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Items: 1 to 20 of 101

1.
A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification
Isabelle Plaisance, Panagiotis Chouvardas, Yuliangzi Sun, Mohamed Nemir, Parisa Aghagolzadeh, Farhang Aminfar, Sophie Shen, Woo Jun Shim, Francesca Rochais, Rory Johnson, Nathan Palpant, Thierry Pedrazzini
Cardiovasc Res. 2023 May; 119(6): 1361–1376. Published online 2022 Dec 20. doi: 10.1093/cvr/cvac191
PMCID:
PMC10262180
AbstractArticlePDF–2.1M
2.
BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL
Min Xia, Liron David, Matt Teater, Johana Gutierrez, Xiang Wang, Cem Meydan, Andrew Lytle, Graham W. Slack, David W. Scott, Ryan D. Morin, Ozlem Onder, Kojo S.J. Elenitoba-Johnson, Nahuel Zamponi, Leandro Cerchietti, Tianbao Lu, Ulrike Philippar, Lorena Fontan, Hao Wu, Ari M. Melnick
Cancer Discov. 2022 Aug 5; 12(8): 1922–1941. Published online 2022 Jun 3. doi: 10.1158/2159-8290.CD-21-1566
PMCID:
PMC9357155
AbstractArticlePDF–8.9M
3.
A nucleation barrier spring-loads the CBM signalosome for binary activation
Alejandro Rodriguez Gama, Tayla Miller, Jeffrey J Lange, Jay R Unruh, Randal Halfmann
eLife. 2022; 11: e79826. Published online 2022 Jun 21. doi: 10.7554/eLife.79826
PMCID:
PMC9342958
AbstractArticlePDF–7.3M
4.
A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells
Hongli Yin, Ozge Karayel, Ying-Yin Chao, Thomas Seeholzer, Isabel Hamp, Oliver Plettenburg, Torben Gehring, Christina Zielinski, Matthias Mann, Daniel Krappmann
Cell Mol Life Sci. 2022 Feb; 79(2): 112. Published online 2022 Jan 31. doi: 10.1007/s00018-022-04154-z
PMCID:
PMC8803816
AbstractArticlePDF–9.2M
5.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
6.
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation
Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang
Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5
PMCID:
PMC8314547
AbstractArticlePDF–3.7M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO
Zhou Yu, Xuelian Li, Mingjin Yang, Jiaying Huang, Qian Fang, Jianjun Jia, Zheng Li, Yan Gu, Taoyong Chen, Xuetao Cao
Signal Transduct Target Ther. 2021; 6: 90. Published online 2021 Feb 28. doi: 10.1038/s41392-021-00477-8
PMCID:
PMC7914255
AbstractArticlePDF–4.7M
9.
Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-κB Activation Pathway
Daisuke Oikawa, Naoya Hatanaka, Takashi Suzuki, Fuminori Tokunaga
Front Immunol. 2020; 11: 601926. Published online 2020 Nov 23. doi: 10.3389/fimmu.2020.601926
PMCID:
PMC7732508
AbstractArticlePDF–8.4M
10.
Correlation analysis between CARMEN variants and alcohol-induced osteonecrosis of the femoral head in the Chinese population
Yongchang Guo, Yuju Cao, Shunguo Gong, Sumei Zhang, Fengzhi Hou, Xinjie Zhang, Jiangeng Hu, Zhimin Yang, Juanjuan Yi, Dan Luo, Xifeng Chen, Jingbo Song
BMC Musculoskelet Disord. 2020; 21: 547. Published online 2020 Aug 15. doi: 10.1186/s12891-020-03553-2
PMCID:
PMC7429464
AbstractArticlePDF–621K
11.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
12.
GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein
Jing Cheng, Linda R. Klei, Nathaniel E. Hubel, Ming Zhang, Rebekka Schairer, Lisa M. Maurer, Hanna B. Klei, Heejae Kang, Vincent J. Concel, Phillip C. Delekta, Eric V. Dang, Michelle A. Mintz, Mathijs Baens, Jason G. Cyster, Narayanan Parameswaran, Margot Thome, Peter C. Lucas, Linda M. McAllister-Lucas
J Clin Invest. 2020 Feb 3; 130(2): 1036–1051. Published online 2020 Jan 21. doi: 10.1172/JCI97040
PMCID:
PMC6994119
AbstractArticlePDF–8.3M
13.
Paracaspase MALT1 regulates glioma cell survival by controlling endo‐lysosome homeostasis
Kathryn A Jacobs, Gwennan André‐Grégoire, Clément Maghe, An Thys, Ying Li, Elizabeth Harford‐Wright, Kilian Trillet, Tiphaine Douanne, Carolina Alves Nicolau, Jean‐Sébastien Frénel, Nicolas Bidère, Julie Gavard
EMBO J. 2020 Jan 2; 39(1): e102030. Published online 2019 Nov 27. doi: 10.15252/embj.2019102030
PMCID:
PMC6939194
AbstractArticlePDF–3.8M
14.
Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling
Zhaoquan Wang, Shelby M. Hutcherson, Chao Yang, Rakhi P. Jattani, Julia M. Tritapoe, Yong-Kang Yang, Joel L. Pomerantz
J Biol Chem. 2019 Oct 4; 294(40): 14648–14660. Published online 2019 Aug 7. doi: 10.1074/jbc.RA119.009551
PMCID:
PMC6779434
AbstractArticlePDF–3.3M
15.
Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners
Eunate Gallardo-Vara, Lidia Ruiz-Llorente, Juan Casado-Vela, María J. Ruiz-Rodríguez, Natalia López-Andrés, Asit K. Pattnaik, Miguel Quintanilla, Carmelo Bernabeu
Cells. 2019 Sep; 8(9): 1082. Published online 2019 Sep 13. doi: 10.3390/cells8091082
PMCID:
PMC6769930
AbstractArticlePDF–4.3M
16.
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation
Michael J. Holliday, Axel Witt, Alejandro Rodríguez Gama, Benjamin T. Walters, Christopher P. Arthur, Randal Halfmann, Alexis Rohou, Erin C. Dueber, Wayne J. Fairbrother
Nat Commun. 2019; 10: 3070. Published online 2019 Jul 11. doi: 10.1038/s41467-019-10953-z
PMCID:
PMC6624267
AbstractArticlePDF–5.4M
17.
The CARMA3-Bcl10-MALT1 Signalosome Drives NF-κB Activation and Promotes Aggressiveness in Angiotensin II Receptor-positive Breast Cancer.
Prasanna Ekambaram, Jia-Ying (Lloyd) Lee, Nathaniel E. Hubel, Dong Hu, Saigopalakrishna Yerneni, Phil G. Campbell, Netanya Pollock, Linda R. Klei, Vincent J. Concel, Phillip C. Delekta, Arul M. Chinnaiyan, Scott A. Tomlins, Daniel R. Rhodes, Nolan Priedigkeit, Adrian V. Lee, Steffi Oesterreich, Linda M. McAllister-Lucas, Peter C. Lucas
Cancer Res. Author manuscript; available in PMC 2019 Mar 27.
Published in final edited form as: Cancer Res. 2018 Mar 1; 78(5): 1225–1240. Published online 2017 Dec 19. doi: 10.1158/0008-5472.CAN-17-1089
PMCID:
PMC6436094
AbstractArticlePDF–2.4M
18.
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9
Michael J. Holliday, Ryan Ferrao, Gladys de Leon Boenig, Alberto Estevez, Elizabeth Helgason, Alexis Rohou, Erin C. Dueber, Wayne J. Fairbrother
J Biol Chem. 2018 Oct 26; 293(43): 16803–16817. Published online 2018 Sep 11. doi: 10.1074/jbc.RA118.004821
PMCID:
PMC6204897
AbstractArticlePDF–3.1M
19.
Molecular architecture and regulation of BCL10-MALT1 filaments
Florian Schlauderer, Thomas Seeholzer, Ambroise Desfosses, Torben Gehring, Mike Strauss, Karl-Peter Hopfner, Irina Gutsche, Daniel Krappmann, Katja Lammens
Nat Commun. 2018; 9: 4041. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06573-8
PMCID:
PMC6168461
AbstractArticlePDF–3.7M
20.
The CBM-opathies—A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 Complex
Henry Y. Lu, Bradly M. Bauman, Swadhinya Arjunaraja, Batsukh Dorjbal, Joshua D. Milner, Andrew L. Snow, Stuart E. Turvey
Front Immunol. 2018; 9: 2078. Published online 2018 Sep 19. doi: 10.3389/fimmu.2018.02078
PMCID:
PMC6156466
AbstractArticlePDF–1.8M

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