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Select item 110313961.

Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1

Meng Wu, Weicheng Tang, Ying Chen, Liru Xue, Jun Dai, Yan Li, Xiaoran Zhu, Chuqing Wu, Jiaqiang Xiong, Jinjin Zhang, Tong Wu, Su Zhou, Dan Chen, Chaoyang Sun, Jing Yu, Hongyi Li, Yican Guo, Yibao Huang, Qingqing Zhu, Simin Wei, Ziliang Zhou, Mingfu Wu, Ya Li, Tao Xiang, Huiying Qiao, Shixuan Wang

Nat Aging. 2024; 4(4): 527–545. Published online 2024 Apr 9. doi: 10.1038/s43587-024-00607-1

PMCID:: PMC11031396

Abstract Article PDF–30M

Select item 110182052.

The role of transcription factor FOXA1/C2/M1/O3/P1/Q1 in breast cancer

Hui Yuan, Yu Liang, Shaorun Hu, Jinxiang Chen, Jingcan You, Jun Jiang, Mao Luo, Min Zeng

Medicine (Baltimore) 2024 Apr 12; 103(15): e37709. Published online 2024 Apr 12. doi: 10.1097/MD.0000000000037709

PMCID:: PMC11018205

Abstract Article PDF–3.3M

Select item 109332673.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 106462734.

NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer

Xiaona Chen, Yi Hao, Yong Liu, Sheng Zhong, Yuehua You, Keyi Ao, Tuotuo Chong, Xiaomin Luo, Minuo Yin, Ming Ye, Hui He, Anwei Lu, Jianjun Chen, Xin Li, Jian Zhang, Xia Guo

Adv Sci (Weinh) 2023 Nov; 10(32): 2302705. Published online 2023 Oct 11. doi: 10.1002/advs.202302705

PMCID:: PMC10646273

Abstract Article PDF–13M

Select item 104316665.

FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells

Seon Hye E. Park, Ashwinikumar Kulkarni, Genevieve Konopka

PLoS Biol. 2023 Aug; 21(8): e3001852. Published online 2023 Aug 4. doi: 10.1371/journal.pbio.3001852

PMCID:: PMC10431666

Abstract Article PDF–2.9M

Select item 103859796.

Deacetylation of FOXP1 by HDAC7 potentiates self-renewal of mesenchymal stem cells

Shifeng Ling, Tienan Chen, Shaojiao Wang, Wei Zhang, Rujiang Zhou, Xuechun Xia, Zhengju Yao, Ying Fan, Song Ning, Jiayin Liu, Lianju Qin, Haley O. Tucker, Niansong Wang, Xizhi Guo

Stem Cell Res Ther. 2023; 14: 188. Published online 2023 Jul 28. doi: 10.1186/s13287-023-03376-7

PMCID:: PMC10385979

Abstract Article PDF–6.8M

Select item 103581247.

Association of Double-Positive FOXA1 and FOXP1 Immunoreactivities with Favorable Prognosis of Tamoxifen-Treated Breast Cancer Patients

Nobuhiro Ijichi, Takashi Shigekawa, Kazuhiro Ikeda, Kuniko Horie-Inoue, Chikako Shimizu, Shigehira Saji, Kenjiro Aogi, Hitoshi Tsuda, Akihiko Osaki, Toshiaki Saeki, Satoshi Inoue

Horm Cancer. 2012 Aug; 3(4): 147–159. Published online 2012 Apr 3. doi: 10.1007/s12672-012-0111-0

PMCID:: PMC10358124

Abstract Article PDF–502K

Select item 103580508.

FOXP1, an Estrogen-Inducible Transcription Factor, Modulates Cell Proliferation in Breast Cancer Cells and 5-Year Recurrence-Free Survival of Patients with Tamoxifen-Treated Breast Cancer

Takashi Shigekawa, Nobuhiro Ijichi, Kazuhiro Ikeda, Kuniko Horie-Inoue, Chikako Shimizu, Shigehira Saji, Kenjiro Aogi, Hitoshi Tsuda, Akihiko Osaki, Toshiaki Saeki, Satoshi Inoue

Horm Cancer. 2011 Oct; 2(5): 286. Published online 2011 Sep 7. doi: 10.1007/s12672-011-0082-6

PMCID:: PMC10358050

Abstract Article PDF–490K

Select item 103522029.

miR-526b-5p/c-Myc/Foxp1 participates in recurrent spontaneous abortion by regulating the proliferation, migration, and invasion of trophoblasts

Li Luo, Lu Yao, Youlong Xie, Enxiang Chen, Yubin Ding, Luxing Ge

J Assist Reprod Genet. 2023 Jul; 40(7): 1559–1572. Published online 2023 Apr 13. doi: 10.1007/s10815-023-02793-0

PMCID:: PMC10352202

Abstract Article PDF–2.5M

Select item 1024470310.

The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes

Haixia Ma, Valentina Sukonina, Wei Zhang, Fang Meng, Santhilal Subhash, Henrik Palmgren, Ida Alexandersson, Huiming Han, Shuping Zhou, Stefano Bartesaghi, Chandrasekhar Kanduri, Sven Enerbäck

J Biol Chem. 2023 Jun; 299(6): 104795. Published online 2023 May 5. doi: 10.1016/j.jbc.2023.104795

PMCID:: PMC10244703

Abstract Article PDF–3.8M

Select item 1012096511.

Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging

Yiyuan Zhang, Yandong Zheng, Si Wang, Yanling Fan, Yanxia Ye, Yaobin Jing, Zunpeng Liu, Shanshan Yang, Muzhao Xiong, Kuan Yang, Jinghao Hu, Shanshan Che, Qun Chu, Moshi Song, Guang-Hui Liu, Weiqi Zhang, Shuai Ma, Jing Qu

Protein Cell. 2023 Apr; 14(4): 279–293. Published online 2022 Sep 6. doi: 10.1093/procel/pwac038

PMCID:: PMC10120965

Abstract Article PDF–11M

Select item 1003589912.

FOXP1 inhibits pancreatic cancer growth by transcriptionally regulating IRF1 expression

Le Wang, Ping Luo, Zhiwen Yang, Xiaoming Zhong, Changxue Ji

PLoS One. 2023; 18(3): e0280794. Published online 2023 Mar 23. doi: 10.1371/journal.pone.0280794

PMCID:: PMC10035899

Abstract Article PDF–2.6M

Select item 957694613.

Neglected, yet significant role of FOXP1 in T-cell quiescence, differentiation and exhaustion

Yaroslav Kaminskiy, Varvara Kuznetsova, Anna Kudriaeva, Ekaterina Zmievskaya, Emil Bulatov

Front Immunol. 2022; 13: 971045. Published online 2022 Oct 4. doi: 10.3389/fimmu.2022.971045

PMCID:: PMC9576946

Abstract Article PDF–860K

Select item 955498514.

The FoxP1 gene regulates lung function, production of matrix metalloproteinases and inflammatory mediators, and viability of lung epithelia

Alexis Andreas, Abby Maloy, Toru Nyunoya, Yingze Zhang, Divay Chandra

Respir Res. 2022; 23: 281. Published online 2022 Oct 11. doi: 10.1186/s12931-022-02213-4

PMCID:: PMC9554985

Abstract Article PDF–2.2M

Select item 939206315.

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li

Nat Commun. 2022; 13: 4906. Published online 2022 Aug 20. doi: 10.1038/s41467-022-32689-z

PMCID:: PMC9392063

Abstract Article PDF–2.0M

Select item 929024116.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Abstract Article PDF–8.2M

Select item 927928517.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 911973618.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983