Sickle Cell Nephropathy

Santosh L. Saraf, Xu Zhang, Binal N. Shah, Rasha Raslan, Bamidele O. Tayo, James P. Lash, Nora Franceschini, Victor R. Gordeuk

Br J Haematol. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Br J Haematol. 2021 May; 193(3): 628–632. Published online 2020 Nov 20. doi: 10.1111/bjh.17224

PMCID:: PMC8084902

Abstract Article PDF–672K

Select item 80572588.

RhoG deficiency abrogates cytotoxicity of human lymphocytes and causes hemophagocytic lymphohistiocytosis

Artem Kalinichenko, Giovanna Perinetti Casoni, Loïc Dupré, Luca Trotta, Jakob Huemer, Donatella Galgano, Yolla German, Ben Haladik, Julia Pazmandi, Marini Thian, Özlem Yüce Petronczki, Samuel C. Chiang, Mervi Taskinen, Anne Hekkala, Saila Kauppila, Outi Lindgren, Terhi Tapiainen, Michael J. Kraakman, Kim Vettenranta, Alexis J. Lomakin, Janna Saarela, Mikko R. J. Seppänen, Yenan T. Bryceson, Kaan Boztug

Blood. 2021 Apr 15; 137(15): 2033–2045. Prepublished online 2021 Jan 29. doi: 10.1182/blood.2020008738

PMCID:: PMC8057258

Abstract Article

Select item 75892469.

The single nucleotide polymorphism rs11643718 in SLC12A3 is associated with the development of diabetic kidney disease in Chinese people with type 2 diabetes

J.‐F. Yang, X.‐F. Xiong, Y. Xiao, L. Wei, L. Li, M. Yang, Y.‐C. Han, H. Zhao, C.‐R. Li, N. Jiang, S. Xiong, L.‐F. Zeng, Z.‐G. Zhou, S.‐P. Liu, N.‐S. Wang, Y. Fan, L. Sun

Diabet Med. 2020 Nov; 37(11): 1879–1889. Published online 2020 Jul 23. doi: 10.1111/dme.14364

PMCID:: PMC7589246

Abstract Article PDF–1.7M

Select item 735199910.

Structure of the DOCK2−ELMO1 complex provides insights into regulation of the auto-inhibited state

Leifu Chang, Jing Yang, Chang Hwa Jo, Andreas Boland, Ziguo Zhang, Stephen H. McLaughlin, Afnan Abu-Thuraia, Ryan C. Killoran, Matthew J. Smith, Jean-Francois Côté, David Barford

Nat Commun. 2020; 11: 3464. Published online 2020 Jul 10. doi: 10.1038/s41467-020-17271-9

PMCID:: PMC7351999

Abstract Article PDF–5.8M

Select item 674264611.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 654263412.

ELMO1 variants and susceptibility to diabetic nephropathy in American Indians

Robert L. Hanson, Meredith P. Millis, Naomi J. Young, Sayuko Kobes, Robert G. Nelson, William C. Knowler, Johanna K. DiStefano

Mol Genet Metab. Author manuscript; available in PMC 2019 May 30.

Published in final edited form as: Mol Genet Metab. 2010 Dec; 101(4): 383–390. Published online 2010 Aug 19. doi: 10.1016/j.ymgme.2010.08.014

PMCID:: PMC6542634

Abstract Article PDF–794K

Select item 642409813.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

Select item 640282814.

A non-canonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis

Sanja Arandjelovic, Justin S.A. Perry, Christopher D. Lucas, Kristen K. Penberthy, Tae-Hyoun Kim, Ming Zhou, Dorian A Rosen, Tzu-Ying Chuang, Alexandra M. Bettina, Laura S. Shankman, Amanda H. Cohen, Alban Gaultier, Thomas P. Conrads, Minsoo Kim, Michael R. Elliott, Kodi S. Ravichandran

Nat Immunol. Author manuscript; available in PMC 2019 Jul 14.

Published in final edited form as: Nat Immunol. 2019 Feb; 20(2): 141–151. Published online 2019 Jan 14. doi: 10.1038/s41590-018-0293-x

PMCID:: PMC6402828

Abstract Article PDF–2.9M

Select item 633346015.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 607772216.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 596105017.

Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1

Wen Li, Ka Ming Vincent Tam, Wai Wa Ray Chan, Alex Chun Koon, Jacky Chi Ki Ngo, Ho Yin Edwin Chan, Kwok-Fai Lau

J Biol Chem. 2018 May 18; 293(20): 7674–7688. Published online 2018 Apr 3. doi: 10.1074/jbc.RA117.000505

PMCID:: PMC5961050

Abstract Article PDF–3.5M

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 464794119.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 464090220.

An Evolutionarily Conserved Autoinhibitory Molecular Switch in ELMO Proteins Regulates Rac Signaling

Manishha Patel, Yoran Margaron, Nadine Fradet, Qi Yang, Brian Wilkes, Michel Bouvier, Kay Hofmann, Jean-François Côté

Curr Biol. Author manuscript; available in PMC 2015 Nov 10.

Published in final edited form as: Curr Biol. 2010 Nov 23; 20(22): 2021–2027. Published online 2010 Oct 28. doi: 10.1016/j.cub.2010.10.028

PMCID:: PMC4640902

Abstract Article PDF–1.4M

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