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Select item 106023781.

SARS-CoV-2 suppresses TLR4-induced immunity by dendritic cells via C-type lectin receptor DC-SIGN

Lieve E. H. van der Donk, Marta Bermejo-Jambrina, John L. van Hamme, Mette M. W. Volkers, Ad C. van Nuenen, Neeltje A. Kootstra, Teunis B. H. Geijtenbeek

PLoS Pathog. 2023 Oct; 19(10): e1011735. Published online 2023 Oct 16. doi: 10.1371/journal.ppat.1011735

PMCID:: PMC10602378

Abstract Article PDF–1.6M

Select item 93674752.

Human surfactant protein D facilitates SARS-CoV-2 pseudotype binding and entry in DC-SIGN expressing cells, and downregulates spike protein induced inflammation

Nazar Beirag, Chandan Kumar, Taruna Madan, Mohamed H. Shamji, Roberta Bulla, Daniel Mitchell, Valarmathy Murugaiah, Martin Mayora Neto, Nigel Temperton, Susan Idicula-Thomas, Praveen M. Varghese, Uday Kishore

Front Immunol. 2022; 13: 960733. Published online 2022 Jul 28. doi: 10.3389/fimmu.2022.960733

PMCID:: PMC9367475

Abstract Article PDF–4.8M

Select item 92555293.

Genetic polymorphisms in TLR3, IL10 and CD209 influence the risk of BK polyomavirus infection after kidney transplantation

Natalia Redondo, Isabel Rodríguez-Goncer, Patricia Parra, Francisco López-Medrano, Esther González, Ana Hernández, Hernando Trujillo, Tamara Ruiz-Merlo, Rafael San Juan, María Dolores Folgueira, Amado Andrés, José María Aguado, Mario Fernández-Ruiz

Sci Rep. 2022; 12: 11338. Published online 2022 Jul 5. doi: 10.1038/s41598-022-15406-0

PMCID:: PMC9255529

Abstract Article PDF–1.2M

Select item 91905174.

Association of CD209 (DC-SIGN) rs735240 SNV with paucibacillary leprosy in the Brazilian population and its functional effects

Giovanna Valle Germano, André Flores Braga, Rodrigo Mendes de Camargo, Priscila Betoni Ballalai, Ohanna Cavalcanti Bezerra, Fernanda Saloum de Neves Manta, Andréa de Faria Fernandes Belone, Cleverson Teixeira Soares, Pranab Kumar Das, Milton Ozório Moraes, Ana Carla Pereira Latini, Vânia Niéto Brito de Souza

Mem Inst Oswaldo Cruz. 2022; 117: e220014. Published online 2022 Jun 10. doi: 10.1590/0074-02760220014

PMCID:: PMC9190517

Abstract Article PDF–544K

Select item 87896585.

CD209/CD14⁺ Dendritic Cells Characterization in Rheumatoid and Psoriatic Arthritis Patients: Activation, Synovial Infiltration, and Therapeutic Targeting

Viviana Marzaioli, Mary Canavan, Achilleas Floudas, Keelin Flynn, Ronan Mullan, Douglas J. Veale, Ursula Fearon

Front Immunol. 2021; 12: 722349. Published online 2022 Jan 12. doi: 10.3389/fimmu.2021.722349

PMCID:: PMC8789658

Abstract Article PDF–14M

Select item 85912816.

DC-SIGN Mediates the Interaction Between Neutrophils and Leishmania amazonensis-Infected Dendritic Cells to Promote DC Maturation and Parasite Elimination

Rafael Tiburcio, Léon Dimitri Melo, Sara Nunes, Ana Luísa Augusto Barbosa, Elaine Carvalho de Oliveira, Martha Suarez, Valéria M. Borges, Natalia Tavares, Claudia Ida Brodskyn

Front Immunol. 2021; 12: 750648. Published online 2021 Nov 1. doi: 10.3389/fimmu.2021.750648

PMCID:: PMC8591281

Abstract Article PDF–16M

Select item 84578357.

A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance

Mohd Anisul, Jarrod Shilts, Jeremy Schwartzentruber, James Hayhurst, Annalisa Buniello, Elmutaz Shaikho Elhaj Mohammed, Jie Zheng, Michael Holmes, David Ochoa, Miguel Carmona, Joseph Maranville, Tom R Gaunt, Valur Emilsson, Vilmundur Gudnason, Ellen M McDonagh, Gavin J Wright, Maya Ghoussaini, Ian Dunham

eLife. 2021; 10: e69719. Published online 2021 Aug 17. doi: 10.7554/eLife.69719

PMCID:: PMC8457835

Abstract Article PDF–1.5M

Select item 84315368.

SARS-CoV-2 Impairs Dendritic Cells and Regulates DC-SIGN Gene Expression in Tissues

Guoshuai Cai, Mulong Du, Yohan Bossé, Helmut Albrecht, Fei Qin, Xizhi Luo, Xiao Michelle Androulakis, Chao Cheng, Mitzi Nagarkatti, Prakash Nagarkatti, David C. Christiani, Michael L. Whitfield, Christopher I. Amos, Feifei Xiao

Int J Mol Sci. 2021 Sep; 22(17): 9228. Published online 2021 Aug 26. doi: 10.3390/ijms22179228

PMCID:: PMC8431536

Abstract Article PDF–54M

Select item 84205059.

Identification of lectin receptors for conserved SARS‐CoV‐2 glycosylation sites

David Hoffmann, Stefan Mereiter, Yoo Jin Oh, Vanessa Monteil, Elizabeth Elder, Rong Zhu, Daniel Canena, Lisa Hain, Elisabeth Laurent, Clemens Grünwald‐Gruber, Miriam Klausberger, Gustav Jonsson, Max J Kellner, Maria Novatchkova, Melita Ticevic, Antoine Chabloz, Gerald Wirnsberger, Astrid Hagelkruys, Friedrich Altmann, Lukas Mach, Johannes Stadlmann, Chris Oostenbrink, Ali Mirazimi, Peter Hinterdorfer, Josef M Penninger

EMBO J. 2021 Oct 1; 40(19): e108375. Published online 2021 Aug 23. doi: 10.15252/embj.2021108375

PMCID:: PMC8420505

Abstract Article PDF–5.3M

Select item 840270510.

Suppression of DC-SIGN and gH Reveals Complex, Subset-Specific Mechanisms for KSHV Entry in Primary B Lymphocytes

Nancy Palmerin, Farizeh Aalam, Romina Nabiee, Murali Muniraju, Javier Gordon Ogembo, Jennifer Totonchy

Viruses. 2021 Aug; 13(8): 1512. Published online 2021 Jul 31. doi: 10.3390/v13081512

PMCID:: PMC8402705

Abstract Article PDF–2.6M

Select item 826554311.

CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2

Razie Amraei, Wenqing Yin, Marc A. Napoleon, Ellen L. Suder, Jacob Berrigan, Qing Zhao, Judith Olejnik, Kevin Brown Chandler, Chaoshuang Xia, Jared Feldman, Blake M. Hauser, Timothy M. Caradonna, Aaron G. Schmidt, Suryaram Gummuluru, Elke Mühlberger, Vipul Chitalia, Catherine E. Costello, Nader Rahimi

ACS Cent Sci. 2021 Jul 28; 7(7): 1156–1165. Published online 2021 Jun 30. doi: 10.1021/acscentsci.0c01537

PMCID:: PMC8265543

Abstract Article PDF–10M

Select item 817572212.

DC-SIGN binding to mannosylated B-cell receptors in follicular lymphoma down-modulates receptor signaling capacity

Beatriz Valle-Argos, Giorgia Chiodin, Dean J. Bryant, Joe Taylor, Elizabeth Lemm, Patrick J. Duriez, Philip J. Rock, Jonathan C. Strefford, Francesco Forconi, Richard W. Burack, Graham Packham, Freda K. Stevenson

Sci Rep. 2021; 11: 11676. Published online 2021 Jun 3. doi: 10.1038/s41598-021-91112-7

PMCID:: PMC8175722

Abstract Article PDF–4.1M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 813666514.

DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist

Michel Thépaut, Joanna Luczkowiak, Corinne Vivès, Nuria Labiod, Isabelle Bally, Fátima Lasala, Yasmina Grimoire, Daphna Fenel, Sara Sattin, Nicole Thielens, Guy Schoehn, Anna Bernardi, Rafael Delgado, Franck Fieschi

PLoS Pathog. 2021 May; 17(5): e1009576. Published online 2021 May 20. doi: 10.1371/journal.ppat.1009576

PMCID:: PMC8136665

Abstract Article PDF–2.9M

Select item 812831315.

A novel CD209 polymorphism is associated with rheumatoid arthritis patients in Taiwan

Hua‐Chen Chan, Shu‐Chen Wang, Chia‐Hui Lin, Yuan‐Zhao Lin, Ruei‐Nian Li, Jeng‐Hsien Yen

J Clin Lab Anal. 2021 May; 35(5): e23751. Published online 2021 Apr 1. doi: 10.1002/jcla.23751

PMCID:: PMC8128313

Abstract Article PDF–576K

Select item 810688316.

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2

Qiao Lu, Jia Liu, Shuai Zhao, Maria Florencia Gomez Castro, Maudry Laurent-Rolle, Jianbo Dong, Xiaojuan Ran, Payal Damani-Yokota, Hongzhen Tang, Triantafyllia Karakousi, Juhee Son, Maria E. Kaczmarek, Ze Zhang, Stephen T. Yeung, Broc T. McCune, Rita E. Chen, Fei Tang, Xianwen Ren, Xufeng Chen, Jack C.C. Hsu, Marianna Teplova, Betty Huang, Haijing Deng, Zhilin Long, Tenny Mudianto, Shumin Jin, Peng Lin, Jasper Du, Ruochen Zang, Tina Tianjiao Su, Alberto Herrera, Ming Zhou, Renhong Yan, Jia Cui, James Zhu, Qiang Zhou, Tao Wang, Jianzhu Ma, Sergei B. Koralov, Zemin Zhang, Iannis Aifantis, Leopoldo N. Segal, Michael S. Diamond, Kamal M. Khanna, Kenneth A. Stapleford, Peter Cresswell, Yue Liu, Siyuan Ding, Qi Xie, Jun Wang

Immunity. 2021 Jun 8; 54(6): 1304–1319.e9. Published online 2021 May 9. doi: 10.1016/j.immuni.2021.05.006

PMCID:: PMC8106883

Abstract Article PDF–5.6M

Select item 790966217.

In silico screening and identification of deleterious missense SNPs along with their effects on CD-209 gene: An insight to CD-209 related-diseases

Mohib Ullah Kakar, Muhammad Matloob, Rongji Dai, Yulin Deng, Kifayat Ullah, Ihsan Ullah Kakar, Ghulam Khaliq, Muhammad Umer, Zhoaib Ahmed Bhutto, Sarfarz Ali Fazlani, Muhammad Zubair Mehboob

PLoS One. 2021; 16(2): e0247249. Published online 2021 Feb 26. doi: 10.1371/journal.pone.0247249

Correction in:: PLoS One. 2022; 17(7): e0271144.

PMCID:: PMC7909662

Abstract Article PDF–2.3M

Select item 789848218.

Synthesis of Asparagine Derivatives Harboring a Lewis X Type DC‐SIGN Ligand and Evaluation of their Impact on Immunomodulation in Multiple Sclerosis

Ward Doelman, Dr. Mikkel H. S. Marqvorsen, Dr. Fabrizio Chiodo, Sven C. M. Bruijns, Prof. Gijsbert A. van der Marel, Prof. Yvette van Kooyk, Dr. Sander I. van Kasteren, Dr. Can Araman

Chemistry. 2021 Feb 5; 27(8): 2742–2752. Published online 2020 Dec 28. doi: 10.1002/chem.202004076

PMCID:: PMC7898482

Abstract Article PDF–1.4M

Select item 789431819.

Structural Characterization of N‐Linked Glycans in the Receptor Binding Domain of the SARS‐CoV‐2 Spike Protein and their Interactions with Human Lectins

Maria Pia Lenza, Iker Oyenarte, Dr. Tammo Diercks, Jon Imanol Quintana, Dr. Ana Gimeno, Dr. Helena Coelho, Ana Diniz, Dr. Francesca Peccati, Sandra Delgado, Alexandre Bosch, Dr. Mikel Valle, Dr. Oscar Millet, Prof. Dr. Nicola G. A. Abrescia, Dr. Asís Palazón, Dr. Filipa Marcelo, Dr. Gonzalo Jiménez‐Osés, Prof. Dr. Jesús Jiménez‐Barbero, Dr. Ana Ardá, Dr. June Ereño‐Orbea

Angew Chem Int Ed Engl. 2020 Dec 21; 59(52): 23763–23771. Published online 2020 Oct 22. doi: 10.1002/anie.202011015

PMCID:: PMC7894318

Abstract Article PDF–2.3M

Select item 782086620.

Proteus mirabilis Targets Atherosclerosis Plaques in Human Coronary Arteries via DC-SIGN (CD209)

Ying Xue, Qiao Li, Chae Gyu Park, John D. Klena, Andrey P. Anisimov, Ziyong Sun, Xiang Wei, Tie Chen

Front Immunol. 2020; 11: 579010. Published online 2021 Jan 8. doi: 10.3389/fimmu.2020.579010

PMCID:: PMC7820866

Abstract Article PDF–6.2M

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