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Items: 1 to 20 of 28

1.
ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9
Lena Cook, Marie Sengelmann, Birte Winkler, Constanze Nagl, Sarah Koch, Uwe Schlomann, Emily P. Slater, Miles A. Miller, Elke Pogge von Strandmann, Bastian Dörsam, Christian Preußer, Jörg W. Bartsch
Int J Mol Sci. 2022 Feb; 23(4): 1976. Published online 2022 Feb 10. doi: 10.3390/ijms23041976
PMCID:
PMC8875419
AbstractArticlePDF–3.5M
2.
Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells
Tanzeela Awan, Aaron Babendreyer, Abid Mahmood Alvi, Stefan Düsterhöft, Daniela Lambertz, Jörg W. Bartsch, Christian Liedtke, Andreas Ludwig
J Cell Mol Med. 2021 Feb; 25(4): 1982–1999. Published online 2020 Dec 13. doi: 10.1111/jcmm.16015
PMCID:
PMC7882935
AbstractArticlePDF–3.1M
3.
A disintegrin and metalloproteinase 8 induced epithelial‐mesenchymal transition to promote the invasion of colon cancer cells via TGF‐β/Smad2/3 signalling pathway
Qianna Jin, Xin Jin, Tao Liu, Xiaoming Lu, Guobin Wang, Nan He
J Cell Mol Med. 2020 Nov; 24(22): 13058–13069. Published online 2020 Sep 20. doi: 10.1111/jcmm.15907
PMCID:
PMC7701584
AbstractArticlePDF–2.0M
4.
A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric Cancer
Hye Won Chung, Jin Ju Kim, Jae Il Choi, Hae Rim Lee, Jong-Baeck Lim
Yonsei Med J. 2019 Aug 1; 60(8): 713–719. Published online 2019 Jul 19. doi: 10.3349/ymj.2019.60.8.713
PMCID:
PMC6660445
AbstractArticlePDF–226K
5.
A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease
Francesca Polverino, Joselyn Rojas-Quintero, Xiaoyun Wang, Hans Petersen, Li Zhang, Xiaoyan Gai, Andrew Higham, Duo Zhang, Kushagra Gupta, Amit Rout, Ilyas Yambayev, Victor Pinto-Plata, Lynette M. Sholl, Danen Cunoosamy, Bartolomé R. Celli, James Goldring, Dave Singh, Yohannes Tesfaigzi, Jadwiga Wedzicha, Henric Olsson, Caroline A. Owen
Am J Respir Crit Care Med. 2018 Nov 15; 198(10): 1254–1267. Published online 2018 Nov 15. doi: 10.1164/rccm.201707-1331OC
PMCID:
PMC6290938
AbstractArticlePDF–1.7M
6.
ADAM8 Is an Antigen of Tyrosine Kinase Inhibitor-Resistant Chronic Myeloid Leukemia Cells Identified by Patient-Derived Induced Pluripotent Stem Cells
Masashi Miyauchi, Junji Koya, Shunya Arai, Sho Yamazaki, Akira Honda, Keisuke Kataoka, Akihide Yoshimi, Kazuki Taoka, Keiki Kumano, Mineo Kurokawa
Stem Cell Reports. 2018 Mar 13; 10(3): 1115–1130. Published online 2018 Feb 8. doi: 10.1016/j.stemcr.2018.01.015
PMCID:
PMC5919294
AbstractArticlePDF–3.7M
7.
The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion
M Swayampakula, P C McDonald, M Vallejo, E Coyaud, S C Chafe, A Westerback, G Venkateswaran, J Shankar, G Gao, E M N Laurent, Y Lou, K L Bennewith, C T Supuran, I R Nabi, B Raught, S Dedhar
Oncogene. 2017 Nov 9; 36(45): 6244–6261. Published online 2017 Jul 10. doi: 10.1038/onc.2017.219
PMCID:
PMC5684442
AbstractArticlePDF–4.4M
8.
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell
Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8
PMCID:
PMC5630600
AbstractArticlePDF–2.3M
9.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
10.
ADAM8 as a drug target in Pancreatic Cancer
Uwe Schlomann, Garrit Koller, Catharina Conrad, Taheera Ferdous, Panagiota Golfi, Adolfo Molejon Garcia, Sabrina Höfling, Maddy Parsons, Patricia Costa, Robin Soper, Maud Bossard, Thorsten Hagemann, Rozita Roshani, Norbert Sewald, Randal R. Ketchem, Marcia L. Moss, Fred H. Rasmussen, Miles A. Miller, Douglas A. Lauffenburger, David A. Tuveson, Christopher Nimsky, Jörg W. Bartsch
Nat Commun. Author manuscript; available in PMC 2016 Sep 7.
Published in final edited form as: Nat Commun. 2015; 6: 6175. Published online 2015 Jan 28. doi: 10.1038/ncomms7175
PMCID:
PMC5014123
AbstractArticlePDF–3.4M
11.
miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells
Sonia G. Das, Mathilde Romagnoli, Nora D. Mineva, Sophie Barillé-Nion, Pascal Jézéquel, Mario Campone, Gail E. Sonenshein
Breast Cancer Res. 2016; 18: 40. Published online 2016 Apr 2. doi: 10.1186/s13058-016-0699-z
PMCID:
PMC4818899
AbstractArticlePDF–2.4M
12.
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells
Fangyong Dong, Michael Eibach, Jörg W. Bartsch, Amalia M. Dolga, Uwe Schlomann, Catharina Conrad, Susanne Schieber, Oliver Schilling, Martin L. Biniossek, Carsten Culmsee, Herwig Strik, Garrit Koller, Barbara Carl, Christopher Nimsky
Neuro Oncol. 2015 Nov; 17(11): 1474–1485. Published online 2015 Mar 29. doi: 10.1093/neuonc/nov042
PMCID:
PMC4648299
AbstractArticlePDF–1.0M
13.
ADAM8 expression is associated with increased invasiveness and reduced patient survival in pancreatic cancer
N Valkovskaya, H Kayed, K Felix, D Hartmann, N A Giese, S P Osinsky, H Friess, J Kleeff
J Cell Mol Med. 2007 Sep; 11(5): 1162–1174. Published online 2007 Jul 17. doi: 10.1111/j.1582-4934.2007.00082.x
PMCID:
PMC4401277
AbstractArticlePDF–663K
14.
Preferred SH3 Domain Partners of ADAM Metalloproteases Include Shared and ADAM-Specific SH3 Interactions
Iivari Kleino, Annika Järviluoma, Jussi Hepojoki, Ari Pekka Huovila, Kalle Saksela
PLoS One. 2015; 10(3): e0121301. Published online 2015 Mar 31. doi: 10.1371/journal.pone.0121301
PMCID:
PMC4380453
AbstractArticlePDF–2.3M
15.
N-Glycosylation Regulates ADAM8 Processing and Activation
Srimathi Srinivasan, Mathilde Romagnoli, Andrew Bohm, Gail E. Sonenshein
J Biol Chem. 2014 Nov 28; 289(48): 33676–33688. Published online 2014 Oct 21. doi: 10.1074/jbc.M114.594242
PMCID:
PMC4246118
AbstractArticlePDF–2.4M
16.
Fibronectin fragments and the cleaving enzyme ADAM-8 in the degenerative human intervertebral disc
Nancy Ruel, Dessislava Z. Markova, Sherrill L. Adams, Carla Scanzello, Gabriella Cs-Szabo, David Gerard, Peng Shi, D. Greg Anderson, Marc Zack, Howard S. An, Di Chen, Yejia Zhang
Spine (Phila Pa 1976) Author manuscript; available in PMC 2015 Jul 15.
Published in final edited form as: Spine (Phila Pa 1976). 2014 Jul 15; 39(16): 1274–1279. doi: 10.1097/BRS.0000000000000397
PMCID:
PMC4229950
AbstractArticlePDF–788K
17.
Expression of A disintegrin and metalloprotease 8 is associated with cell growth and poor survival in colorectal cancer
Zuli Yang, Yang Bai, Lijun Huo, Hao Chen, Jintuan Huang, Jizheng Li, Xinjuan Fan, Zihuan Yang, Lei Wang, Jianping Wang
BMC Cancer. 2014; 14: 568. Published online 2014 Aug 7. doi: 10.1186/1471-2407-14-568
PMCID:
PMC4141088
AbstractArticlePDF–1.5M
18.
ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis
Mathilde Romagnoli, Nora D Mineva, Michael Polmear, Catharina Conrad, Srimathi Srinivasan, Delphine Loussouarn, Sophie Barillé-Nion, Irene Georgakoudi, Áine Dagg, Enda W McDermott, Michael J Duffy, Patricia M McGowan, Uwe Schlomann, Maddy Parsons, Jörg W Bartsch, Gail E Sonenshein
EMBO Mol Med. 2014 Feb; 6(2): 278–294. Published online 2013 Dec 27. doi: 10.1002/emmm.201303373
PMCID:
PMC3927960
AbstractArticlePDF–2.1M
19.
A New Paradigm for Enzymatic Control of α-Cleavage and β-Cleavage of the Prion Protein
Alex J. McDonald, Jessie P. Dibble, Eric G. B. Evans, Glenn L. Millhauser
J Biol Chem. 2014 Jan 10; 289(2): 803–813. Published online 2013 Nov 18. doi: 10.1074/jbc.M113.502351
PMCID:
PMC3887206
AbstractArticlePDF–2.1M
20.
Adam8 Limits the Development of Allergic Airway Inflammation in Mice
Martin D. Knolle, Takahiro Nakajima, Anja Hergrueter, Kushagra Gupta, Francesca Polverino, Vanessa J. Craig, Susanne E. Fyfe, Muhammad Zahid, Perdita Permaul, Manuela Cernadas, Gilbert Montano, Yohannes Tesfaigzi, Lynette Sholl, Lester Kobzik, Elliot Israel, Caroline A. Owen
J Immunol. Author manuscript; available in PMC 2014 Jun 15.
Published in final edited form as: J Immunol. 2013 Jun 15; 190(12): 6434–6449. Published online 2013 May 13. doi: 10.4049/jimmunol.1202329
PMCID:
PMC3679335
AbstractArticlePDF–5.0M

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