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Select item 112359381.

GGC expansions in NOTCH2NLC contribute to Parkinson disease and dopaminergic neuron degeneration

Qiong Liu, Juan Chen, Jin Xue, Xun Zhou, Yun Tian, Qiao Xiao, Wen Huang, Yongcheng Pan, Xiaoxia Zhou, Jian Li, Yuwen Zhao, Hongxu Pan, Yige Wang, Runcheng He, Yaqin Xiang, Tian Tu, Qian Xu, Qiying Sun, Jieqiong Tan, Xinxiang Yan, Jinchen Li, Jifeng Guo, Lu Shen, Ranhui Duan, Beisha Tang, Zhenhua Liu

Eur J Neurol. 2024 Feb; 31(2): e16145. Published online 2023 Nov 17. doi: 10.1111/ene.16145

PMCID:: PMC11235938

Abstract Article PDF–14M

Select item 111915212.

CircLZIC regulates ox-LDL-induced HUVEC cell proliferation and apoptosis via Micro-330-5p/NOTCH2 axis in atherosclerosis

Xingping Men, Aizhen Hu, Tingting Xu

Clin Hemorheol Microcirc. 2024; 87(1): 115–127. Prepublished online 2024 Jan 25. Published online 2024 Jun 13. doi: 10.3233/CH-232063

PMCID:: PMC11191521

Abstract Article PDF–698K

Select item 111718013.

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry

Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J. Gibbings, Laura Trinkle-Mulcahy, John W. Copeland

Int J Mol Sci. 2024 Jun; 25(11): 5686. Published online 2024 May 23. doi: 10.3390/ijms25115686

PMCID:: PMC11171801

Abstract Article PDF–3.1M

Select item 111588734.

Gain‐of‐function mutations and copy number increases of Notch2 in diffuse large B‐cell lymphoma

Suk‐young Lee, Keiki Kumano, Kumi Nakazaki, Masashi Sanada, Akihiko Matsumoto, Go Yamamoto, Yasuhito Nannya, Ritsuro Suzuki, Satoshi Ota, Yasunori Ota, Koji Izutsu, Mamiko Sakata‐Yanagimoto, Akira Hangaishi, Hideo Yagita, Masashi Fukayama, Masao Seto, Mineo Kurokawa, Seishi Ogawa, Shigeru Chiba

Cancer Sci. 2009 May; 100(5): 920–926. Published online 2009 Mar 25. doi: 10.1111/j.1349-7006.2009.01130.x

PMCID:: PMC11158873

Abstract Article PDF–12M

Select item 110494335.

Investigating Repeat Expansions in NIPA1, NOP56, and NOTCH2NLC Genes: A Closer Look at Amyotrophic Lateral Sclerosis Patients from Southern Italy

Paola Ruffo, Francesca De Amicis, Vincenzo La Bella, Francesca Luisa Conforti

Cells. 2024 Apr; 13(8): 677. Published online 2024 Apr 14. doi: 10.3390/cells13080677

PMCID:: PMC11049433

Abstract Article PDF–1.6M

Select item 109168666.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 106277867.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 103516608.

Genetic spectrum and clinical features of adult leukoencephalopathies in a Chinese cohort

Minglei Liu, Yangyang Wang, Changhe Shi, Yanpeng Yuan, Lanjun Li, Xiaoyun Zhang, Yuming Xu, Jing Yang

Ann Clin Transl Neurol. 2023 Jul; 10(7): 1119–1135. Published online 2023 May 26. doi: 10.1002/acn3.51794

PMCID:: PMC10351660

Abstract Article PDF–5.3M

Select item 103232529.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 1017698010.

NOTCH2NLC expanded GGC repeats in patients with cerebral small vessel disease

Yun-chao Wang, Yu Fan, Wen-Kai Yu, Si Shen, Jia-Di Li, Yuan Gao, Yan Ji, Yu-Sheng Li, Lu-Lu Yu, Zi-Chen Zhao, Shan-Shan Li, Yao Ding, Chang-He Shi, Yu-ming Xu

Stroke Vasc Neurol. 2023 Apr; 8(2): 161–168. Published online 2022 Oct 7. doi: 10.1136/svn-2022-001631

PMCID:: PMC10176980

Abstract Article PDF–1.4M

Select item 1015276711.

NOTCH2NLC GGC repeat expansion causes retinal pathology with intranuclear inclusions throughout the retina and causes visual impairment

Jun Sone, Shinji Ueno, Akio Akagi, Hiroaki Miyahara, Chisato Tamai, Yuichi Riku, Hiroyuki Yabata, Ryuichi Koizumi, Tomohiro Hattori, Hiroshi Hirose, Yoshito Koyanagi, Rei Kobayashi, Hisashi Okada, Yoshiyuki Kishimoto, Yoshio Hashizume, Gen Sobue, Mari Yoshida, Yasushi Iwasaki

Acta Neuropathol Commun. 2023; 11: 71. Published online 2023 May 2. doi: 10.1186/s40478-023-01564-3

PMCID:: PMC10152767

Abstract Article PDF–2.3M

Select item 1012273612.

DTX2通过Notch2/Akt轴促进结直肠癌细胞的迁移和侵袭

马振南, 赵雪峰, 张晓微, 许广大, 刘福全

Nan Fang Yi Ke Da Xue Xue Bao. 2023 Mar 20; 43(3): 340–348. Chinese. doi: 10.12122/j.issn.1673-4254.2023.03.02

PMCID:: PMC10122736

Abstract Article PDF–3.3M

Select item 1003393713.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 995047114.

NOTCH2NLC GGC repeats are not expanded in Italian amyotrophic lateral sclerosis patients

Arianna Manini, Delia Gagliardi, Megi Meneri, Sara Antognozzi, Roberto Del Bo, Giacomo Pietro Comi, Stefania Corti, Dario Ronchi

Sci Rep. 2023; 13: 3187. Published online 2023 Feb 23. doi: 10.1038/s41598-023-30393-6

PMCID:: PMC9950471

Abstract Article PDF–866K

Select item 955211815.

Claudin-4 localization in epithelial ovarian cancer

Margaret C. Neville, Patricia G. Webb, Heidi K. Baumgartner, Benjamin G. Bitler

Heliyon. 2022 Oct; 8(10): e10862. Published online 2022 Oct 4. doi: 10.1016/j.heliyon.2022.e10862

PMCID:: PMC9552118

Abstract Article PDF–4.5M

Select item 948193316.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 943393817.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 926261418.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 923162319.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 917141120.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

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PMC Links for GEO Profiles (Select 125854623) (231)
PMC
Nucleotide Links for Gene (Select 19891) (12)
Nucleotide
Mus musculus CREB regulated transcription coactivator 3 (Crtc3), mRNA
Mus musculus CREB regulated transcription coactivator 3 (Crtc3), mRNA
gi|2648594311|ref|NM_173863.3|

Nucleotide
Mus musculus vav 3 oncogene (Vav3), transcript variant 1, mRNA
Mus musculus vav 3 oncogene (Vav3), transcript variant 1, mRNA
gi|69724857|ref|NM_020505.2|

Nucleotide
Mus musculus signal recognition particle 54A (Srp54a), transcript variant 1, mRN...
Mus musculus signal recognition particle 54A (Srp54a), transcript variant 1, mRNA
gi|2325215043|ref|NM_011899.5|

Nucleotide

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