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Select item 102644841.

Thermodynamic Evolution of a Metamorphic Protein: A Theoretical-Computational Study of Human Lymphotactin

Laura Zanetti-Polzi, Isabella Daidone, Claudio Iacobucci, Andrea Amadei

Protein J. 2023; 42(3): 219–228. Published online 2023 May 26. doi: 10.1007/s10930-023-10123-7

PMCID:: PMC10264484

Abstract Article PDF–1.8M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80175593.

Evolution of Fold-Switching in a Metamorphic Protein

Acacia F. Dishman, Robert C. Tyler, Jamie C. Fox, Andrew B. Kleist, Kenneth E. Prehoda, M. Madan Babu, Francis C. Peterson, Brian F. Volkman

Science. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Science. 2021 Jan 1; 371(6524): 86–90. doi: 10.1126/science.abd8700

PMCID:: PMC8017559

Abstract Article PDF–1.1M

Select item 80045334.

Specific binding-induced modulation of the XCL1 metamorphic equilibrium

Acacia F. Dishman, Francis C. Peterson, Brian F. Volkman

Biopolymers. Author manuscript; available in PMC 2021 Oct 26.

Published in final edited form as: Biopolymers. 2021 Oct; 112(10): e23402. Published online 2020 Sep 28. doi: 10.1002/bip.23402

PMCID:: PMC8004533

Abstract Article PDF–1.0M

Select item 77962965.

Involvement of the ERK/HIF-1α/EMT Pathway in XCL1-Induced Migration of MDA-MB-231 and SK-BR-3 Breast Cancer Cells

Ha Thi Thu Do, Jungsook Cho

Int J Mol Sci. 2021 Jan; 22(1): 89. Published online 2020 Dec 23. doi: 10.3390/ijms22010089

PMCID:: PMC7796296

Abstract Article PDF–5.9M

Select item 71765846.

XCL1 expression correlates with CD8-positive T cells infiltration and PD-L1 expression in squamous cell carcinoma arising from mature cystic teratoma of the ovary

Ryo Tamura, Kosuke Yoshihara, Hirofumi Nakaoka, Nozomi Yachida, Manako Yamaguchi, Kazuaki Suda, Tatsuya Ishiguro, Koji Nishino, Hiroshi Ichikawa, Keiichi Homma, Akira Kikuchi, Yutaka Ueda, Yuji Takei, Hiroyuki Fujiwara, Teiichi Motoyama, Shujiro Okuda, Toshifumi Wakai, Ituro Inoue, Takayuki Enomoto

Oncogene. 2020; 39(17): 3541–3554. Published online 2020 Mar 2. doi: 10.1038/s41388-020-1237-0

PMCID:: PMC7176584

Abstract Article PDF–1.7M

Select item 70601167.

DIEPOXYBUTANE INDUCES THE EXPRESSION OF A NOVEL p53-TARGET GENE XCL1 THAT MEDIATES APOPTOSIS IN EXPOSED HUMAN LYMPHOBLASTS.

Akamu J. Ewunkem, Maya Deve, Scott H. Harrison, Perpetua M. Muganda

J Biochem Mol Toxicol. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: J Biochem Mol Toxicol. 2020 Mar; 34(3): e22446. Published online 2020 Jan 18. doi: 10.1002/jbt.22446

PMCID:: PMC7060116

Abstract Article PDF–1.1M

Select item 67337568.

Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1

Jamie C. Fox, Monica A. Thomas, Acacia F. Dishman, Olav Larsen, Takashi Nakayama, Osamu Yoshie, Mette Marie Rosenkilde, Brian F. Volkman

Sci Signal. Author manuscript; available in PMC 2020 Mar 3.

Published in final edited form as: Sci Signal. 2019 Sep 3; 12(597): eaat4128. Published online 2019 Sep 3. doi: 10.1126/scisignal.aat4128

PMCID:: PMC6733756

Abstract Article PDF–2.4M

Select item 66941449.

The systemic exercise-released chemokine lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation

Odette Leiter, Stefanie N. Bernas, Suse Seidemann, Rupert W. Overall, Cindy Horenburg, Susann Kowal, Gerd Kempermann, Tara L. Walker

Sci Rep. 2019; 9: 11831. Published online 2019 Aug 14. doi: 10.1038/s41598-019-48360-5

PMCID:: PMC6694144

Abstract Article PDF–1.7M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 477528611.

Examination of Glycosaminoglycan Binding Sites on the XCL1 Dimer

Jamie C. Fox, Robert C. Tyler, Francis C. Peterson, Douglas P. Dyer, Fuming Zhang, Robert J. Linhardt, Tracy M. Handel, Brian F. Volkman

Biochemistry. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Biochemistry. 2016 Mar 1; 55(8): 1214–1225. Published online 2016 Feb 17. doi: 10.1021/acs.biochem.5b01329

PMCID:: PMC4775286

Abstract Article PDF–1.8M

Select item 452405712.

Structural Determinants for the Selective Anti-HIV-1 Activity of the All-β Alternative Conformer of XCL1

Christina Guzzo, Jamie C. Fox, Huiyi Miao, Brian F. Volkman, Paolo Lusso

J Virol. 2015 Sep 1; 89(17): 9061–9067. Published online 2015 Jun 17. doi: 10.1128/JVI.01285-15

PMCID:: PMC4524057

Abstract Article PDF–1.9M

Select item 445117813.

Structural Rearrangement of Human Lymphotactin, a C Chemokine, under Physiological Solution Conditions

E. Sonay Kuloğlu, Darrell R. McCaslin, John L. Markley, Brian F. Volkman

J Biol Chem. Author manuscript; available in PMC 2015 Jun 2.

Published in final edited form as: J Biol Chem. 2002 May 17; 277(20): 17863–17870. Published online 2002 Mar 11. doi: 10.1074/jbc.M200402200

PMCID:: PMC4451178

Abstract Article PDF–808K

Select item 429750814.

Structural and agonist properties of XCL2, the other member of the C-chemokine subfamily

Jamie C. Fox, Takashi Nakayama, Robert C. Tyler, Tara Sander, Osamu Yoshie, Brian F. Volkman

Cytokine. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Cytokine. 2015 Feb; 71(2): 302–311. Published online 2014 Dec 11. doi: 10.1016/j.cyto.2014.11.010

PMCID:: PMC4297508

Abstract Article PDF–1.4M

Select item 426658815.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 413636116.

Transcriptional and Posttranscriptional Regulation of Cytokine Gene Expression in HIV-1 Antigen-Specific CD8⁺ T Cells That Mediate Virus Inhibition

Tamika L. Payne, Jeff Blackinton, Alyse Frisbee, Joy Pickeral, Sheetal Sawant, Nathan A. Vandergrift, Stephanie A. Freel, Guido Ferrari, Jack D. Keene, Georgia D. Tomaras

J Virol. 2014 Sep; 88(17): 9514–9528. doi: 10.1128/JVI.00802-14