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Select item 96973431.

PAC₁, VPAC₁, and VPAC₂ Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies

Zoe Tasma, Andrew Siow, Paul W. R. Harris, Margaret A. Brimble, Simon J. O’Carroll, Debbie L. Hay, Christopher S. Walker

Int J Mol Sci. 2022 Nov; 23(22): 13797. Published online 2022 Nov 9. doi: 10.3390/ijms232213797

PMCID:: PMC9697343

Abstract Article PDF–15M

Select item 93088752.

VIPR1启动子甲基化促进转录因子AP-2α下调VIPR1的表达并促进肝细胞癌的生长

宁诗雨, 何春梅, 郭泽皓, 张豪, 莫之婧

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Jul 20; 42(7): 957–965. Chinese. doi: 10.12122/j.issn.1673-4254.2022.07.01

PMCID:: PMC9308875

Abstract Article PDF–2.1M

Select item 92950673.

Activation of VIPR1 suppresses hepatocellular carcinoma progression by regulating arginine and pyrimidine metabolism

Yaojie Fu, Shanshan Liu, Robim M. Rodrigues, Ying Han, Cao Guo, Zhanwei Zhu, Yong He, Bryan Mackowiak, Dechun Feng, Bin Gao, Shan Zeng, Hong Shen

Int J Biol Sci. 2022; 18(11): 4341–4356. Published online 2022 Jul 4. doi: 10.7150/ijbs.71134

PMCID:: PMC9295067

Abstract Article PDF–4.3M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74315775.

Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy

Jia Duan, Dan-dan Shen, X. Edward Zhou, Peng Bi, Qiu-feng Liu, Yang-xia Tan, You-wen Zhuang, Hui-bing Zhang, Pei-yu Xu, Si-Jie Huang, Shan-shan Ma, Xin-heng He, Karsten Melcher, Yan Zhang, H. Eric Xu, Yi Jiang

Nat Commun. 2020; 11: 4121. Published online 2020 Aug 17. doi: 10.1038/s41467-020-17933-8

PMCID:: PMC7431577

Abstract Article PDF–2.3M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67978687.

Immune evasion by Salmonella: exploiting the VPAC1/VIP axis in human monocytes

Basim Askar, John Higgins, Paul Barrow, Neil Foster

Immunology. 2019 Nov; 158(3): 230–239. Published online 2019 Sep 11. doi: 10.1111/imm.13107

PMCID:: PMC6797868

Abstract Article PDF–1.4M

Select item 65175808.

Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients

R. Villanueva-Romero, I. Gutiérrez-Cañas, M. Carrión, I. González-Álvaro, J. M. Rodríguez-Frade, M. Mellado, C. Martínez, R. P. Gomariz, Y. Juarranz

Sci Rep. 2019; 9: 7383. Published online 2019 May 14. doi: 10.1038/s41598-019-43717-2

PMCID:: PMC6517580

Abstract Article PDF–4.6M

Select item 56785819.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549522511.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 541963412.

The Vasoactive Intestinal Peptide (VIP) α-Helix Up to C Terminus Interacts with the N-Terminal Ectodomain of the Human VIP/Pituitary Adenylate Cyclase-Activating Peptide 1 Receptor: Photoaffinity, Molecular Modeling, and Dynamics

Emilie Ceraudo, Samuel Murail, Yossan-Var Tan, Jean-Jacques Lacapère, Jean-Michel Neumann, Alain Couvineau, Marc Laburthe

Mol Endocrinol. January 1, 2008; 22(1): 147–155. doi: 10.1210/me.2007-0361

PMCID:: PMC5419634

Abstract Article

Select item 475555813.

Clinical Relevance of VPAC1 Receptor Expression in Early Arthritis: Association with IL-6 and Disease Activity

Iria V. Seoane, Ana M. Ortiz, Lorena Piris, Amalia Lamana, Yasmina Juarranz, Rosario García-Vicuña, Isidoro González-Álvaro, Rosa P. Gomariz, Carmen Martínez

PLoS One. 2016; 11(2): e0149141. Published online 2016 Feb 16. doi: 10.1371/journal.pone.0149141

PMCID:: PMC4755558

Abstract Article PDF–1.1M

Select item 422924014.

Single Nucleotide Polymorphisms in the 3′UTR of VPAC-1 Cooperate in Modulating Gene Expression and Impact Differently on the Interaction with miR525-5p

Fabiana Paladini, Nicla Porciello, Giorgio Camilli, Sinem Tuncer, Elisa Cocco, Maria Teresa Fiorillo, Rosa Sorrentino

PLoS One. 2014; 9(11): e112646. Published online 2014 Nov 12. doi: 10.1371/journal.pone.0112646

PMCID:: PMC4229240

Abstract Article PDF–441K

Select item 412433215.

Expression of pituitary adenylate cyclase-activating polypeptide 1 and 2 receptor mRNA in gallbladder tissue of patients with gallstone or gallbladder polyps

Zhen-Hai Zhang, Shuo-Dong Wu, Hong Gao, Gang Shi, Jun-Zhe Jin, Jing Kong, Zhong Tian, Yang Su

World J Gastroenterol. 2006 Mar 7; 12(9): 1468–1471. Published online 2006 Mar 7. doi: 10.3748/wjg.v12.i9.1468

PMCID:: PMC4124332

Abstract Article PDF–706K

Select item 374693216.

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

Tory P. Johnson, Karan Patel, Kory R. Johnson, Dragan Maric, Peter A. Calabresi, Rodrigo Hasbun, Avindra Nath

Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33): 13588–13593. Published online 2013 Jul 29. doi: 10.1073/pnas.1308673110

PMCID:: PMC3746932

Abstract Article PDF–1002K

Select item 365140117.

VPAC1 receptor expression in peripheral blood mononuclear cells in a human endotoxemia model

Angela Storka, Bernhard Burian, Gerhard Führlinger, Breanna Clive, Terri Sun, Richard Crevenna, Andrea Gsur, Wilhelm Mosgöller, Michael Wolzt

J Transl Med. 2013; 11: 117. Published online 2013 May 7. doi: 10.1186/1479-5876-11-117

PMCID:: PMC3651401

Abstract Article PDF–247K

Select item 358195418.

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins

Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110

PMCID:: PMC3581954

Abstract Article PDF–2.3M

Select item 326170819.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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