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Items: 1 to 20 of 38

1.
Interaction of the C9orf72-Amyotrophic Lateral Sclerosis-Related Proline–Arginine Dipeptide Repeat Protein with the RNA-Binding Protein NOVA1 Causes Decreased Expression of UNC13A Due to Enhanced Inclusion of Cryptic Exons, Which Is Reversed by Betulin Treatment
Ru-Huei Fu, Hui-Jye Chen, Syuan-Yu Hong
Cells. 2023 Oct; 12(20): 2476. Published online 2023 Oct 18. doi: 10.3390/cells12202476
PMCID:
PMC10605128
AbstractArticlePDF–12M
2.
NOVA1 prevents overactivation of the unfolded protein response and facilitates chromatin access during human white adipogenesis
Zhigang Yang, Ping Dong, Jiankun Cao, Na Lin, Shize Ma, Rui Cao, Lei Cai, Lei Wang, Changchang Cao, Yuanchao Xue, Jing Pan, Xiu Li, Kang Wang, Qiwei Liu, Chen Li, Fuxing Gong, Xin Fu, Ran Xiao
Nucleic Acids Res. 2023 Jul 21; 51(13): 6981–6998. Published online 2023 May 29. doi: 10.1093/nar/gkad469
PMCID:
PMC10359595
AbstractArticlePDF–2.9M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis
Florian Krach, Emily C. Wheeler, Martin Regensburger, Tom Boerstler, Holger Wend, Anthony Q. Vu, Ruth Wang, Stephanie Reischl, Karsten Boldt, Ranjan Batra, Stefan Aigner, John Ravits, Juergen Winkler, Gene W. Yeo, Beate Winner
Acta Neuropathol. 2022; 144(3): 413–435. Published online 2022 Jul 1. doi: 10.1007/s00401-022-02450-3
PMCID:
PMC9381448
AbstractArticlePDF–7.7M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Roles of the microRNA-338-3p/NOVA1 axis in retinoblastoma
Shoubin Sun, Runze Wang, Sisi Yi, Sijia Li, Lei Wang, Jianwen Wang
Mol Med Rep. 2021 May; 23(5): 394. Published online 2021 Mar 22. doi: 10.3892/mmr.2021.12033
PMCID:
PMC8008220
AbstractArticlePDF–6.2M
7.
Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment
Cleber A. Trujillo, Edward S. Rice, Nathan K. Schaefer, Isaac A. Chaim, Emily C. Wheeler, Assael A. Madrigal, Justin Buchanan, Sebastian Preissl, Allen Wang, Priscilla D. Negraes, Ryan A. Szeto, Roberto H. Herai, Alik Huseynov, Mariana S. A. Ferraz, Fernando S. Borges, Alexandre H. Kihara, Ashley Byrne, Maximillian Marin, Christopher Vollmers, Angela N. Brooks, Jonathan D. Lautz, Katerina Semendeferi, Beth Shapiro, Gene W. Yeo, Stephen E. P. Smith, Richard E. Green, Alysson R. Muotri
Science. Author manuscript; available in PMC 2021 Mar 29.
Published in final edited form as: Science. 2021 Feb 12; 371(6530): eaax2537. doi: 10.1126/science.aax2537
PMCID:
PMC8006534
AbstractArticlePDF–2.5M
8.
TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene
Valentina Gumina, Claudia Colombrita, Claudia Fallini, Patrizia Bossolasco, Anna Maria Maraschi, John E. Landers, Vincenzo Silani, Antonia Ratti
Biochim Biophys Acta Gene Regul Mech. Author manuscript; available in PMC 2021 Jan 21.
Published in final edited form as: Biochim Biophys Acta Gene Regul Mech. 2019 Sep; 1862(9): 194413. Published online 2019 Aug 2. doi: 10.1016/j.bbagrm.2019.194413
PMCID:
PMC7818381
AbstractArticlePDF–1.7M
9.
miR-27-3p inhibition restore fibroblasts viability in diabetic wound by targeting NOVA1
Peng Zhang, Xiaomei Song, Qirong Dong, Long Zhou, Lei Wang
Aging (Albany NY) 2020 Jul 15; 12(13): 12841–12849. Published online 2020 Jun 26. doi: 10.18632/aging.103266
PMCID:
PMC7377889
AbstractArticlePDF–977K
10.
NOVA1 induction by inflammation and NOVA1 suppression by epigenetic regulation in head and neck squamous cell carcinoma
Eun Kyung Kim, Yoon Ah Cho, Mi-kyoung Seo, Hyunmi Ryu, Byoung Chul Cho, Yoon Woo Koh, Sun Och Yoon
Sci Rep. 2019; 9: 11231. Published online 2019 Aug 2. doi: 10.1038/s41598-019-47755-8
Correction in:
Sci Rep. 2020; 10: 21299.
PMCID:
PMC6677744
AbstractArticlePDF–2.3M
11.
The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies
RJ Buckanovich, YY Yang, RB Darnell
J Neurosci. 1996 Feb 1; 16(3): 1114–1122. doi: 10.1523/JNEUROSCI.16-03-01114.1996
PMCID:
PMC6578795
AbstractPDF–3.8M
12.
NOVA1 directs PTBP1 to hTERT pre-mRNA and promotes telomerase activity in cancer cells
Mohammed E. Sayed, Laura Yuan, Jerome D. Robin, Enzo Tedone, Kimberly Batten, Nicole Dahlson, Woodring E. Wright, Jerry W. Shay, Andrew T. Ludlow
Oncogene. 2019; 38(16): 2937–2952. Published online 2018 Dec 19. doi: 10.1038/s41388-018-0639-8
PMCID:
PMC6474811
AbstractArticlePDF–2.5M
13.
Physical and Functional Interaction between 5-HT6 Receptor and Nova-1
Soon-Hee Kim, Misun Seo, Hongik Hwang, Dong-Min Moon, Gi Hoon Son, Kyungjin Kim, Hyewhon Rhim
Exp Neurobiol. 2019 Feb; 28(1): 17–29. Published online 2019 Jan 21. doi: 10.5607/en.2019.28.1.17
PMCID:
PMC6401546
AbstractArticlePDF–2.8M
14.
NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer
Andrew T. Ludlow, Mandy Sze Wong, Jerome D. Robin, Kimberly Batten, Laura Yuan, Tsung-Po Lai, Nicole Dahlson, Lu Zhang, Ilgen Mender, Enzo Tedone, Mohammed E. Sayed, Woodring E. Wright, Jerry W. Shay
Nat Commun. 2018; 9: 3112. Published online 2018 Aug 6. doi: 10.1038/s41467-018-05582-x
PMCID:
PMC6079032
AbstractArticlePDF–1.7M
15.
NOVA1 acts as an oncogene in melanoma via regulating FOXO3a expression
Xin Yu, Heyi Zheng, Matthew T.V. Chan, William K.K. Wu
J Cell Mol Med. 2018 May; 22(5): 2622–2630. Published online 2018 Mar 2. doi: 10.1111/jcmm.13527
PMCID:
PMC5908123
AbstractArticlePDF–3.1M
16.
17β-estradiol regulates the RNA binding protein Nova1, which then regulates the alternative splicing of estrogen receptor-β in the aging female rat brain
Cody L. Shults, Caitlin B. Dingwall, Chun K. Kim, Elena Pinceti, Yathindar S. Rao, Toni R. Pak
Neurobiol Aging. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Neurobiol Aging. 2018 Jan; 61: 13–22. Published online 2017 Sep 14. doi: 10.1016/j.neurobiolaging.2017.09.005
PMCID:
PMC5705455
AbstractArticlePDF–1.2M
17.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
18.
RNA binding protein Nova1 promotes tumor growth in vivo and its potential mechanism as an oncogene may due to its interaction with GABAA Receptor-γ2
Yi-An Zhang, Hai-Ning Liu, Ji-Min Zhu, Dan-Ying Zhang, Xi-Zhong Shen, Tao-Tao Liu
J Biomed Sci. 2016; 23: 71. Published online 2016 Oct 12. doi: 10.1186/s12929-016-0288-6
PMCID:
PMC5062898
AbstractArticlePDF–1.4M
19.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
20.
An alternative splicing program promotes adipose tissue thermogenesis
Santiago Vernia, Yvonne JK Edwards, Myoung Sook Han, Julie Cavanagh-Kyros, Tamera Barrett, Jason K Kim, Roger J Davis
eLife. 2016; 5: e17672. Published online 2016 Sep 16. doi: 10.7554/eLife.17672
PMCID:
PMC5026472
AbstractArticlePDF–3.1M

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