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Items: 1 to 20 of 96

1.
WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8
Lei Zhou, Yun Zhong, Fan Wang, Yi Guo, Rui Mao, Hongfu Xie, Yiya Zhang, Ji Li
Int J Biol Sci. 2024; 20(5): 1763–1777. Published online 2024 Feb 25. doi: 10.7150/ijbs.90459
PMCID:
PMC10929181
AbstractArticlePDF–6.5M
2.
IRF8 as a Novel Marker to Differentiate Between CD30-Positive Large Cell Lymphomas
Daniel C McQuaid, Samuel G Katz, Mina L Xu
Am J Clin Pathol. 2022 Aug; 158(2): 173–176. Published online 2022 Apr 23. doi: 10.1093/ajcp/aqac044
Correction in:
Am J Clin Pathol. 2024 Jan; 161(1): 107.
PMCID:
PMC10664184
AbstractArticlePDF–4.6M
3.
Global assessment of IRF8 as a novel cancer biomarker
Daniel C. McQuaid, Gauri Panse, Wei-Lien Wang, Geraldine S. Pinkus, Samuel G. Katz, Mina L. Xu
Hum Pathol. Author manuscript; available in PMC 2023 Nov 2.
Published in final edited form as: Hum Pathol. 2022 Apr; 122: 1–10. Published online 2022 Jan 24. doi: 10.1016/j.humpath.2022.01.004
PMCID:
PMC10621657
AbstractArticlePDF–2.2M
4.
Expression of Interferon Regulatory Factor 8 (IRF8) and Its Association with Infections in Dialysis Patients
Justa Friebus-Kardash, Fei Kuang, Tobias Peitz, Thamer A. Hamdan, Ute Eisenberger, Kristina Boss, Andreas Kribben, Karl Sebastian Lang, Michael Jahn
Cells. 2023 Jul; 12(14): 1892. Published online 2023 Jul 19. doi: 10.3390/cells12141892
PMCID:
PMC10378315
AbstractArticlePDF–1.8M
5.
IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes
Dakota B. Poschel, Mercy Kehinde-Ige, John D. Klement, Dafeng Yang, Alyssa D. Merting, Natasha M. Savage, Huidong Shi, Kebin Liu
Cells. 2023 Jan; 12(2): 310. Published online 2023 Jan 13. doi: 10.3390/cells12020310
PMCID:
PMC9856547
AbstractArticlePDF–3.8M
6.
Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer
Briana G. Nixon, Fengshen Kuo, LiangLiang Ji, Ming Liu, Kristelle Capistrano, Mytrang Do, Ruth A. Franklin, Xiaodi Wu, Emily R. Kansler, Raghvendra M. Srivastava, Tanaya A. Purohit, Alejandro Sanchez, Lynda Vuong, Chirag Krishna, Xinxin Wang, Herbert C. Morse, III, James J. Hsieh, Timothy A. Chan, Kenneth M. Murphy, James J. Moon, A. Ari Hakimi, Ming O. Li
Immunity. Author manuscript; available in PMC 2023 Nov 8.
Published in final edited form as: Immunity. 2022 Nov 8; 55(11): 2044–2058.e5. Published online 2022 Oct 25. doi: 10.1016/j.immuni.2022.10.002
PMCID:
PMC9649891
AbstractArticlePDF–3.4M
7.
Loss of a negative feedback loop between IRF8 and AR promotes prostate cancer growth and enzalutamide resistance
Hongxi Wu, Linjun You, Yan Li, Zhili Zhao, Guangjiang Shi, Zhen Chen, Zhuo Wang, Xianjing Li, Shijia Du, Wanli Ye, Xiaofang Gao, Jingjing Duan, Yan Cheng, Weiyan Tao, Jinsong Bian, Jin-Rong Zhou, Qingyi Zhu, Yong Yang
Cancer Res. Author manuscript; available in PMC 2022 Oct 26.
Published in final edited form as: Cancer Res. 2020 Jul 1; 80(13): 2927–2939. Published online 2020 Apr 27. doi: 10.1158/0008-5472.CAN-19-2549
PMCID:
PMC9601976
AbstractArticlePDF–3.4M
8.
Expression of the Interferon Regulatory Factor 8/ICSBP-1 in Human Reactive Lymphoid Tissues and B-cell Lymphomas: A Novel Germinal Center Marker
Antonio Martinez, Stefania Pittaluga, Martina Rudelius, Theresa Davies-Hill, Denise Sebasigari, Thomas J. Fountaine, Stephen Hewitt, Elaine S. Jaffe, Mark Raffeld
Am J Surg Pathol. Author manuscript; available in PMC 2022 Apr 25.
Published in final edited form as: Am J Surg Pathol. 2008 Aug; 32(8): 1190–1200. doi: 10.1097/PAS.0b013e318166f46a
PMCID:
PMC9036392
AbstractArticlePDF–4.1M
9.
IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma
Suraya Elfrink, Martin ter Beest, Luuk Janssen, Marijke P. Baltissen, Pascal W. T. C. Jansen, Angelique N. Kenyon, Raymond M. Steen, Daynelys de Windt, Philipp M. Hagemann, Corine Hess, Dick-Johan van Spronsen, Brigiet Hoevenaars, Ellen van der Spek, Zijun Y. Xu-Monette, Ken H. Young, Charlotte Kaffa, Sander Bervoets, Jolien van Heek, Eva Hesius, Charlotte M. de Winde, Michiel Vermeulen, Michiel van den Brand, Blanca Scheijen, Annemiek B. van Spriel
Blood Adv. 2022 Apr 12; 6(7): 2254–2266. Published online 2022 Apr 4. doi: 10.1182/bloodadvances.2021004366
PMCID:
PMC9006271
AbstractArticlePDF–1.6M
10.
Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery
Tian Zhou, Xinyi Zhu, Zhizhong Ye, Yong-Fei Wang, Chao Yao, Ning Xu, Mi Zhou, Jianyang Ma, Yuting Qin, Yiwei Shen, Yuanjia Tang, Zhihua Yin, Hong Xu, Yutong Zhang, Xiaoli Zang, Huihua Ding, Wanling Yang, Ya Guo, John B. Harley, Bahram Namjou, Kenneth M. Kaufman, Leah C. Kottyan, Matthew T. Weirauch, Guojun Hou, Nan Shen
Nat Commun. 2022; 13: 1855. Published online 2022 Apr 6. doi: 10.1038/s41467-022-29514-y
PMCID:
PMC8987079
AbstractArticlePDF–2.1M
11.
ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
Zhendong Cao, Krista A. Budinich, Hua Huang, Diqiu Ren, Bin Lu, Zhen Zhang, Qingzhou Chen, Yeqiao Zhou, Yu-Han Huang, Fatemeh Alikarami, Molly C. Kingsley, Alexandra K. Lenard, Aoi Wakabayashi, Eugene Khandros, Will Bailis, Jun Qi, Martin P. Carroll, Gerd A. Blobel, Robert B. Faryabi, Kathrin M. Bernt, Shelley L. Berger, Junwei Shi
Mol Cell. Author manuscript; available in PMC 2022 Mar 18.
Published in final edited form as: Mol Cell. 2021 Sep 2; 81(17): 3604–3622.e10. Published online 2021 Aug 5. doi: 10.1016/j.molcel.2021.07.018
PMCID:
PMC8932643
AbstractArticlePDF–3.3M
12.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
13.
Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP
Honglin Wang, Pujan Joshi, Seung-Hyun Hong, Peter F. Maye, David W. Rowe, Dong-Guk Shin
BMC Genomics. 2022; 23: 14. Published online 2022 Jan 7. doi: 10.1186/s12864-021-08159-z
PMCID:
PMC8740472
AbstractArticlePDF–2.0M
14.
Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype
Ruben A.L. de Groen, Ronald van Eijk, Stefan Böhringer, Tom van Wezel, Richard Raghoo, Dina Ruano, Patty M. Jansen, Inge Briaire-de Bruijn, Fleur A. de Groot, Karin Kleiverda, Liane te Boome, Valeska Terpstra, Henriette Levenga, Alina Nicolae, Eduardus F.M. Posthuma, Isabelle Focke-Snieders, Lizan Hardi, Wietske C.E. den Hartog, Lara H. Bohmer, Pancras C.W. Hogendoorn, Anke van den Berg, Arjan Diepstra, Marcel Nijland, Pieternella J. Lugtenburg, Marie José Kersten, Steven T. Pals, Hendrik Veelken, Judith V.M.G. Bovée, Arjen H.G. Cleven, Joost S.P. Vermaat
Blood Adv. 2021 Oct 12; 5(19): 3760–3775. Prepublished online 2021 Sep 3. Published online 2021 Oct 1. doi: 10.1182/bloodadvances.2021005215
PMCID:
PMC8679674
AbstractArticlePDF–3.1M
15.
Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis
Aaron Ions Gardner, Yuqing Wu, Rabea Verhaegh, Yongjie Liu, Barbara Wilker, Matthias Soddemann, Simone Keitsch, Michael J. Edwards, Iram J. Haq, Markus Kamler, Katrin Anne Becker, Malcolm Brodlie, Erich Gulbins
J Biol Chem. 2021 Jan-Jun; 296: 100650. Published online 2021 Apr 9. doi: 10.1016/j.jbc.2021.100650
PMCID:
PMC8113888
AbstractArticlePDF–2.0M
16.
Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients
Carole Le Coz, David N. Nguyen, Chun Su, Brian E. Nolan, Amanda V. Albrecht, Suela Xhani, Di Sun, Benjamin Demaree, Piyush Pillarisetti, Caroline Khanna, Francis Wright, Peixin Amy Chen, Samuel Yoon, Amy L. Stiegler, Kelly Maurer, James P. Garifallou, Amy Rymaszewski, Steven H. Kroft, Timothy S. Olson, Alix E. Seif, Gerald Wertheim, Struan F.A. Grant, Linda T. Vo, Jennifer M. Puck, Kathleen E. Sullivan, John M. Routes, Viktoria Zakharova, Anna Shcherbina, Anna Mukhina, Natasha L. Rudy, Anna C.E. Hurst, T. Prescott Atkinson, Titus J. Boggon, Hakon Hakonarson, Adam R. Abate, Joud Hajjar, Sarah K. Nicholas, James R. Lupski, James Verbsky, Ivan K. Chinn, Michael V. Gonzalez, Andrew D. Wells, Alex Marson, Gregory M.K. Poon, Neil Romberg
J Exp Med. 2021 Jul 5; 218(7): e20201750. Published online 2021 May 5. doi: 10.1084/jem.20201750
PMCID:
PMC8105723
AbstractArticlePDF–5.9M
17.
PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome via Regulating Its Expression in Human Macrophages
Takuya Yashiro, Machiko Yamamoto, Sanae Araumi, Mutsuko Hara, Kyoko Yogo, Koichiro Uchida, Kazumi Kasakura, Chiharu Nishiyama
Front Immunol. 2021; 12: 649572. Published online 2021 Apr 7. doi: 10.3389/fimmu.2021.649572
PMCID:
PMC8058198
AbstractArticlePDF–1.9M
18.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
19.
High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer
Gerardo Gatti, Courtney Betts, Darío Rocha, Maribel Nicola, Verónica Grupe, Cecilia Ditada, Nicolas G. Nuñez, Emiliano Roselli, Paula Araya, Jeremías Dutto, Lucia Boffelli, Elmer Fernández, Lisa M. Coussens, Mariana Maccioni
Breast Cancer Res. 2021; 23: 40. Published online 2021 Mar 25. doi: 10.1186/s13058-021-01418-7
Correction in:
Breast Cancer Res. 2021; 23: 48.
PMCID:
PMC7992828
AbstractArticlePDF–6.2M
20.
Circulating IRF8-expressing CD123+CD127+ lymphoid progenitors: key players in human hematopoiesis
Kai Ling Liang, Elisa Laurenti, Tom Taghon
Trends Immunol. Author manuscript; available in PMC 2023 Sep 1.
Published in final edited form as: Trends Immunol. 2023 Aug 15; 44(9): 678–692. Published online 2023 Aug 15. doi: 10.1016/j.it.2023.07.004
PMCID:
PMC7614993
AbstractArticlePDF–1.8M

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