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Items: 1 to 20 of 128

1.
Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia
Yanfei Wang, Xiaoyu Xiao, Qiuqiu Lin, Rong Song, Xiaozhou Wang, Yiji Liang, Jingsong Chen, Xiaojun Luan, Zhiguang Zhou, Yang Xiao, Yaoming Xue, Jingyi Hu
J Diabetes Investig. 2024 Jan; 15(1): 121–130. Published online 2023 Sep 22. doi: 10.1111/jdi.14084
PMCID:
PMC10759714
AbstractArticlePDF–876K
2.
Dysregulation of HNF1B/Clusterin axis enhances disease progression in a highly aggressive subset of pancreatic cancer patients
Shouhui Yang, Wei Tang, Azadeh Azizian, Jochen Gaedcke, Philipp Ströbel, Limin Wang, Helen Cawley, Yuuki Ohara, Paloma Valenzuela, Lin Zhang, Trisha Lal, Sanju Sinha, Eythan Rupin, Nader Hanna, B Michael Ghadimi, S Perwez Hussain
Carcinogenesis. 2022 Dec; 43(12): 1198–1210. Published online 2022 Nov 25. doi: 10.1093/carcin/bgac092
PMCID:
PMC10122429
AbstractArticlePDF–62M
3.
HNF1B Alters an Evolutionarily Conserved Nephrogenic Program of Target Genes
Kelli Grand, Martine Stoltz, Ludovica Rizzo, Ruth Röck, Michael M. Kaminski, Gabriela Salinas, Maike Getwan, Thomas Naert, Roman Pichler, Soeren S. Lienkamp
J Am Soc Nephrol. 2023 Mar; 34(3): 412–432. Published online 2022 Dec 15. doi: 10.1681/ASN.2022010076
PMCID:
PMC10103355
AbstractArticle
4.
HNF1B‐driven three‐dimensional chromatin structure for molecular classification in pancreatic cancers
Hiroyuki Kato, Keisuke Tateishi, Dosuke Iwadate, Keisuke Yamamoto, Hiroaki Fujiwara, Takuma Nakatsuka, Yotaro Kudo, Yoku Hayakawa, Hideaki Ijichi, Motoyuki Otsuka, Takahiro Kishikawa, Ryota Takahashi, Koji Miyabayashi, Yousuke Nakai, Yoshihiro Hirata, Atsushi Toyoda, Shinichi Morishita, Mitsuhiro Fujishiro
Cancer Sci. 2023 Apr; 114(4): 1672–1685. Published online 2022 Dec 25. doi: 10.1111/cas.15690
PMCID:
PMC10067390
AbstractArticlePDF–4.3M
5.
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection
Jin Wei, Ajinkya Patil, Clayton K. Collings, Mia Madel Alfajaro, Yu Liang, Wesley L. Cai, Madison S. Strine, Renata B. Filler, Peter C. DeWeirdt, Ruth E. Hanna, Bridget L. Menasche, Arya Ökten, Mario A. Peña-Hernández, Jon Klein, Andrew McNamara, Romel Rosales, Briana L. McGovern, M. Luis Rodriguez, Adolfo García-Sastre, Kris M. White, Yiren Qin, John G. Doench, Qin Yan, Akiko Iwasaki, Thomas P. Zwaka, Jun Qi, Cigall Kadoch, Craig B. Wilen
Nat Genet. 2023; 55(3): 471–483. Published online 2023 Mar 9. doi: 10.1038/s41588-023-01307-z
PMCID:
PMC10011139
AbstractArticlePDF–21M
6.
Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer–Rokitansky–Küster–Hauser syndrome
Ella Thomson, Minh Tran, Gorjana Robevska, Katie Ayers, Jocelyn van der Bergen, Prarthna Gopalakrishnan Bhaskaran, Eric Haan, Silvia Cereghini, Alla Vash-Margita, Miranda Margetts, Alison Hensley, Quan Nguyen, Andrew Sinclair, Peter Koopman, Emanuele Pelosi
Hum Mol Genet. 2023 Mar 15; 32(6): 1032–1047. Published online 2022 Oct 25. doi: 10.1093/hmg/ddac262
PMCID:
PMC9990990
AbstractArticlePDF–2.2M
7.
The Landscape of HNF1B Deficiency: A Syndrome Not Yet Fully Explored
Alessandro Gambella, Silvia Kalantari, Massimiliano Cadamuro, Marco Quaglia, Maurizio Delvecchio, Luca Fabris, Michele Pinon
Cells. 2023 Jan; 12(2): 307. Published online 2023 Jan 13. doi: 10.3390/cells12020307
PMCID:
PMC9856658
AbstractArticlePDF–1.7M
8.
Elevated level of lysophosphatidic acid among patients with HNF1B mutations and its role in RCAD syndrome: a multiomic study
Beata Małachowska, Justyna Janikiewicz, Karolina Pietrowska, Krystyna Wyka, Joanna Madzio, Kamila Wypyszczak, Marcin Tkaczyk, Sławomir Chrul, Rafał Zwiech, Anna Hogendorf, Maciej T. Małecki, Maciej Borowiec, Adam Krętowski, Wojciech Młynarski, Agnieszka Dobrzyń, Michał Ciborowski, Wojciech Fendler
Metabolomics. 2022; 18(3): 15. Published online 2022 Feb 18. doi: 10.1007/s11306-022-01873-z
PMCID:
PMC8857088
AbstractArticlePDF–1.5M
9.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
10.
Comprehensive quantitative analysis of alternative splicing variants reveals the HNF1B mRNA splicing pattern in various tumour and non-tumour tissues
Jan Hojny, Romana Michalkova, Eva Krkavcova, Quang Hiep Bui, Michaela Bartu, Kristyna Nemejcova, Marta Kalousova, Petra Kleiblova, Pavel Dundr, Ivana Struzinska
Sci Rep. 2022; 12: 199. Published online 2022 Jan 7. doi: 10.1038/s41598-021-03989-z
PMCID:
PMC8741901
AbstractArticlePDF–1.9M
11.
Modeling HNF1B-associated monogenic diabetes using human iPSCs reveals an early stage impairment of the pancreatic developmental program
Ranna El-Khairi, Evelyn Olszanowski, Daniele Muraro, Pedro Madrigal, Katarzyna Tilgner, Mariya Chhatriwala, Sapna Vyas, Crystal Y. Chia, Ludovic Vallier, Santiago A. Rodríguez-Seguí
Stem Cell Reports. 2021 Sep 14; 16(9): 2289–2304. Published online 2021 Aug 26. doi: 10.1016/j.stemcr.2021.07.018
PMCID:
PMC8452540
AbstractArticlePDF–6.8M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Hepatocyte nuclear factor 1 beta: A perspective in cancer
Shubhra Chandra, Srilakshmi Srinivasan, Jyotsna Batra
Cancer Med. 2021 Mar; 10(5): 1791–1804. Published online 2021 Feb 13. doi: 10.1002/cam4.3676
PMCID:
PMC7940219
AbstractArticlePDF–548K
14.
HNF1B inhibits cell proliferation via repression of SMAD6 expression in prostate cancer
Wei Lu, Jian Sun, Huihui Zhou, Fei Wang, Chunchun Zhao, Kai Li, Caibin Fan, Guanxiong Ding, Jianqing Wang
J Cell Mol Med. 2020 Dec; 24(24): 14539–14548. Published online 2020 Nov 10. doi: 10.1111/jcmm.16081
PMCID:
PMC7754016
AbstractArticlePDF–1.1M
15.
Integrative Analysis of HNF1B mRNA in Human Cancers Based on Data Mining
Chunhui Nie, Bei Wang, Baoquan Wang, Ning Lv, Enfan Zhang
Int J Med Sci. 2020; 17(18): 2895–2904. Published online 2020 Oct 18. doi: 10.7150/ijms.51213
PMCID:
PMC7646120
AbstractArticlePDF–2.6M
16.
Exploiting TRIM37-driven centrosome dysfunction to kill breast cancer cells
Zhong Y. Yeow, Bramwell G. Lambrus, Rebecca Marlow, Kevin H. Zhan, Mary-Anne Durin, Lauren T. Evans, Phillip M. Scott, Thao Phan, Elizabeth Park, Lorena A. Ruiz, Daniela Moralli, Eleanor G. Knight, Luned M. Badder, Daniela Novo, Syed Haider, Catherine M. Green, Andrew NJ Tutt, Christopher J Lord, J. Ross Chapman, Andrew J. Holland
Nature. Author manuscript; available in PMC 2021 Sep 9.
Published in final edited form as: Nature. 2020 Sep; 585(7825): 447–452. Published online 2020 Sep 9. doi: 10.1038/s41586-020-2690-1
PMCID:
PMC7597367
AbstractArticlePDF–1.7M
17.
Analysis of expression, epigenetic, and genetic changes of HNF1B in 130 kidney tumours
Michaela Bártů, Jan Hojný, Nikola Hájková, Romana Michálková, Eva Krkavcová, Ladislav Hadravský, Lenka Kleissnerová, Quang Hiep Bui, Ivana Stružinská, Kristýna Němejcová, Otakar Čapoun, Monika Šlemendová, Pavel Dundr
Sci Rep. 2020; 10: 17151. Published online 2020 Oct 13. doi: 10.1038/s41598-020-74059-z
PMCID:
PMC7555858
AbstractArticlePDF–4.3M
18.
Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation
Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux
Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070
PMCID:
PMC7290721
AbstractArticlePDF–9.2M
19.
Influence of IGF2BP2, HMG20A, and HNF1B genetic polymorphisms on the susceptibility to Type 2 diabetes mellitus in Chinese Han population
Ting Huang, Li Wang, Mei Bai, Jianwen Zheng, Dongya Yuan, Yongjun He, Yuhe Wang, Tianbo Jin, Wei Cui
Biosci Rep. 2020 May 29; 40(5): BSR20193955. Published online 2020 May 28. doi: 10.1042/BSR20193955
PMCID:
PMC7256674
AbstractArticlePDF–757K
20.
A cross‐sectional study of patients referred for HNF1B‐MODY genetic testing due to cystic kidneys and diabetes
Paweł Sztromwasser, Arkadiusz Michalak, Beata Małachowska, Paulina Młudzik, Karolina Antosik, Anna Hogendorf, Agnieszka Zmysłowska, Maciej Borowiec, Wojciech Młynarski, Wojciech Fendler
Pediatr Diabetes. 2020 May; 21(3): 422–430. Published online 2020 Jan 29. doi: 10.1111/pedi.12959
PMCID:
PMC7217165
AbstractArticlePDF–1.8M

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