PMC Links for GEO Profiles (Select 124599886) - PMC

Select item 92626141.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67686403.

ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly

Dawn Hayward, Valentina L. Kouznetsova, Hannah E. Pierson, Nesrin M. Hasan, Estefany R. Guzman, Igor F. Tsigelny, Svetlana Lutsenko

J Biol Chem. 2019 Sep 27; 294(39): 14454–14466. Published online 2019 Jul 23. doi: 10.1074/jbc.RA119.008231

PMCID:: PMC6768640

Abstract Article PDF–3.6M

Select item 67194464.

BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress

Fei-Yun Chen, Min-Yu Huang, Yu-Min Lin, Chi-Huan Ho, Shu-Yu Lin, Hsin-Yi Chen, Mien-Chie Hung, Ruey-Hwa Chen

J Cell Biol. 2019 Sep 2; 218(9): 3002–3018. Published online 2019 Aug 6. doi: 10.1083/jcb.201901156

PMCID:: PMC6719446

Abstract Article PDF–3.9M

Select item 55784525.

Genome-Wide RNAi Ionomics Screen Reveals New Genes and Regulation of Human Trace Element Metabolism

Mikalai Malinouski, Nesrin M. Hasan, Yan Zhang, Javier Seravalli, Jie Lin, Andrei Avanesov, Svetlana Lutsenko, Vadim N. Gladyshev

Nat Commun. Author manuscript; available in PMC 2017 Aug 31.

Published in final edited form as: Nat Commun. 2014; 5: 3301. doi: 10.1038/ncomms4301

PMCID:: PMC5578452

Abstract Article PDF–2.4M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 46172117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 41245218.

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Dan E. Arking, Sara L. Pulit, Lia Crotti, Pim van der Harst, Patricia B. Munroe, Tamara T. Koopmann, Nona Sotoodehnia, Elizabeth J. Rossin, Michael Morley, Xinchen Wang, Andrew D. Johnson, Alicia Lundby, Daníel F. Gudbjartsson, Peter A. Noseworthy, Mark Eijgelsheim, Yuki Bradford, Kirill V. Tarasov, Marcus Dörr, Martina Müller-Nurasyid, Annukka M. Lahtinen, Ilja M. Nolte, Albert Vernon Smith, Joshua C. Bis, Aaron Isaacs, Stephen J. Newhouse, Daniel S. Evans, Wendy S. Post, Daryl Waggott, Leo-Pekka Lyytikäinen, Andrew A. Hicks, Lewin Eisele, David Ellinghaus, Caroline Hayward, Pau Navarro, Sheila Ulivi, Toshiko Tanaka, David J. Tester, Stéphanie Chatel, Stefan Gustafsson, Meena Kumari, Richard W. Morris, Åsa T. Naluai, Sandosh Padmanabhan, Alexander Kluttig, Bernhard Strohmer, Andrie G. Panayiotou, Maria Torres, Michael Knoflach, Jaroslav A. Hubacek, Kamil Slowikowski, Soumya Raychaudhuri, Runjun D. Kumar, Tamara B. Harris, Lenore J. Launer, Alan R. Shuldiner, Alvaro Alonso, Joel S. Bader, Georg Ehret, Hailiang Huang, W.H. Linda Kao, James B. Strait, Peter W. Macfarlane, Morris Brown, Mark J. Caulfield, Nilesh J. Samani, Florian Kronenberg, Johann Willeit, CARe Consortium, COGENT Consortium, J. Gustav Smith, Karin H. Greiser, Henriette Meyer zu Schwabedissen, Karl Werdan, Massimo Carella, Leopoldo Zelante, Susan R. Heckbert, Bruce M. Psaty, Jerome I. Rotter, Ivana Kolcic, Ozren Polašek, Alan F. Wright, Maura Griffin, Mark J. Daly, DCCT/EDIC, David O. Arnar, Hilma Hólm, Unnur Thorsteinsdottir, eMERGE consortium, Joshua C. Denny, Dan M. Roden, Rebecca L. Zuvich, Valur Emilsson, Andrew S. Plump, Martin G. Larson, Christopher J. O'Donnell, Xiaoyan Yin, Marco Bobbo, Adamo P. D'Adamo, Annamaria Iorio, Gianfranco Sinagra, Angel Carracedo, Steven R. Cummings, Michael A. Nalls, Antti Jula, Kimmo K. Kontula, Annukka Marjamaa, Lasse Oikarinen, Markus Perola, Kimmo Porthan, Raimund Erbel, Per Hoffmann, Karl-Heinz Jöckel, Hagen Kälsch, Markus M. Nöthen, HRGEN consortium, Marcel den Hoed, Ruth J.F. Loos, Dag S. Thelle, Christian Gieger, Thomas Meitinger, Siegfried Perz, Annette Peters, Hanna Prucha, Moritz F. Sinner, Melanie Waldenberger, Rudolf A. de Boer, Lude Franke, Pieter A. van der Vleuten, Britt Maria Beckmann, Eimo Martens, Abdennasser Bardai, Nynke Hofman, Arthur A.M. Wilde, Elijah R. Behr, Chrysoula Dalageorgou, John R. Giudicessi, Argelia Medeiros-Domingo, Julien Barc, Florence Kyndt, Vincent Probst, Alice Ghidoni, Roberto Insolia, Robert M. Hamilton, Stephen W. Scherer, Jeffrey Brandimarto, Kenneth Margulies, Christine E. Moravec, Greco M. Fabiola Del, Christian Fuchsberger, Jeffrey R. O'Connell, Wai K. Lee, Graham C.M. Watt, Harry Campbell, Sarah H. Wild, Nour E. El Mokhtari, Norbert Frey, Folkert W. Asselbergs, Irene Mateo Leach, Gerjan Navis, Maarten P. van den Berg, Dirk J. van Veldhuisen, Manolis Kellis, Bouwe P. Krijthe, Oscar H. Franco, Albert Hofman, Jan A. Kors, André G. Uitterlinden, Jacqueline C.M. Witteman, Lyudmyla Kedenko, Claudia Lamina, Ben A. Oostra, Gonçalo R. Abecasis, Edward G. Lakatta, Antonella Mulas, Marco Orrú, David Schlessinger, Manuela Uda, Marcello R.P. Markus, Uwe Völker, Harold Snieder, Timothy D. Spector, Johan Ärnlöv, Lars Lind, Johan Sundström, Ann-Christine Syvänen, Mika Kivimaki, Mika Kähönen, Nina Mononen, Olli T. Raitakari, Jorma S. Viikari, Vera Adamkova, Stefan Kiechl, Maria Brion, Andrew N. Nicolaides, Bernhard Paulweber, Johannes Haerting, Anna F. Dominiczak, Fredrik Nyberg, Peter H. Whincup, Aroon Hingorani, Jean-Jacques Schott, Connie R. Bezzina, Erik Ingelsson, Luigi Ferrucci, Paolo Gasparini, James F. Wilson, Igor Rudan, Andre Franke, Thomas W. Mühleisen, Peter P. Pramstaller, Terho J. Lehtimäki, Andrew D. Paterson, Afshin Parsa, Yongmei Liu, Cornelia van Duijn, David S. Siscovick, Vilmundur Gudnason, Yalda Jamshidi, Veikko Salomaa, Stephan B. Felix, Serena Sanna, Marylyn D. Ritchie, Bruno H. Stricker, Kari Stefansson, Laurie A. Boyer, Thomas P. Cappola, Jesper V. Olsen, Kasper Lage, Peter J. Schwartz, Stefan Kääb, Aravinda Chakravarti, Michael J. Ackerman, Arne Pfeufer, Paul I.W. de Bakker, Christopher Newton-Cheh

Nat Genet. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Nat Genet. 2014 Aug; 46(8): 826–836. Published online 2014 Jun 22. doi: 10.1038/ng.3014