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Select item 108740171.

The dynamic role of nucleoprotein SHCBP1 in the cancer cell cycle and its potential as a synergistic target for DNA-damaging agents in cancer therapy

Mei Zhou, Limin Duan, Jiangbin Chen, Yumei Li, Zhengrong Yin, Siwei Song, Yaqi Cao, Ping Luo, Fan Hu, Guanghai Yang, Juanjuan Xu, Tingting Liao, Yang Jin

Cell Commun Signal. 2024; 22: 131. Published online 2024 Feb 16. doi: 10.1186/s12964-024-01513-0

PMCID:: PMC10874017

Abstract Article PDF–23M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 92792854.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90588366.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 87486957.

EGF-induced nuclear translocation of SHCBP1 promotes bladder cancer progression through inhibiting RACGAP1-mediated RAC1 inactivation

Hubin Yin, Chen Zhang, Zongjie Wei, Weiyang He, Ning Xu, Yingjie Xu, Tinghao Li, Ke Ren, Youlin Kuang, Xin Zhu, Fangchao Yuan, Haitao Yu, Xin Gou

Cell Death Dis. 2022 Jan; 13(1): 39. Published online 2022 Jan 10. doi: 10.1038/s41419-021-04479-w

PMCID:: PMC8748695

Abstract Article PDF–8.3M

Select item 82784598.

Long Non-Coding RNA TP53TG1 Upregulates SHCBP1 to Promote Retinoblastoma Progression by Sponging miR-33b

Hongyi Wang, Zhen Zhang, Yue Zhang, Shihai Liu, Li Li

Cell Transplant. 2021 Jan-Dec; 30: 09636897211025223. Published online 2021 Jul 12. doi: 10.1177/09636897211025223

PMCID:: PMC8278459

Abstract Article PDF–2.3M

Select item 81799299.

The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase

Alexandra Daks, Alexey Petukhov, Olga Fedorova, Oleg Shuvalov, Alena Kizenko, Elizaveta Tananykina, Elena Vasileva, Oleg Semenov, Andrew Bottrill, Nickolai Barlev

Cell Death Dis. 2021 Jun; 12(6): 581. Published online 2021 Jun 5. doi: 10.1038/s41419-021-03871-w

PMCID:: PMC8179929

Abstract Article PDF–2.6M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 812185611.

Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer

Wengui Shi, Gengyuan Zhang, Zhijian Ma, Lianshun Li, Miaomiao Liu, Long Qin, Zeyuan Yu, Lei Zhao, Yang Liu, Xue Zhang, Junjie Qin, Huili Ye, Xiangyan Jiang, Huinian Zhou, Hui Sun, Zuoyi Jiao

Nat Commun. 2021; 12: 2812. Published online 2021 May 14. doi: 10.1038/s41467-021-23053-8

PMCID:: PMC8121856

Abstract Article PDF–4.5M

Select item 799391612.

SHCBP1 Promotes the Progression of Esophageal Squamous Cell Carcinoma Via the TGFβ Pathway

Chunhong Ren, Zhengbo Zhou, Xiuzhen Wang, Xu Hua, Muping Zou, Xin Zhang

Appl Immunohistochem Mol Morphol. 2021 Feb; 29(2): 136–143. Published online 2020 Aug 4. doi: 10.1097/PAI.0000000000000858

PMCID:: PMC7993916

Abstract Article PDF–506K

Select item 742732713.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 717491914.

PART1 and hsa-miR-429-Mediated SHCBP1 Expression Is an Independent Predictor of Poor Prognosis in Glioma Patients

Chengmin Xuan, Mingwei Jin, Lei Wang, Shengbai Xue, Qi An, Qingzeng Sun, Lei Wang, Yong Gao

Biomed Res Int. 2020; 2020: 1767056. Published online 2020 Apr 13. doi: 10.1155/2020/1767056

PMCID:: PMC7174919

Abstract Article PDF–1.5M

Select item 677813715.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 636571216.

SHCBP1 is a novel target and exhibits tumor-promoting effects in gastric cancer

Ya-Dong Dong, Yan-Li Yuan, Hai-Bo Yu, Guang-Jin Tian, De-Yu Li

Oncol Rep. 2019 Mar; 41(3): 1649–1657. Published online 2018 Dec 21. doi: 10.3892/or.2018.6952

PMCID:: PMC6365712

Abstract Article PDF–1.1M

Select item 635565117.

EGF-induced nuclear localization of SHCBP1 activates β-catenin signaling and promotes cancer progression

Lei Liu, Yi Yang, Shihua Liu, Tianyu Tao, Junchao Cai, Jueheng Wu, Hongyu Guan, Xun Zhu, Zhenjian He, Jun Li, Erwei Song, Musheng Zeng, Mengfeng Li

Oncogene. 2019; 38(5): 747–764. Published online 2018 Sep 3. doi: 10.1038/s41388-018-0473-z

PMCID:: PMC6355651

Abstract Article PDF–7.4M

Select item 589141718.

Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function

Jan B Heidelberger, Andrea Voigt, Marina E Borisova, Giuseppe Petrosino, Stefanie Ruf, Sebastian A Wagner, Petra Beli

EMBO Rep. 2018 Apr; 19(4): e44754. Published online 2018 Feb 21. doi: 10.15252/embr.201744754

PMCID:: PMC5891417

Abstract Article PDF–1.0M

Select item 586483219.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 572549420.

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair

Huiming Lu, Raghavendra A. Shamanna, Jessica K. de Freitas, Mustafa Okur, Prabhat Khadka, Tomasz Kulikowicz, Priscella P. Holland, Jane Tian, Deborah L. Croteau, Anthony J. Davis, Vilhelm A. Bohr

Nat Commun. 2017; 8: 2039. Published online 2017 Dec 11. doi: 10.1038/s41467-017-02146-3

PMCID:: PMC5725494

Abstract Article PDF–4.0M

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CCS copper chaperone for superoxide dismutase [Homo sapiens]
CCS copper chaperone for superoxide dismutase [Homo sapiens]
Gene ID:9973

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Rheumatoid arthritis and osteoarthritis: synovial fibroblasts
Rheumatoid arthritis and osteoarthritis: synovial fibroblasts
Accession: GDS2931

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